Systems Thinking in Medicine and New Drug Discovery

Systems Thinking in Medicine and New Drug Discovery PDF Author: Robert E. Smith
Publisher: Cambridge Scholars Publishing
ISBN: 1527523667
Category : Medical
Languages : en
Pages : 632

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Book Description
Total Quality Management (TQM) and systems thinking are being used to improve all aspects of human health. This first book in a two-volume set details how the healthcare community is working with patients and their caregivers to improve healthcare and reduce its costs. Systems-based thinking encourages us to work together to look at the effects of new drugs on entire systems and not just single molecular targets. It also leads us to a better understanding of genetics and epigenetics, as well as the deep ecology of the human body. The healthcare community is developing targeted therapies that stimulate our own bodies to cure ourselves and eliminate the need for animal testing. This book will appeal to specialists, who will find recommendations on safer materials for 3D bioprinting and ways to analyze dietary supplements for toxic contaminants, and physicians, pharmacists and non-professionals, who will learn the important different ways that dietary supplements and prescription drugs are developed, sold and marketed.

Systems Thinking in Medicine and New Drug Discovery

Systems Thinking in Medicine and New Drug Discovery PDF Author: Robert E. Smith
Publisher: Cambridge Scholars Publishing
ISBN: 1527523667
Category : Medical
Languages : en
Pages : 632

Get Book

Book Description
Total Quality Management (TQM) and systems thinking are being used to improve all aspects of human health. This first book in a two-volume set details how the healthcare community is working with patients and their caregivers to improve healthcare and reduce its costs. Systems-based thinking encourages us to work together to look at the effects of new drugs on entire systems and not just single molecular targets. It also leads us to a better understanding of genetics and epigenetics, as well as the deep ecology of the human body. The healthcare community is developing targeted therapies that stimulate our own bodies to cure ourselves and eliminate the need for animal testing. This book will appeal to specialists, who will find recommendations on safer materials for 3D bioprinting and ways to analyze dietary supplements for toxic contaminants, and physicians, pharmacists and non-professionals, who will learn the important different ways that dietary supplements and prescription drugs are developed, sold and marketed.

Systems Thinking in Medicine and New Drug Discovery

Systems Thinking in Medicine and New Drug Discovery PDF Author: Robert E. Smith
Publisher: Cambridge Scholars Publishing
ISBN: 1527523772
Category : Medical
Languages : en
Pages : 347

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Book Description
This second book in a two-volume set tells how the healthcare community is working with patients and their caregivers to help improve health using P4 medicine, proper nutrition and a healthy lifestyle. The healthcare community is finding ways to predict one’s susceptibility to diseases, so they can be prevented from occurring, when possible. When diseases do emerge, it is developing personalized therapies and ways for patients to participate in their own healthcare. At the same time, systems thinking dispels many misconceptions, such as ‘natural’ foods and ‘superfoods’. In fact, the only true superfood is mother’s breast milk. Also, dietary antioxidants prevent inflammation by activating our natural antioxidant system (Nrf2). However, environmental toxins can counteract our best efforts. Still, systems thinking encourages us to fix the problem and not the blame. This book will appeal to professionals, non-professionals and patients, who can learn how to improve healthcare and prevent diseases, while reversing the effects of global climate change.

The Master Adaptive Learner

The Master Adaptive Learner PDF Author: William Cutrer
Publisher: Elsevier Health Sciences
ISBN: 032371112X
Category : Medical
Languages : en
Pages : 242

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Book Description
Tomorrow’s best physicians will be those who continually learn, adjust, and innovate as new information and best practices evolve, reflecting adaptive expertise in response to practice challenges. As the first volume in the American Medical Association’s MedEd Innovation Series, The Master Adaptive Learner is an instructor-focused guide covering models for how to train and teach future clinicians who need to develop these adaptive skills and utilize them throughout their careers. Explains and clarifies the concept of a Master Adaptive Learner: a metacognitive approach to learning based on self-regulation that fosters the success and use of adaptive expertise in practice. Contains both theoretical and practical material for instructors and administrators, including guidance on how to implement a Master Adaptive Learner approach in today’s institutions. Gives instructors the tools needed to empower students to become efficient and successful adaptive learners. Helps medical faculty and instructors address gaps in physician training and prepare new doctors to practice effectively in 21st century healthcare systems. One of the American Medical Association Change MedEd initiatives and innovations, written and edited by members of the ACE (Accelerating Change in Medical Education) Consortium – a unique, innovative collaborative that allows for the sharing and dissemination of groundbreaking ideas and projects.

Systems Thinking for Health Systems Strengthening

Systems Thinking for Health Systems Strengthening PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241563893
Category : Business & Economics
Languages : en
Pages : 113

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Book Description
Makes the case for systems thinking in an easily accessible form for a broad interdisciplinary audience, including health system stewards, programme implementers, researchers, evaluators, and funding partners.

Artificial Intelligence in Healthcare

Artificial Intelligence in Healthcare PDF Author: Adam Bohr
Publisher: Academic Press
ISBN: 0128184396
Category : Computers
Languages : en
Pages : 385

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Book Description
Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. Highlights different data techniques in healthcare data analysis, including machine learning and data mining Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks Includes applications and case studies across all areas of AI in healthcare data

Applied Systems Thinking for Health Systems Research

Applied Systems Thinking for Health Systems Research PDF Author: Don de Savigny
Publisher: Open University Press
ISBN: 9780335261321
Category : Medical
Languages : en
Pages : 0

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Book Description
Patient safety in health systems has become more and more important as a theme in health research, and so it is not surprising to see a growing interest in applying systems thinking to healthcare. However there is a difficulty - health systems are very complex and constantly adapting to respond to core drivers and fit needs. How do you apply systems thinking in this situation, and what methods are available? National health authorities, international donors and research practitioners need to know the "how-to" of conducting health systems research from a systems thinking perspective. This book will fill this gap and provide a range of tools that give clear guidance of ways to carry out systems thinking in health, with real-world examples. These methodologies include: - System dynamics and causal loops - Network analysis - Outcome mapping - Soft systems methodology And many more. Written by an international team of experts in health research, this handbook will be essential reading for those working in or researching public health, health policy, health systems, global health, service improvement and innovation in practice.. "For those working in the health sector, the relevance and value of systems thinking as a concept is evident. However, operationalization of this concept has been a challenge. With this new book, health researchers have a detailed guide for applying system thinking tools in day-to-day operations to identify and solve issues related to health policy and systems." Ghaffar Abdul, Executive Director of the Alliance for Health Policy and Systems Research, Switzerland "This book is the first to present practical options for applying systems thinking to understand complexity in health systems. The editors compile an essential collection of practical tools for understanding complex problems and framing research questions, as well as for determining and managing related solutions. Each tool is presented through an accessible summary of the method and the theory upon which it is based, as well as a real-world example. It will be a valuable resource for teaching and practice." Ligia Paina, PhD, Assistant Professor, Bloomberg School of Public Health, Johns Hopkins University, USA "This keenly-awaited book offers a lucid and comprehensive discussion on how to research complex health systems. Health systems are facing a rapid change and increased complexity, with well-designed solutions often leading to unintended consequences. The book provides invaluable help in navigating this complexity and applying rigorous as well as pragmatic approaches to capturing dynamic interactions between system elements and causal loops. The authors op

Crossing the Global Quality Chasm

Crossing the Global Quality Chasm PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309477891
Category : Medical
Languages : en
Pages : 399

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Book Description
In 2015, building on the advances of the Millennium Development Goals, the United Nations adopted Sustainable Development Goals that include an explicit commitment to achieve universal health coverage by 2030. However, enormous gaps remain between what is achievable in human health and where global health stands today, and progress has been both incomplete and unevenly distributed. In order to meet this goal, a deliberate and comprehensive effort is needed to improve the quality of health care services globally. Crossing the Global Quality Chasm: Improving Health Care Worldwide focuses on one particular shortfall in health care affecting global populations: defects in the quality of care. This study reviews the available evidence on the quality of care worldwide and makes recommendations to improve health care quality globally while expanding access to preventive and therapeutic services, with a focus in low-resource areas. Crossing the Global Quality Chasm emphasizes the organization and delivery of safe and effective care at the patient/provider interface. This study explores issues of access to services and commodities, effectiveness, safety, efficiency, and equity. Focusing on front line service delivery that can directly impact health outcomes for individuals and populations, this book will be an essential guide for key stakeholders, governments, donors, health systems, and others involved in health care.

Overcoming Obstacles in Drug Discovery and Development

Overcoming Obstacles in Drug Discovery and Development PDF Author: Kan He
Publisher: Elsevier
ISBN: 0128173394
Category : Medical
Languages : en
Pages : 448

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Book Description
Overcoming Obstacles in Drug Discovery and Development uses real-world case studies to illustrate how critical thinking and problem solving skills are applied in the discovery and development of drugs. It also shows how developing critical thinking to overcome issues plays an essential role in the process. Modern drug discovery and development is a highly complex undertaking that requires scientific and professional expertise to be successful. After the identification of a molecular entity for treating a medical condition, challenges inevitably arise during the subsequent development to understand and characterize the biological profile; feedback from scientists is used to fine-tune the molecular entity to obtain an effective and safe product. In this process, the discovery team may identify unexpected safety issues and new medical disorders for treatment by the molecular entity. Invariably inherent in this complex undertaking are miscues, mistakes, and unexpected problems that can derail development and throw timetables into disarray, potentially leading to failure in the development of a medically useful drug. Addressing critical unexpected problems during development often requires scientists to utilize critical thinking and imaginative problem-solving skills. Overcoming Obstacles in Drug Discovery and Development will be essential to young scientists to help learn the skills to successfully face challenges, learn from mistakes, and further develop critical thinking skills. It will also be beneficial to experienced researchers who can learn from the case studies of successful and unsuccessful drug development. Provides real-world case studies in drug discovery and the development of drugs Illustrates the use of critical thinking and problem solving in approaching preclinical and clinical problems in drug discovery and development Illustrates and analyses examples of successes and failures in drug discovery and development that have not previously been reported

Applied Systems Thinking for Health Systems Research: a Methodological Handbook

Applied Systems Thinking for Health Systems Research: a Methodological Handbook PDF Author: Don de Savigny
Publisher: McGraw-Hill Education (UK)
ISBN: 0335261337
Category : Medical
Languages : en
Pages : 266

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Book Description
Patient safety in health systems has become more and more important as a theme in health research, and so it is not surprising to see a growing interest in applying systems thinking to healthcare. However there is a difficulty – health systems are very complex and constantly adapting to respond to core drivers and fit needs. How do you apply systems thinking in this situation, and what methods are available? National health authorities, international donors and research practitioners need to know the “how-to” of conducting health systems research from a systems thinking perspective. This book will fill this gap and provide a range of tools that give clear guidance of ways to carry out systems thinking in health. These methodologies include: System dynamics and causal loops Network analysis Outcome mapping Soft systems methodology Written by an international team of experts in health research, this handbook will be essential reading for those working in or researching public health, health policy, health systems, global health, service improvement and innovation in practice.

Health Design Thinking

Health Design Thinking PDF Author: Bon Ku
Publisher: MIT Press
ISBN: 0262358913
Category : Design
Languages : en
Pages : 228

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Book Description
Applying the principles of human-centered design to real-world health care challenges, from drug packaging to early detection of breast cancer. This book makes a case for applying the principles of design thinking to real-world health care challenges. As health care systems around the globe struggle to expand access, improve outcomes, and control costs, Health Design Thinking offers a human-centered approach for designing health care products and services, with examples and case studies that range from drug packaging and exam rooms to internet-connected devices for early detection of breast cancer. Written by leaders in the field—Bon Ku, a physician and founder of the innovative Health Design Lab at Sidney Kimmel Medical College, and Ellen Lupton, an award-winning graphic designer and curator at Cooper Hewitt Smithsonian Design Museum—the book outlines the fundamentals of design thinking and highlights important products, prototypes, and research in health design. Health design thinking uses play and experimentation rather than a rigid methodology. It draws on interviews, observations, diagrams, storytelling, physical models, and role playing; design teams focus not on technology but on problems faced by patients and clinicians. The book's diverse case studies show health design thinking in action. These include the development of PillPack, which frames prescription drug delivery in terms of user experience design; a credit card–size device that allows patients to generate their own electrocardiograms; and improved emergency room signage. Drawings, photographs, storyboards, and other visualizations accompany the case studies. Copublished with Cooper Hewitt, Smithsonian Design Museum