Antimutagenesis and Anticarcinogenesis Mechanisms

Antimutagenesis and Anticarcinogenesis Mechanisms PDF Author: Delbert M. Shankel
Publisher: Springer Science & Business Media
ISBN: 1468451820
Category : Science
Languages : en
Pages : 573

Get Book

Book Description

Antimutagenesis and Anticarcinogenesis Mechanisms

Antimutagenesis and Anticarcinogenesis Mechanisms PDF Author: Delbert M. Shankel
Publisher: Springer Science & Business Media
ISBN: 1468451820
Category : Science
Languages : en
Pages : 573

Get Book

Book Description


Antimutagenesis and Anticarcinogenesis Mechanisms III

Antimutagenesis and Anticarcinogenesis Mechanisms III PDF Author: Giorgio Bronzetti
Publisher: Springer Science & Business Media
ISBN: 1461529840
Category : Medical
Languages : en
Pages : 486

Get Book

Book Description
Lifestyle, in any part of the world, is associated with the occurrence of major chronic diseases, including coronary heart disease, hypertension, and stroke; many distinct types of cancer; and adult onset diabetes (11,22,70,75). One important element of lifestyle is tobacco use, which appreciably increases the risk of a number of chronic diseases (21). Other lifestyle factors relate to nutritional traditions, alcohol use, and exercise (11,30,58,60,70,71). The underlying evidence is, in part, based on the evidence of specific diseases in relation to dietary habits in a given geographic region, as well as changes in such disease occurrences in migrant populations from a low risk to a high risk area, and vice versa (25,42). Populations that customarily consume fruits and vegetables and also whole grain cereal products generally have a lower risk of cardiovascular diseases and specific types of cancer than populations with a lower intake of such foods, everything else being equal (63). In the last few years, research has provided mechanistic explanations as to the reasons for the protective effects of specific foods. This paper will emphasize the mechanisms whereby cancer risks are reduced by dietary modification.

Antimutagenesis and Anticarcinogenesis Mechanisms II

Antimutagenesis and Anticarcinogenesis Mechanisms II PDF Author: Yukioki Kuroda
Publisher: Springer Science & Business Media
ISBN: 1461595614
Category : Medical
Languages : en
Pages : 480

Get Book

Book Description
The papers are arranged in eight sections, addressing: antimutagens in food; antimutagens and anticarcinogens in environmental toxicology; free radicals; antitumor initiators; antitumor promoters; aspects of mammalian and human genetics; molecular aspects of mutagenesis and antimutageneis; and oncog

Antimutagenesis and Anticarcinogenesis Mechanisms ; 3

Antimutagenesis and Anticarcinogenesis Mechanisms ; 3 PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

Get Book

Book Description


Antimutagenesis and Anticarcinogenesis Mechanisms III

Antimutagenesis and Anticarcinogenesis Mechanisms III PDF Author: Giorgio Bronzetti
Publisher: Springer
ISBN: 9781461529859
Category : Medical
Languages : en
Pages : 494

Get Book

Book Description
Lifestyle, in any part of the world, is associated with the occurrence of major chronic diseases, including coronary heart disease, hypertension, and stroke; many distinct types of cancer; and adult onset diabetes (11,22,70,75). One important element of lifestyle is tobacco use, which appreciably increases the risk of a number of chronic diseases (21). Other lifestyle factors relate to nutritional traditions, alcohol use, and exercise (11,30,58,60,70,71). The underlying evidence is, in part, based on the evidence of specific diseases in relation to dietary habits in a given geographic region, as well as changes in such disease occurrences in migrant populations from a low risk to a high risk area, and vice versa (25,42). Populations that customarily consume fruits and vegetables and also whole grain cereal products generally have a lower risk of cardiovascular diseases and specific types of cancer than populations with a lower intake of such foods, everything else being equal (63). In the last few years, research has provided mechanistic explanations as to the reasons for the protective effects of specific foods. This paper will emphasize the mechanisms whereby cancer risks are reduced by dietary modification.

Advances in Nutrition and Cancer 2

Advances in Nutrition and Cancer 2 PDF Author: Vincenzo Zappia
Publisher: Springer Science & Business Media
ISBN: 1475732309
Category : Medical
Languages : en
Pages : 313

Get Book

Book Description
This volume includes contributions presented at the Second International Sym posium on Nutrition and Cancer, held in Naples, Italy, in October 1998 at the National Tumor Institute "Fondazione Pascale." During the Conference, experts from different disciplines discussed pivotal and timely subjects on the interactions between human nutrition and the development of malignancies. Comparing the themes of this Meeting with those discussed at the First Sympo sium in 1992, the major scientific advancements certainly derive from the extensive use of molecular approaches to perform research in nutrition. Moreover, the fundamental observation of R. Doll and R. Peto (1981), which suggested that at least 35% of all cancers (with large differences among different tumors) might be prevented by dietary regimens, has been definitively confirmed by epidemiological studies. On the other hand, the relationships between diet and cancer are quite intricate and complex; it is difficult, and at the same time not methodologically correct, to reduce them to simple terms. Metabolic and hormonal factors, contaminants and biological agents, and deficiency of specific protective nutrients are all pieces of the same puzzle.

Carcinogens and Anticarcinogens in the Human Diet

Carcinogens and Anticarcinogens in the Human Diet PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309175712
Category : Nature
Languages : en
Pages : 433

Get Book

Book Description
Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease PDF Author: Bharat B. Aggarwal
Publisher: Springer Science & Business Media
ISBN: 0387464018
Category : Medical
Languages : en
Pages : 502

Get Book

Book Description
The medicinal uses of Curcumin (also called turmeric) have been known and described for more than 5000 years. A large body of recent research suggests that curcumin is potentially useful in the treatment of inflammatory diseases, through modulation of numerous molecular targets. This is the first monograph to focus on the potential use of curcumin in the treatment of cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer’s, psoriasis and more.

Plant Polyphenols

Plant Polyphenols PDF Author: Richard W. Hemingway
Publisher: Springer Science & Business Media
ISBN: 9780306442520
Category : Nature
Languages : en
Pages : 1080

Get Book

Book Description
Proceedings of the Second North American Tannin Conference on Plant Polyphenols held in Houghton, Michigan, June 17-21, 1991

Short-Term Test Systems for Detecting Carcinogens

Short-Term Test Systems for Detecting Carcinogens PDF Author: K.H. Norpoth
Publisher: Springer Science & Business Media
ISBN: 3642672027
Category : Medical
Languages : en
Pages : 424

Get Book

Book Description
The varying cancer incidence from country to country and region to region suggests that en vironmental factors play a considerable role in the aetiology of cancer. Whether these factors in the environment moderate the effect of car cinogenic chemicals or whether they might them selves be carcinogenic is not known at the present time. What is known is that there are various chemicals, both naturally occurring and man-made, which can induce cancer in man. In the Western world estimates vary as to how much cancer is occupational in origin; the figures range from 1% to 40%. It is our feeling that probably about 10% of cancer has a direct oc cupational origin. Nevertheless this number is considerable and it behoves us therefore to identify those chemicals which are carcinogenic and to reduce human exposure. Recent work on the mode of action of carcinogenic chemicals suggests that the majority exert their effect through an activation step to give elec trophilic metabolites. Such metabolites have as a common feature the ability to react with cel lular nucleophiles to give covalently bound products. Such reaction will occur after carcino gen treatment of animals with nucleic acids par ticularly in target organs. It is reaction with nucleic acids that provides the basis of a num ber of short-term tests for carcinogens, since the basic composition of DNA is similar in micro-organisms and in human cells.