Molecular Tools and Infectious Disease Epidemiology

Molecular Tools and Infectious Disease Epidemiology PDF Author: Betsy Foxman
Publisher: Academic Press
ISBN: 9780128102312
Category : Medical
Languages : en
Pages : 350

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Book Description
The application of modern molecular genetic and biologic techniques to infectious disease epidemiology dramatically improves measurement of disease and putative risk factors, increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. We examine these opportunities and methodologic challenges giving specific examples. The book will be written for the reader with limited understanding of genetics, biology and epidemiology. Presents the key points of consideration when integrating molecular biology and epidemiologyDiscusses how using molecular tools in epidemiologic research affects program design and conductConsiders the ethical concerns that arise in molecular epidemiologic studiesProvides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field

Molecular Tools and Infectious Disease Epidemiology

Molecular Tools and Infectious Disease Epidemiology PDF Author: Betsy Foxman
Publisher: Academic Press
ISBN: 9780128102312
Category : Medical
Languages : en
Pages : 350

Get Book

Book Description
The application of modern molecular genetic and biologic techniques to infectious disease epidemiology dramatically improves measurement of disease and putative risk factors, increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. We examine these opportunities and methodologic challenges giving specific examples. The book will be written for the reader with limited understanding of genetics, biology and epidemiology. Presents the key points of consideration when integrating molecular biology and epidemiologyDiscusses how using molecular tools in epidemiologic research affects program design and conductConsiders the ethical concerns that arise in molecular epidemiologic studiesProvides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field

Molecular Tools and Infectious Disease Epidemiology

Molecular Tools and Infectious Disease Epidemiology PDF Author: Betsy Foxman
Publisher: Academic Press
ISBN: 9780080920849
Category : Science
Languages : en
Pages : 240

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Book Description
Molecular Tools and Infectious Disease Epidemiology examines the opportunities and methodologic challenges in the application of modern molecular genetic and biologic techniques to infectious disease epidemiology. The application of these techniques dramatically improves the measurement of disease and putative risk factors, increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. This book presents the key points of consideration when integrating molecular biology and epidemiology; discusses how using molecular tools in epidemiologic research affects program design and conduct; considers the ethical concerns that arise in molecular epidemiologic studies; and provides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field. The book is recommended for graduate and advanced undergraduate students studying infectious disease epidemiology and molecular epidemiology; and for the epidemiologist wishing to integrate molecular techniques into his or her studies. Presents the key points of consideration when integrating molecular biology and epidemiology Discusses how using molecular tools in epidemiologic research affects program design and conduct Considers the ethical concerns that arise in molecular epidemiologic studies Provides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field

Molecular Epidemiology

Molecular Epidemiology PDF Author: Paul A. Schulte
Publisher: Academic Press
ISBN: 0323138578
Category : Science
Languages : en
Pages : 588

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Book Description
This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.

Molecular Epidemiology of Infectious Diseases

Molecular Epidemiology of Infectious Diseases PDF Author: Lee W. Riley
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 376

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Book Description
Designed as both a textbook and a reference, this book outlines the principles, methods, and application of this new discipline of public health. Techniques used in the field of molecular biology have been recognized as critical tools in solving infectious disease problems. This introductory volume, distinguishing molecular epidemiology from taxonomy and phylogeny, will familiarize epidemiologists with molecular biology and molecular biologists with epidemiology, and presents vocabulary and concepts of both fields to infectious disease clinicians.

Genetics and Evolution of Infectious Diseases

Genetics and Evolution of Infectious Diseases PDF Author: Michel Tibayrenc
Publisher: Elsevier
ISBN: 0123848903
Category : Medical
Languages : en
Pages : 773

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Book Description
Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field

New Frontiers of Molecular Epidemiology of Infectious Diseases

New Frontiers of Molecular Epidemiology of Infectious Diseases PDF Author: Serge Morand
Publisher: Springer Science & Business Media
ISBN: 9400721145
Category : Medical
Languages : en
Pages : 335

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Book Description
Molecular epidemiology has recently broaden its focuses due to the development of molecular tools but also by incorporating advances of other fields such as mathematical epidemiology, molecular ecology, population genetics and evolution. Facing new risks of emerging and re-emerging infectious diseases that are threats for humans and their livestock, the objectives of molecular epidemiology include: - the development of molecular tools, genotyping and gene expression - the incorporation of concepts and results of population genetics of infectious diseases - the integration of recent advances in theoretical epidemiology and evolutionary ecology of diseases - a better understanding of transmission for the development of risk factors analyses. This book will demonstrate how the latest developments in molecular tools and in epidemiology can be integrated with studies of host-pathogen interactions. Besides a strong theoretical component, there will also be an emphasis on applications in the fields of epidemiology, public health, veterinary medicine, and health ecology. Students and researchers in the fields of epidemiology, animal and human health, evolutionary ecology, parasitology are the main potential readers of the book, as well as a broader audience from veterinary medicine and conservation.

Infectious Disease Epidemiology

Infectious Disease Epidemiology PDF Author: Kenrad E. Nelson
Publisher: Jones & Bartlett Learning
ISBN: 0763728799
Category : Medical
Languages : en
Pages : 1226

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Book Description
Covers a range of essential topics from a survey of important historical epidemics to study designs for infectious disease investigations. The first part of the text covers ID epidemiology background and methodology, whereas the second focuses on specific diseases as examples of different transmission modalities. TB, HIV and Influenza are among the pathogens discussed in great detail. Includes four new chapters on immunology, measles, meningococcal disease, and vector-borne infections. The HIV chapter has been expanded to include issues of host genetics as well as a review of behavioral interventions.

Global Infectious Disease Surveillance and Detection

Global Infectious Disease Surveillance and Detection PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309111145
Category : Medical
Languages : en
Pages : 284

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Book Description
Early detection is essential to the control of emerging, reemerging, and novel infectious diseases, whether naturally occurring or intentionally introduced. Containing the spread of such diseases in a profoundly interconnected world requires active vigilance for signs of an outbreak, rapid recognition of its presence, and diagnosis of its microbial cause, in addition to strategies and resources for an appropriate and efficient response. Although these actions are often viewed in terms of human public health, they also challenge the plant and animal health communities. Surveillance, defined as "the continual scrutiny of all aspects of occurrence and spread of a disease that are pertinent to effective control", involves the "systematic collection, analysis, interpretation, and dissemination of health data." Disease detection and diagnosis is the act of discovering a novel, emerging, or reemerging disease or disease event and identifying its cause. Diagnosis is "the cornerstone of effective disease control and prevention efforts, including surveillance." Disease surveillance and detection relies heavily on the astute individual: the clinician, veterinarian, plant pathologist, farmer, livestock manager, or agricultural extension agent who notices something unusual, atypical, or suspicious and brings this discovery in a timely way to the attention of an appropriate representative of human public health, veterinary medicine, or agriculture. Most developed countries have the ability to detect and diagnose human, animal, and plant diseases. Global Infectious Disease Surveillance and Detection: Assessing the Challenges-Finding Solutions, Workshop Summary is part of a 10 book series and summarizes the recommendations and presentations of the workshop.

Encyclopedia of Infectious Diseases

Encyclopedia of Infectious Diseases PDF Author: Michel Tibayrenc
Publisher: John Wiley & Sons
ISBN: 0470114193
Category : Science
Languages : en
Pages : 807

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Book Description
Discover how the application of novel multidisciplinary, integrative approaches and technologies are dramatically changing our understanding of the pathogenesis of infectious diseases and their treatments. Each article presents the state of the science, with a strong emphasis on new and emerging medical applications. The Encyclopedia of Infectious Diseases is organized into five parts. The first part examines current threats such as AIDS, malaria, SARS, and influenza. The second part addresses the evolution of pathogens and the relationship between human genetic diversity and the spread of infectious diseases. The next two parts highlight the most promising uses of molecular identification, vector control, satellite detection, surveillance, modeling, and high-throughput technologies. The final part explores specialized topics of current concern, including bioterrorism, world market and infectious diseases, and antibiotics for public health. Each article is written by one or more leading experts in the field of infectious diseases. These experts place all the latest findings from various disciplines in context, helping readers understand what is currently known, what the next generation of breakthroughs is likely to be, and where more research is needed. Several features facilitate research and deepen readers' understanding of infectious diseases: Illustrations help readers understand the pathogenesis and diagnosis of infectious diseases Lists of Web resources serve as a gateway to important research centers, government agencies, and other sources of information from around the world Information boxes highlight basic principles and specialized terminology International contributions offer perspectives on how infectious diseases are viewed by different cultures A special chapter discusses the representation of infectious diseases in art With its multidisciplinary approach, this encyclopedia helps point researchers in new promising directions and helps health professionals better understand the nature and treatment of infectious diseases.

Public Health Systems and Emerging Infections

Public Health Systems and Emerging Infections PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 9780309183772
Category : Medical
Languages : en
Pages : 128

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Book Description
The Forum on Emerging Infections was created in 1996 in response to a request from the Centers for Disease Control and Prevention and the National Institutes of Health. The goal of the forum is to provide structured opportunities for representatives from academia, industry, professional and interest groups, and government to examine and discuss scientific and policy issues that relate to research, prevention, detection, and management of emerging infectious diseases. A critical part of this mission has been the convening of a series of workshops. Public Health Systems and Emerging Infections summarizes the fourth in a series of five workshops. With a focus on our knowledge and understanding of the role of private and public health sectors in emerging infectious disease surveillance and response, the participants explored the effects of privatization of public health laboratories and the modernization of public health care. The issues discussed included epidemiological investigation, surveillance, communication, coordination, resource allocations, and economic support.