Regulation of Gene Expression and Brain Function PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Regulation of Gene Expression and Brain Function PDF full book. Access full book title Regulation of Gene Expression and Brain Function by Paul J. Harrison. Download full books in PDF and EPUB format.
Author: Paul J. Harrison
Publisher: Springer Science & Business Media
ISBN: 3642784585
Category : Science
Languages : en
Pages : 71
Get Book
Book Description
Gene expression converts the information coded by our genes into proteins. These determine the structure and function of an organ such as the brain. Itis therefore an essential process, linking molecular genetics with neurochemistry and behavioral neuroscience. This volume presents a didactic approach to the understanding of the basic processes of gene expression and their involvement in certain brain diseases, such asAlzheimer's disease and schizophrenia. Generously illustrated, the contributions provide a valuable outline of this key aspect of molecular neurobiology and clinical neuroscience.
Author: Paul J. Harrison
Publisher: Springer Science & Business Media
ISBN: 3642784585
Category : Science
Languages : en
Pages : 71
Get Book
Book Description
Gene expression converts the information coded by our genes into proteins. These determine the structure and function of an organ such as the brain. Itis therefore an essential process, linking molecular genetics with neurochemistry and behavioral neuroscience. This volume presents a didactic approach to the understanding of the basic processes of gene expression and their involvement in certain brain diseases, such asAlzheimer's disease and schizophrenia. Generously illustrated, the contributions provide a valuable outline of this key aspect of molecular neurobiology and clinical neuroscience.
Author: Paul Buckley
Publisher: Springer
ISBN: 9783642784590
Category : Science
Languages : en
Pages : 64
Get Book
Book Description
Gene expression converts the information coded by our genes into proteins. These determine the structure and function of an organ such as the brain. Itis therefore an essential process, linking molecular genetics with neurochemistry and behavioral neuroscience. This volume presents a didactic approach to the understanding of the basic processes of gene expression and their involvement in certain brain diseases, such asAlzheimer's disease and schizophrenia. Generously illustrated, the contributions provide a valuable outline of this key aspect of molecular neurobiology and clinical neuroscience.
Author: Timothy W Bredy
Publisher: Academic Press
ISBN: 0128017813
Category : Science
Languages : en
Pages : 180
Get Book
Book Description
DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states. Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease. Provides a comprehensive overview of the many facets of DNA modifications Discusses the impact of this dynamic epigenetic mechanism across brain development and lifespan at behavioral, cognitive, molecular and genetic levels Contains contributions by influential leaders in the field Edited by a Neuroscientist to further promote synthesis between epigenetics, neuroscience, and clinical relevance
Author:
Publisher: Academic Press
ISBN: 0128137975
Category : Medical
Languages : en
Pages : 378
Get Book
Book Description
Chromatin Signaling and Neurological Disorders, Volume Seven, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship between chromatin signaling and neurological disorders, but they'll also discover approaches to better interpret and employ new diagnostic studies and epigenetic-based therapies. A diverse range of chapters from international experts speaks to the basis of chromatin and epigenetic signaling pathways and specific chromatin signaling factors that regulate a range of diseases. In addition to the basic science of chromatin signaling factors, each disease-specific chapter speaks to the translational or clinical significance of recent findings, along with important implications for the development of epigenetics-based therapeutics. Common themes of translational significance are also identified across disease types, as well as the future potential of chromatin signaling research. Examines specific chromatin signaling factors that regulate spinal muscular atrophy, ulbospinal muscular atrophy, amyotrophic lateral sclerosis, Parkinson's disease, Huntington's disease, multiple sclerosis, Angelman syndrome, Rader-Willi syndrome, and more Contains chapter contributions from international experts who speak to the clinical significance of recent findings and the implications for the development of epigenetics-based therapeutics Provides researchers, students and clinicians with approaches to better interpret and employ new diagnostic studies for treating neurological disorders
Author: Gerald Thiel
Publisher: John Wiley & Sons
ISBN: 3527607366
Category : Science
Languages : en
Pages : 505
Get Book
Book Description
This first book to cover neural development, neuronal survival and function on the genetic level outlines promising approaches for novel therapeutic strategies in fighting neurodegenerative disorders, such as Alzheimer's disease. Focusing on transcription factors, the text is clearly divided into three sections devoted to transcriptional control of neural development, brain function and transcriptional dysregulation induced neurological diseases. With a chapter written by Nobel laureate Eric Kandel, this is essential reading for neurobiologists, geneticists, biochemists, cell biologists, neurochemists and molecular biologists.
Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0
Get Book
Book Description
Author:
Publisher: Elsevier
ISBN: 0444538852
Category : Science
Languages : en
Pages : 376
Get Book
Book Description
How does the genome, interacting with the multi-faceted environment, translate into the development by which the human brain achieves its astonishing, adaptive array of cognitive and behavioral capacities? Why and how does this process sometimes lead to neurodevelopmental disorders with a major, lifelong personal and social impact? This volume of Progress in Brain Research links findings on the structural development of the human brain, the expression of genes in behavioral and cognitive phenotypes, environmental effects on brain development, and developmental processes in perception, action, attention, cognitive control, social cognition, and language, in an attempt to answer these questions. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Author: Luke B. Hesson
Publisher: Springer Nature
ISBN: 9811389586
Category : Medical
Languages : en
Pages : 265
Get Book
Book Description
In genetic pathology, epigenetic testing is rare and under utilised. In this book, we introduce epigenetics to a non-expert scientific audience and describe current and future clinical utility of epigenetic testing. By focussing on epigenetics in human disease this book will guide professionals (scientists and clinicians) to understand how epigenetics is relevant in a clinical context, and to implement epigenetic testing in diagnostic laboratories. The book begins with a historical perspective of genetics and epigenetics and describes the work of pioneers who have helped shape these fields. The various mechanisms by which epigenetics can regulate the function of the genome is described. These include DNA methylation, histone modifications, histone variants, nucleosome positioning, cis-regulatory elements, non-coding RNAs and the three-dimensional organisation of chromatin in the nucleus. These are discussed in the context of embryological development, cancer and imprinting disorders, and include examples of epigenetic changes that can be used in diagnosis, prediction of therapeutic response, prognostication or disease monitoring. Finally, for those wishing to implement epigenetic testing in a diagnostic setting, the book includes a case study that illustrates the clinical utility of epigenetic testing.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309072964
Category : Social Science
Languages : en
Pages : 225
Get Book
Book Description
New Horizons in Health discusses how the National Institutes of Health (NIH) can integrate research in the social, behavioral, and biomedical sciences to better understand the causes of disease as well as interventions that promote health. It outlines a set of research priorities for consideration by the Office of Behavioral and Social Sciences Research (OBSSR), with particular attention to research that can support and complement the work of the National Institutes of Health. By addressing the range of interactions among social settings, behavioral patterns, and important health concerns, it highlights areas of scientific opportunity where significant investment is most likely to improve nationalâ€"and globalâ€"health outcomes. These opportunities will apply the knowledge and methods of the behavioral and social sciences to contemporary health needs, and give attention to the chief health concerns of the general public.
Author: H. Philip Zeigler
Publisher: Cambridge University Press
ISBN: 9781107411579
Category : Science
Languages : en
Pages : 0
Get Book
Book Description
Speech has long been thought of as a uniquely defining characteristic of humans. Yet song birds, like humans, communicate using learned signals (song, speech) that are acquired from their parents by a process of vocal imitation. Both song and speech begin as amorphous vocalizations (subsong, babble) that are gradually transformed into an individualized version of the parents' speech, including dialects. With contributions from both the founding forefathers and younger researchers of this field, this book provides a comprehensive summary of birdsong neurobiology, and identifies the common brain mechanisms underlying this achievement in both birds and humans. Written primarily for advanced graduates and researchers, there is an introductory overview covering song learning, the parallels between language and birdsong and the relationship between the brains of birds and mammals; subsequent sections deal with producing, processing, learning and recognizing song, as well as with hormonal and genomic mechanisms.
