Author: Peter J. H. Scott
Publisher: John Wiley & Sons
ISBN: 1118336704
Category : Science
Languages : en
Pages : 184
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Book Description
Integrates solid-phase organic synthesis with palladiumchemistry The Wiley Series on Solid-Phase Organic Syntheses keepsresearchers current with major accomplishments in solid-phaseorganic synthesis, providing full experimental details. Followingthe validated, tested, and proven experimental procedures, readerscan easily perform a broad range of complex syntheses needed fortheir own experiments and industrial applications. The series isconveniently organized into themed volumes according to thespecific type of synthesis. This second volume in the series focuses on palladium chemistryin solid-phase synthesis, exploring palladium catalysts andreactions, procedures for preparation and utilization, ligands, andlinker reactions. The first part of the volume offers acomprehensive overview of the field. Next, the chapters areorganized into three parts: Part Two: Palladium-Mediated Solid-Phase Organic Syntheses Part Three: Immobilized Catalysts and Ligands Part Four: Palladium-Mediated Multifunctional Cleavage Each chapter is written by one or more leading internationalexperts in palladium chemistry. Their contributions reflect athorough examination and review of the current literature as wellas their own first-hand laboratory experience. References at theend of each chapter serve as a gateway to the field'sliterature. The introduction of palladium-mediated, cross-coupling reactionsmore than thirty years ago revolutionized the science ofcarbon-carbon bond formation. It has now become a cornerstone oftoday's synthetic organic chemistry laboratory. With this volume,researchers in organic and medicinal chemistry have access to asingle resource that explains the fundamentals of palladiumchemistry in solid-phase synthesis and sets forth clear,step-by-step instructions for conducting their own syntheses.
Author: Anthony W. Czarnik
Publisher: John Wiley & Sons
ISBN: 0471458481
Category : Science
Languages : en
Pages : 177
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Book Description
The rapid expansion of combinatorial chemistry has renewed interest in solid-phase organic synthesis, a method that lends itself well to creating and screening large numbers of lead compounds. Solid-Phase Organic Syntheses, Volume 1 is the first volume in a series that will be updated annually, filling a gap in the existing chemical literature. Providing information previously unavailable from a single resource, this series is dedicated to providing researchers in the field with validated and tested methods for the solid-phase synthesis of interesting and biologically relevant molecules. Solid-phase methods will virtually always be invented for application in combinatorial organic synthesis. To meet these specific needs, Solid-Phase Organic Syntheses, Volume 1 focuses on a single type of synthetic transformation accomplished on solid support, and indicates how procedures are optimized to work with a structurally-wide variety of reagents. Written by recognized leaders in the field who review and test all chemical protocols before publication, organic transformations are organized by type of compound synthesized and reaction type. For the first time, experimental details for proven solid-phase synthetic molecules are collected in a single, invaluable resource. Solid-Phase Organic Syntheses, Volume 1 provides combinatorial chemists and researchers in organic chemistry and medicinal chemistry with the tools and descriptive protocols to achieve syntheses of desired compounds using a variety of solid supports and reagents.
Author: Patrick H. Toy
Publisher: John Wiley & Sons
ISBN: 0470599146
Category : Science
Languages : en
Pages : 560
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Book Description
Presents both the fundamental concepts and the most recent applications in solid-phase organic synthesis With its emphasis on basic concepts, Solid-Phase Organic Synthesis guides readers through all the steps needed to design and perform successful solid-phase organic syntheses. The authors focus on the fundamentals of heterogeneous supports in the synthesis of organic molecules, explaining the use of a solid material to facilitate organic synthesis. This comprehensive text not only presents the fundamentals, but also reviews the most recent research findings and applications, offering readers everything needed to conduct their own state-of-the-art science experiments. Featuring chapters written by leading researchers in the field, Solid-Phase Organic Synthesis is divided into two parts: Part One, Concepts and Strategies, discusses the linker groups used to attach the synthesis substrate to the solid support, colorimetric tests to identify the presence of functional groups, combinatorial synthesis, and diversity-oriented synthesis. Readers will discover how solid-phase synthesis is currently used to facilitate the discovery of new molecular functionality. The final chapter discusses how using a support can change or increase reaction selectivity. Part Two, Applications, presents examples of the solid-phase synthesis of various classes of organic molecules. Chapters explore general asymmetric synthesis on a support, strategies for heterocyclic synthesis, and synthesis of radioactive organic molecules, dyes, dendrimers, and oligosaccharides. Each chapter ends with a set of conclusions that underscore the key concepts and methods. References in each chapter enable readers to investigate any topic in greater depth. With its presentation of basic concepts as well as recent findings and applications, Solid-Phase Organic Synthesis is the ideal starting point for students and researchers in organic, medicinal, and combinatorial chemistry who want to take full advantage of current solid-phase synthesis techniques.
Author: Frederik C. Krebs
Publisher: Wiley
ISBN: 9781119952510
Category : Technology & Engineering
Languages : en
Pages : 360
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Book Description
Organic photovoltaics (OPV) are a new generation of solar cells with the potential to offer very short energy pay back times, mechanical flexibility and significantly lower production costs compared to traditional crystalline photovoltaic systems. A weakness of OPV is their comparative instability during operation and this is a critical area of research towards the successful development and commercialization of these 3rd generation solar cells. Covering both small molecule and polymer solar cells, Stability and Degradation of Organic and Polymer Solar Cells summarizes the state of the art understanding of stability and provides a detailed analysis of the mechanisms by which degradation occurs. Following an introductory chapter which compares different photovoltaic technologies, the book focuses on OPV degradation, discussing the origin and characterization of the instability and describing measures for extending the duration of operation. Topics covered include: Chemical and physical probes for studying degradation Imaging techniques Photochemical stability of OPV materials Degradation mechanisms Testing methods Barrier technology and applications Stability and Degradation of Organic and Polymer Solar Cells is an essential reference source for researchers in academia and industry, engineers and manufacturers working on OPV design, development and implementation.
Author: Anthony W. Czarnik
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Kevin Burgess
Publisher: John Wiley & Sons
ISBN: 0471458457
Category : Science
Languages : en
Pages : 294
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Book Description
Solid-Phase Organic Synthesis Edited by Kevin Burgess, Texas A & M University Efficient, high-throughput chemistry is now the focus of many research laboratories. Solid-phase organic syntheses are central to many of these combinatorial and parallel screening methodologies. Consequently, they have been a major scientific theme of the 1990s and promise to remain prominent for the first part of the new millennium. Indeed, a bewildering number of papers have entered the literature on this topic; some report minor modifications enabling transformation of solution-phase methods to a solid support, while others report major innovations. Solid-Phase Organic Synthesis collects, highlights, and critiques some of the key developments in the field. Leading practitioners explain different perspectives on diverse aspects of the area. Specific topics covered include: * Syntheses of guanidines * Palladium-catalyzed C-C bond forming reactions * S_nAr reactions for the formation of heterocycles * Sequence-specific arylalkyne oligomers * Resin-supported capture agents and other reagents * Synthesis on pins * Monitoring of supported reactions using IR * Solid-phase syntheses of natural product derivatives Of related interest . Combinatorial Chemistry and Molecular Diversity in Drug Discovery Eric M. Gordon and James F. Kerwin 1998 (0-471-15518-7) 544 pp. Combinatorial Chemistry Synthesis and Application Stephen R. Wilson and Anthony W. Czarnik 1997 (0-471-12687-X) 288 pp.
Author: Florencio Zaragoza Dörwald
Publisher: Wiley-VCH
ISBN:
Category : Science
Languages : en
Pages : 504
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Book Description
This is the number–one successful book on solid phase organic synthesis, now in its second, expanded edition. It offers the reader · a comprehensive overview of supports, spacers, and linkers · 15% more contents · everything there is to know about reactions and their applications · clear structure · numerous experimental guidelines for use in practice The ideal reference for newcomers and experts. "... I have no doubts that this text will be the benchmark for future publications on the subject, and a very hard act to follow for authors planning books of their own on this red hot topic." The Alchemist
Author: Sergio Carrà
Publisher: EOLSS Publications
ISBN: 1905839596
Category :
Languages : en
Pages : 516
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Book Description
Fundamentals of Chemistry theme in two volumes, is a component of Encyclopedia of Chemical Sciences, Engineering and Technology Resources in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. The Theme is organized into six different topics which represent the main scientific areas : History and Fundamentals of Chemistry; Chemical Experimentation and Instrumentation; Theoretical Approach to Chemistry; Chemical Thermodynamics; Rates of Chemical Reactions; Chemical Synthesis of Substances. These two volumes are aimed at the following five major target audiences: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers and NGOs
Author: Neeraj Kumar Mishra
Publisher: BoD – Books on Demand
ISBN: 9535103342
Category : Science
Languages : en
Pages : 170
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Book Description
Green chemistry is chemistry for the environment. It is really a philosophy and way of thinking that can help chemistry in research and production to develop more eco-friendly solutions. Green chemistry is considered an essential piece of a comprehensive program to protect human health and the environment. In its essence, green chemistry is a science-based non-regulatory and economically driven approach to achieving the goals of environmental protection and sustainable development. Combining the technological progress with environmental safety is one of the key challenges of the millennium. In this context, this book describes the environmentally benign approaches for the industries as well as chemical laboratories. In order to provide an insight into step change technologies, this book was edited by green organic chemists.
Author: Dr. Raman Singh
Publisher: Notion Press
ISBN:
Category : Technology & Engineering
Languages : en
Pages : 160
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Book Description
The current volume (Vol -II) of Contemporary Advances in Science & Technology focuses on Sustainable Chemistry and Technology. The volume is intended to serve as a resource for those with an interest in green chemistry and sustainable technologies, including postgraduate students, academic researchers, and industry professionals.
