Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters PDF full book. Access full book title Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters by M. Morad. Download full books in PDF and EPUB format.
Author: M. Morad
Publisher: Springer Science & Business Media
ISBN: 9401139903
Category : Medical
Languages : en
Pages : 586
Get Book
Book Description
Knowledge of cardiac ion channels and transporters has advanced remarkably in the last two decades with the development of patch-clamp and molecular biological techniques. This textbook offers a comprehensive overview of structures and functions of ion channels and transporters in the heart. Readers are first introduced to the molecular biology and electrophysiology of all the important ion channels. After discussing their developmental changes, the pharmacology and pathophysiology of clinically-relevant ion channels are reviewed. Molecular aspects of the cardiac excitation-contraction coupling and intracellular Ca2+ regulation by ion transporters are also described. The book will be useful to electrophysiologists, cardiac physiologists and pharmacologists, and molecular biologists interested in ion channels at all levels. For research specialists, the book will provide a perspective of the field. The book can be used as a reference source for working scientists in the fields of ion channels, biophysics, cardiac electrophysiology, and pharmacology. It is aimed at graduate and medical students, designed for use as a textbook for graduate and medical courses.
Author: M. Morad
Publisher: Springer Science & Business Media
ISBN: 9401139903
Category : Medical
Languages : en
Pages : 586
Get Book
Book Description
Knowledge of cardiac ion channels and transporters has advanced remarkably in the last two decades with the development of patch-clamp and molecular biological techniques. This textbook offers a comprehensive overview of structures and functions of ion channels and transporters in the heart. Readers are first introduced to the molecular biology and electrophysiology of all the important ion channels. After discussing their developmental changes, the pharmacology and pathophysiology of clinically-relevant ion channels are reviewed. Molecular aspects of the cardiac excitation-contraction coupling and intracellular Ca2+ regulation by ion transporters are also described. The book will be useful to electrophysiologists, cardiac physiologists and pharmacologists, and molecular biologists interested in ion channels at all levels. For research specialists, the book will provide a perspective of the field. The book can be used as a reference source for working scientists in the fields of ion channels, biophysics, cardiac electrophysiology, and pharmacology. It is aimed at graduate and medical students, designed for use as a textbook for graduate and medical courses.
Author: W.D. Dietrich
Publisher: Springer Science & Business Media
ISBN: 1461534526
Category : Science
Languages : en
Pages : 375
Get Book
Book Description
Neuroscientists from various disciplines have given extraordinary attention to the role of neurotransmitters in the field of neuronal injury. This volume summarizes the original oral and poster contributions which were presented at the symposium, "The Role of Neurotransmitters in Brain Injury," in Key West, Florida, between June 7-9, 1991. This symposium was the official Satellite of Brain-91, the Fifteenth International Symposium on Cerebral Blood Flow and Metabolism, held in Miami the previous week. The two principal goals of the Key West satellite meeting were to document recent progress and, more importantly, to explore future directions for investigative studies of the role of neurotransmitters in brain injury. To achieve these goals we assembled participants from diverse scientific fields and specialties who brought their collective expertise to discussions on the importance of neurotransmitters in neuronal and vascular injury following brain ischemia, trauma, and epilepsy. Their contributions are reflected in this volume. An important section of this volume is devoted to the role of glutamate and glutamatergic receptors in the development of ischemic neuronal damage. Topics covered include the mechanisms of glutamate and other excitatory amino acids, and the role of underlying injury-induced release different glutamatergic receptors in brain injury, including the NMDA and the non-NMDA receptors. The involvement of other neurotransmitters in the process of ischemic brain injury is well established.
Author: Megh R. Goyal
Publisher: CRC Press
ISBN: 1000008363
Category : Technology & Engineering
Languages : en
Pages : 239
Get Book
Book Description
This informative volume provides new insights with scientific evidence on the uses of medicinal plants in the treatment of certain diseases. It reviews various therapies with herbal phytoconstituents for certain types of disorders, modes of action, and pharmacological screening. It focuses on potential benefits of herbal extracts and bioactive compounds for human health care, provides a comparative phytoconstituent analysis of selected medicinal plants using GCMS/FTIR techniques, and discusses the role of herbal medicines in female genital infections. It goes on to look at the health-boosting properties of cabbage and the functional properties of milk yam (Ipomoea digitata L.).
Author: Gregory Nagy
Publisher: Routledge
ISBN: 1136065865
Category : Literary Criticism
Languages : en
Pages : 350
Get Book
Book Description
First published in 2002. Routledge is an imprint of Taylor & Francis, an informa company.
Author: Matt Kaplan
Publisher: Hachette UK
ISBN: 1472101162
Category : Science
Languages : en
Pages : 256
Get Book
Book Description
Modern audiences do not find dragons frightening. Fascinating as mythical creatures, yes, but terrifying, no. Yet, present them with a story about a virus that can kill a healthy adult in hours and they will have nightmares for weeks. The difference between the two is believability. Monsters are at their most frightening when they carry characteristics that tie them to the real world in some way. Preposterous as they might seem today, dragons were no different in ancient times. Humans long ago stumbled upon skeletons that had sharp teeth and talon-like claws. These fossils were real and some were frighteningly large. Those who looked at them could only guess at how dangerous the animals that they belonged to must have been. From such interactions, dragons were born. Yet, in spite of ample physical evidence that dragons existed, none were ever seen in the flesh. Dragon bones were ultimately proven to be the bones of huge predatory dinosaurs like Tyrannosaurus Rex, but before the mystery was solved, they were the makings of frightening beasts that managed to evade human sight by lurking deep within the shadows of the wild. The Science of Monsters will explore monsters that have haunted humanity throughout the ages, from Medusa to sea serpents, giants, and vampires. In each chapter Kaplan uses scientific principles, current research, and his thorough knowledge of the natural world to explain why specific monsters came to be and what it was about them that was so terrifying to the people who brought them to life.
Author: United States. Congress. Senate. Select Committee on Small Business. Subcommittee on Monopoly
Publisher:
ISBN:
Category : Antitrust law
Languages : en
Pages : 496
Get Book
Book Description
Author: Anne C. Richard
Publisher: Center for Transatlantic Relations Sais
ISBN:
Category : Nature
Languages : en
Pages : 104
Get Book
Book Description
After Hurricane Katrina hit the Gulf Coast of the United States on the morning of August 29, 2005, offers of help from other countries poured in on the US Government. Not used to being a recipient of foreign aid, the federal government replied slowly and with mixed signals. This monograph tells the story of these foreign contributions and the U.S. response. Lessons from this experience suggest that plans for a vetting mechanism should be drawn up now so that it is widely understood before the next large-scale crisis hits. In addition, the international community should adopt a uniform list of goods for stockpiling and use in a crisis, and should meet to reach agreement on the best ways to respond to crises. Effective crisis response is an important part of national security.
Author: Fernando Cervero
Publisher: Newnes
ISBN: 0444519017
Category : Medical
Languages : en
Pages : 954
Get Book
Book Description
This volume provides a comprehensive accounting of pain and its relation to neurology. It is dedicated entirely to the mechanisms and clinical aspects of the subject, and provides a wealth of information on the latest neurobiological and clinical data surrounding the topic. From discussions of the physiology and pathology of the pain pathways from signaling, via spinal cord and supraspinal processing to endogenous pain modulation, users will gain an invaluable reference that provides a new understanding of pain related topics, including cytokines, sex differences, and the autonomic nervous system. Practicing clinicians, internists, surgeons, and those in the fields of psychiatry and gerontology will gain a greater understanding of this challenging topic with chapters that deal extensively with peripheral and central pain conditions, including specific disorders such as fibromyalgia, whiplash, psychiatric diseases, dementia, and even cancer. In addition, treatments for neuropathic pain are also thoroughly presented and discussed. * A comprehensive guide to the topic of pain and its relation to neurology * Invaluable information on specific topics of interest, including discussions of pain and its implications for related diseases and conditions such as fibromyalgia, whiplash, and even psychiatric disorders * Treatment protocols for neuropathic pain and patient care
Author: Ralph Wynn
Publisher: Springer Science & Business Media
ISBN: 1468422715
Category : Nature
Languages : en
Pages : 759
Get Book
Book Description
In the decade following the publication of the first edition of Cellular Biology of the Uterus, advances in this field have been so rapid as to require not merely a revision of the earlier text but an essentially new volume. Even the title of the book has been changed, to Biology of the Uterus, to reflect the incorporation of more material based on classical anatomy and physiology. This histological and embryological information provides a necessary, though often lacking, background for the protein chemist and molecular biologist, and a bridge between biochemistry and biophysics, on the one hand, and clinical medicine, on the other. Thus, major practical problems in human reproduction, such as the mode of action of contraceptive agents and the cause of the initiation of labor, may be approached on a firm scientific footing. This text deals primarily with the biology of the uterus itself (comparative and human) rather than with placentation or pregnancy, and as such is a synthesis of data derived from many techniques, conventional and modern. Inasmuch as it is clearly beyond the competence of anyone scientist to prepare such a text on the basis of personal knowledge and experience, the aid of distinguished biologists from this country and abroad was enlisted. All of these authors, acknowledged experts in their respective fields, agreed to extensive revision of their chapters or preparation of entirely new contributions.
Author: Douglas P. Zipes
Publisher: Elsevier Health Sciences
ISBN: 143772762X
Category : Medical
Languages : en
Pages : 1183
Get Book
Book Description
Cardiac Electrophysiology: From Cell to Bedside defines the entire state of current scientific and clinical knowledge in this subspecialty. In response to the many major recent developments in the field, Drs. Zipes and Jalife have completely updated this modern classic, making the 5th Edition the most significant revision yet. From our latest understanding of ion channels, molecular genetics, and cardiac electrical activity through newly recognized syndromes, unique needs of special patient populations, and new diagnostic and therapeutic options, you'll find all the state-of-the-art guidance you need to make informed, effective clinical decisions. What's more, a significantly restructured organization, a new full-color layout, and full-text online access make reference easier than ever. Integrates the latest scientific understanding of arrhythmias with the newest clinical applications, giving you an informed basis for choosing the right treatment and management options for each patient. Synthesizes the knowledge of preeminent authorities in cardiology, physiology, pharmacology, pediatrics, biophysics, pathology, cardiothoracic surgery, and biomedical engineering from around the world, giving you a well-rounded, expert grasp of every issue that affects your patient management. Contains 24 new chapters (listed below) as well as exhaustive updates throughout, to keep you current with new scientific knowledge, newly discovered arrhythmia syndromes, and new diagnostic and therapeutic techniques. Developmental Regulation of Cardiac Ion Channels Neural Mechanisms of Initiating and Maintaining Arrhythmias Single Nucleotide Polymorphisms and Acquired Cardiac Arrhythmias Inheritable Sodium Channel Diseases Inheritable Potassium Channel Diseases Inheritable Diseases of Intracellular Calcium Regulation Morphological Correlates of Atrial Arrhythmias Andersen-Tawil Syndrome Timothy Syndrome Progressive Cardiac Conduction Disease Sudden Infant Death Syndrome Arrhythmias in Patients with Neurologic Disorders Autonomic Testing Cardiac Resynchronization Therapy Energy Sources for Catheter Ablation Linear Lesions to Ablate Atrial Fibrillation Catheter Ablation of Ventricular Arrhythmias in Patients with Structural Heart Disease Catheter Ablation of Ventricular Arrhythmias in Patients without Structural Heart Disease Catheter Ablation in Patients with Congenital Heart Disease Features a completely new section on "Arrhythmias in Special Populations" that explores arrhythmias in athletes ... gender differences in arrhythmias ... arrhythmias in pediatric patients ... and sleep-disordered breathing and arrhythmias. Offers an attractive new full-color design featuring color photos, tables, flow charts, ECGs, and more, making clinically actionable information easy to find and absorb at a glance. Includes full-text online access via Expert Consult, making reference easier for busy practitioners.
