Statistical Causal Inferences and Their Applications in Public Health Research

Statistical Causal Inferences and Their Applications in Public Health Research PDF Author: Hua He
Publisher: Springer
ISBN: 3319412590
Category : Medical
Languages : en
Pages : 321

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Book Description
This book compiles and presents new developments in statistical causal inference. The accompanying data and computer programs are publicly available so readers may replicate the model development and data analysis presented in each chapter. In this way, methodology is taught so that readers may implement it directly. The book brings together experts engaged in causal inference research to present and discuss recent issues in causal inference methodological development. This is also a timely look at causal inference applied to scenarios that range from clinical trials to mediation and public health research more broadly. In an academic setting, this book will serve as a reference and guide to a course in causal inference at the graduate level (Master's or Doctorate). It is particularly relevant for students pursuing degrees in statistics, biostatistics, and computational biology. Researchers and data analysts in public health and biomedical research will also find this book to be an important reference.

Causal Inference

Causal Inference PDF Author: Miquel A. Hernan
Publisher: CRC Press
ISBN: 9781420076165
Category : Medical
Languages : en
Pages : 352

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Book Description
The application of causal inference methods is growing exponentially in fields that deal with observational data. Written by pioneers in the field, this practical book presents an authoritative yet accessible overview of the methods and applications of causal inference. With a wide range of detailed, worked examples using real epidemiologic data as well as software for replicating the analyses, the text provides a thorough introduction to the basics of the theory for non-time-varying treatments and the generalization to complex longitudinal data.

Statistical Models and Causal Inference

Statistical Models and Causal Inference PDF Author: David A. Freedman
Publisher: Cambridge University Press
ISBN: 0521195004
Category : Mathematics
Languages : en
Pages : 416

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Book Description
David A. Freedman presents a definitive synthesis of his approach to statistical modeling and causal inference in the social sciences.

Causal Inference in Statistics

Causal Inference in Statistics PDF Author: Judea Pearl
Publisher: John Wiley & Sons
ISBN: 1119186862
Category : Mathematics
Languages : en
Pages : 162

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Book Description
CAUSAL INFERENCE IN STATISTICS A Primer Causality is central to the understanding and use of data. Without an understanding of cause–effect relationships, we cannot use data to answer questions as basic as "Does this treatment harm or help patients?" But though hundreds of introductory texts are available on statistical methods of data analysis, until now, no beginner-level book has been written about the exploding arsenal of methods that can tease causal information from data. Causal Inference in Statistics fills that gap. Using simple examples and plain language, the book lays out how to define causal parameters; the assumptions necessary to estimate causal parameters in a variety of situations; how to express those assumptions mathematically; whether those assumptions have testable implications; how to predict the effects of interventions; and how to reason counterfactually. These are the foundational tools that any student of statistics needs to acquire in order to use statistical methods to answer causal questions of interest. This book is accessible to anyone with an interest in interpreting data, from undergraduates, professors, researchers, or to the interested layperson. Examples are drawn from a wide variety of fields, including medicine, public policy, and law; a brief introduction to probability and statistics is provided for the uninitiated; and each chapter comes with study questions to reinforce the readers understanding.

Causal Inference in Statistics, Social, and Biomedical Sciences

Causal Inference in Statistics, Social, and Biomedical Sciences PDF Author: Guido W. Imbens
Publisher: Cambridge University Press
ISBN: 0521885884
Category : Business & Economics
Languages : en
Pages : 647

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Book Description
This text presents statistical methods for studying causal effects and discusses how readers can assess such effects in simple randomized experiments.

Latent Variable Modeling and Applications to Causality

Latent Variable Modeling and Applications to Causality PDF Author: Maia Berkane
Publisher: Springer Science & Business Media
ISBN: 146121842X
Category : Mathematics
Languages : en
Pages : 285

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Book Description
This volume gathers refereed papers presented at the 1994 UCLA conference on "La tent Variable Modeling and Application to Causality. " The meeting was organized by the UCLA Interdivisional Program in Statistics with the purpose of bringing together a group of people who have done recent advanced work in this field. The papers in this volume are representative of a wide variety of disciplines in which the use of latent variable models is rapidly growing. The volume is divided into two broad sections. The first section covers Path Models and Causal Reasoning and the papers are innovations from contributors in disciplines not traditionally associated with behavioural sciences, (e. g. computer science with Judea Pearl and public health with James Robins). Also in this section are contri butions by Rod McDonald and Michael Sobel who have a more traditional approach to causal inference, generating from problems in behavioural sciences. The second section encompasses new approaches to questions of model selection with emphasis on factor analysis and time varying systems. Amemiya uses nonlinear factor analysis which has a higher order of complexity associated with the identifiability condi tions. Muthen studies longitudinal hierarchichal models with latent variables and treats the time vector as a variable rather than a level of hierarchy. Deleeuw extends exploratory factor analysis models by including time as a variable and allowing for discrete and ordi nal latent variables. Arminger looks at autoregressive structures and Bock treats factor analysis models for categorical data.

Fundamentals of Causal Inference

Fundamentals of Causal Inference PDF Author: Babette A. Brumback
Publisher: CRC Press
ISBN: 100047030X
Category : Mathematics
Languages : en
Pages : 248

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Book Description
One of the primary motivations for clinical trials and observational studies of humans is to infer cause and effect. Disentangling causation from confounding is of utmost importance. Fundamentals of Causal Inference explains and relates different methods of confounding adjustment in terms of potential outcomes and graphical models, including standardization, difference-in-differences estimation, the front-door method, instrumental variables estimation, and propensity score methods. It also covers effect-measure modification, precision variables, mediation analyses, and time-dependent confounding. Several real data examples, simulation studies, and analyses using R motivate the methods throughout. The book assumes familiarity with basic statistics and probability, regression, and R and is suitable for seniors or graduate students in statistics, biostatistics, and data science as well as PhD students in a wide variety of other disciplines, including epidemiology, pharmacy, the health sciences, education, and the social, economic, and behavioral sciences. Beginning with a brief history and a review of essential elements of probability and statistics, a unique feature of the book is its focus on real and simulated datasets with all binary variables to reduce complex methods down to their fundamentals. Calculus is not required, but a willingness to tackle mathematical notation, difficult concepts, and intricate logical arguments is essential. While many real data examples are included, the book also features the Double What-If Study, based on simulated data with known causal mechanisms, in the belief that the methods are best understood in circumstances where they are known to either succeed or fail. Datasets, R code, and solutions to odd-numbered exercises are available at www.routledge.com.

Oxford Textbook of Global Public Health

Oxford Textbook of Global Public Health PDF Author: Roger Detels
Publisher: Oxford University Press
ISBN: 019881013X
Category : Medical
Languages : en
Pages : 1717

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Book Description
Sixth edition of the hugely successful, internationally recognised textbook on global public health and epidemiology, with 3 volumes comprehensively covering the scope, methods, and practice of the discipline

Explanation in Causal Inference

Explanation in Causal Inference PDF Author: Tyler J. VanderWeele
Publisher: Oxford University Press, USA
ISBN: 0199325871
Category : Medical
Languages : en
Pages : 729

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Book Description
The book begins with a comprehensive introduction to mediation analysis, including chapters on concepts for mediation, regression-based methods, sensitivity analysis, time-to-event outcomes, methods for multiple mediators, methods for time-varying mediation and longitudinal data, and relations between mediation and other concepts involving intermediates such as surrogates, principal stratification, instrumental variables, and Mendelian randomization. The second part of the book concerns interaction or "moderation," including concepts for interaction, statistical interaction, confounding and interaction, mechanistic interaction, bias analysis for interaction, interaction in genetic studies, and power and sample-size calculation for interaction. The final part of the book provides comprehensive discussion about the relationships between mediation and interaction and unites these concepts within a single framework.

Targeted Learning

Targeted Learning PDF Author: Mark J. van der Laan
Publisher: Springer Science & Business Media
ISBN: 1441997822
Category : Mathematics
Languages : en
Pages : 628

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Book Description
The statistics profession is at a unique point in history. The need for valid statistical tools is greater than ever; data sets are massive, often measuring hundreds of thousands of measurements for a single subject. The field is ready to move towards clear objective benchmarks under which tools can be evaluated. Targeted learning allows (1) the full generalization and utilization of cross-validation as an estimator selection tool so that the subjective choices made by humans are now made by the machine, and (2) targeting the fitting of the probability distribution of the data toward the target parameter representing the scientific question of interest. This book is aimed at both statisticians and applied researchers interested in causal inference and general effect estimation for observational and experimental data. Part I is an accessible introduction to super learning and the targeted maximum likelihood estimator, including related concepts necessary to understand and apply these methods. Parts II-IX handle complex data structures and topics applied researchers will immediately recognize from their own research, including time-to-event outcomes, direct and indirect effects, positivity violations, case-control studies, censored data, longitudinal data, and genomic studies.