Pathology, Toxicogenetics, and Criminalistics of Drug Abuse

Pathology, Toxicogenetics, and Criminalistics of Drug Abuse PDF Author: Steven B. Karch, MD, FFFLM
Publisher: CRC Press
ISBN: 9781420054569
Category : Law
Languages : en
Pages : 208

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Book Description
Extracted from the Drug Abuse Handbook, 2nd edition, to give you just the information you need at an affordable price. Pathology, Toxicogenetics, and Criminalistics of Drug Abuse presents a detailed introduction to the cutting-edge advances in this emerging field. Beginning with a definition and explanation of the scheduling of controlled substances, the book covers all illicit drugs, as well as several legitimate pharmaceutical preparations that are used illicitly, including steroids. It describes in detail the most common pathologic syndromes seen in the hearts, lungs, and central nervous systems of drug abusers and explains how inherited genetic defects and variations can alter drug effects. Written by leading investigators in the field, this useful volume describes the techniques most commonly used by forensic analysts including chemical confirmatory tests such as microcrystal identification and gas chromatography/mass spectrometry. The book reviews the basics of toxicogenetics, including the molecular changes in cardiac structure ("channelopathies") that may cause sudden death.

Pathology, Toxicogenetics, and Criminalistics of Drug Abuse

Pathology, Toxicogenetics, and Criminalistics of Drug Abuse PDF Author: Steven B. Karch, MD, FFFLM
Publisher: CRC Press
ISBN: 9781420054569
Category : Law
Languages : en
Pages : 208

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Book Description
Extracted from the Drug Abuse Handbook, 2nd edition, to give you just the information you need at an affordable price. Pathology, Toxicogenetics, and Criminalistics of Drug Abuse presents a detailed introduction to the cutting-edge advances in this emerging field. Beginning with a definition and explanation of the scheduling of controlled substances, the book covers all illicit drugs, as well as several legitimate pharmaceutical preparations that are used illicitly, including steroids. It describes in detail the most common pathologic syndromes seen in the hearts, lungs, and central nervous systems of drug abusers and explains how inherited genetic defects and variations can alter drug effects. Written by leading investigators in the field, this useful volume describes the techniques most commonly used by forensic analysts including chemical confirmatory tests such as microcrystal identification and gas chromatography/mass spectrometry. The book reviews the basics of toxicogenetics, including the molecular changes in cardiac structure ("channelopathies") that may cause sudden death.

Karch's Pathology of Drug Abuse

Karch's Pathology of Drug Abuse PDF Author: Steven B. Karch MD
Publisher: CRC Press
ISBN: 1439861471
Category : Law
Languages : en
Pages : 906

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Book Description
Written in the same accessible manner as previous editions, the fifth edition of Karch‘s Pathology of Drug Abuse is an essential guide to the pathology, toxicology, and pharmacology of commonly abused drugs. The book focuses on the investigation of drug-related deaths, practical approaches to the detection of drug abuse, and discussions of medical

Karch's Drug Abuse Handbook

Karch's Drug Abuse Handbook PDF Author: Steven Karch
Publisher: CRC Press
ISBN: 1351643126
Category : Law
Languages : en
Pages : 838

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Book Description
Karch’s Drug Abuse Handbook, Third Edition remains the quintessential compendium addressing the pharmacological, medical, and legal aspects of drugs and informing the forensic community of the latest scientific advances and emergent practices. For this edition, Dr. Karch has brought on clinical and forensic toxicology expert Dr. Bruce Goldberger, editor-in-chief of the Journal of Analytical Toxicology and president of the American Board of Forensic Toxicology, to serve as co-editor. In addition, world-renowned scientists and medical professionals have contributed their work and expertise in tackling the latest developments in drug testing, drug-related medical emergencies, and the drug toxicology. Topics addressed include genetic testing in drug death investigation, pathology, toxicogenetics, alcohol, post-mortem toxicology, new psychoactive substances, the latest legal issues and challenges as well as drugs and drug testing in sports, and the ethical, legal, and practical issues involved. Vivid pictures and diagrams throughout illustrate the pathological effects of drugs and the chemical make-up and breakdown of abused drugs. With unparalleled detail, the latest research and the highest level of authoritative medical scientific information, The Drug Abuse Handbook, Third Edition remains the definitive resource for drug related issues.

Karch's Pathology of Drug Abuse, Fourth Edition

Karch's Pathology of Drug Abuse, Fourth Edition PDF Author: Steven B. Karch
Publisher: CRC Press
ISBN: 9780849378805
Category : Law
Languages : en
Pages : 0

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Book Description
Written for practitioners in the field, this critically acclaimed bestseller provides authoritative information focused on the investigation of drug-related deaths and practical approaches to the detection of drug abuse. Organized to provide forensic investigators and pathologists with ready access to the authoritative and comprehensive information they need, Karch’s Pathology of Drug Abuse, Fourth Edition includes— • 171 new color photos and microphotographs • 46 tables of comparative information • 2,000 new references to the literature Authored by a World-Renowned Forensic Pathologist Steven B. Karch is a fellow in several forensic and toxicological societies and has served many years as consultant to both the legal community and the pharmaceutical industry in the United States and the United Kingdom. His bestselling resources can be found on the bookshelves of forensic experts and pathologists across the world. They include the classic Drug Abuse Handbook, and A Brief History of Cocaine, both in their second editions, available from CRC Press.

Karch's Pathology of Drug Abuse

Karch's Pathology of Drug Abuse PDF Author: D Hank Ellison
Publisher: CRC Press
ISBN: 9780367777906
Category :
Languages : en
Pages : 912

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Book Description
Written in the same accessible manner as previous editions, this comprehensive book is an essential reference covering the pathology, toxicology, and pharmacology of commonly and some uncommonly abused drugs. It focuses on investigating drug-related deaths, offers practical approaches to detecting drug abuse, and describes medical complications

Drug Abuse Handbook

Drug Abuse Handbook PDF Author: Steven B. Karch, MD, FFFLM
Publisher: CRC Press
ISBN: 9780849326370
Category : Law
Languages : en
Pages : 1152

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Book Description
This is the handbook that professionals who deal with problems related to drugs and drug abuse have been waiting for. The impressive list of more than 80 contributors, each experts and leaders in their field, testifies to the importance of this outstanding new handbook. The volume contains detailed discussions of drug-related issues in criminalistics, pathology, and toxicology. Impairment testing and the pharmacokinetics of abused drugs are examined in detail, as is the field of workplace drug testing, the use of alternate testing matrices, drugs in sports, addiction medicine, and drug-related medical emergencies. The handbook focuses on the most urgent drug abuse-related problems of today An entire section is devoted to alcohol abuse, including a scientific appraisal of the most common drunk driving defenses, complete with sample calculations. Problems of postmortem toxicology are thoroughly detailed and an appendix lists key references for the most widely used analytic methods. An in-depth analysis of legal questions, including fetal rights and workplace testing Examination of the principles of addiction medicine and how doctors handle substance abuse problems A section addressing drug use by athletes, including a summary of current Olympic Committee Regulations regarding substance use and the latest information on detecting abuse of Human Growth Hormone and Erythropoietin Whether you are approaching the issue of drug abuse from a medical, psychological, toxicological, or legal perspective, the Drug Abuse Handbook is the most authoritative and complete resource available.

An Introduction to the Work of a Medical Examiner

An Introduction to the Work of a Medical Examiner PDF Author: John J. Miletich
Publisher: Bloomsbury Publishing USA
ISBN: 0275995097
Category : Medical
Languages : en
Pages : 196

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Book Description
Medical examiners play an increasingly important role in society as unexpected and violent deaths increase, not only due to crime, but also due to new toxins in the environment, emerging diseases crossing from animals to humans, bizarre suicides, sadistic sexual practices, and other non-natural causes. John Miletich and Tia Lindstrom take us into the world of these medical detectives. Biological clues from bite marks and skin abnormalities to blood chemical levels and brain oxygenation are just some factors exposed in their quest for truth and justice. We learn the basics of death determination from rigor and livor mortis to signs of death by design, drug use, disease, suicide, and more. We also come to understand the tools of this work, from the Stryker's Saw to the grocer's scale, and tests that reveal factors from DNA evidence to toxins from insect bites. Each case begins with a biological mystery and ends with a conclusion that can provide loved ones with relief, or shock. Miletich, who trained at the Alberta Office of the Chief Medical Examiner and with the Royal Canadian Mounted Police, teams with Lindstrom to introduce readers to the medical examiner's role, including autopsy techniques and analysis. Twists and turns emerge as what was initially thought to be a murder proves to be suicide; what was suspected to be a natural death proves to be murder or environmental poisoning; or what was thought to be an accidental death proves to be something more sinister. This work includes appendices with guides to Medical Examiner organizations, seminars, and conventions.

Karch's Pathology of Drug Abuse

Karch's Pathology of Drug Abuse PDF Author: Steven B. Karch MD
Publisher: CRC Press
ISBN: 0849378818
Category : Law
Languages : en
Pages : 738

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Book Description
Written for practitioners in the field, this critically acclaimed bestseller provides authoritative information focused on the investigation of drug-related deaths and practical approaches to the detection of drug abuse. Organized to provide forensic investigators and pathologists with ready access to the authoritative and comprehensive information

Drug Abuse Handbook, Second Edition

Drug Abuse Handbook, Second Edition PDF Author: Steven B. Karch, MD, FFFLM
Publisher: CRC Press
ISBN: 1420003461
Category : Law
Languages : en
Pages : 1288

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Book Description
Following the well-received first edition, the Drug Abuse Handbook, Second Edition is a thorough compendium of the knowledge of the pharmacological, medical, and legal aspects of drugs. The book examines criminalistics, pathology, pharmacokinetics, neurochemistry, treatment, as well as drugs and drug testing in the workplace and in sports, and the ethical, legal, and practical issues involved. Dr. Karch gathers contributions from 80 leading experts in their respective fields to update and revise this second edition with more than 40 percent new material. New topics include genetic testing in drug death investigation, the neurochemistry of nicotine and designer amphetamines, genetic doping in sports, and the implications of the Daubert ruling on the admissibility of scientific evidence in federal court. Packed with the latest information in an easily accessible format, the book includes tables of all Scheduled Drugs, methods of Drug Quantitative Analysis, and a glossary of forensic toxicology terms. Vivid pictures and diagrams illustrate the pathological effects of drugs and the chemical make-up and breakdown of abused drugs. It includes more than 6000 references to the best sources in medicine, pharmacology, and the law. This book addresses specific problems in drug testing, drug-related medical emergencies, and the physical, neurochemical, and sociological phenomenon of addiction. With unparalleled detail and the highest level of authoritative information, The Drug Abuse Handbook, Second Edition is the definitive resource for drug related issues.

Pathology for Toxicologists

Pathology for Toxicologists PDF Author: Elizabeth McInnes
Publisher: John Wiley & Sons
ISBN: 1118755413
Category : Science
Languages : en
Pages : 210

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Book Description
Non-pathologists, such as toxicologists and study personnel, can find it difficult to understand the data they receive from pathologists. Toxicological pathologists write long, detailed and highly technical reports. Study personnel are under daily pressure to decide whether lesions described in pathology reports are treatment-related and thus important to the pharmaceutical company or whether the lesions are background changes and thus of little significance. Written by experienced toxicological pathologists, Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel serves to bridge the gap in the understanding of pathology data, enabling non-pathologists to more easily comprehend pathology reports, better integrate pathology data into final study reports and ask pathologists relevant questions about the test compound. This succinct, fully referenced, full colour book is suitable for toxicologists at all stages of their training or career who want to know more about the pathology encountered in laboratory animals used in safety studies. Key features include important chapters on spontaneous and target organ lesions in rats, mice, non-human primates, mini pigs, rabbits and beagle dogs as well as information on general pathology, macroscopic target organ lesions, ancillary pathology techniques, haematology, biochemistry and adversity. Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel includes: Colour diagrams explaining how lesions are caused by either external compounds or spontaneously The anatomic variations and background lesions of laboratory animals Advice on sampling tissues, necropsy, ancillary pathology techniques and recording data A chapter on the haematology and biochemistry of laboratory animals Full colour photographs of common macroscopic lesions encountered in laboratory animals A comprehensive glossary