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Author: Raymond C. Valentine
Publisher: CRC Press
ISBN: 1439813000
Category : Medical
Languages : en
Pages : 278
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Book Description
The physical-chemical properties of the omega-3 fatty acid DHA (docosahexaenoic acid) enable it to facilitate rapid biochemical processes in the membrane. This effect has numerous benefits, including those involved in the growth of bacteria, rapid energy generation, human vision, brain impulse, and photosynthesis, to name a few. Yet DHA also carries risks that can lead to cellular death and disease. Omega-3 Fatty Acids and the DHA Principle explores the roles of omega-3 fatty acids in cellular membranes ranging from human neurons and swimming sperm to deep sea bacteria, and develops a principle by which to assess their benefits and risks. The DHA Principle states that the blending of lipids to form cellular membranes is evolutionarily-honed to maximize benefit while minimizing risk, and that a complex blending code involving conformational dynamics, energy stress, energy yield, and chemical stability underlies all cellular membranes. This book lays the groundwork to understanding this code. It examines the evolution of DHA and the membrane and explores the general properties of omega-3s and other membrane lipids. It then focuses on cellular biology before shifting to a practical discussion on applications. The authors discuss the DHA Principle as applied to petroleum degradation, winemaking, global warming, molecular farming, aging, neurodegenerative diseases, and the prevention of colon cancer. Reflecting the increased public interest that has emerged over the years, this volume uses an integrative approach to explain the complex roles of omega-3s in the membrane. Incorporating principles from chemistry, cellular biology, evolution, and ecology, this work gives researchers in a variety of fields the building blocks to stimulate further study.
Author: Raymond C. Valentine
Publisher: CRC Press
ISBN: 1439813000
Category : Medical
Languages : en
Pages : 278
Get Book
Book Description
The physical-chemical properties of the omega-3 fatty acid DHA (docosahexaenoic acid) enable it to facilitate rapid biochemical processes in the membrane. This effect has numerous benefits, including those involved in the growth of bacteria, rapid energy generation, human vision, brain impulse, and photosynthesis, to name a few. Yet DHA also carries risks that can lead to cellular death and disease. Omega-3 Fatty Acids and the DHA Principle explores the roles of omega-3 fatty acids in cellular membranes ranging from human neurons and swimming sperm to deep sea bacteria, and develops a principle by which to assess their benefits and risks. The DHA Principle states that the blending of lipids to form cellular membranes is evolutionarily-honed to maximize benefit while minimizing risk, and that a complex blending code involving conformational dynamics, energy stress, energy yield, and chemical stability underlies all cellular membranes. This book lays the groundwork to understanding this code. It examines the evolution of DHA and the membrane and explores the general properties of omega-3s and other membrane lipids. It then focuses on cellular biology before shifting to a practical discussion on applications. The authors discuss the DHA Principle as applied to petroleum degradation, winemaking, global warming, molecular farming, aging, neurodegenerative diseases, and the prevention of colon cancer. Reflecting the increased public interest that has emerged over the years, this volume uses an integrative approach to explain the complex roles of omega-3s in the membrane. Incorporating principles from chemistry, cellular biology, evolution, and ecology, this work gives researchers in a variety of fields the building blocks to stimulate further study.
Author: Paul Greenberg
Publisher: Penguin
ISBN: 0698183460
Category : Nature
Languages : en
Pages : 276
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Book Description
By the bestselling author of Four Fish and American Catch, an eye-opening investigation of the history, science, and business behind omega-3 fatty acids, the "miracle compound" whose story is intertwined with human health and the future of our planet Omega-3 fatty acids have long been celebrated by doctors and dieticians as key to a healthy heart and a sharper brain. In the last few decades, that promise has been encapsulated in one of America's most popular dietary supplements. Omega-3s are today a multi-billion dollar business, and sales are still growing apace--even as recent medical studies caution that the promise of omega-3s may not be what it first appeared. But a closer look at the omega-3 sensation reveals something much deeper and more troubling. The miracle pill is only the latest product of the reduction industry, a vast, global endeavor that over the last century has boiled down trillions of pounds of marine life into animal feed, fertilizer, margarine, and dietary supplements. The creatures that are the victims of that industry seem insignificant to the untrained eye, but turn out to be essential to the survival of whales, penguins, and fish of all kinds, including many that we love to eat. Behind these tiny molecules is a big story: of the push-and-pull of science and business; of the fate of our oceans in a human-dominated age; of the explosion of land food at the expense of healthier and more sustainable seafood; of the human quest for health and long life at all costs. James Beard Award-winning author Paul Greenberg probes the rich and surprising history of omega-3s--from the dawn of complex life, when these compounds were first formed; to human prehistory, when the discovery of seafood may have produced major cognitive leaps for our species; and on to the modern era, when omega-3s may point the way to a bold new direction for our food system. With wit and boundless curiosity, Greenberg brings us along on his travels--from Peru to Antarctica, from the Canary Islands to the Amalfi Coast--to reveal firsthand the practice and repercussions of our unbalanced way of eating. Rigorously reported and winningly told, The Omega Principle is a powerful argument for a more deliberate and forward-thinking relationship to the food we eat and the oceans that sustain us.
Author: Ronald Ross Watson
Publisher: Academic Press
ISBN: 0128152397
Category : Medical
Languages : en
Pages : 518
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Book Description
Research has clearly established a link between omega fatty acids and general health, particularly cardiovascular health. Omega Fatty Acids in Brain and Neurological Health, Second Edition, illustrates the importance of omega-3 fatty acids in longevity, cognitive impairment and structure and function of the brain's neurons and also the adverse effects of omega-6 fatty acids on neurological function. This book encompasses some of the most recent research on the links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep and neurodegenerative diseases. This completely updated second edition focuses on the counterbalancing dietary and tissue omega-6 fatty acids as well as it studies the effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases. Provides a comprehensive introduction to omega-3 and omega-6 fatty acids in neurological health and directions for future research Features novel focus on the adverse effects of omega-6 fatty acids on neurological function and the counterbalancing of dietary and tissue omega-6 Illustrates the importance of omega-3 fatty acids in longevity and cognitive impairment Features new chapters on early effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases Discusses links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements
Author: Raymond C. Valentine
Publisher: CRC Press
ISBN: 1439874875
Category : Medical
Languages : en
Pages : 287
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Book Description
Studies with bacteria and other systems suggest that the omega-3 fatty acid DHA confers great benefits to neurons in maximizing both speed of neural impulses and energy efficiency. Unfortunately, studies also show that DHA’s ease of oxidation damages membrane integrity. Exploring this duality, Neurons and the DHA Principle proposes a new model for the causes of neurodegeneration, in which DHA-enriched membranes of neurons become dysfunctional and energetically wasteful, triggering the premature death of neurons. The challenge of this book is to digest how DHA acts as an essential building block of neurons while also conspiring for their assassination during aging. As the book reviews the extraordinary properties of DHA in life forms from deep-sea bacteria to human neurons, it asks: Is there a trade-off between speed and efficiency of brain function enabled by DHA versus longevity or life span? Has modern medicine advanced significantly in the treatment of the body but not necessarily of the brain? What are the molecular explanations for the decline in brain health during the age of longevity? A full accounting of the roles of DHA in neurons requires balancing the enormous benefits of these molecules against the risks. Introducing the dual chemical personalities of DHA from an evolutionary perspective, Neurons and the DHA Principle explores DHA from the standpoint of benefit–risk analysis, opening new perspectives for understanding how DHA functions in neurons.
Author: Robert S. Lees
Publisher: CRC Press
ISBN: 1000147592
Category : Technology & Engineering
Languages : en
Pages : 262
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Book Description
A report from research in the MIT Sea Grant College Program. Discusses the relationship between particular fatty acids found only in fish oil, and human health. Presents and evaluates information on the health effects of dietary fats generally; evidence that fish oil consumption affects the incidenc
Author: Corraldo Galli
Publisher: Springer Science & Business Media
ISBN: 1475720432
Category : Science
Languages : en
Pages : 433
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Book Description
On June 24-26, 1985, a major International Conference on the Hea1th Effects of P01yunsaturated Fatty Acids in Seafoods was held in Washington, D. C. The conference had two objectives: (1) to review the research data on the health effects of polyunsaturated fatty acids in seafoods in terms of the impact of omega-3 fatty acids on eicosanoid formation, thrombosis and inflammation, and the role of docosahexaenoic acid in membrane function and metabolism, and (2) to develop a research agenda to determine the spectrum of the health effects of polyunsaturated fatty acids of seafood origin in the American diet. The 1985 conference established the fact that omega-3 fatty acids of marine origin - eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) - play important roles in prostaglandin metabolism, thrombosis and atherosc1erosis, immunology and inflammation, and membrane function. In response to the conference recommendations, the Congress of the United States provided special funding for the establishment of a "test materials 1aboratory" within the US Department of Commerce to produce under documented quality contr01 the types and quanti ties of omega-3 te~3t materials required by biomedica1 researchers. The forms of test materials to be produced include refined fish oil, polyunsaturated fatty acid enhanced triglycerides, concentrates of esters of fatty acids, purified omega-3 fatty acids, and omega-3 mono-, di- and tri~lyceride mixtures.
Author: Vincenzo Tufarelli
Publisher: MDPI
ISBN: 3039438530
Category : Science
Languages : en
Pages : 754
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Book Description
The aim of this Special Issue is to publish high quality papers concerning poultry nutrition and the interrelations between nutrition, metabolism, microbiota and the health of poultry. Therefore, I invite submissions of recent findings, as original research or reviews, on poultry nutrition, including, but not limited to, the following areas: the effect of feeding on poultry meat end egg quality; nutrient requirements of poultry; the use of functional feed additives to improve gut health and immune status; microbiota; nutraceuticals; soybean meal replacers as alternative sources of protein for poultry; the effects of feeding poultry on environmental impacts; the use of feed/food by-products in poultry diet; and feed technology.
Author: Paul Greenberg
Publisher: Penguin
ISBN: 0143111116
Category : Nature
Languages : en
Pages : 306
Get Book
Book Description
By the bestselling author of Four Fish and American Catch, an eye-opening investigation of the history, science, and business behind omega-3 fatty acids, the "miracle compound" whose story is intertwined with human health and the future of our planet Omega-3 fatty acids have long been celebrated by doctors and dieticians as key to a healthy heart and a sharper brain. In the last few decades, that promise has been encapsulated in one of America's most popular dietary supplements. Omega-3s are today a multi-billion dollar business, and sales are still growing apace--even as recent medical studies caution that the promise of omega-3s may not be what it first appeared. But a closer look at the omega-3 sensation reveals something much deeper and more troubling. The miracle pill is only the latest product of the reduction industry, a vast, global endeavor that over the last century has boiled down trillions of pounds of marine life into animal feed, fertilizer, margarine, and dietary supplements. The creatures that are the victims of that industry seem insignificant to the untrained eye, but turn out to be essential to the survival of whales, penguins, and fish of all kinds, including many that we love to eat. Behind these tiny molecules is a big story: of the push-and-pull of science and business; of the fate of our oceans in a human-dominated age; of the explosion of land food at the expense of healthier and more sustainable seafood; of the human quest for health and long life at all costs. James Beard Award-winning author Paul Greenberg probes the rich and surprising history of omega-3s--from the dawn of complex life, when these compounds were first formed; to human prehistory, when the discovery of seafood may have produced major cognitive leaps for our species; and on to the modern era, when omega-3s may point the way to a bold new direction for our food system. With wit and boundless curiosity, Greenberg brings us along on his travels--from Peru to Antarctica, from the Canary Islands to the Amalfi Coast--to reveal firsthand the practice and repercussions of our unbalanced way of eating. Rigorously reported and winningly told, The Omega Principle is a powerful argument for a more deliberate and forward-thinking relationship to the food we eat and the oceans that sustain us.
Author: Cesarettin Alasalvar
Publisher: Springer Science & Business Media
ISBN: 3662098369
Category : Technology & Engineering
Languages : en
Pages : 224
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Book Description
Seafoods covers selected but vital topics of fish processing with an emphasis on quality, technology and nutraceutical applications in an up-to-date survey. The aspects of seafood quality covered range from the impact of slaughter procedures, through protein functionality, texture, flavour, histamine toxicity to the practical evaluation of quality and measurement. Technological aspects concentrate on automation in processing, waste-water treatment and reuse of scraps. Marine nutraceuticals/functional foods are discussed in detail. This book is highly recommended for scientists and technologists in the seafood industries, plus fish processing professionals, quality managers, and nutritonists..
Author: Raymond C. Valentine
Publisher: CRC Press
ISBN: 146659487X
Category : Medical
Languages : en
Pages : 259
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Book Description
More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age as our mitochondria age. It suggests a revised version of Harman’s famous hypothesis featuring mitochondrial oxidative and energy stresses as the root causes of aging. Human cells are protected from the ravages of aging by a battery of defensive systems including some novel mechanisms against membrane oxidation introduced in this book. This concept is consistent with recent discoveries showing that mitochondria-targeted antioxidants prevent Huntington’s disease, Parkinson’s disease, and traumatic brain disease in animal models of neurodegeneration. This book explores a unified theory of aging based on bioenergetics. It covers a variety of topics including an introduction to the science of human aging, the Darwinian selection of membranes enabling longevity, a revised mitochondrial membrane hypothesis of aging, and various mechanisms that protect human mitochondrial membranes, thereby enabling longevity.
