The Mathematics and Mechanics of Biological Growth

The Mathematics and Mechanics of Biological Growth PDF Author: Alain Goriely
Publisher: Springer
ISBN: 038787710X
Category : Mathematics
Languages : en
Pages : 646

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Book Description
This monograph presents a general mathematical theory for biological growth. It provides both a conceptual and a technical foundation for the understanding and analysis of problems arising in biology and physiology. The theory and methods are illustrated on a wide range of examples and applications. A process of extreme complexity, growth plays a fundamental role in many biological processes and is considered to be the hallmark of life itself. Its description has been one of the fundamental problems of life sciences, but until recently, it has not attracted much attention from mathematicians, physicists, and engineers. The author herein presents the first major technical monograph on the problem of growth since D’Arcy Wentworth Thompson’s 1917 book On Growth and Form. The emphasis of the book is on the proper mathematical formulation of growth kinematics and mechanics. Accordingly, the discussion proceeds in order of complexity and the book is divided into five parts. First, a general introduction on the problem of growth from a historical perspective is given. Then, basic concepts are introduced within the context of growth in filamentary structures. These ideas are then generalized to surfaces and membranes and eventually to the general case of volumetric growth. The book concludes with a discussion of open problems and outstanding challenges. Thoughtfully written and richly illustrated to be accessible to readers of varying interests and background, the text will appeal to life scientists, biophysicists, biomedical engineers, and applied mathematicians alike.

The Mathematics and Mechanics of Biological Growth

The Mathematics and Mechanics of Biological Growth PDF Author: Alain Goriely
Publisher: Springer
ISBN: 038787710X
Category : Mathematics
Languages : en
Pages : 646

Get Book

Book Description
This monograph presents a general mathematical theory for biological growth. It provides both a conceptual and a technical foundation for the understanding and analysis of problems arising in biology and physiology. The theory and methods are illustrated on a wide range of examples and applications. A process of extreme complexity, growth plays a fundamental role in many biological processes and is considered to be the hallmark of life itself. Its description has been one of the fundamental problems of life sciences, but until recently, it has not attracted much attention from mathematicians, physicists, and engineers. The author herein presents the first major technical monograph on the problem of growth since D’Arcy Wentworth Thompson’s 1917 book On Growth and Form. The emphasis of the book is on the proper mathematical formulation of growth kinematics and mechanics. Accordingly, the discussion proceeds in order of complexity and the book is divided into five parts. First, a general introduction on the problem of growth from a historical perspective is given. Then, basic concepts are introduced within the context of growth in filamentary structures. These ideas are then generalized to surfaces and membranes and eventually to the general case of volumetric growth. The book concludes with a discussion of open problems and outstanding challenges. Thoughtfully written and richly illustrated to be accessible to readers of varying interests and background, the text will appeal to life scientists, biophysicists, biomedical engineers, and applied mathematicians alike.

Morpho-elasticity

Morpho-elasticity PDF Author: Alain Goriely
Publisher: Springer
ISBN: 9780387877617
Category : Mathematics
Languages : en
Pages : 300

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Book Description
Growth plays a fundamental role in many biological processes and is considered to be the hallmark of life itself. It is a process of extreme complexity and its description has been one of the fundamental problems of life sciences. However, until recently, it has not attracted much attention from mathematicians, physicists, and mechanicians. The goal of this monograph is to present the state of knowledge in the mechanics of growth, to provide a rigorous foundation and, to offer a set of mathematical tools for the analysis of specific problems arising in biology accessible to mathematicians, physicists, and biologists. Simple examples, applications and building discussions are included. The emphasis of the book is on the kinematics and mechanics of growth. Accordingly, the three first parts of the book are: Growth of curves and lamentary structure, Growth of surfaces, membranes, and shells, and Volumetric growth.

Exploring Mathematical Modeling in Biology Through Case Studies and Experimental Activities

Exploring Mathematical Modeling in Biology Through Case Studies and Experimental Activities PDF Author: Rebecca Sanft
Publisher: Academic Press
ISBN: 0128195967
Category : Science
Languages : en
Pages : 262

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Book Description
Exploring Mathematical Modeling in Biology through Case Studies and Experimental Activities provides supporting materials for courses taken by students majoring in mathematics, computer science or in the life sciences. The book's cases and lab exercises focus on hypothesis testing and model development in the context of real data. The supporting mathematical, coding and biological background permit readers to explore a problem, understand assumptions, and the meaning of their results. The experiential components provide hands-on learning both in the lab and on the computer. As a beginning text in modeling, readers will learn to value the approach and apply competencies in other settings. Included case studies focus on building a model to solve a particular biological problem from concept and translation into a mathematical form, to validating the parameters, testing the quality of the model and finally interpreting the outcome in biological terms. The book also shows how particular mathematical approaches are adapted to a variety of problems at multiple biological scales. Finally, the labs bring the biological problems and the practical issues of collecting data to actually test the model and/or adapting the mathematics to the data that can be collected. Presents a single volume on mathematics and biological examples, with data and wet lab experiences suitable for non-experts Contains three real-world biological case studies and one wet lab for application of the mathematical models Includes R code templates throughout the text, which are also available through an online repository, along with the necessary data files to complete all projects and labs

Biological Growth and Spread

Biological Growth and Spread PDF Author: W. Jäger
Publisher: Springer Science & Business Media
ISBN: 3642618502
Category : Science
Languages : en
Pages : 521

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Book Description
These Proceedings have been assembled from papers presented at the Conference on Models of Biological Growth and Spread, held at the German Cancer Research Centre Heidelberg and at the Institute of Applied Mathematics of the University of Heidelberg, July 16-21, 1979. The main theme of the conference was the mathematical representation of biolog ical populations with an underlying spatial structure. An important feature of such populations is that they and/or their individual com ponents may interact with each other. Such interactions may be due to external disturbances, internal regulatory factors or a combination of both. Many biological phenomena and processes including embryogenesis, cell growth, chemotaxis, cell adhesion, carcinogenesis, and the spread of an epidemic or of an advantageous gene can be studied in this con text. Thus, problems of particular importance in medicine (human and veterinary), agriculture, ecology, etc. may be taken into consideration and a deeper insight gained by utilizing (more) realistic mathematical models. Since the intrinsic biological mechanisms may differ considerably from each other, a great variety of mathematical approaches, theories and techniques is required. The aims of the conference were (i) To provide an overview of the most important biological aspects. (ii) To survey and analyse possible stochastic and deterministic approaches. (iii) To encourage new research by bringing together mathematicians interested in problems of a biological nature and scientists actively engaged in developing mathematical models in biology.

Continuum Modeling in Mechanobiology

Continuum Modeling in Mechanobiology PDF Author: Larry A. Taber
Publisher: Springer Nature
ISBN: 3030432092
Category : Technology & Engineering
Languages : en
Pages : 545

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Book Description
This book examines key theoretical tools that are currently used to develop mathematical models as an aid in understanding the biological response of cells and tissues to mechanical stimuli. Problems in growth and remodeling, tissue and organ development, and functional adaptation are all covered. Chapters on tensor analysis and nonlinear elasticity provide the necessary background for understanding the engineering theories that are currently used to solve challenges in mechanobiology. This is an ideal book for biomechanical engineers who work on problems in mechanobiology and tissue engineering.

The Mathematics of Mechanobiology

The Mathematics of Mechanobiology PDF Author: Antonio DeSimone
Publisher: Springer Nature
ISBN: 3030451976
Category : Mathematics
Languages : en
Pages : 217

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Book Description
This book presents the state of the art in mathematical research on modelling the mechanics of biological systems – a science at the intersection between biology, mechanics and mathematics known as mechanobiology. The book gathers comprehensive surveys of the most significant areas of mechanobiology: cell motility and locomotion by shape control (Antonio DeSimone); models of cell motion and tissue growth (Benoît Perthame); numerical simulation of cardiac electromechanics (Alfio Quarteroni); and power-stroke-driven muscle contraction (Lev Truskinovsky). Each section is self-contained in terms of the biomechanical background, and the content is accessible to all readers with a basic understanding of differential equations and numerical analysis. The book disentangles the phenomenological complexity of the biomechanical problems, while at the same time addressing the mathematical complexity with invaluable clarity. The book is intended for a wide audience, in particular graduate students and applied mathematicians interested in entering this fascinating field.

On Growth and Form

On Growth and Form PDF Author: D'Arcy Wentworth Thompson
Publisher: DigiCat
ISBN:
Category : Fiction
Languages : en
Pages : 661

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Book Description
On Growth and Form is a scholarly work by D'Arcy Wentworth Thompson. Thompson was a Scottish biologist, mathematician, classics scholar and a pioneer of mathematical biology. Excerpt: "Of the chemistry of his day and generation, Kant declared that it was "a science, but not science,"—"eine Wissenschaft, aber nicht Wissenschaft"; for that the criterion of physical science lay in its relation to mathematics. And a hundred years later Du Bois Reymond, profound student of the many sciences on which physiology is based, recalled and reiterated the old saying, declaring that chemistry would only reach the rank of science, in the high and strict sense, when it should be found possible to explain chemical reactions in the light of their causal relation to the velocities, tensions and conditions of equilibrium of the component molecules; that, in short, the chemistry of the future must deal with molecular mechanics, by the methods and in the strict language of mathematics, as the astronomy of Newton and Laplace dealt with the stars in their courses. We know how great a step has been made towards this distant and once hopeless goal, as Kant defined it, since van't Hoff laid the firm foundations of a mathematical chemistry, and earned his proud epitaph, Physicam chemiae adiunxit."

Constitutive Modelling of Solid Continua

Constitutive Modelling of Solid Continua PDF Author: José Merodio
Publisher: Springer Nature
ISBN: 3030315479
Category : Science
Languages : en
Pages : 397

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Book Description
This volume consists of a collection of chapters by recognized experts to provide a comprehensive fundamental theoretical continuum treatment of constitutive laws used for modelling the mechanical and coupled-field properties of various types of solid materials. It covers the main types of solid material behaviour, including isotropic and anisotropic nonlinear elasticity, implicit theories, viscoelasticity, plasticity, electro- and magneto-mechanical interactions, growth, damage, thermomechanics, poroelasticity, composites and homogenization. The volume provides a general framework for research in a wide range of applications involving the deformation of solid materials. It will be of considerable benefit to both established and early career researchers concerned with fundamental theory in solid mechanics and its applications by collecting diverse material in a single volume. The readership ranges from beginning graduate students to senior researchers in academia and industry.

Multicellularity: Views from cellular signaling and mechanics

Multicellularity: Views from cellular signaling and mechanics PDF Author: Hiroaki Hirata
Publisher: Frontiers Media SA
ISBN: 283252026X
Category : Science
Languages : en
Pages : 139

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Book Description


Dynamic Models and Control of Biological Systems

Dynamic Models and Control of Biological Systems PDF Author: Vadrevu Sree Hari Rao
Publisher: Springer Science & Business Media
ISBN: 1441903593
Category : Science
Languages : en
Pages : 279

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Book Description
Mathematical Biology has grown at an astonishing rate and has established itself as a distinct discipline. Mathematical modeling is now being applied in every major discipline in the biological sciences. Though the field has become increasingly large and specialized, this book remains important as a text that introduces some of the exciting problems which arise in the biological sciences and gives some indication of the wide spectrum of questions that modeling can address.