New Therapies in Advanced Cutaneous Malignancies PDF Download
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Author: Piotr Rutkowski
Publisher: Springer Nature
ISBN: 3030640094
Category : Medical
Languages : en
Pages : 457
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Book Description
This book provides a detailed overview of the activity and efficacy of new treatments and promising perspectives in the field of cutaneous malignancies. The first part of the book covers the basic molecular and immunological mechanisms. It then goes on to cover specific strategies in melanoma and non-melanoma skin cancers that, starting from the basic mechanisms, translate this information into clinical routine or translational research. This unique handbook comprises very practical structured descriptions of more than 10 new agents used in treatment of melanomas and skin carcinomas together with biological background of their mechanisms of action. It provides structured and up-to-date information about all therapeutics in cutaneous malignancies, making it extremely useful in clinical practice, for clinicians that need timely and focused information. Prepared by a group of international authors from expert melanoma centres in Europe, the book provides knowledge distilled from the diverse perspectives of the contributing authors (pathologists, translational scientists and clinicians). This book is of interest to medical oncologists, oncological surgeons, dermatologists and immunologists as well as biologists and pharmacologists.
Author: Piotr Rutkowski
Publisher: Springer Nature
ISBN: 3030640094
Category : Medical
Languages : en
Pages : 457
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Book Description
This book provides a detailed overview of the activity and efficacy of new treatments and promising perspectives in the field of cutaneous malignancies. The first part of the book covers the basic molecular and immunological mechanisms. It then goes on to cover specific strategies in melanoma and non-melanoma skin cancers that, starting from the basic mechanisms, translate this information into clinical routine or translational research. This unique handbook comprises very practical structured descriptions of more than 10 new agents used in treatment of melanomas and skin carcinomas together with biological background of their mechanisms of action. It provides structured and up-to-date information about all therapeutics in cutaneous malignancies, making it extremely useful in clinical practice, for clinicians that need timely and focused information. Prepared by a group of international authors from expert melanoma centres in Europe, the book provides knowledge distilled from the diverse perspectives of the contributing authors (pathologists, translational scientists and clinicians). This book is of interest to medical oncologists, oncological surgeons, dermatologists and immunologists as well as biologists and pharmacologists.
Author: Atsushi Otsuka
Publisher: Frontiers Media SA
ISBN: 2889457125
Category :
Languages : en
Pages : 137
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Book Description
New therapies are currently being developed in the field of skin cancer. In particular, advances in melanoma now represent the frontline of cancer immunotherapy, as immunological findings in the disease have led to the development of highly effective immune-checkpoint inhibitors. However, these immune-checkpoint inhibitors are only effective in a subset of patients, and may not work in other skin cancer types, thus highlighting the need for further innovation in the field of skin cancer treatment. The purpose of this Research Topic is therefore to provide an up-to-date overview of immune processes and new therapies for melanoma and other skin cancers in order to further stimulate the development of new and even more successful treatments.
Author: Debjani Sahni
Publisher: CRC Press
ISBN: 0429648987
Category : Medical
Languages : en
Pages : 290
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Book Description
Advanced skin cancer is one that has already metastasized beyond its primary origin, or one that has invaded underlying tissues such that surgical resection either is technically impossible or would lead to an unacceptable functional or cosmetic outcome. These skin cancers present a complex problem that requires the input of multiple specialties to delineate the best management plan. National guidelines utilize the best available data to guide management decisions. However, there is considerable leeway within the guidelines, enabling the ultimate care decision to be molded to best fit each individual patient. This book aims to provide instructional examples of patient cases where the input of the multidisciplinary team is critical in providing the most suitable care plan for the patient. CONTENTS: Melanoma * Squamous Cell Carcinoma * Basal Cell Carcinoma * Cutaneous Lymphoma * Kaposi’s Sarcoma * Dermatofibrosarcoma Protuberans * Merkel Cell Carcinoma * Rare Cancer Presentations
Author: Cecelia E Schmalbach
Publisher: Elsevier Health Sciences
ISBN: 0323813186
Category : Medical
Languages : en
Pages : 229
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Book Description
This issue of Otolaryngologic Clinics, guest edited by Drs. Cecelia E. Schmalbach and Kelly M. Malloy, is dedicated to Head and Neck Cutaneous Cancer. This issue is one of six selected each year by the series Consulting Editor, Dr. Sujana S. Chandrasekhar. Cutaneous cancer rates are growing at epidemic proportions and consequently lead to a significant health care burden. This issue opens with an overview of the related biology, epidemiology, and preventative measures. A contemporary review of cutaneous cancer management will be provided to include the roles of sentinel node biopsy, surgery, radiation therapy, and systemic therapy. Cutaneous cancers impact the geriatric patient population, so ethical considerations and non-surgical management are emphasized.
Author: Reinhard Dummer
Publisher: Springer Science & Business Media
ISBN: 3642050727
Category : Medical
Languages : en
Pages : 398
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Book Description
Over the last decades the incidence of skin cancers is dramatically increasing world-wide. This is not only confined to the incidence of melanoma but includes also other skin cancers such as basal cell carcinomas. Based on the recent WHO classification of skin cancers, this lavishly illustrated reference book covers comprehensively the epidemiology, histology and pathology, as well as diagnostic signs and treatment options of skin cancers. Homogenously and reader-friendly structured, it links the diagnostic and genetic features of each disease in order to guide the reader to the most appropriate therapeutic strategies for the best possible treatment outcome. In order to demonstrate the world wide activities in the field, all chapters cover the variations of the individual experiences and expertise in different nations.
Author: Lindsay C. Strowd
Publisher: Elsevier Health Sciences
ISBN: 0323708951
Category : Medical
Languages : en
Pages :
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Book Description
This issue of Dermatologic Clinics, guest edited by Dr. Lindsay C. Strowd of Wake Forest Baptist Health, is devoted to the Intersection of Dermatology and Oncology. This issue focuses on Melanoma, Nonmelanoma Skin Cancer, Cutaneous Lymphoma, Other Cutaneous Malignancies, Special Topics in Skin Cancer Diagnosis and Treatment, Dermatology in the Diagnosis of Non-cutaneous Malignancy, Dermatology in the Management of Non-cutaneous Malignancy, and Genodermatoses with Neoplastic Behavior. Articles in this issue include: Update on current treatment recommendations for primary cutaneous melanoma; Nonsurgical treatments for advanced melanoma; Update on current treatment recommendations for NMSC; Nonsurgical treatments for NMSC; Diagnosis and management of CBCL; Diagnosis and management of CTCL; Lymphomatoid papulosis and other lymphoma-like diseases (PLC, PLEVA, CD30+ disease); Dermatofibrosarcoma protuberans updates; Merkel cell carcinoma updates; Kaposi sarcoma updates; Skin cancer in skin of color patients; Skin cancer detection technology; Paraneoplastic diseases; Cutaneous metastases of internal tumors; Cutaneous side effects of chemotherapy agents; GVHD treatment updates; Phakomatoses (NF, TS); and Hereditary tumor syndromes with skin involvement (Gorlins, Lynch, XP, etc.).
Author: Miroslav Blumenberg
Publisher: BoD – Books on Demand
ISBN: 1789230942
Category : Medical
Languages : en
Pages : 214
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Book Description
Human skin cancers, the most common type of tumors, represent a significant health burden. The deadliest is unquestionably melanoma. Half of melanomas have an activating mutation in the BRAF gene, prompting development of novel drugs, vemurafenib and dabrafenib, specifically targeting mutated BRAF. Trametinib and cobimetinib, which block MEK, a BRAF effector protein, have been used in combination with BRAF inhibitors. A promising new melanoma treatment is immunotherapy, approach that boosts patient's own immune system to attack cancer. Pembrolizumab and nivolumab inhibit PD-1, whereas Ipilimumab targets CTLA-4, another immunity check point, to boost the immune response. Here we focus on pathways, mechanisms, targets and treatments of human skin cancers, with particular emphasis on the new developments in the research on melanomas.
Author: Darrell S. Rigel
Publisher: Elsevier Health Sciences
ISBN: 1437736149
Category : Medical
Languages : en
Pages : 713
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Book Description
Cancer of the Skin, edited by Drs. Rigel, Robinson, Ross, Friedman, Cockerell, Lim, Stockfleth, and Kirkwood, is your complete, multimedia guide to early diagnosis and effective medical and surgical treatment of melanoma and other skin cancers. Thoroughly updated with 11 new chapters, this broad-based, comprehensive reference provides you with the latest information on clinical genetics and genomics of skin cancer, targeted therapy for melanoma, the Vitamin D debate concerning the risks and benefits of sun exposure, and other timely topics. A new, multi-disciplinary team of contributors and editors comprised of leading experts in this field offers truly diverse perspectives and worldwide best practices. Broaden your understanding of all aspects of skin cancer—from the underlying biology to clinical manifestations of the disease to diagnosis, and medical and surgical treatment—with this easy-to-use, comprehensive, multimedia reference. See conditions as they appear in practice with guidance from detailed full-color images and step-by-step procedural videos. Stay current with the latest advancements and therapies! 11 new chapters cover clinical genetics and genomics of skin cancer, targeted therapy for melanoma, the Vitamin D debate concerning the risks and benefits of sun exposure, and other essential topics. Get truly diverse perspectives and worldwide best practices from a new, multi-disciplinary team of contributors and editors comprised of the world’s leading experts Access the complete text online—including image bank and video library—at www.expertconsult.com
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
New therapies are currently being developed in the field of skin cancer. In particular, advances in melanoma now represent the frontline of cancer immunotherapy, as immunological findings in the disease have led to the development of highly effective immune-checkpoint inhibitors. However, these immune-checkpoint inhibitors are only effective in a subset of patients, and may not work in other skin cancer types, thus highlighting the need for further innovation in the field of skin cancer treatment. The purpose of this Research Topic is therefore to provide an up-to-date overview of immune processes and new therapies for melanoma and other skin cancers in order to further stimulate the development of new and even more successful treatments.
Author: Eggert Stockfleth
Publisher: Springer
ISBN: 9783540872160
Category : Medical
Languages : en
Pages : 226
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Book Description
Skin cancer is the most common malignant neoplasm and its incidence is rising worldwide. The epidemic increase in such tumors calls for efficient management by the application of appropriate guidelines for therapy and prevention. Clinicians managing these patients need to keep up to date with the latest advances, allowing them to provide optimal treatment. This practical guide offers the reader a comprehensive overview of the options for the diagnosis, treatment, and prevention of cutaneous cancer. It covers all common skin cancers and also rarer lesions. Employing an "evidence-based medicine" approach, this truly international work presents a well-illustrated text in a reader-friendly format with step-by-step guidelines and visual flowcharts. Dermatologists, oncologists, and all other interested physicians will find this book an extraordinarily valuable resource for the clinical management of cutaneous cancer in their daily practice.
