Terminal Rage

Terminal Rage PDF Author: A.M. Khalifa
Publisher: Mavenhill
ISBN: 1940387000
Category : Fiction
Languages : en
Pages : 374

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Book Description
A ruthless terrorist with no past. A burned-out hostage negotiator with no future. And a clock ticking towards utter carnage unless a puzzle is solved: Who is he?

Terminal Rage

Terminal Rage PDF Author: A.M. Khalifa
Publisher: Mavenhill
ISBN: 1940387000
Category : Fiction
Languages : en
Pages : 374

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Book Description
A ruthless terrorist with no past. A burned-out hostage negotiator with no future. And a clock ticking towards utter carnage unless a puzzle is solved: Who is he?

On Rage

On Rage PDF Author: Germaine Greer
Publisher: Hachette Australia
ISBN: 0733644090
Category : Literary Collections
Languages : en
Pages : 104

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Book Description
ON RAGE is Germaine Greer's timeless essay about Aboriginal dispossession. With characteristic acuity and passion, Greer looks to the causes of rage and its consequences in Indigenous Australians. Originally published six months after Prime Minister Kevin Rudd's Apology to the Stolen Generations in 2008, this is an urgent and provocative examination of disempowerment by one of Australia's leading polemicists.

Biomedical Translational Research

Biomedical Translational Research PDF Author: R.C. Sobti
Publisher: Springer Nature
ISBN: 9811688451
Category : Medical
Languages : en
Pages : 493

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Book Description
The second volume of the Biomedical translational research discusses advancements in biomedical research for understanding the pathophysiology of various diseases towards improving diagnosis and treatment. It presents the integration of molecular-based technologies, clinical genomics, and medical informatics to improve diagnostic and treatment strategies. Further, the book reviews molecular genomics approaches for diagnosis and managing tuberculosis. It also covers the innovative strategies for cancer treatment through targeting metabolic pathways, tumor microenvironment, cancer stem cells, and immune cells. It also illuminates novel strategies for heart failure diagnosis and therapeutic approaches for the treatment of heart failure. It discusses improvements in translational research for discovery of new diagnostic tests, identifying novel biomarkers and drugable targets, and predicting optimal treatments based on understanding the underlying molecular basis of the disease. Lastly, it reviews the preclinical models of restenosis and their application and limitation in the evaluation of device-based interventional technologies for the treatment of coronary artery diseases.

Biomedical Science, Engineering and Technology

Biomedical Science, Engineering and Technology PDF Author: Dhanjoo N. Ghista
Publisher: BoD – Books on Demand
ISBN: 953307471X
Category : Medical
Languages : en
Pages : 906

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Book Description
This innovative book integrates the disciplines of biomedical science, biomedical engineering, biotechnology, physiological engineering, and hospital management technology. Herein, Biomedical science covers topics on disease pathways, models and treatment mechanisms, and the roles of red palm oil and phytomedicinal plants in reducing HIV and diabetes complications by enhancing antioxidant activity. Biomedical engineering coves topics of biomaterials (biodegradable polymers and magnetic nanomaterials), coronary stents, contact lenses, modelling of flows through tubes of varying cross-section, heart rate variability analysis of diabetic neuropathy, and EEG analysis in brain function assessment. Biotechnology covers the topics of hydrophobic interaction chromatography, protein scaffolds engineering, liposomes for construction of vaccines, induced pluripotent stem cells to fix genetic diseases by regenerative approaches, polymeric drug conjugates for improving the efficacy of anticancer drugs, and genetic modification of animals for agricultural use. Physiological engineering deals with mathematical modelling of physiological (cardiac, lung ventilation, glucose regulation) systems and formulation of indices for medical assessment (such as cardiac contractility, lung disease status, and diabetes risk). Finally, Hospital management science and technology involves the application of both biomedical engineering and industrial engineering for cost-effective operation of a hospital.

The Flyer Vault

The Flyer Vault PDF Author: Daniel Tate
Publisher: Dundurn
ISBN: 1459745442
Category : Music
Languages : en
Pages : 708

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Book Description
A visual tour de force showcasing Toronto’s vast concert history. “Not sure there’s ever been anything like this...The graphics are fascinating, the script is comprehensive. It’s staggering what’s been unleashed from the Vault.” — Gary Topp, promoter, half of the legendary duo the Garys “These pages will take you on a musical magical mystery tour of Toronto’s important place in concert history. Reading The Flyer Vault gives you a rush, just like the one you get when the house lights go down!” — Dan Kanter, multi-platinum-selling songwriter/producer “The Flyer Vault book helps bottle the lore, bringing me a little bit closer to my Toronto and its shows that have only grown in renown.” —Danko Jones, lead singer/guitarist of the rock trio Danko Jones Duke Ellington. Johnny Cash. David Bowie. Nirvana. Bob Marley. Wu-Tang Clan. Daft Punk. These are just some of the legendary names that played Toronto over the last century. Drawing from Daniel Tate’s extensive flyer collection, first archived on his Flyer Vault Instagram account, Tate and Rob Bowman have assembled a time capsule that captures a mesmerizing history of Toronto concert and club life, ?running the gamut of genres from vaudeville to rock, jazz to hip-hop, blues to electronica, and punk to country. The Flyer Vault: 150 Years of Toronto Concert History traces seminal live music moments in the city, including James Brown’s debut performance in the middle of a city-wide blackout, a then-unknown Jimi Hendrix backing up Wilson Pickett in 1966 — the year a new band from London named Led Zeppelin performed in Toronto six times — and the one and only show by the Notorious B.I.G., which almost caused a riot in the winter of 1995. Complementing the book’s flyers is the story of the music, highlighting such iconic venues as Massey Hall, the Concert Hall/Rock Pile/Club 888, and the BamBoo, alongside lesser-known but equally important clubs such as Industry Nightclub and the Edge.

Neurobiology of Alzheimer's Disease

Neurobiology of Alzheimer's Disease PDF Author: David Dawbarn
Publisher: Oxford University Press
ISBN: 0191034584
Category : Medical
Languages : en
Pages :

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Book Description
Alzheimer's disease is the most common form of dementia in the elderly; 450,000 people in the UK and 4.5 million people in the USA suffer with this disease. This 3rd edition of Neurobiology of Alzheimer's Disease gives a comprehensive and readable introduction to the disease, from molecular pathology to clinical practice. The book is intended for readers new to the field, and it also covers an extensive range of themes for those with in-depth knowledge of Alzheimer's disease. It will therefore act either as an introduction to the whole field of neurodegeneration or it will help experienced researchers to access the latest research in specialist topics. Each chapter is written by eminent scientists leading their fields in neuropathology, clinical practice and molecular neurobiology; appendices detail disease-associated proteins, their sequences, familial mutations and known structures. It will be essential reading for students interested in neurodegeneration and for researchers and clinicians, giving a coherent and cohesive approach to the whole area of research, and allowing access at different levels. For those in the pharmaceutical industry it describes the underlying molecular mechanisms involved in the pathogenesis of Alzheimer's disease and explains how current and potential therapeutics may work.

Studies on Renal Disorders

Studies on Renal Disorders PDF Author: Toshio Miyata
Publisher: Springer Science & Business Media
ISBN: 1607618575
Category : Science
Languages : en
Pages : 781

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Book Description
Conditions such as oxidative stress and hypoxia, which have a generalized impact on the oxygen metabolism, have been implicated in the genesis of kidney disease. This means that deepening our understanding of the pathobiology of oxygen metabolism in such diseases could be a fruitful path towards tangible clinical benefits. Studies in Renal Disorder collects reviews from leading researchers and clinical scientists working in exactly this field, providing an overview of the latest advances. The causal role of impaired oxygen metabolism in kidney disease has numerous clinical implications. It affects our understanding of the therapeutic benefits accruing from anti-hypertensive agents; the way we control hyperglycemia/hyperinsulinemia and hyperlipidemia; and our use of dietary approaches to the correction of obesity. The defensive mechanisms against oxidative stress, such as the Nrf2-Keap1 system, and hypoxia, such as the PHD-HIF system, have recently been explored in various cells, including kidney cells. These mechanisms include intracellular sensors for oxidative stress and hypoxia. This means that novel approaches targeting these sensors may offer clinical benefits in kidney disease in which oxidative stress and/or hypoxia is a final, common pathway.

Abingdon Old Testament Commentaries: Deuteronomy

Abingdon Old Testament Commentaries: Deuteronomy PDF Author: Prof. Walter Brueggemann
Publisher: Abingdon Press
ISBN: 142675051X
Category : Religion
Languages : en
Pages : 308

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Book Description
The Abingdon Old Testament Commentaries series offers compact, critical commentaries on all the books of the Old Testament. In addition to providing fundamental information on and insights into Old Testament writings, these commentaries exemplify the tasks and procedures of careful, critical exegesis so as to assist students of the Old Testament in coming to an informed engagement of the biblical texts themselves. These commentaries are written with special attention to the needs and interests of theology students, but they will also be useful for students in upper-level college or university settings, as well as for pastors and other church leaders. Each volume consists of four parts: -- an introduction that addresses the key issues raised by the writing; the literary genre, structure, and character of the writing; the occasional and situational context of the writing, including its wider social and historical context; and the theological and ethical significance of the writing within these several contexts-- a commentary on the text, organized by literary units, covering literary analysis, exegetical analysis, and theological and ethical analysis-- an annotated bibliography-- a brief subject index In this volume on Deuteronomy, Brueggemann shows the significance of the Book of Deuteronomy to the shape and substance of Israel's faith in the Old Testament. Deuteronomy gave classic articulation to the main themes characteristic of Judaism, and, derivatively, of Christianity. Brueggemann emphasizes that Deuteronomy is an expression of covenant theology, whereby YHWH and Israel are pledged to exclusive loyalty and fidelity to each other; YHWH is to assure the well-being of Israel, and Israel is to live in trust and obedience to YHWH. In examining the relationship of Israel to God, Brueggemann makes suggestions on how such covenant fidelity might be lived out by believers today. "Brueggemann's commentary on the Book of Deuteronomy provides an accessible exegetical and theological understanding of a crucial biblical text. The introduction presents Deuteronomy as an expression of the radical Yahwistic alternative to the political rhetoric and ideology of the Israelite monarchy in the eighth and seventh centuries. Each section consists of an introduction, exegesis, and theological and ethical analysis of the essential elements that form the core of Deuteronomy's message to the Israelite community. The choice between 'covenant' and 'idol' that forms the crux of the text's message is further interpreted in light of the concern for covenant faithfulness as expressed in the rest of the OT and in the proclamation of the NT. Brueggemann explores how this same choice is reflected in the political and ideological voices that address the community of faith today. This commentary introduces the Book of Deuteronomy to theological students, pastors and teachers and points to the relevance of its message for those who seek to bring the alternative biblical message into the current cultural conversation."--Beverly White Cushman, Calvin College, in Religious Studies Review, Volume 29 Number 3, July 2003.

The ON-nibus

The ON-nibus PDF Author: Various Various
Publisher: Melbourne Univ. Publishing
ISBN: 0522859526
Category : Social Science
Languages : en
Pages : 313

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Book Description
If you missed the first eight titles in MUP's acclaimed Little Books on Big Themes series, this is your chance to collect the whole set. Released in time for Christmas, the ON-nibus brings together eight 10,000-word essays on the big themes in life by leading Australian thinkers. Featured authors are Germaine Greer ('On Rage'), David Malouf ('On Experience'), Blanche d'Alpuget ('On Longing'), Barrie Kosky ('On Ecstasy'), Don Watson ('On Indignation'), Gay Bilson ('On Digestion'), Malcolm Knox ('On Obsession') and Anne Summers ('On Luck').

Arterial Aging and Age-Associated Arterial Diseases

Arterial Aging and Age-Associated Arterial Diseases PDF Author: Mingyi Wang
Publisher: Frontiers Media SA
ISBN: 2889456927
Category :
Languages : en
Pages : 188

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Book Description
The underlying mechanisms behind aging has long been a great scientific mystery that the biomedical research community has long studied. In developed nations, as the population grows older, increases in life expectancy is increasingly limited by our relatively poor control of chronic aging-associated diseases such as arterial aging. Among age-related conditions that negatively influence longevity. Growing evidence demonstrates that arterial aging is fundamentally caused by a proinflammatory process that begins at birth and results in detrimental effects that affects every organ system. Vascular aging is the leading risk factor for quintessential cardiovascular diseases such as hypertension and atherosclerosis. With aging, vascular walls develop a pro-inflammatory and stressed microenvironment characterized by both an upregulation of pro-inflammatory chemokines and cytokines as well as a down-regulation anti-inflammatory counterparts. This chronic imbalance in inflammatory regulatory networks is the key driver of changes at the cellular and molecular level that result in hypertensive and atherosclerotic arterial. Thus, an intervention of proinflammation may be a viable therapeutic intervention to reduce morbidity and mortality from cardiovascular diseases. In this eBook, we aim to supply an updated overview of the physiological and biochemical mechanisms that affect inflammation and vascular aging. We believe that this eBook will contribute to the understanding of the pathogenesis of many chronic or age-related diseases, as well as to their treatment with both current and new therapeutic approaches.