Sudden Death in Epilepsy: Basic and Translational Research

Sudden Death in Epilepsy: Basic and Translational Research PDF Author: Christopher M. DeGiorgio
Publisher: Frontiers Media SA
ISBN: 2889455947
Category :
Languages : en
Pages : 71

Get Book

Book Description
Sudden Death in Epilepsy (SUDEP) is a major cause of death in people with epilepsy, accounting for up to 17% of all deaths. Research interest is exploding, focusing on epidemiology, basic mechanisms, identification of risk factors, and biomarkers. New wearable technologies are approved or in development. These incorporate accelerometers and advanced heart rate detection, which are linked to smart phones. The advent of FDA approved detection devices now allows immediate intervention by family and loved ones. The next frontier for SUDEP remains effective prevention strategies, which will likely include new devices and pharmacologic interventions. This volume is organized into three sections: Basic and Physiologic Mechanisms; Clinical Risk Factors and Inventories; and Very Early Research into Pharmacologic Interventions. It is our hope that this eBook will inform clinicians of key advances in the field, and to foster and stimulate basic and translational research with one purpose: To prevent SUDEP in those at risk.

Sudden Death in Epilepsy: Basic and Translational Research

Sudden Death in Epilepsy: Basic and Translational Research PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

Get Book

Book Description
Sudden Death in Epilepsy (SUDEP) is a major cause of death in people with epilepsy, accounting for up to 17% of all deaths. Research interest is exploding, focusing on epidemiology, basic mechanisms, identification of risk factors, and biomarkers. New wearable technologies are approved or in development. These incorporate accelerometers and advanced heart rate detection, which are linked to smart phones. The advent of FDA approved detection devices now allows immediate intervention by family and loved ones. The next frontier for SUDEP remains effective prevention strategies, which will likely include new devices and pharmacologic interventions. This volume is organized into three sections: Basic and Physiologic Mechanisms; Clinical Risk Factors and Inventories; and Very Early Research into Pharmacologic Interventions. It is our hope that this eBook will inform clinicians of key advances in the field, and to foster and stimulate basic and translational research with one purpose: To prevent SUDEP in those at risk.

Sudden Unexpected Death in Epilepsy

Sudden Unexpected Death in Epilepsy PDF Author: Taylor & Francis Group
Publisher: CRC Press
ISBN: 9780367778446
Category :
Languages : en
Pages : 350

Get Book

Book Description
Sudden Unexpected Death in Epilepsy: Mechanisms and New Methods for Analyzing Risks builds on earlier works focusing on the clinical problem of sudden unexpected death in epilepsy (SUDEP). This book presents a methodology for identifying and classifying clusters of risks that lead to SUDEP. Developed over the last two years, the SUDEP Classification System and Risk Factor Cluster ID method will help to address gaps in our knowledge about the causes and possible prevention of this tragic complication. Exploring the interactions among the central and peripheral autonomic nervous systems and the cardiopulmonary systems, the book includes case studies of SUDEP, definite or probable, as well as near miss cases. It discusses how neurologists, emergency room physicians, and attending physicians can identify individuals at possible risk for SUDEP and lessen the chance of occurrence. Top medical professionals in the field detail the development of an international database of human cases and animal models of SUDEP and suggest how medical examiner and coroner offices can strengthen the database by providing information about incidences of SUDEP. In addition, the book describes related clinical and animal studies needed to classify risk factors for SUDEP victims. Understanding the risk factors and mechanisms underlying SUDEP will facilitate collaborative research in the laboratory, hospital, and clinic and lead to improved effectiveness of SUDEP prevention strategies.

Forebrain control of breathing and sudden death in epilepsy

Forebrain control of breathing and sudden death in epilepsy PDF Author: Steven Allen Crone
Publisher: Frontiers Media SA
ISBN: 2832526322
Category : Science
Languages : en
Pages : 124

Get Book

Book Description


Epilepsy Mortality: Leading Causes of Death, Co-morbidities, Cardiovascular Risk and Prevention

Epilepsy Mortality: Leading Causes of Death, Co-morbidities, Cardiovascular Risk and Prevention PDF Author: Christopher Michael DeGiorgio
Publisher: Frontiers Media SA
ISBN: 2889744612
Category : Medical
Languages : en
Pages : 86

Get Book

Book Description
We would like to acknowledge that Dr. Luke Allen , University College London, has acted as a coordinator and has contributed to the preparation of the proposal for this Research Topic.

Jasper's Basic Mechanisms of the Epilepsies

Jasper's Basic Mechanisms of the Epilepsies PDF Author: Jeffrey L. Noebels
Publisher: OUP USA
ISBN: 0199746540
Category : Medical
Languages : en
Pages : 1258

Get Book

Book Description
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Sudden Death in Epilepsy

Sudden Death in Epilepsy PDF Author: Claire M. Lathers
Publisher: CRC Press
ISBN: 1439802238
Category : Law
Languages : en
Pages : 1047

Get Book

Book Description
Though it is one of the most common causes of death in epilepsy patients, SUDEP is still infrequently and even reluctantly named on autopsy reports. This under-reporting equates to a lack of attention and earnest investigation into the cause, predisposition, and prevention of SUDEP. There is as yet little effort to establish an actionable strategy

Epileptic Seizure Disorders in Animal Models: Advances in Translational Approaches

Epileptic Seizure Disorders in Animal Models: Advances in Translational Approaches PDF Author: Evgenia Sitnikova
Publisher: Frontiers Media SA
ISBN: 2832548547
Category : Medical
Languages : en
Pages : 110

Get Book

Book Description


Seizures and Epilepsy

Seizures and Epilepsy PDF Author: Jerome Engel Jr
Publisher: Oxford University Press
ISBN: 019532854X
Category : Medical
Languages : en
Pages : 737

Get Book

Book Description
This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2014

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2014 PDF Author: United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher:
ISBN:
Category : Administrative agencies
Languages : en
Pages : 876

Get Book

Book Description