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Author: G. Barrie Wetherill
Publisher: Chapman & Hall
ISBN:
Category : Mathematics
Languages : en
Pages : 256
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Book Description
The sequential probability ratin test; Sequential tests between three hypotheses; Extensions to the SPRT; Some applications of Cox's theorem; Some methods leading to closed boundaries; Decision theory; Sequential estimation; Sequential estimation of points on regression functions; Sequential estimation of points on quantal response curves; Double sampling; Selection procedures.
Author: G. Barrie Wetherill
Publisher: Chapman & Hall
ISBN:
Category : Mathematics
Languages : en
Pages : 256
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Book Description
The sequential probability ratin test; Sequential tests between three hypotheses; Extensions to the SPRT; Some applications of Cox's theorem; Some methods leading to closed boundaries; Decision theory; Sequential estimation; Sequential estimation of points on regression functions; Sequential estimation of points on quantal response curves; Double sampling; Selection procedures.
Author: Nitis Mukhopadhyay
Publisher: CRC Press
ISBN: 9781420010022
Category : Mathematics
Languages : en
Pages : 504
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Book Description
Interactively Run Simulations and Experiment with Real or Simulated Data to Make Sequential Analysis Come Alive Taking an accessible, nonmathematical approach to this field, Sequential Methods and Their Applications illustrates the efficiency of sequential methodologies when dealing with contemporary statistical challenges in many areas. The book first explores fixed sample size, sequential probability ratio, and nonparametric tests. It then presents numerous multistage estimation methods for fixed-width confidence interval as well as minimum and bounded risk problems. The book also describes multistage fixed-size confidence region methodologies, selection methodologies, and Bayesian estimation. Through diverse applications, each chapter provides valuable approaches for performing statistical experiments and facilitating real data analysis. Functional in a variety of statistical problems, the authors’ interactive computer programs show how the methodologies discussed can be implemented in data analysis. Each chapter offers examples of input, output, and their interpretations. Available online, the programs provide the option to save some parts of an output so readers can revisit computer-generated data for further examination with exploratory data analysis. Through this book and its computer programs, readers will better understand the methods of sequential analysis and be able to use them in real-world settings.
Author: Jay Bartroff
Publisher: Springer Science & Business Media
ISBN: 1461461146
Category : Medical
Languages : en
Pages : 250
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Book Description
Sequential Experimentation in Clinical Trials: Design and Analysis is developed from decades of work in research groups, statistical pedagogy, and workshop participation. Different parts of the book can be used for short courses on clinical trials, translational medical research, and sequential experimentation. The authors have successfully used the book to teach innovative clinical trial designs and statistical methods for Statistics Ph.D. students at Stanford University. There are additional online supplements for the book that include chapter-specific exercises and information. Sequential Experimentation in Clinical Trials: Design and Analysis covers the much broader subject of sequential experimentation that includes group sequential and adaptive designs of Phase II and III clinical trials, which have attracted much attention in the past three decades. In particular, the broad scope of design and analysis problems in sequential experimentation clearly requires a wide range of statistical methods and models from nonlinear regression analysis, experimental design, dynamic programming, survival analysis, resampling, and likelihood and Bayesian inference. The background material in these building blocks is summarized in Chapter 2 and Chapter 3 and certain sections in Chapter 6 and Chapter 7. Besides group sequential tests and adaptive designs, the book also introduces sequential change-point detection methods in Chapter 5 in connection with pharmacovigilance and public health surveillance. Together with dynamic programming and approximate dynamic programming in Chapter 3, the book therefore covers all basic topics for a graduate course in sequential analysis designs.
Author: G.B. Wetherill
Publisher: Chapman and Hall/CRC
ISBN:
Category : Mathematics
Languages : en
Pages : 284
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Book Description
Work on sequential methods has recently developed considerably. This introductory text has been revised to include later developments and seeks to equip scientists with the knowledge and understanding of statistical methods used in the interpretation of quantitative data. As with the previous editions particular emphasis has been placed on methods which are of importance in practical applications.
Author: Christopher Jennison
Publisher: CRC Press
ISBN: 9781584888581
Category : Mathematics
Languages : en
Pages : 416
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Book Description
Group sequential methods answer the needs of clinical trial monitoring committees who must assess the data available at an interim analysis. These interim results may provide grounds for terminating the study-effectively reducing costs-or may benefit the general patient population by allowing early dissemination of its findings. Group sequential methods provide a means to balance the ethical and financial advantages of stopping a study early against the risk of an incorrect conclusion. Group Sequential Methods with Applications to Clinical Trials describes group sequential stopping rules designed to reduce average study length and control Type I and II error probabilities. The authors present one-sided and two-sided tests, introduce several families of group sequential tests, and explain how to choose the most appropriate test and interim analysis schedule. Their topics include placebo-controlled randomized trials, bio-equivalence testing, crossover and longitudinal studies, and linear and generalized linear models. Research in group sequential analysis has progressed rapidly over the past 20 years. Group Sequential Methods with Applications to Clinical Trials surveys and extends current methods for planning and conducting interim analyses. It provides straightforward descriptions of group sequential hypothesis tests in a form suited for direct application to a wide variety of clinical trials. Medical statisticians engaged in any investigations planned with interim analyses will find this book a useful and important tool.
Author: Arnaud Doucet
Publisher: Springer Science & Business Media
ISBN: 1475734379
Category : Mathematics
Languages : en
Pages : 590
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Book Description
Monte Carlo methods are revolutionizing the on-line analysis of data in many fileds. They have made it possible to solve numerically many complex, non-standard problems that were previously intractable. This book presents the first comprehensive treatment of these techniques.
Author: Ryszard Zieliński
Publisher:
ISBN:
Category : Mathematical statistics
Languages : en
Pages : 564
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Book Description
Author: Alexander Tartakovsky
Publisher: CRC Press
ISBN: 1439838216
Category : Mathematics
Languages : en
Pages : 600
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Book Description
Sequential Analysis: Hypothesis Testing and Changepoint Detection systematically develops the theory of sequential hypothesis testing and quickest changepoint detection. It also describes important applications in which theoretical results can be used efficiently. The book reviews recent accomplishments in hypothesis testing and changepoint detecti
Author: B.K. Ghosh
Publisher: CRC Press
ISBN: 9780824784089
Category : Mathematics
Languages : en
Pages : 672
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Book Description
Sequential analysis refers to the body of statistical theory and methods where the sample size may depend in a random manner on the accumulating data. A formal theory in which optimal tests are derived for simple statistical hypotheses in such a framework was developed by Abraham Wald in the early 1
Author: Nitis Mukhopadhyay
Publisher: CRC Press
ISBN: 9780824753955
Category : Mathematics
Languages : en
Pages : 498
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Book Description
A technically precise yet clear presentation of modern sequential methodologies having immediate applications to practical problems in the real world, Applied Sequential Methodologies communicates invaluable techniques for data mining, agricultural science, genetics, computer simulation, finance, clinical trials, sonar signal detection, randomization, multiple comparisons, psychology, tracking, surveillance, and numerous additional areas of application. Includes more than 500 references, 165 figures and tables, and over 25 pages of subject and author indexes. Applied Sequential Methodologies brings the crucial nature of sequential approaches up to speed with recent theoretical gains, demonstrating their utility for solving real-life problems associated with Change-point detection in multichannel and distributed systems Best component selection for multivariate distributions Multistate processes Approximations for moving sums of discrete random variables Interim and terminal analyses of clinical trials Adaptive designs for longitudinal clinical trials Slope estimation in measurement-error models Tests for randomization and target tracking Appropriate count of simulation runs Stock price models Orders of genes Size and power control in multiple comparisons Authored by 33 leading scientists, this volume will greatly benefit sequential analysts, data analysts, applied statisticians, biometricians, clinical trialists, and upper-level undergraduate and graduate students in these disciplines.
