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Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher: IARC Monographs on the Evaluat
ISBN: 9789283213246
Category : Medical
Languages : en
Pages : 0
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Book Description
This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.
Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher: IARC Monographs on the Evaluat
ISBN: 9789283213246
Category : Medical
Languages : en
Pages : 0
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Book Description
This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.
Author: Suzanne H. Reuben
Publisher: DIANE Publishing
ISBN: 1437934218
Category : Health & Fitness
Languages : en
Pages : 240
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Book Description
Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.
Author: Patrick Sullivan
Publisher: Elsevier
ISBN: 008045772X
Category : Technology & Engineering
Languages : en
Pages : 384
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Book Description
In today’s chemically dependent society, environmental studies demonstrate that drinking water in developed countries contains numerous industrial chemicals, pesticides, pharmaceuticals and chemicals from water treatment processes. This poses a real threat. As a result of the ever-expanding list of chemical and biochemical products industry, current drinking water standards that serve to preserve our drinking water quality are grossly out of date. Environmental Science of Drinking Water demonstrates why we need to make a fundamental change in our approach toward protecting our drinking water. Factual and circumstantial evidence showing the failure of current drinking water standards to adequately protect human health is presented along with analysis of the extent of pollution in our water resources and drinking water. The authors also present detail of the currently available state-of-the-art technologies which, if fully employed, can move us toward a healthier future. * Addresses the international problems of outdated standards and the overwhelming onslaught of new contaminants. * Includes new monitoring data on non-regulated chemicals in water sources and drinking water. * Includes a summary of different bottled waters as well as consumer water purification technologies.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309175712
Category : Nature
Languages : en
Pages : 433
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Book Description
Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9789241545037
Category : Medical
Languages : en
Pages : 260
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Book Description
This volume describes the methods used in the surveillance of drinking water quality in the light of the special problems of small-community supplies, particularly in developing countries, and outlines the strategies necessary to ensure that surveillance is effective.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309224624
Category : Science
Languages : en
Pages : 276
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Book Description
Expanding water reuse-the use of treated wastewater for beneficial purposes including irrigation, industrial uses, and drinking water augmentation-could significantly increase the nation's total available water resources. Water Reuse presents a portfolio of treatment options available to mitigate water quality issues in reclaimed water along with new analysis suggesting that the risk of exposure to certain microbial and chemical contaminants from drinking reclaimed water does not appear to be any higher than the risk experienced in at least some current drinking water treatment systems, and may be orders of magnitude lower. This report recommends adjustments to the federal regulatory framework that could enhance public health protection for both planned and unplanned (or de facto) reuse and increase public confidence in water reuse.
Author: Deborah Blum
Publisher: Penguin
ISBN: 0143111124
Category : Political Science
Languages : en
Pages : 369
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Book Description
A New York Times Notable Book The inspiration for PBS's AMERICAN EXPERIENCE film The Poison Squad. From Pulitzer Prize winner and New York Times-bestselling author Deborah Blum, the dramatic true story of how food was made safe in the United States and the heroes, led by the inimitable Dr. Harvey Washington Wiley, who fought for change By the end of nineteenth century, food was dangerous. Lethal, even. "Milk" might contain formaldehyde, most often used to embalm corpses. Decaying meat was preserved with both salicylic acid, a pharmaceutical chemical, and borax, a compound first identified as a cleaning product. This was not by accident; food manufacturers had rushed to embrace the rise of industrial chemistry, and were knowingly selling harmful products. Unchecked by government regulation, basic safety, or even labelling requirements, they put profit before the health of their customers. By some estimates, in New York City alone, thousands of children were killed by "embalmed milk" every year. Citizens--activists, journalists, scientists, and women's groups--began agitating for change. But even as protective measures were enacted in Europe, American corporations blocked even modest regulations. Then, in 1883, Dr. Harvey Washington Wiley, a chemistry professor from Purdue University, was named chief chemist of the agriculture department, and the agency began methodically investigating food and drink fraud, even conducting shocking human tests on groups of young men who came to be known as, "The Poison Squad." Over the next thirty years, a titanic struggle took place, with the courageous and fascinating Dr. Wiley campaigning indefatigably for food safety and consumer protection. Together with a gallant cast, including the muckraking reporter Upton Sinclair, whose fiction revealed the horrific truth about the Chicago stockyards; Fannie Farmer, then the most famous cookbook author in the country; and Henry J. Heinz, one of the few food producers who actively advocated for pure food, Dr. Wiley changed history. When the landmark 1906 Food and Drug Act was finally passed, it was known across the land, as "Dr. Wiley's Law." Blum brings to life this timeless and hugely satisfying "David and Goliath" tale with righteous verve and style, driving home the moral imperative of confronting corporate greed and government corruption with a bracing clarity, which speaks resoundingly to the enormous social and political challenges we face today.
Author: Joseph V. Rodricks
Publisher: Cambridge University Press
ISBN: 9780521423311
Category : Medical
Languages : en
Pages : 286
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Book Description
Public concern regarding environmental pollution and chemicals present in foods, consumer products, and the work place are at an all time high. Whilst there is widespread awareness, confusion still reigns, aggravated by conflicting reports concerning carcinogens in food and drinking water, or about chemicals present in medicines and household products that may cause birth defects. The effort to understand how these pollutants and chemical products may harm human health is led by scientists in the disciplines of toxicology, epidemiology and risk assessment. The central purpose of this book is to describe how scientists come to understand the toxic properties of such chemicals and the health risks they may pose. Rather than attempting to expose governmental and corporate ignorance, negligence or corruption, this book explores the underlying scientific issues. It presents a practical and balanced clarification of the scientific basis for our concerns and uncertainties. It should serve to refocus the debate.
Author: Cornelis A. M. van Gestel
Publisher: CRC Press
ISBN: 9781439830093
Category : Medical
Languages : en
Pages : 320
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Book Description
In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology and classic human toxicology, Mixture Toxicity: Linking Approaches from Ecological and Human Toxicology incorporates extensive reviews of exposure to toxicants, toxicokinetics and toxicodynamics, toxicity of mixtures, and risk assessment. The book examines developments in both fields, compares and contrasts their current state of the art, and identifies where one field can learn from the other. Each chapter provides an essential overview of the state of the art in both human and ecotoxicological mixture risk assessment, focusing on the work published in the last fifteen years. The coverage progresses from exposure to risk assessment, at each step identifying the special complications typically raised by mixtures. Based on in-depth discussions among specialists representing different disciplines and approaches, the chapters each address: Exposure — how to quantify the amounts of chemicals that may enter the living organism Kinetics, dynamics, and metabolism — how the chemicals enter an organism, travel within the organism, how they are metabolized and reach the target site, and explain development of toxicity with time Toxicity — what are the chemicals’ detrimental effects on the organism Test design and complex mixture characterization — how chemicals interact, how to measure effects of mixtures, and how to identify responsible chemicals Risk assessment — how to assess for risks in humans and the environment An unusual combination of different points of view on exposure to and risk assessment of chemical mixtures, this book summarizes current knowledge on combined effects of toxicant mixtures, information that is generally only available in a very fragmented form as individual journal papers. It identifies possible crosslinks and includes recommendations for mutual developments that can improve the state of knowledge on mixture toxicity and ultimately lead to better and more integrated risk assessment.
Author: United States. Environmental Protection Agency. Office of Air and Radiation
Publisher:
ISBN:
Category : Air quality
Languages : en
Pages : 38
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Book Description
