Research Priorities for Helminth Infections

Research Priorities for Helminth Infections PDF Author: TDR Disease Reference Group on Helminth Infections
Publisher:
ISBN: 9789240688612
Category : Helminthiasis
Languages : en
Pages : 197

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Book Description
"Over a billion people in sub-Saharan Africa, Asia and the Americas are infected with one or more helminth species, causing morbidity that helps maintain the vicious cycle of poverty, decreased productivity, and inadequate socioeconomic development. This report presents an evaluation of current research and challenges in controlling the helminthiases of public health importance, including onchocerciasis, lymphatic filariasis, soil-transmitted helminthiases, schistosomiasis, food-borne trematodiases and taeniasis/cysticercosis. The evaluation covers five major themes -- intervention, epidemiology and surveillance, environmental and social ecology, data and modelling, and fundamental biology. Despite the recent demonstrated successes and expansion of tools for the helminthiases outlined here, and the development of some research capacity, the evaluation found major deficiencies in our current control tools, in diagnostics, and in our fundamental knowledge of helminth biology and transmission dynamics, as well as in capacity and policy for health research. Thus the current research issues are summarized here, and opportunities for improving disease control and reducing poverty are identified. Recommendations are presented to inform public health policy, guide implementation programmes, and focus the research community on the needs of disease control and the opportunities for bettering human welfare. This is one of ten disease and thematic reference group reports that have come out of the TDR Think Tank, all of which have contributed to the development of the Global Report for Research on Infectious Diseases of Poverty, available at: www.who.int/tdr/capacity/global_report ."--Page 4 of cover.

Research Priorities for Helminth Infections

Research Priorities for Helminth Infections PDF Author: TDR Disease Reference Group on Helminth Infections
Publisher:
ISBN: 9789240688612
Category : Helminthiasis
Languages : en
Pages : 197

Get Book

Book Description
"Over a billion people in sub-Saharan Africa, Asia and the Americas are infected with one or more helminth species, causing morbidity that helps maintain the vicious cycle of poverty, decreased productivity, and inadequate socioeconomic development. This report presents an evaluation of current research and challenges in controlling the helminthiases of public health importance, including onchocerciasis, lymphatic filariasis, soil-transmitted helminthiases, schistosomiasis, food-borne trematodiases and taeniasis/cysticercosis. The evaluation covers five major themes -- intervention, epidemiology and surveillance, environmental and social ecology, data and modelling, and fundamental biology. Despite the recent demonstrated successes and expansion of tools for the helminthiases outlined here, and the development of some research capacity, the evaluation found major deficiencies in our current control tools, in diagnostics, and in our fundamental knowledge of helminth biology and transmission dynamics, as well as in capacity and policy for health research. Thus the current research issues are summarized here, and opportunities for improving disease control and reducing poverty are identified. Recommendations are presented to inform public health policy, guide implementation programmes, and focus the research community on the needs of disease control and the opportunities for bettering human welfare. This is one of ten disease and thematic reference group reports that have come out of the TDR Think Tank, all of which have contributed to the development of the Global Report for Research on Infectious Diseases of Poverty, available at: www.who.int/tdr/capacity/global_report ."--Page 4 of cover.

Research Priorities for Helminth Infections

Research Priorities for Helminth Infections PDF Author: TDR Disease Reference Group on Helminth Infections
Publisher: WHO Technical Report
ISBN: 9789241209724
Category : Medical
Languages : en
Pages : 0

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Book Description
Over a billion people in sub-Saharan Africa, Asia and the Americas are infected with one or more helminth species, causing morbidity that helps maintain the vicious cycle of poverty, decreased productivity, and inadequate socioeconomic development. This report presents an evaluation of current research and challenges in controlling the helminthiases of public health importance, including onchocerciasis, lymphatic filariasis, soil-transmitted helminthiases, schistosomiasis, food-borne trematodiases and taeniasis/cysticercosis. The evaluation covers five major themes--intervention, epidemiology and surveillance, environmental and social ecology, data and modelling, and fundamental biology. Despite the recent demonstrated successes and expansion of tools for the helminthiases outlined here, and the development of some research capacity, the evaluation found major deficiencies in our current control tools, in diagnostics, and in our fundamental knowledge of helminth biology and transmission dynamics, as well as in capacity and policy for health research. Thus the current research issues are summarized here, and opportunities for improving disease control and reducing poverty are identified. Recommendations are presented to inform public health policy, guide implementation programs, and focus the research community on the needs of disease control and the opportunities for bettering human welfare. This is one of ten disease and thematic reference group reports that have come out of the TDR Think Tank, all of which have contributed to the development of the Global Report for Research on Infectious Diseases of Poverty.

Disease Control Priorities in Developing Countries

Disease Control Priorities in Developing Countries PDF Author: Dean T. Jamison
Publisher: World Bank Publications
ISBN: 0821361805
Category : Medical
Languages : en
Pages : 1449

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Book Description
Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.

Research Priorities for Zoonoses and Marginalized Infections

Research Priorities for Zoonoses and Marginalized Infections PDF Author: TDR Disease Reference Group on Zoonoses and Marginalized Infectious Diseases of Poverty
Publisher: WHO Technical Report
ISBN: 9789241209717
Category : Medical
Languages : en
Pages : 0

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Book Description
This report provides a review and analysis of the research landscape for zoonoses and marginalized infections which affect poor populations, and a list of research priorities to support disease control. The work is the output of the disease reference group on zoonoses and marginalized infectious diseases (DRG6), which is part of an independent think tank of international experts, established and funded by the Special Programme for Research and Training in Tropical Diseases (TDR), to identify key research priorities through the review of research evidence and input from stakeholder consultations. The report covers a diverse range of diseases including zoonotic helminth protozoa, viral and bacterial infections considered to be neglected and associated with poverty. Disease-specific research issues were elaborated under individual disease sections and many common priorities were readily identified among the disease such as need for new and/or improved drugs and regimens, diagnostics and, where appropriate, vaccines. The disease specific priorities are described as micro priorities compared with the macro level priorities which will drive such policies as the need for improved surveillance; the need for inter-sectoral interaction between health, livestock, agriculture, natural resources and wildlife in tackling the zoonotic diseases; and the need for a true assessment of the burden of the zoonoses. This is one of ten disease and thematic reference group reports that have come out of the TDR Think Tank, all of which have contributed to the development of the Global Report for Research on Infectious Diseases of Poverty.

Controlling Disease Due to Helminth Infections

Controlling Disease Due to Helminth Infections PDF Author: Montresor A.
Publisher: World Health Organization
ISBN: 9241562390
Category : Medical
Languages : en
Pages : 269

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Book Description
Helminth infections are caused by parasitic worms (including tapeworms and roundworms). These diseases are associated with poverty, and in school-age populations in developing countries, intestinal helminth infections rank first among the causes of all communicable and noncommunicable diseases. This book is based on papers presented at an OECD conference, held in Bali, Indonesia in February 2000, which sought to review activities for the control of diseases due to soil-transmitted helminth infections in Indonesia and neighbouring countries.

Helminth Control in School-Age Children

Helminth Control in School-Age Children PDF Author: A. Montresor
Publisher: World Health Organization
ISBN: 9789241545563
Category : Medical
Languages : en
Pages : 90

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Book Description
More than 2000 million people worldwide are affected by schistosomiasis and soil-transmitted helminth (STH) infections and 155 000 deaths are reported each year. These infections are diseases associated with poverty, and in school-age populations in developing countries, intestinal helminth infections rank first among the causes of all communicable and noncommunicable diseases. This book describes a cost-effective approach to the control of these infections, based on the use of periodic parasitological surveys of school population samples. It is intended as a guide for health education managers responsible for implementing community-based programmes.

Research Priorities for Chagas Disease Human African Trypanosomiasis and Leishmaniasis

Research Priorities for Chagas Disease Human African Trypanosomiasis and Leishmaniasis PDF Author: World Health Organization
Publisher:
ISBN: 9789240689992
Category : Electronic books
Languages : en
Pages : 0

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Book Description
The Disease Reference Group on Chagas Disease Human AfricanTrypanosomiasis and Leishmaniasis (DRG3) was part of an independent thinktankof international experts established by the Special Programme for Researchand Training in Tropical Diseases (TDR) to identify key research prioritiesthrough systematic review of research evidence and input from stakeholders. These three distinct insect-borne diseases while caused by related kinetoplastidprotozoan pathogens have dissimilar geographical distributions a reflection oftheir different insect vectors and range of vector contact with humans. Thedisease.

Bench aids for the diagnosis of intestinal parasites

Bench aids for the diagnosis of intestinal parasites PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241515341
Category : Medical
Languages : en
Pages : 32

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Book Description
This second edition of Bench aids for the diagnosis of intestinal parasites is intended both as a practical tool for the diagnosis of intestinal parasitic infections for laboratory and field workers and as a teaching aid for students and trainees. The plates are arranged on two sides: the recto with microphotographs for the identification of eggs larvae trophozoites cysts and oocysts occurring in faeces and the verso dedicated to the different copromicroscopical methods (procedures) and main staining techniques used in parasitology. Special attention has been devoted to all graphical and pictorial contents. The decision to include the outline of an Ascaris lumbricoides egg in its relative size next to each parasitic structure fulfils the intention of visualizing the actual dimensions that the eye needs to be looking for when examining the specimens with a microscope. For each image the size of the parasite and a short description are provided to assist in the microscopical identification. Two summary plates one for helminths and the other for protozoa are also included to provide a visual overview of the different presentations of parasitic elements. The bench aids have been produced in a weatherproof plastic-sealed format that is robust and easy to use at the bench. They are recommended for use by all health workers engaged in the routine diagnosis of intestinal parasitic infections.

Investing to Overcome the Global Impact of Neglected Tropical Diseases

Investing to Overcome the Global Impact of Neglected Tropical Diseases PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241564865
Category : Medical
Languages : en
Pages : 211

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Book Description
"The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.

Preventive Chemotherapy in Human Helminthiasis

Preventive Chemotherapy in Human Helminthiasis PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241547103
Category : Medical
Languages : en
Pages : 75

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Book Description
This manual focuses on how and when a set of low-cost or free drugs should be used in developing countries to control a set of diseases caused by worm infections. Preventive chemotherapy in this context means using drugs that are effective against a broad range of worm infections to simultaneously treat the four most common diseases caused by worms: river blindness (onchocerciasis), elephantiasis (lymphatic filariasis), schistosomiasis, and soil-transmitted helminthiasis. Significant opportunities also exist to integrate these efforts with the prevention and control of diseases such as trachoma. The new approach provides a critical first step in combining treatment regimens for diseases which, although different in themselves, require common resources and delivery strategies for control or elimination.