The Role of Theory in Advancing 21st-Century Biology

The Role of Theory in Advancing 21st-Century Biology PDF Author: Committee on Defining and Advancing the Conceptual Basis of Biological Sciences in the 21st Century
Publisher: National Academies Press
ISBN: 9780309112499
Category : Science
Languages : en
Pages : 0

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Book Description
Although its importance is not always recognized, theory is an integral part of all biological research. Biologists' theoretical and conceptual frameworks inform every step of their research, affecting what experiments they do, what techniques and technologies they develop and use, and how they interpret their data. By examining how theory can help biologists answer questions like "What are the engineering principles of life?" or "How do cells really work?" the report shows how theory synthesizes biological knowledge from the molecular level to the level of whole ecosystems. The book concludes that theory is already an inextricable thread running throughout the practice of biology; but that explicitly giving theory equal status with other components of biological research could help catalyze transformative research that will lead to creative, dynamic, and innovative advances in our understanding of life.

The Role of Theory in Advancing 21st-Century Biology

The Role of Theory in Advancing 21st-Century Biology PDF Author: Committee on Defining and Advancing the Conceptual Basis of Biological Sciences in the 21st Century
Publisher: National Academies Press
ISBN: 9780309112499
Category : Science
Languages : en
Pages : 0

Get Book

Book Description
Although its importance is not always recognized, theory is an integral part of all biological research. Biologists' theoretical and conceptual frameworks inform every step of their research, affecting what experiments they do, what techniques and technologies they develop and use, and how they interpret their data. By examining how theory can help biologists answer questions like "What are the engineering principles of life?" or "How do cells really work?" the report shows how theory synthesizes biological knowledge from the molecular level to the level of whole ecosystems. The book concludes that theory is already an inextricable thread running throughout the practice of biology; but that explicitly giving theory equal status with other components of biological research could help catalyze transformative research that will lead to creative, dynamic, and innovative advances in our understanding of life.

The Role of Theory in Advancing 21st-Century Biology

The Role of Theory in Advancing 21st-Century Biology PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 030913417X
Category : Science
Languages : en
Pages : 208

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Book Description
Although its importance is not always recognized, theory is an integral part of all biological research. Biologists' theoretical and conceptual frameworks inform every step of their research, affecting what experiments they do, what techniques and technologies they develop and use, and how they interpret their data. By examining how theory can help biologists answer questions like "What are the engineering principles of life?" or "How do cells really work?" the report shows how theory synthesizes biological knowledge from the molecular level to the level of whole ecosystems. The book concludes that theory is already an inextricable thread running throughout the practice of biology; but that explicitly giving theory equal status with other components of biological research could help catalyze transformative research that will lead to creative, dynamic, and innovative advances in our understanding of life.

The Role of Theory in Advancing 21st-Century Biology

The Role of Theory in Advancing 21st-Century Biology PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309112494
Category : Science
Languages : en
Pages : 209

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Book Description
Although its importance is not always recognized, theory is an integral part of all biological research. Biologists' theoretical and conceptual frameworks inform every step of their research, affecting what experiments they do, what techniques and technologies they develop and use, and how they interpret their data. By examining how theory can help biologists answer questions like "What are the engineering principles of life?" or "How do cells really work?" the report shows how theory synthesizes biological knowledge from the molecular level to the level of whole ecosystems. The book concludes that theory is already an inextricable thread running throughout the practice of biology; but that explicitly giving theory equal status with other components of biological research could help catalyze transformative research that will lead to creative, dynamic, and innovative advances in our understanding of life.

Mathematics and 21st Century Biology

Mathematics and 21st Century Biology PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309095840
Category : Science
Languages : en
Pages : 163

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Book Description
The exponentially increasing amounts of biological data along with comparable advances in computing power are making possible the construction of quantitative, predictive biological systems models. This development could revolutionize those biology-based fields of science. To assist this transformation, the U.S. Department of Energy asked the National Research Council to recommend mathematical research activities to enable more effective use of the large amounts of existing genomic information and the structural and functional genomic information being created. The resulting study is a broad, scientifically based view of the opportunities lying at the mathematical science and biology interface. The book provides a review of past successes, an examination of opportunities at the various levels of biological systemsâ€" from molecules to ecosystemsâ€"an analysis of cross-cutting themes, and a set of recommendations to advance the mathematics-biology connection that are applicable to all agencies funding research in this area.

Towards a Theory of Development

Towards a Theory of Development PDF Author: Alessandro Minelli
Publisher: Oxford University Press, USA
ISBN: 0199671435
Category : Science
Languages : en
Pages : 299

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Book Description
Is it possible to explain and predict the development of living things? What is development? Articulate answers to these seemingly innocuous questions are far from straightforward. To date, no systematic, targeted effort has been made to construct a unifying theory of development. This novel work offers a unique exploration of the foundations of ontogeny by asking how the development of living things should be understood. It explores the key concepts of developmental biology, asks whether general principles of development can be discovered, and examines the role of models and theories. The two editors (one a biologist with long interest in the theoretical aspects of his discipline, the other a philosopher of science who has mainly worked on biological systems) have assembled a team of leading contributors who are representative of the scientific and philosophical community within which a diversity of thoughts are growing, and out of which a theory of development may eventually emerge. They analyse a wealth of approaches to concepts, models and theories of development, such as gene regulatory networks, accounts based on systems biology and on physics of soft matter, the different articulations of evolution and development, symbiont-induced development, as well as the widely discussed concepts of positional information and morphogenetic field, the idea of a 'programme' of development and its critiques, and the long-standing opposition between preformationist and epigenetic conceptions of development. Towards a Theory of Development is primarily aimed at students and researchers in the fields of 'evo-devo', developmental biology, theoretical biology, systems biology, biophysics, and the philosophy of science.

The Theory of Ecology

The Theory of Ecology PDF Author: Samuel M. Scheiner
Publisher: University of Chicago Press
ISBN: 0226736873
Category : Science
Languages : en
Pages : 416

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Book Description
Despite claims to the contrary, the science of ecology has a long history of building theories. Many ecological theories are mathematical, computational, or statistical, though, and rarely have attempts been made to organize or extrapolate these models into broader theories. The Theory of Ecology brings together some of the most respected and creative theoretical ecologists of this era to advance a comprehensive, conceptual articulation of ecological theories. The contributors cover a wide range of topics, from ecological niche theory to population dynamic theory to island biogeography theory. Collectively, the chapters ably demonstrate how theory in ecology accounts for observations about the natural world and how models provide predictive understandings. It organizes these models into constitutive domains that highlight the strengths and weaknesses of ecological understanding. This book is a milestone in ecological theory and is certain to motivate future empirical and theoretical work in one of the most exciting and active domains of the life sciences.

Review of the Department of Energy's Genomics: GTL Program

Review of the Department of Energy's Genomics: GTL Program PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309180716
Category : Science
Languages : en
Pages : 102

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Book Description
The U.S. Department of Energy (DOE) promotes scientific and technological innovation to advance the national, economic, and energy security of the United States. Recognizing the potential of microorganisms to offer new energy alternatives and remediate environmental contamination, DOE initiated the Genomes to Life program, now called Genomics: GTL, in 2000. The program aims to develop a predictive understanding of microbial systems that can be used to engineer systems for bioenergy production and environmental remediation, and to understand carbon cycling and sequestration. This report provides an evaluation of the program and its infrastructure plan. Overall, the report finds that GTL's research has resulted in and promises to deliver many more scientific advancements that contribute to the achievement of DOE's goals. However, the DOE's current plan for building four independent facilities for protein production, molecular imaging, proteome analysis, and systems biology sequentially may not be the most cost-effective, efficient, and scientifically optimal way to provide this infrastructure. As an alternative, the report suggests constructing up to four institute-like facilities, each of which integrates the capabilities of all four of the originally planned facility types and focuses on one or two of DOE's mission goals. The alternative infrastructure plan could have an especially high ratio of scientific benefit to cost because the need for technology will be directly tied to the biology goals of the program.

The Philosophy of Biology

The Philosophy of Biology PDF Author: Kostas Kampourakis
Publisher: Springer Science & Business Media
ISBN: 9400765371
Category : Philosophy
Languages : en
Pages : 765

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Book Description
This book brings together for the first time philosophers of biology to write about some of the most central concepts and issues in their field from the perspective of biology education. The chapters of the book cover a variety of topics ranging from traditional ones, such as biological explanation, biology and religion or biology and ethics, to contemporary ones, such as genomics, systems biology or evolutionary developmental biology. Each of the 30 chapters covers the respective philosophical literature in detail and makes specific suggestions for biology education. The aim of this book is to inform biology educators, undergraduate and graduate students in biology and related fields, students in teacher training programs, and curriculum developers about the current state of discussion on the major topics in the philosophy of biology and its implications for teaching biology. In addition, the book can be valuable to philosophers of biology as an introductory text in undergraduate and graduate courses.

Inverse Infrastructures

Inverse Infrastructures PDF Author: Tineke M. Egyedi
Publisher: Edward Elgar Publishing
ISBN: 1781952299
Category : Business & Economics
Languages : en
Pages : 337

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Book Description
'The traditional analysis of infrastructure networks has provided the conceptual rationalization for centralized monopolies for a century. In recent years, liberalization has shown that much wider participation can be beneficial. Innovative development in decentralized networks can be driven from below if government policies permit it, as vividly demonstrated by the Internet. This book contributes to a much needed exploration into the characteristics and implications of decentralized networks being driven from below, introducing new perspectives on the conception and analysis of infrastructure networks.' William H. Melody, Aalborg University, Denmark and Delft University of Technology, The Netherlands The notion of inverse infrastructures that is, bottom-up, user-driven, self-organizing networks gives us a fresh perspective on the omnipresent infrastructure systems that support our economy and structure our way of living. This fascinating book considers the emergence of inverse infrastructures as a new phenomenon that will have a vast impact on consumers, industry and policy. Using a wide range of theories, from institutional economics to complex adaptive systems, it explores the mechanisms and incentives for the rise of these alternatives to large-scale infrastructures and points to their potential disruptive effect on conventional markets and governance models. The approach in this unique book challenges the existing literature on infrastructures, which primarily focuses on large technical systems (LTSs). Rather, this study highlights unprecedented developments, analyzing the differences and complementarity between LTSs and inverse infrastructures. It illustrates that even large infrastructures need not require a blueprint design or top-down and centralized control to run efficiently. The expert contributors draw upon a captivating and wide-ranging set of case studies, including: Wikipedia; wind energy cooperatives, Wireless Leiden, rural telecom in developing countries, local radio and television distribution, the collection of waste paper, syngas infrastructure design, and e-government projects. The book discusses the feasibility of temporary infrastructures and unheard of ownership arrangements, and concludes that inverse networks represent a critical transformation of the accepted model of infrastructure development. Laying a foundation for future research in the area and suggesting ways to bridge the gap between policy and practice, this path-breaking book will prove a riveting read for academics, students and researchers across a number of disciplines including economics, business, management, innovation, and technology and policy studies.

A Framework for K-12 Science Education

A Framework for K-12 Science Education PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309217423
Category : Education
Languages : en
Pages : 400

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Book Description
Science, engineering, and technology permeate nearly every facet of modern life and hold the key to solving many of humanity's most pressing current and future challenges. The United States' position in the global economy is declining, in part because U.S. workers lack fundamental knowledge in these fields. To address the critical issues of U.S. competitiveness and to better prepare the workforce, A Framework for K-12 Science Education proposes a new approach to K-12 science education that will capture students' interest and provide them with the necessary foundational knowledge in the field. A Framework for K-12 Science Education outlines a broad set of expectations for students in science and engineering in grades K-12. These expectations will inform the development of new standards for K-12 science education and, subsequently, revisions to curriculum, instruction, assessment, and professional development for educators. This book identifies three dimensions that convey the core ideas and practices around which science and engineering education in these grades should be built. These three dimensions are: crosscutting concepts that unify the study of science through their common application across science and engineering; scientific and engineering practices; and disciplinary core ideas in the physical sciences, life sciences, and earth and space sciences and for engineering, technology, and the applications of science. The overarching goal is for all high school graduates to have sufficient knowledge of science and engineering to engage in public discussions on science-related issues, be careful consumers of scientific and technical information, and enter the careers of their choice. A Framework for K-12 Science Education is the first step in a process that can inform state-level decisions and achieve a research-grounded basis for improving science instruction and learning across the country. The book will guide standards developers, teachers, curriculum designers, assessment developers, state and district science administrators, and educators who teach science in informal environments.