Skin Cancer: Basic Science, Clinical Research and Treatment

Skin Cancer: Basic Science, Clinical Research and Treatment PDF Author: Claus Garbe
Publisher: Springer Science & Business Media
ISBN: 3642787711
Category : Medical
Languages : en
Pages : 535

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Book Description
In the past two decades, considerable interest in skin cancer has developed in the public and scientific communities. There may have been several reasons for this: - The rise in the global incidence of cutaneous cancers - New molecular biology techniques resulting in a better understanding of pathogenesis and improved diagnostic procedures - The advent of new pathological entities, e. g. , the endemic form of Kaposi's sarcoma - A constantly increasing range of therapeutic modalities, providing even more efficacious treatment and manage ment of skin cancers As N. E. Fusenig describes in the first chapter of this volume, basic research is only beginning to unravel the complex mechanism involved in cellular dedifferentiation and tumor progression. Progress is dearly needed, especially in dermato oncology, where the rise in the incidence of epithelial tumors has inflated the overall skin cancer incidence. The incidence of tumors of the skin exceeds that of all other neoplasias in humans, with recreational sun exposure being a suspected primary cause. Several studies on the effects of UV radiation have been included at the beginning of this volume. Even the role of long wavelength UV (UVA) has become a focus of research activities. The main concern is that the low carcinogenicity of UVA, in comparison to UVB, may be outweighed and exceeded in its effects by increased UV A exposure, e. g.

Skin Cancer: Basic Science, Clinical Research and Treatment

Skin Cancer: Basic Science, Clinical Research and Treatment PDF Author: Claus Garbe
Publisher: Springer Science & Business Media
ISBN: 3642787711
Category : Medical
Languages : en
Pages : 535

Get Book

Book Description
In the past two decades, considerable interest in skin cancer has developed in the public and scientific communities. There may have been several reasons for this: - The rise in the global incidence of cutaneous cancers - New molecular biology techniques resulting in a better understanding of pathogenesis and improved diagnostic procedures - The advent of new pathological entities, e. g. , the endemic form of Kaposi's sarcoma - A constantly increasing range of therapeutic modalities, providing even more efficacious treatment and manage ment of skin cancers As N. E. Fusenig describes in the first chapter of this volume, basic research is only beginning to unravel the complex mechanism involved in cellular dedifferentiation and tumor progression. Progress is dearly needed, especially in dermato oncology, where the rise in the incidence of epithelial tumors has inflated the overall skin cancer incidence. The incidence of tumors of the skin exceeds that of all other neoplasias in humans, with recreational sun exposure being a suspected primary cause. Several studies on the effects of UV radiation have been included at the beginning of this volume. Even the role of long wavelength UV (UVA) has become a focus of research activities. The main concern is that the low carcinogenicity of UVA, in comparison to UVB, may be outweighed and exceeded in its effects by increased UV A exposure, e. g.

Skin Cancer

Skin Cancer PDF Author: Claus Garbe
Publisher: Springer Verlag
ISBN: 9780387576305
Category : Medical
Languages : en
Pages : 440

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Book Description


The Surgeon General's Call to Action to Prevent Skin Cancer

The Surgeon General's Call to Action to Prevent Skin Cancer PDF Author: U.s. Department of Health and Human Services
Publisher: Createspace Independent Publishing Platform
ISBN: 9781502903853
Category : Medical
Languages : en
Pages : 112

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Book Description
Skin cancer is the most commonly diagnosed cancer in the United States, yet most cases are preventable. Every year in the United States, nearly 5 million people are treated for skin cancer, at an estimated cost of $8.1 billion. Melanoma, the most deadly form of skin cancer, causes nearly 9,000 deaths each year. Despite recent efforts to address risk factors, skin cancer rates continue to rise. While those with lighter skin are more susceptible, anyone can get skin cancer—and it can be serious, even deadly. Almost all of the conditions can be caused by unnecessary ultraviolet (UV) radiation exposure, usually from excessive time in the sun or from the use of indoor tanning devices. It is alarming that every year, nearly one out of every three young white women aged 16–25 engages in indoor tanning. It's important to shatter the myth that tanned skin is a sign of health. And a “base” tan is not a “safe” tan. Tanned skin is damaged skin. Understanding the risk of UV exposure is crucial to protecting ourselves and our loved ones. That is why “The Surgeon General's Call to Action to Prevent Skin Cancer” is important for all of us. It outlines action steps we can all take—as individuals, parents, educators, employers, policy makers, health care professionals, and communities—to reverse this alarming trend. As a nation, we can all do more to address skin cancer as a serious public health challenge. Everyone is urged to find out more about the risk of skin cancer—and what we all can do to prevent it.

Melanoma

Melanoma PDF Author: Howard L. Kaufman
Publisher: Springer
ISBN: 3319225391
Category : Medical
Languages : en
Pages : 416

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Book Description
Melanoma is one of the most types of cancer. When melanoma is detected at an early stage, treatment is highly successful, but outcomes can be poor when the disease is advanced. There has been significant progress in our understanding of the molecular biology, genetics, and immunology of melanoma over the past decade. This has been accompanied by rapid advances in therapeutic strategies for patients with melanoma. This book provides the clinician and the researcher with a broad understanding of the molecular and cellular pathogenesis of melanoma, explores the clinical characteristics and criteria for clinical and pathological staging of the disease, and provides an overview of current and evolving treatment strategies in the adjuvant, metastatic, and preventive settings. The treatment of special populations and rare variants of melanoma that often present particular clinical challenges is also covered. Authored by international experts in melanoma biology and clinical management, this volume concisely explains how to diagnose, treat, and prevent melanoma while reviewing advances in basic science and providing an overview of innovative approaches still under development.

Cutaneous Oncology

Cutaneous Oncology PDF Author: Stanley J. Miller
Publisher: Wiley-Blackwell
ISBN: 9780865425170
Category : Medical
Languages : en
Pages : 1024

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Book Description
This book was written to fill a perceived void in the current literature. Cutaneous Oncology is designed to focus on the nature and behaviour of cancers, standing at the junction of clinical medicine and basic science research to provide a whole picture of skin tumor biology to both clinicians and researchers. The book explains our clinical understanding of skin cancers in terms of their biological and molecular bases, and provides a framework of clinical settings in which to understand and appreciate the importance of individual facets of tumor biology.

Cutaneous Melanoma

Cutaneous Melanoma PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Melanoma

Melanoma PDF Author: Julia A. Newton Bishop
Publisher: John Wiley & Sons
ISBN: 1405149957
Category : Medical
Languages : en
Pages : 302

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Book Description
Melanoma is the most life threatening form of skin cancer, the incidence of which has been rising in the developing world due to its link with sun exposure. The increase in incidence had made it imperative that clinicians managing these patients keep up-to-date with the latest advances, allowing them to provide optimal treatment. As with the other Challenges books, Challenges in Melanoma assumes a certain level of knowledge and builds on this by discussing only areas of controversy and uncertainty in the basic science and clinical management of the disease. Authors aim to provide a balanced answer based on the scientific evidence, but ultimately draw some conclusions that will be of relevance to clinical practice. The content is organised into three sections: aetiology; diagnosis, screening and prevention; and management. All the chapters ask practical and pertinent questions. The book takes a global view of melanoma as a public health risk as well as looking at management issues.

Cancer

Cancer PDF Author: Craig A. Almeida
Publisher: John Wiley & Sons
ISBN: 1444357395
Category : Science
Languages : en
Pages : 364

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Book Description
“... Useful background information is displayed in blue boxes, and good use is made of numerous tables and diagrams... a useful book for the undergraduate medical or allied health professional...” –Oncology News, May/June 2010 This forward looking cancer biology book appeals to a wide ranging audience. Introductory chapters that provide the molecular, cellular, and genetic information needed to comprehend the material of the subsequent chapters bring unprepared students up to speed for the rest of the book and serve as a useful refresher for those with previous biology background. The second set of chapters focuses on the main cancers in terms of risk factors, diagnostic and treatment methods and relevant current research. The final section encompasses the immune system’s role in the prevention and development of cancer and the impact that the Human Genome Project will have on future approaches to cancer care. While best suited to non-majors cancer biology courses, the depth provided satisfies courses that combine both majors and non-majors. Also, and deliberately, the authors have incorporated relevant information on diagnosis and treatment options that lend appeal to the lay reader.

Mohs Micrographic Surgery

Mohs Micrographic Surgery PDF Author: Stephen N. Snow
Publisher: Univ of Wisconsin Press
ISBN: 9780299204709
Category : Mohs surgery
Languages : en
Pages : 464

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Book Description
Mohs Micrographic Surgery, an advanced treatment procedure for skin cancer, offers the highest potential for recovery--even if the skin cancer has been previously treated. This procedure is a state-of-the-art treatment in which the physician serves as surgeon, pathologist, and reconstructive surgeon. It relies on the accuracy of a microscope to trace and ensure removal of skin cancer down to its roots. This procedure allows dermatologists trained in Mohs Surgery to see beyond the visible disease and to precisely identify and remove the entire tumor, leaving healthy tissue unharmed. This procedure is most often used in treating two of the most common forms of skin cancer: basal cell carcinoma and squamous cell carcinoma. The cure rate for Mohs Micrographic Surgery is the highest of all treatments for skin cancer--up to 99 percent even if other forms of treatment have failed. This procedure, the most exact and precise method of tumor removal, minimizes the chance of regrowth and lessens the potential for scarring or disfigurement

Skin Cancer Overview

Skin Cancer Overview PDF Author: Yaguang Xi
Publisher: BoD – Books on Demand
ISBN: 9533077468
Category : Medical
Languages : en
Pages : 230

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Book Description
The book Skin Cancer Overview is divided into three sections to cover the most essential topics in skin cancer research: Etiology, Diagnosis and Treatment, and Prevention. Due to the complexity of skin cancer, this book attempts to not only provide the basic knowledge, but also present the novel trends of skin cancer research. All chapters were written by experts from around the world. It will be a good handbook for researchers with interests in skin cancer.