Exploring the Clinical Implications of Brain-derived Neurotrophic Factor (BDNF). PDF Download
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Author: Dr.Hakim Saboowala
Publisher: Dr.Hakim Saboowala
ISBN:
Category : Medical
Languages : en
Pages : 64
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Book Description
Exploring the Clinical Implications of Brain-derived Neurotrophic Factor (BDNF). Brain-derived neurotrophic factor (BDNF) is one of the neurotrophic factors that support: · Differentiation, · Maturation, and · Survival of Neurons in the Nervous System and shows a Neuroprotective effect under adverse conditions, such as: · Glutamatergic stimulation, · Cerebral ischemia, · Hypoglycemia, and · Neurotoxicity. Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival and growth, serves as a neurotransmitter modulator, and participates in neuronal plasticity, which is essential for learning and memory. BDNF and insulin-like growth factor-1 have similar downstream signalling mechanisms incorporating both p-CAMK and MAPK that increase the expression of pro-survival genes. Brain-derived neurotrophic factor regulates glucose and energy metabolism and prevents exhaustion of β cells. Decreased levels of BDNF are associated with neurodegenerative diseases with neuronal loss. Thus, an attempt has been made in this E-Booklet to describe everything about BDNF elaborately along with several relevant ILLUSRATIONS for better understanding! …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)
Author: Dr.Hakim Saboowala
Publisher: Dr.Hakim Saboowala
ISBN:
Category : Medical
Languages : en
Pages : 64
Get Book
Book Description
Exploring the Clinical Implications of Brain-derived Neurotrophic Factor (BDNF). Brain-derived neurotrophic factor (BDNF) is one of the neurotrophic factors that support: · Differentiation, · Maturation, and · Survival of Neurons in the Nervous System and shows a Neuroprotective effect under adverse conditions, such as: · Glutamatergic stimulation, · Cerebral ischemia, · Hypoglycemia, and · Neurotoxicity. Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival and growth, serves as a neurotransmitter modulator, and participates in neuronal plasticity, which is essential for learning and memory. BDNF and insulin-like growth factor-1 have similar downstream signalling mechanisms incorporating both p-CAMK and MAPK that increase the expression of pro-survival genes. Brain-derived neurotrophic factor regulates glucose and energy metabolism and prevents exhaustion of β cells. Decreased levels of BDNF are associated with neurodegenerative diseases with neuronal loss. Thus, an attempt has been made in this E-Booklet to describe everything about BDNF elaborately along with several relevant ILLUSRATIONS for better understanding! …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)
Author: Markus Christen
Publisher: Frontiers Media SA
ISBN: 2889453731
Category :
Languages : en
Pages : 84
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Book Description
Neuromodulation is among the fastest-growing areas of medicine, involving many diverse specialties and affecting hundreds of thousands of patients with numerous disorders worldwide. It can briefly be described as the science of how electrical, chemical, and mechanical interventions can modulate the nervous system function. A prominent example of neuromodulation is deep brain stimulation (DBS), an intervention that reflects a fundamental shift in the understanding of neurological and psychiatric diseases: namely as resulting from a dysfunctional activity pattern in a defined neuronal network that can be normalized by targeted stimulation. The application of DBS has grown remarkably and more than 130,000 patients worldwide have obtained a DBS intervention in the past 30 years—most of them for treating movement disorders. This Frontiers Research Topics provides an overview on the current discussion beyond basic research in DBS and other brain stimulation technologies. Researchers from various disciplines, who are working on broader clinical, ethical and social issues related to DBS and related neuromodulation technologies, have contributed to this research topic.
Author: Paul C. Lebby
Publisher: Oxford University Press
ISBN: 0199980993
Category : Psychology
Languages : en
Pages : 384
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Book Description
Brain Imaging: A Guide for Clinicians is designed to provide a foundation of information necessary to those wishing to integrate brain imaging into their practice, or to those that currently review brain scans but have minimal formal training in neuroimaging. The guide covers a range of topics important to those using brain imaging, such as the strengths and weaknesses of the many different techniques currently available, the factors that may influence the use of imaging data, common pitfalls or artifacts that may be misleading to the clinician, the most appropriate techniques to use given a specific clinical question or condition, how to interpret information presented on a brain image, and also how many pathological conditions appear on a variety of brain scanning techniques or sequences. This guide also provides detailed information regarding the identification of primary brain regions, anatomical structures, systems or pathways using both two-dimensional and three-dimensional imaging techniques. A brain atlas is included using both CT and MRI sequences to facilitate the reader's ability to identify most primary brain structures. A novel color-coded system is used throughout this guide to assist the reader in identifying slice locations and orientations. Images with green borders are displayed in the axial plane, with the slice location being shown on other orthogonal image planes by a green line. Similarly, images with a red border are displayed in the coronal plane and those with a blue border are displayed using a sagittal plane; red and blue reference lines are displayed on orthogonal slices to identify the slice location. The crosshairs formed by the color-coded reference lines optimize the reader's ability to identify primary anatomical structures or pathological markers and processes. This book is written in a manner to progress from a general description of the clinical use of brain images and the interpretation of brain scans, to more complex chapters involving neuroanatomy and imaging technology. Real life examples of clinical cases are integrated into all chapters of this guide. Brain Imaging: A Guide for Clinicians provides hundreds of images derived from traumatic and non-traumatic pathologies to provide the reader with examples of conditions most often seen in the clinic. PEARL-PERIL sections outline critical information for the clinician, along with many tables and charts designed to provide general information required when interpreting brain images.
Author: Marcus L. F. Janssen
Publisher: MDPI
ISBN: 3036503366
Category : Medical
Languages : en
Pages : 246
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Book Description
This book covers the current trends in clinical deep brain stimulation (DBS) research. This collection of papers from experts in the field provides state of the art knowledge and future perspectives in clinical DBS research. A range of topics involved in DBS is presented, ranging from high resolution imaging, electrophysiology and personalized medicine, in a broad range of brain disorders.
Author:
Publisher:
ISBN:
Category : Clinical medicine
Languages : en
Pages : 428
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Book Description
Author: David H. Barlow
Publisher: Oxford Library of Psychology
ISBN: 0199328714
Category : Psychology
Languages : en
Pages : 977
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Book Description
The exponential growth of clinical psychology since the late 1960s can be measured in part by the extensive literature on the subject. The field has come to be defined as much by its many topics as its many voices. The Oxford Handbook of Clinical Psychology synthesizes these decades of literature in one volume. In addition to core sections on topics such as training, assessment, diagnosis, and intervention, the handbook includes chapters devoted to emerging issues in the clinical field, including heath care reforms, cultural factors, and technological innovations and challenges. Each chapter offers a review of the most pertinent literature, outlining issues and identifying possibilities for future research.
Author: Tony Schneider
Publisher: Routledge
ISBN: 1135039119
Category : Psychology
Languages : en
Pages : 272
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Book Description
The clinician needs to make sense of many client experiences in the course of daily practice: do these experiences reflect the simple product of complex neurochemical activity, or do they represent another dynamic involving the subjective self? When research findings from the neurosciences are applied to clinical psychology, reductionist thinking is typically followed, but this creates problems for the clinical practitioner. In this book Tony Schneider draws together the three strands of philosophy, neuroscience, and psychology to explore the mind/body question as it affects the clinician. Taking a position more closely aligned with dualism, he argues for the utility in making distinctions between brain activity and ‘I’ – the subjective self – both in general psychological functioning and in psychopathology. Schneider considers traditional psychological topics contextualized by neuroscience research and the mind/body issue, as well as applying the ideas to various areas of clinical practice. Topics include: -the mind and body from the clinician’s perspective -fundamental aspects of the role and mechanics of the brain -the developing self and the relationship of ‘I’ with the self and with others -psychological functioning such as focus and memory, sleep and dreaming, and emotions and pain. The idea that ‘I am not my brain’ will resonate with many clinicians, and is systematically argued for in clinical literature and neuropsychology research here for the first time. The book will be of particular interest to psychologists, psychiatrists, counsellors and clinicians who wish to incorporate advances in neuroscience research in the conceptualization of their clinical work, and are looking for a working model that allows them to do so.
Author: Carol Kershaw
Publisher: W. W. Norton & Company
ISBN: 039370808X
Category : Psychology
Languages : en
Pages : 368
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Book Description
Helping clients control their own emotional reactivity. When conditions like anxiety and depression are experienced chronically, they condition neural pathways and shape a person’s perception of and response to life events. As these pathways are reinforced, unhealthy neural networks turn on with increasing ease in the presence of conscious and unconscious triggers. In this groundbreaking book, Kershaw and Wade present Brain Change Therapy (BCT), a therapeutic protocol in which clients learn to manage their emotions and behaviors, and thus reduce stress and control emotional reactivity. Drawing from the latest neuroscientific research as well as integrative principles from hypnosis, biofeedback, and cognitive therapy, BCT helps clients reach stable neurological and emotional states and thus shift perspectives, attitudes, beliefs, and personal narratives toward the positive. BCT starts with the working assumption that effective therapeutic change must inevitably include a repatterning of neural pathways, and employs “self-directed neuroplasticity” through the active practicing of focused attention. As an adjunct to these methods, it helps clients create new, empowering life experiences that can serve as the basis for new neural patterns. The book begins by laying the foundation for body–mind and brain–body interventions by exploring the basics of the brain: its anatomy, neuroanatomy, neurophysiology, electrochemical processes, and the rhythms of the brain and body and nature. The authors set forth a detailed protocol for neuroassessment and evaluation of new clients, with particular attention to assessing a client’s habitually activated emotional circuits, neural imprints, state flexibility, level of arousal, and any relevant neurobiological conditions. The authors go on to outline BCT and its interventions geared toward stress reduction and state change, or the capacity to shift the mind from one emotional state to another and to shift the brain from one neural pattern to another. Protocols for specific presenting problems, such as fear, anxiety, and life-threatening and chronic illnesses are outlined in detail. Because of the breadth of the BCT approach, it is effective in working with individuals who are interested in shifting and conditioning peak performance states of consciousness, and the authors offer protocols for helping their clients reach peak professional performance as well. With this book, clinicians will be able to empower their clients to find their way out of a wide range of debilitating mental states.
Author: Paul C. Lebby
Publisher: Oxford University Press
ISBN: 0199764670
Category : Medical
Languages : en
Pages : 433
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Book Description
This book is designed to provide a foundation of information necessary to those wishing to integrate brain imaging into their practice or who seek more training. Information is provided to assist the clinician in interpreting images, determining which scans to order, and how images should be used in the clinic.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 268
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Book Description
