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Author: Amir Mirmiran
Publisher: Transportation Research Board
ISBN: 0309087856
Category : Medical
Languages : en
Pages : 102
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Book Description
The global response to COVID-19 has demonstrated the importance of vigilance and preparedness for infectious diseases, particularly influenza. There is a need for more effective influenza vaccines and modern manufacturing technologies that are adaptable and scalable to meet demand during a pandemic. The rapid development of COVID-19 vaccines has demonstrated what is possible with extensive data sharing, researchers who have the necessary resources and novel technologies to conduct and apply their research, rolling review by regulators, and public-private partnerships. As demonstrated throughout the response to COVID-19, the process of research and development of novel vaccines can be significantly optimized when stakeholders are provided with the resources and technologies needed to support their response. Vaccine Research and Development to Advance Pandemic and Seasonal Influenza Preparedness and Response focuses on how to leverage the knowledge gained from the COVID-19 pandemic to optimize vaccine research and development (R&D) to support the prevention and control of seasonal and pandemic influenza. The committee's findings address four dimensions of vaccine R&D: (1) basic and translational science, (2) clinical science, (3) manufacturing science, and (4) regulatory science.
Author: Amir Mirmiran
Publisher: Transportation Research Board
ISBN: 0309087856
Category : Medical
Languages : en
Pages : 102
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Book Description
The global response to COVID-19 has demonstrated the importance of vigilance and preparedness for infectious diseases, particularly influenza. There is a need for more effective influenza vaccines and modern manufacturing technologies that are adaptable and scalable to meet demand during a pandemic. The rapid development of COVID-19 vaccines has demonstrated what is possible with extensive data sharing, researchers who have the necessary resources and novel technologies to conduct and apply their research, rolling review by regulators, and public-private partnerships. As demonstrated throughout the response to COVID-19, the process of research and development of novel vaccines can be significantly optimized when stakeholders are provided with the resources and technologies needed to support their response. Vaccine Research and Development to Advance Pandemic and Seasonal Influenza Preparedness and Response focuses on how to leverage the knowledge gained from the COVID-19 pandemic to optimize vaccine research and development (R&D) to support the prevention and control of seasonal and pandemic influenza. The committee's findings address four dimensions of vaccine R&D: (1) basic and translational science, (2) clinical science, (3) manufacturing science, and (4) regulatory science.
Author: Kishore V. Pochiraju
Publisher: Springer Science & Business Media
ISBN: 1441993088
Category : Technology & Engineering
Languages : en
Pages : 681
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Book Description
Long-Term Durability of Polymeric Matrix Composites presents a comprehensive knowledge-set of matrix, fiber and interphase behavior under long-term aging conditions, theoretical modeling and experimental methods. This book covers long-term constituent behavior, predictive methodologies, experimental validation and design practice. Readers will also find a discussion of various applications, including aging air craft structures, aging civil infrastructure, in addition to engines and high temperature applications.
Author: Abdul-Hamid Zureick
Publisher: Transportation Research Board
ISBN: 0309154855
Category : Technology & Engineering
Languages : en
Pages : 118
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Book Description
TRB's National Cooperative Highway Research Program (NCHRP) Report 655: Recommended Guide Specification for the Design of Externally Bonded FRP Systems for Repair and Strengthening of Concrete Bridge Elements examines a recommended guide specification for the design of externally bonded Fiber-Reinforced Polymer (FRP) systems for the repair and strengthening of concrete bridge elements. The report addresses the design requirements for members subjected to different loading conditions including flexure, shear and torsion, and combined axial force and flexure. The recommended guide specification is supplemented by design examples to illustrate its use for different FRP strengthening applications.
Author: Alessio Pipinato
Publisher: Elsevier
ISBN: 0323860141
Category : Technology & Engineering
Languages : en
Pages : 1048
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Book Description
Innovative Bridge Design Handbook: Construction, Rehabilitation, and Maintenance, Second Edition, brings together the essentials of bridge engineering across design, assessment, research and construction. Written by an international group of experts, each chapter is divided into two parts: the first covers design issues, while the second presents current research into the innovative design approaches used across the world. This new edition includes new topics such as foot bridges, new materials in bridge engineering and soil-foundation structure interaction. All chapters have been updated to include the latest concepts in design, construction, and maintenance to reduce project cost, increase structural safety, and maximize durability. Code and standard references have been updated. Completely revised and updated with the latest in bridge engineering and design Provides detailed design procedures for specific bridges with solved examples Presents structural analysis including numerical methods (FEM), dynamics, risk and reliability, and innovative structural typologies
Author: Hwai-Chung Wu
Publisher: Woodhead Publishing
ISBN: 0081006411
Category : Technology & Engineering
Languages : en
Pages : 340
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Book Description
Strengthening of Concrete Structures Using Fiber Reinforced Polymers (FRP): Design, Construction and Practical Applications presents a best practice guide on the structural design and strengthening of bridge structures using advanced Fiber Reinforced Polymer (FRP) composites. The book briefly covers the basic concepts of FRP materials and composite mechanics, while focusing on practical design and construction issues, including inspection and quality control, paying special attention to the differences in various design codes (US, Japan, and Europe) and recommendations. At present, several design guides from the US, Japan, and Europe are available. These guidelines are often inconsistent and do not cover all necessary design and inspection issues to the same degree of detail. This book provides a critical review and comparison of these guidelines, and then puts forward best practice recommendations, filling a significant gap in the literature, and serving as an important resource for engineers, architects, academics, and students interested in FRP materials and their structural applications. Written from a practitioner's point-of-view, it is a valuable design book for structural engineers all over the world. Includes a large quantity of design examples and structural software to facilitate learning and help readers perform routine design Provides recommendations for best practices in design and construction for the strengthening of bridge structures using advanced fiber-reinforced polymer (FRP) composites Presents comprehensive guidelines on design, inspection, and quality control, including laboratory and field testing information
Author: Edward G. Nawy
Publisher: CRC Press
ISBN: 1420007653
Category : Technology & Engineering
Languages : en
Pages : 1584
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Book Description
The first edition of this comprehensive work quickly filled the need for an in-depth handbook on concrete construction engineering and technology. Living up to the standard set by its bestselling predecessor, this second edition of the Concrete Construction Engineering Handbook covers the entire range of issues pertaining to the construction
Author: L C Hollaway
Publisher: Elsevier
ISBN: 1845694899
Category : Technology & Engineering
Languages : en
Pages : 416
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Book Description
The repair of deteriorated, damaged and substandard civil infrastructures has become one of the most important issues for the civil engineer worldwide. This important book discusses the use of externally-bonded fibre-reinforced polymer (FRP) composites to strengthen, rehabilitate and retrofit civil engineering structures, covering such aspects as material behaviour, structural design and quality assurance. The first three chapters of the book review structurally-deficient civil engineering infrastructure, including concrete, metallic, masonry and timber structures. FRP composites used in rehabilitation and surface preparation of the component materials are also reviewed. The next four chapters deal with the design of FRP systems for the flexural and shear strengthening of reinforced concrete (RC) beams and the strengthening of RC columns. The following two chapters examine the strengthening of metallic and masonry structures with FRP composites. The last four chapters of the book are devoted to practical considerations in the flexural strengthening of beams with unstressed and prestressed FRP plates, durability of externally bonded FRP composite systems, quality assurance and control, maintenance, repair, and case studies. With its distinguished editors and international team of contributors, Strengthening and rehabilitation of civil infrastructures using fibre-reinforced polymer (FRP) composites is a valuable reference guide for engineers, scientists and technical personnel in civil and structural engineering working on the rehabilitation and strengthening of the civil infrastructure. Reviews the use of fibre-reinforced polymer (FRP) composites in structurally damaged and sub-standard civil engineering structures Examines the role and benefits of fibre-reinforced polymer (FRP) composites in different types of structures such as masonry and metallic strengthening Covers practical considerations including material behaviour, structural design and quality assurance
Author: Hota V.S. GangaRao
Publisher: CRC Press
ISBN: 1420020196
Category : Technology & Engineering
Languages : en
Pages : 400
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Book Description
Although the use of composites has increased in many industrial, commercial, medical, and defense applications, there is a lack of technical literature that examines composites in conjunction with concrete construction. Fulfilling the need for a comprehensive, explicit guide, Reinforced Concrete Design with FRP Composites presents specific informat
Author: Amir Mirmiran
Publisher: Transportation Research Board National Research
ISBN:
Category : Bridges, Concrete
Languages : en
Pages : 86
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Book Description
This report presents recommended construction specifications to facilitate highway agencies' use of bonded fiber-reinforced polymer (FRP) composites for the repair and retrofit of concrete structures. These specifications cover the construction of FRP systems used as externally bonded or near surface-mounted reinforcement to enhance axial, shear, or flexural strength of a concrete member. These specifications are supplemented by a construction process control manual that provides a program for assuring a consistent and uniform control of quality and regulatory requirements.
Author: Dennis R. Mertz
Publisher: Transportation Research Board
ISBN: 0309087694
Category : Political Science
Languages : en
Pages : 88
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Book Description
Rising awareness of and increased attention to sexual harassment has resulted in momentum to implement sexual harassment prevention efforts in higher education institutions. Work on preventing sexual harassment is an area that has recently garnered a lot of attention, especially around education and programs that go beyond the standard anti-sexual harassment trainings often used to comply with legal requirements. On April 20-21, 2021, the National Academies of Sciences, Engineering, and Medicine hosted the workshop Developing Evaluation Metrics for Sexual Harassment Prevention Efforts. The workshop explored approaches and strategies for evaluating and measuring the effectiveness of sexual harassment interventions being implemented at higher education institutions and research and training sites, in order to assist institutions in transforming promising ideas into evidence-based best practices. Workshop participants also addressed methods, metrics, and measures that could be used to evaluate sexual harassment prevention efforts that lead to change in the organizational climate and culture and/or a change in behavior among community members. This publication summarizes the presentations and discussion of the workshop.
