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Author: Farshid Sefat
Publisher: Woodhead Publishing
ISBN: 0323859437
Category : Medical
Languages : en
Pages : 510
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Book Description
Principles of Biomaterials Encapsulation: Volume One, provides an expansive and in-depth resource covering the key principles, biomaterials, strategies and techniques for encapsulation. Volume One begins with an introduction to encapsulation, with subsequent chapters dedicated to a broad range of encapsulation principles and techniques, including spray chilling and cooling, microemulsion, polymerization, extrusion, cell microencapsulation and much more. This book methodically details each technique, assessing the advantages and disadvantages of each, allowing the reader to make an informed decision when using encapsulation in their research. Principles of Biomaterials Encapsulation: Volume One enables readers to learn about the various strategies and techniques available for encapsulation of a wide selection of biomedical substrates, such as drugs, cells, hormones, growth factors and so on. Written and edited by well-versed materials scientists with extensive clinical, biomedical and regenerative medicine experience, this book offers a deeply interdisciplinary look at encapsulation in translational medicine. As such, this book will provide a useful resource to a broad readership, including those working in the fields of materials science, biomedical engineering, regenerative and translational medicine, pharmacology, chemical engineering and nutritional science. Details the various biomaterials available for encapsulation, as well as advantages and disadvantages of conventional and contemporary biomaterials for encapsulations Describes a broad range of applications in regenerative medicine, uniquely bringing encapsulation into the worlds of translational medicine and tissue engineering Written and edited by well-versed materials scientists with extensive clinical, biomedical and regenerative medicine experience, offering an interdisciplinary approach
Author: Farshid Sefat
Publisher: Woodhead Publishing
ISBN: 0323859437
Category : Medical
Languages : en
Pages : 510
Get Book
Book Description
Principles of Biomaterials Encapsulation: Volume One, provides an expansive and in-depth resource covering the key principles, biomaterials, strategies and techniques for encapsulation. Volume One begins with an introduction to encapsulation, with subsequent chapters dedicated to a broad range of encapsulation principles and techniques, including spray chilling and cooling, microemulsion, polymerization, extrusion, cell microencapsulation and much more. This book methodically details each technique, assessing the advantages and disadvantages of each, allowing the reader to make an informed decision when using encapsulation in their research. Principles of Biomaterials Encapsulation: Volume One enables readers to learn about the various strategies and techniques available for encapsulation of a wide selection of biomedical substrates, such as drugs, cells, hormones, growth factors and so on. Written and edited by well-versed materials scientists with extensive clinical, biomedical and regenerative medicine experience, this book offers a deeply interdisciplinary look at encapsulation in translational medicine. As such, this book will provide a useful resource to a broad readership, including those working in the fields of materials science, biomedical engineering, regenerative and translational medicine, pharmacology, chemical engineering and nutritional science. Details the various biomaterials available for encapsulation, as well as advantages and disadvantages of conventional and contemporary biomaterials for encapsulations Describes a broad range of applications in regenerative medicine, uniquely bringing encapsulation into the worlds of translational medicine and tissue engineering Written and edited by well-versed materials scientists with extensive clinical, biomedical and regenerative medicine experience, offering an interdisciplinary approach
Author: Farshid Sefat
Publisher: Elsevier
ISBN: 0323853307
Category : Medical
Languages : en
Pages : 806
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Book Description
Principles of Biomaterials Encapsulation: Volume Two provides an expansive and in-depth resource covering the key principles, biomaterials, techniques and applications of encapsulation in translational medicine. The book details the various biomaterials available for encapsulation, including polymers, natural and synthetic biomaterials, porous materials, and more. The advantages and disadvantages of conventional and contemporary biomaterials for encapsulations are reviewed, along with advice on the most effective materials for both shell and core. The final part of the book describes a broad range of applications in regenerative medicine, uniquely bringing encapsulation into the worlds of translational medicine and tissue engineering. This book enables readers to learn about the pros and cons of different biomaterials for encapsulation, as well as how they can be utilized in many bodily systems and tissues, such as the respiratory, digestive, endocrine and cardiovascular systems. Written and edited by well-versed materials scientists with extensive clinical, biomedical and regenerative medicine experience, this book offers a deeply interdisciplinary look at encapsulation in translational medicine. Details the various biomaterials available for encapsulation, as well as the advantages and disadvantages of conventional and contemporary biomaterials for encapsulations Describes a broad range of applications in regenerative medicine, uniquely bringing encapsulation into the worlds of translational medicine and tissue engineering Written and edited by well-versed materials scientists with extensive clinical, biomedical and regenerative medicine experience, offering an interdisciplinary approach
Author: Lia Stanciu
Publisher: Academic Press
ISBN: 0128095245
Category : Medical
Languages : en
Pages : 369
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Book Description
Introductory Biomaterials enables undergraduate students in Biomedical, Chemical, Materials and other relevant Engineering disciplines to become familiar with the key concepts of Biomaterials principles: biocompatibility, structure-property-applications relationships, mechanical response of natural tissues, and cellular pathways for tissue-material ingrowth. Written in a clear, concise manner that weds theory with applications, this book helps students to understand the often intricate relationships between materials the implant devices that are made from them, and how the human body reacts to them. The book includes such concepts as requirements for metals, alloys, and ceramic materials to be used in load bearing implants (corrosion concepts, stress shielding, mechanical properties, composition), what properties of polymers impact their use in medicine (leaching and swelling, creep and stress relaxation); the tissue response to biomaterials, concepts related to drug delivery applications (polymer degradation, encapsulation), and tissue engineering (scaffold porosity, diffusion of nutrients, mechanical properties). Begins with structure-properties, followed immediately by their impact on actual biomaterials classes and devices, thus directly relating theory to applications (e.g. polymers to polymeric stents; metals to fracture fixation devices) Explains concepts in a clear, progressive manner, with numerous examples and figures to enhance student learning Covers all key biomaterials classes: metallic, ceramic, polymeric, composite and biological Includes a timely chapter on medical device regulation
Author: Joon B. Park
Publisher: CRC Press
ISBN: 9780849314919
Category : Technology & Engineering
Languages : en
Pages : 250
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Book Description
Biomaterials: Principles and Applications offers a comprehensive review of all the major biomaterials in this rapidly growing field. In recent years, the role of biomaterials has been influenced considerably by advances in many areas of biotechnology and science, as well as advances in surgical techniques and instruments. Comprising chapters contributed by a panel of international experts, this text provides a familiarity with the uses of materials in medicine and dentistry and the rational basis for these applications. It covers such subjects as biodegradable polymeric materials and their relation to tissue engineering, biologic materials, and biomaterials applications in soft and hard tissues. Nearly one hundred figures and tables further add to the value of this book. Concise, topical, and not overly technical — no other book covers the entire field of biomaterials so succinctly in one volume.
Author: Joyce Y. Wong
Publisher: CRC Press
ISBN: 1439872511
Category : Medical
Languages : en
Pages : 285
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Book Description
Most current applications of biomaterials involve structural functions, even in those organs and systems that are not primarily structural in their nature, or very simple chemical or electrical functions. Complex chemical functions, such as those of the liver, and complex electrical or electrochemical functions, such as those of the brain and sense organs, cannot be carried out by biomaterials at this time. With these basic concepts in mind, Biomaterials: Principles and Practices focuses on biomaterials consisting of different materials such as metallic, ceramic, polymeric, and composite. It highlights the impact of recent advances in the area of nano- and microtechnology on biomaterial design. Discusses the biocompatibility of metallic implants and corrosion in an in vivo environment Provides a general overview of the relatively bioinert, bioactive or surface-reactive ceramics, and biodegradable or resorbable bioceramics Reviews the basic chemical and physical properties of synthetic polymers, the sterilization of the polymeric biomaterials, the importance of the surface treatment for improving biocompatibility, and the application of the chemogradient surface for the study on cell-to-polymer interactions Covers the fundamentals of composite materials and their applications in biomaterials Highlights commercially significant and successful biomedical biodegradable polymers Examines failure modes of different types of implants based on material, location, and function in the body The book discusses the role of biomaterials as governed by the interaction between the material and the body, specifically, the effect of the body environment on the material and the effect of the material on the body.
Author: Stephen F. Badylak
Publisher: Woodhead Publishing
ISBN: 0128214562
Category : Medical
Languages : en
Pages : 296
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Book Description
Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an “inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative medicine. This book details methods, materials and strategies designed to regulate the host immune response following surgical implantation and thus facilitate specific local cell infiltration and tissue deposition. There has been a dramatic transformation in our understanding of the role of the immune system, both innate and adaptive; these changes include recognition of the plasticity of immune cells, especially macrophages, cross-talk between the immune system and stem cells, and the necessity for in situ transition between inflammatory and regulatory immune cell phenotypes. The exploitation of these findings and the design and manufacture of new biomaterials is occurring at an astounding pace. There is currently no book directed at the interdisciplinary principles guiding the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response. The challenge for academia, industry, and regulatory agencies to encourage innovation while assuring safety and maximizing efficacy has never been greater. Given the highly interdisciplinary requirements for the design, manufacture and use of immunomodulatory biomaterials, this book will prove a useful single resource across disciplines. Holistically covers the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response Provides a single reference for understanding and utilizing the host response in biomaterials design An international collaboration of leading researchers in the field offering a novel insight into this fast-growing area
Author: Emmanuel C. Opara
Publisher: Humana
ISBN: 9781493981779
Category : Science
Languages : en
Pages : 366
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Book Description
This volume provides a unique forum to review cell microencapsulation in a broad sense by exploring various cell types that have been encapsulated for different purposes, different approaches and devices used for microencapsulation, the biomaterials used in cell microencapsulation, the challenges to the technology, and the current status of its application in different clinical situations. This book is divided in five sections: Section I is an introductory part that discusses historical developments of the technology and its current challenges, as well as the various applications of cell microencapsulation; Section II discusses the main approaches and devices currently used in cell microencapsulation; Section III presents an overview of the various polymeric materials currently in use for cell microencapsulation and the enabling technologies to either monitor or enhance encapsulated cell function; Section IV gives specific examples of the methods used to encapsulate various cell types; and Section V provides an overview of the different clinical situations in which cell microencapsulation has been applied. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and practical, Cell Microencapsulation: Methods and Protocols is a valuable reference for researchers, engineers, clinicians, and other healthcare professionals, as well as food technologists who will find detailed descriptions of methods for the microencapsulation of specific cell types and their current of potential clinical and industrial applications. This volume also includes detailed information about the design and manufacture of different devices including large-scale production devices for use in cell microencapsulation.
Author: Stephen F Badylak
Publisher: Academic Press
ISBN: 0128005009
Category : Technology & Engineering
Languages : en
Pages : 460
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Book Description
Host Response to Biomaterials: The Impact of Host Response on Biomaterial Selection explains the various categories of biomaterials and their significance for clinical applications, focusing on the host response to each biomaterial. It is one of the first books to connect immunology and biomaterials with regard to host response. The text also explores the role of the immune system in host response, and covers the regulatory environment for biomaterials, along with the benefits of synthetic versus natural biomaterials, and the transition from simple to complex biomaterial solutions. Fields covered include, but are not limited to, orthopaedic surgery, dentistry, general surgery, neurosurgery, urology, and regenerative medicine. Explains the various categories of biomaterials and their significance for clinical applications Contains a range of extensive coverage, including, but not limited to, orthopedic, surgery, dental, general surgery, neurosurgery, lower urinary tract, and regenerative medicine Includes regulations regarding combination devices
Author: Sundararajan V. Madihally
Publisher: Artech House
ISBN: 1608070565
Category : Medical
Languages : en
Pages : 499
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Book Description
Describing the role of engineering in medicine today, this comprehensive volume covers a wide range of the most important topics in this burgeoning field. Supported with over 145 illustrations, the book discusses bioelectrical systems, mechanical analysis of biological tissues and organs, biomaterial selection, compartmental modeling, and biomedical instrumentation. Moreover, you find a thorough treatment of the concept of using living cells in various therapeutics and diagnostics. Structured as a complete text for students with some engineering background, the book also makes a valuable reference for professionals new to the bioengineering field. This authoritative textbook features numerous exercises and problems in each chapter to help ensure a solid understanding of the material.
Author: Buddy D. Ratner
Publisher: Elsevier
ISBN: 008047036X
Category : Science
Languages : en
Pages : 864
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Book Description
The second edition of this bestselling title provides the most up-to-date comprehensive review of all aspects of biomaterials science by providing a balanced, insightful approach to learning biomaterials. This reference integrates a historical perspective of materials engineering principles with biological interactions of biomaterials. Also provided within are regulatory and ethical issues in addition to future directions of the field, and a state-of-the-art update of medical and biotechnological applications. All aspects of biomaterials science are thoroughly addressed, from tissue engineering to cochlear prostheses and drug delivery systems. Over 80 contributors from academia, government and industry detail the principles of cell biology, immunology, and pathology. Focus within pertains to the clinical uses of biomaterials as components in implants, devices, and artificial organs. This reference also touches upon their uses in biotechnology as well as the characterization of the physical, chemical, biochemical and surface properties of these materials. Provides comprehensive coverage of principles and applications of all classes of biomaterials Integrates concepts of biomaterials science and biological interactions with clinical science and societal issues including law, regulation, and ethics Discusses successes and failures of biomaterials applications in clinical medicine and the future directions of the field Cover the broad spectrum of biomaterial compositions including polymers, metals, ceramics, glasses, carbons, natural materials, and composites Endorsed by the Society for Biomaterials
