Treatment–Refractory Schizophrenia

Treatment–Refractory Schizophrenia PDF Author: Peter F. Buckley
Publisher: Springer Science & Business Media
ISBN: 3642452574
Category : Medical
Languages : en
Pages : 230

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Book Description
Schizophrenia is often associated with an inadequate response to pharmacological and non-pharmacological treatments. How to treat patients who have an unsatisfactory response to anti-psychotics, including clozapine - which is unequivocally the most powerful antipsychotic medication for this recalcitrant population - remains a clinical conundrum. A range of adjunctive medications have been tried with mixed results; there has also been renewed interest in the role of neuromodulatory strategies, electroconvulsive therapy, and cognitive and vocational approaches. Perhaps a bright spot for the future lies in the evolution of pharmacogenetic approaches for individualized care. In this book, leading experts from Europe, Australia and the Americas provide a timely appraisal of treatments for the most severely ill schizophrenia patients. This clinically focused book is informed by the latest research on the neurobiology and treatment of schizophrenia. It is comprehensive in scope, covering current treatment options, various add-on approaches, and a range of psychosocial treatments. The contributors are respected experts who have combined their clinical experience with cutting-edge research to provide readers with authoritative information on fundamental aspects of clinical care for schizophrenia.

Treatment–Refractory Schizophrenia

Treatment–Refractory Schizophrenia PDF Author: Peter F. Buckley
Publisher: Springer Science & Business Media
ISBN: 3642452574
Category : Medical
Languages : en
Pages : 230

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Book Description
Schizophrenia is often associated with an inadequate response to pharmacological and non-pharmacological treatments. How to treat patients who have an unsatisfactory response to anti-psychotics, including clozapine - which is unequivocally the most powerful antipsychotic medication for this recalcitrant population - remains a clinical conundrum. A range of adjunctive medications have been tried with mixed results; there has also been renewed interest in the role of neuromodulatory strategies, electroconvulsive therapy, and cognitive and vocational approaches. Perhaps a bright spot for the future lies in the evolution of pharmacogenetic approaches for individualized care. In this book, leading experts from Europe, Australia and the Americas provide a timely appraisal of treatments for the most severely ill schizophrenia patients. This clinically focused book is informed by the latest research on the neurobiology and treatment of schizophrenia. It is comprehensive in scope, covering current treatment options, various add-on approaches, and a range of psychosocial treatments. The contributors are respected experts who have combined their clinical experience with cutting-edge research to provide readers with authoritative information on fundamental aspects of clinical care for schizophrenia.

Management of Complex Treatment-resistant Psychotic Disorders

Management of Complex Treatment-resistant Psychotic Disorders PDF Author: Michael Cummings
Publisher: Cambridge University Press
ISBN: 1108962122
Category : Medical
Languages : en
Pages : 545

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Book Description
This full-color, practical handbook provides a concise, evidence-based psychopharmacological approach to the management of complex treatment-resistant psychotic disorders. Part I focuses uniquely on topics and strategies relevant to treating this challenging patient population. These approaches go beyond standard guidelines while adhering to research and clinically derived data. Part II provides a concise array of information regarding those classes of medications most commonly used when treating complex treatment-resistant psychotic disorders. Each medication guide contains sections including mechanisms of action, typical treatment response, monitoring, dosing and kinetics, medications to avoid in combination/warnings, and take-home pearls. Part III offers tips in brief appendix chapters for managing common issues ranging from loading lithium and valproic acid to the treatment of acute psychomotor agitation. An essential resource for psychiatrists, forensic clinicians, psychiatric trainees, and all mental health professionals involved with, or interested in, the treatment of challenging psychotic disorders.

Therapy-Resistant Schizophrenia

Therapy-Resistant Schizophrenia PDF Author: H. Elkis
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805595123
Category : Medical
Languages : en
Pages : 210

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Book Description
The psychotic symptoms of up to 30% of schizophrenic patients do not respond adequately to treatment with antipsychotic drugs, other than clozapine. These refractory patients are generally among the most disabled of all people with schizophrenia and require special assessment and treatment. This volume presents the latest research and recommendations on the definition, causes and therapy of treatment-resistant schizophrenia (TRS). Methods for identification and optimal management of TRS are reviewed. Clozapine and other atypical antipsychotic drugs which are the primary treatment for TRS, as well as non-pharmacologic treatments such as transcranial magnetic stimulation, cognitive behavior therapy and ECT are discussed in depth. Potential causative factors and identifying features such as genetic factors, poor premorbid functioning, longer duration of untreated psychosis, and biological measures such as structural and functional brain abnormalities are also reviewed in depth in the present volume.

Cognitive Therapy of Schizophrenia

Cognitive Therapy of Schizophrenia PDF Author: David G. Kingdon
Publisher: Guilford Press
ISBN: 1606237713
Category : Psychology
Languages : en
Pages : 219

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Book Description
Drawing on the authors' decades of influential work in the field, this highly practical volume presents an evidence-based cognitive therapy approach for clients with schizophrenia. Guidelines are provided for collaborative assessment and case formulation that enable the clinician to build a strong therapeutic relationship, establish reasonable goals, and tailor treatment to each client's needs. Described in thorough, step-by-step detail are effective techniques for working with delusional beliefs, voices, visions, thought disorders, and negative symptoms; integrating cognitive therapy with other forms of treatment; reducing relapse risks; and enhancing client motivation. Special features include reproducible client handouts and assessment tools.

Psychotic Disorders

Psychotic Disorders PDF Author: Oliver Freudenreich
Publisher: Springer Nature
ISBN: 3030294501
Category : Medical
Languages : en
Pages : 479

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Book Description
This book provides clear and concise guidance for clinicians when they encounter a patient with psychosis, starting with the medical work-up to arrive at a diagnosis and ending with the comprehensive care for patients with established schizophrenia. It covers the optimal use of medications (emphasizing safe use) but also addresses other treatment approaches (psychological treatments, rehabilitation) and the larger societal context of care, including how to work effectively in complex systems. It uniquely condenses the literature into teaching points without simplifying too much, effectively serving as a learning tool for trainees and professionals. For this second edition, the book was extensively updated and its content expanded, with new figures as well. Each chapter begins with an initial summary and includes Tips and Key Points in text boxes. Each chapter also includes links to external websites and additional readings. The book contains clinical and practical wisdom for clinicians who are treating real patients at the front lines, setting it apart from all other texts. Psychotic Disorders is an excellent resource for medical students, early career professionals such as trainees and fellows, and related clinicians seeking additional training and resources, including those in psychiatry, psychology, neurology, and all others.

Culturally Informed Therapy for Schizophrenia

Culturally Informed Therapy for Schizophrenia PDF Author: Amy Weisman de Mamani
Publisher: Oxford University Press
ISBN: 0197500641
Category : Medical
Languages : en
Pages : 193

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Book Description
"This book is primarily designed for clinicians and researchers interested in learning how to conduct an empirically supported, Culturally Informed Therapy for Schizophrenia (CIT-S) that integrates core components of evidenced based family therapy. It is estimated that approximately one percent of adults in the United States will be diagnosed with schizophrenia or a related schizophrenia spectrum disorder (SSD). Without treatment, prognosis is generally poor. Fortunately, traditional family therapies have shown increasing promise in reducing relapse rates and improving mental health for this population. As more and more societies become multicultural, however, there is an increasing expectation that mental health providers will also be prepared to meet the needs of unique and culturally diverse clients in an efficient, skillful, and culturally relevant manner. CIT-S is a 15-week, family-focused, cognitive behavioral approach for managing schizophrenia spectrum disorders. The intervention draws upon clients' cultural beliefs, practices, and traditions to help them conceptualize and manage mental illness. It aims to improve the quality of clients' lives in a manner that is in line with their values and takes into account their cultural norms when discussing important issues and addressing challenges (such as mental illness) within the family. CIT-S contains five distinct modules: 1) Family Collectivism 2) Psychoeducation 3) Spirituality 4) Communication Training and 5) Problem Solving. For each module, a detailed rationale, background information, therapy instructions, suggested homework assignments, and a sample case vignette is provided in an accessible, easy-to-use, manner"--

Life-Threatening Effects of Antipsychotic Drugs

Life-Threatening Effects of Antipsychotic Drugs PDF Author: Peter Manu
Publisher: Academic Press
ISBN: 0128033908
Category : Medical
Languages : en
Pages : 394

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Book Description
Life-Threatening Effects of Antipsychotic Drugs describes in detail more than 20 life-threatening effects associated with antipsychotics, presents the best available data on their incidence and case fatality, and gives comprehensive advice on diagnosis, management and preventive strategies. In addition, the book discusses the benefit of antipsychotic medication in a range of therapeutic indications, and demonstrates the gain in life-expectancy associated with clozapine use in severe mental illness despite its serious, potentially life-threatening adverse effects. Covers cardiovascular, neurological, muscular, hematological, gastrointestinal, autonomic and metabolic effects Gives advice on risk factors, confounding diagnoses and measures to minimise seriousness Discusses clozapine rechallenge after each of its serious adverse reactions Makes suggestions for optimum management of somatic disease in those with severe mental illness, to improve life-expectancy Includes data on post-mortem considerations

INT-Integrated Neurocognitive Therapy for Schizophrenia Patients

INT-Integrated Neurocognitive Therapy for Schizophrenia Patients PDF Author: Volker Roder
Publisher: Springer
ISBN: 3319132458
Category : Psychology
Languages : en
Pages : 141

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Book Description
This book contains concrete and step by step information with many practical examples. It is in line with the most actual international empirical findings about schizophrenia and contains the most updated therapy approach being available currently. The techniques and exercises (partly computer-based) are described in detail. Case examples point out specific therapeutic situations and teach the therapist how to cope with complicated group and individual demands. Assessment for patient selection, differential indication and therapy control within a multi-dimensional treatment and rehabilitation system are discussed. INT was evaluated successfully in an international randomised multi-centre study. In the meantime it is implemented in many clinical settings in German speaking countries. Integrated Neurocognitive Therapy (INT) is a cognitive remediation therapy approach. INT is the first treatment manual comprising all MATRICS areas (Measurement and Treatment Research to Improve Cognition in Schizophrenia). The NIMH (National Institute of Mental Health, USA) initiated this MATRICS initiative. MATRICS defines 11 neurocognitive and social cognitive areas of functioning being relevant for patients with schizophrenia. The improvement of these areas in a group therapy is the main goal of INT. INT is based on IPT (Integrated Psychological Therapy, Roder et al 2010). It is a resource and a recovery oriented intervention to enhance also therapy motivation and self-esteem and to reduce negative symptoms. Therapy focuses especially on group processes and the exercises augment transfer and generalisation to daily life. As a meta goal INT intends to amend life quality and the reintegration of the patients in the community. The presented manual offers the clinicians a practically orientated guide for carrying out INT.

First Episode Psychosis

First Episode Psychosis PDF Author: Katherine J. Aitchison
Publisher: CRC Press
ISBN: 0429524145
Category : Medical
Languages : en
Pages : 152

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Book Description
The new edition of this popular handbook has been thoroughly updated to include the latest data concerning treatment of first-episode patients. Drawing from their experience, the authors discuss the presentation and assessment of the first psychotic episode and review the appropriate use of antipsychotic agents and psychosocial approaches in effective management. This is an authoritative text written by a team of highly respected authors for psychiatrists, neurologists, primary care practitioners and health care professional working in psychiatry. Drawing from their experience, the presentation and assessment of the first psychotic episode are discussed, details regarding antipsychotic drugs and their appropriate use are reviewed and psychosocial approaches are examined. The resulting book offers a concise and valuable guide to those wishing to review the latest proposals for the treatment of first-episode psychosis supported by up-to-date references, in a single publication.

Cognitive-Behavioral Therapy of Schizophrenia

Cognitive-Behavioral Therapy of Schizophrenia PDF Author: David G. Kingdon
Publisher: Psychology Press
ISBN: 1000446190
Category : Psychology
Languages : en
Pages : 113

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Book Description
Cognitive-behavioural therapy has been successfully employed in the treatment of such problems as depression, panic disorder and phobias. Providing an approach to patients with the most intractable problems, this book details the practical application of cognitive-behavioural therapy to the pervasive disorder of schizophrenia. The techniques described in this book, drawn from relevant theory and research, are designed to complement other treatments for schizophrenia, including medication, rehabilitation and family therapies.; Making a clear distinction between the diagnosis of schizophrenia and the debilitating label of insanity, the authors contend that people with this disorder are not inherently irrational but instead suffer from a circumscribed set of irrational beliefs. The book presents easily learned techniques that professionals can employ to help patients alleviate the impact of these beliefs, and start drawing upon the strengths and rationality they possess to improve their daily lives.; Illustrated with numerous case examples, this book describes how to: work with the person to construct credible explanations of distressing and disabling symptoms; explore the personal significance of life events and circumstances and their interactions with the person's strengths and vulnerabilities; introduce reality testing for hallucinations and delusions; disentangle thought Disorder And Ameliorate Negative Symptoms; And Demystify Psychotic symptoms for individuals and their families. The book also delineates the relationship of thought, identity, insight and coping strategies to schizophrenia.; This text should be of interest to professionals working with people suffering from schizophrenia - from psychologists, psychiatrists and residential care workers to social workers, occupational therapists and nursing staff - as well as to students in these fields.