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Author: Antonio M. Gotto
Publisher: Elsevier Publishing Company
ISBN:
Category : Medical
Languages : en
Pages : 432
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Book Description
In this rapidly evolving field of research, an enormous amount of new knowledge of lipoprotein structure, function and metabolism has emerged. The 1985 Nobel Prize-winning pioneering work of Brown and Goldstein on the LDL receptor has had a profound impact on developments in the field. This work is one of the many subjects reviewed in detail in this book. The volume begins with chapters on structure, then proceeds to analysis of lipid and lipoprotein dynamics, metabolism, function, genetics, and molecular biology. Lipoprotein genetics in molecular biology, the role of lipoprotein receptors, and Lp(a) - a topic underrepresented in volumes on lipoproteins, are another three such topics in an impressive volume. This work will mainly be of interest to researchers interested in lipid and lipoprotein structure and metabolism, but will also be of great value to clinical medicine and biology in general.
Author: Antonio M. Gotto
Publisher: Elsevier Publishing Company
ISBN:
Category : Medical
Languages : en
Pages : 432
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Book Description
In this rapidly evolving field of research, an enormous amount of new knowledge of lipoprotein structure, function and metabolism has emerged. The 1985 Nobel Prize-winning pioneering work of Brown and Goldstein on the LDL receptor has had a profound impact on developments in the field. This work is one of the many subjects reviewed in detail in this book. The volume begins with chapters on structure, then proceeds to analysis of lipid and lipoprotein dynamics, metabolism, function, genetics, and molecular biology. Lipoprotein genetics in molecular biology, the role of lipoprotein receptors, and Lp(a) - a topic underrepresented in volumes on lipoproteins, are another three such topics in an impressive volume. This work will mainly be of interest to researchers interested in lipid and lipoprotein structure and metabolism, but will also be of great value to clinical medicine and biology in general.
Author: J. C. Fruchart
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110873664
Category : Science
Languages : en
Pages : 420
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Book Description
No detailed description available for "Human Plasma Lipoproteins".
Author:
Publisher:
ISBN: 9780444803030
Category : Electronic books
Languages : en
Pages : 0
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Book Description
Author: Arnold von Eckardstein
Publisher: Springer
ISBN: 9783319096643
Category : Medical
Languages : en
Pages : 0
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Book Description
In this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts of therapeutic exploitation. The book is of interest to researchers in academia and industry focusing on lipoprotein metabolism, cardiovascular diseases and immunology as well as clinical pharmacologists, cardiologists, diabetologists, nephrologists and other clinicians interested in metabolic or inflammatory diseases.
Author:
Publisher:
ISBN:
Category : Coronary heart disease
Languages : en
Pages : 2
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Book Description
Author: Philip Barter
Publisher: CRC Press
ISBN: 0203304810
Category : Medical
Languages : en
Pages : 483
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Book Description
This volume gives up-to-date information on plasma lipid transport, the various categories of plasma lipid disorders and the relationship between plasma lipids, lipoproteins, and atherosclerotic disease.
Author: Angelo M. Scanu
Publisher: Marcel Dekker
ISBN:
Category : Blood lipoproteins
Languages : en
Pages : 536
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Book Description
Author: Alicia J. Jenkins
Publisher: Springer Science & Business Media
ISBN: 1461475546
Category : Medical
Languages : en
Pages : 466
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Book Description
Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin resistance is a hallmark of pre-diabetes and type 2 diabetes mellitus, and is characterized by impaired insulin-signaling transduction. Authoritative and comprehensive, Lipoproteins in Diabetes Mellitus details the many changes wrought by insulin resistance and diabetes mellitus on lipid and lipoprotein metabolism. The book begins by summarizing the various techniques to measure lipoproteins and their subclasses. The mechanisms by which insulin resistance and diabetes mellitus increase risk for atherosclerosis, diabetic retinopathy, and diabetic nephropathy are then explored in detail. Finally, the effects of lifestyle modification and the results of clinical trials using established and investigational drugs are discussed. An invaluable contribution to the literature, Lipoproteins in Diabetes Mellitus is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It will have a long-lasting and significant effect on the medical management of people with diabetes.
Author: Hubert Peeters
Publisher: Springer Science & Business Media
ISBN: 1468427814
Category : Science
Languages : en
Pages : 299
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Book Description
The amount of recent information collected about the molecular composition, structure, and function of the plasma lipoproteins, in man as well as in experimental animals, is very large. In this volume an assessment of our knowledge as it stands today has been organized within a framework of four general topics, the first about analytical data, the second about structure, the third about metab olism, and the last about molecular variation and pathology. Thus the analytical, theoretical, experimental, and applied aspects of the topic have been treated in conjunction with each other. The analytical data in human and nonhuman primates were obtained after ultracentrifugal or electrophoretic separation of the protein class from the native serum. Comparisons of various methods were not forgotten. The main categories of lipoproteins, namely High Density (HDL), Low Density (LDL), and Very Low Density (VLDL), are treated separately, and lipid moiety and the polypeptide moiety are carefully described. In the theoretical field of reassembly of lipoprotein particles by relipidizing delipidated polypeptides, the structural aspects of lipoprotein and the stabilizing effect of phospholipids on the poly peptide structure were studied. The opposite direction of the pro cess, namely degradation of a lipoprotein by means of lipolytic enzymes, has also been investigated and described.
Author: Claude L. Malmendier
Publisher: Springer Science & Business Media
ISBN: 146841268X
Category : Science
Languages : en
Pages : 248
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Book Description
Atherosclerosis which accounts in Western Europe for more than 40 % of deaths, is a generalized disease that develops slowly and is symptomless until lesions have become sufficiently severe to cause myocardial or cerebral infarction. Research on specific and precocious markers of atherosclerosis and the development of non invasive techniques for their early detection represent major challenges in biomedical field. We hope that this volume of edited papers, a consequence of the third international colloquium on atherosclerosis, conducted at the University of Brussels, Belgium through the support of the "Fondation de Recherche sur l' AtherosclE,rose" will contribute to this goal. Among the topics discussed the major ones were the mechanism of action of lipolytic enzymes, the deficiency or dysregulation of cellular receptors, the genetic deficiencies of apolipoproteins, and the panoply of external factors as diet, physical exercise, drugs, which mOdify the lipoprotein metabolism. Special interest was also devoted to potent techniques as kinetic analysis of metabolic tracers and use of monoclonal antibodies. Their contribution to the detection and treatment of atherosclerosis will be obviously essential in the future.
