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Author: Andres Trostchansky
Publisher: Springer
ISBN: 3030114880
Category : Medical
Languages : en
Pages : 198
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Book Description
The purpose of this book is to introduce the readers on the perspective of the role that unsaturated fatty acids and complex lipids play on health and disease. Bioactive lipids can be modified affecting membrane composition, structure and fluidity in addition to changes in cell signaling associated to lipid-protein (membrane receptors) interactions, issues that are addressed by the authors. This book analyzes key topics involving bioactive lipids and their role in normal signaling and the mechanisms of disease. The book navigates from structural studies of oxidized and non-oxidized lipids to the reactions and cell signaling processes that bioactive lipids play in cardiovascular and neurodegenerative diseases. The book contains the recent advances reported in the literature about lipidomics as well as the role that lipid-derived compounds exert on unfolded protein response and lipid metabolism and disease. This book represents a state of the art introduction to lipid metabolism from a biochemical to an in vivo overview being an useful tool for students and investigators. We hope the mechanistic observations on the role of bioactive lipids in health and disease serve a perspective to improve the existing treatments or propose new lipid-based pharmacology
Author: Andres Trostchansky
Publisher: Springer
ISBN: 3030114880
Category : Medical
Languages : en
Pages : 198
Get Book
Book Description
The purpose of this book is to introduce the readers on the perspective of the role that unsaturated fatty acids and complex lipids play on health and disease. Bioactive lipids can be modified affecting membrane composition, structure and fluidity in addition to changes in cell signaling associated to lipid-protein (membrane receptors) interactions, issues that are addressed by the authors. This book analyzes key topics involving bioactive lipids and their role in normal signaling and the mechanisms of disease. The book navigates from structural studies of oxidized and non-oxidized lipids to the reactions and cell signaling processes that bioactive lipids play in cardiovascular and neurodegenerative diseases. The book contains the recent advances reported in the literature about lipidomics as well as the role that lipid-derived compounds exert on unfolded protein response and lipid metabolism and disease. This book represents a state of the art introduction to lipid metabolism from a biochemical to an in vivo overview being an useful tool for students and investigators. We hope the mechanistic observations on the role of bioactive lipids in health and disease serve a perspective to improve the existing treatments or propose new lipid-based pharmacology
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309039940
Category : Medical
Languages : en
Pages : 765
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Book Description
Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
Author: National Academy of Sciences
Publisher: National Academies Press
ISBN: 0309040493
Category : Medical
Languages : en
Pages : 190
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Book Description
Results from the National Research Council's (NRC) landmark study Diet and health are readily accessible to nonscientists in this friendly, easy-to-read guide. Readers will find the heart of the book in the first chapter: the Food and Nutrition Board's nine-point dietary plan to reduce the risk of diet-related chronic illness. The nine points are presented as sensible guidelines that are easy to follow on a daily basis, without complicated measuring or calculatingâ€"and without sacrificing favorite foods. Eat for Life gives practical recommendations on foods to eat and in a "how-to" section provides tips on shopping (how to read food labels), cooking (how to turn a high-fat dish into a low-fat one), and eating out (how to read a menu with nutrition in mind). The volume explains what protein, fiber, cholesterol, and fats are and what foods contain them, and tells readers how to reduce their risk of chronic disease by modifying the types of food they eat. Each chronic disease is clearly defined, with information provided on its prevalence in the United States. Written for everyone concerned about how they can influence their health by what they eat, Eat for Life offers potentially lifesaving information in an understandable and persuasive way. Alternative Selection, Quality Paperback Book Club
Author: Corinne M. Spickett
Publisher: CRC Press
ISBN: 1482202867
Category : Medical
Languages : en
Pages : 440
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Book Description
Oxidative modification of lipids and phospholipids—including radical damage, halogenation, and nitration—result in significant changes to the chemical properties of the molecules, which in turn have a major effect on their biochemical functions. Lipid oxidation has long been regarded as a deleterious process responsible for lipid rancidity, loss of function, and generation of toxic products. However in recent years, research has also focused on the non-detrimental physiological and pathological effects of these chemical reactions. Lipid Oxidation in Health and Disease provides an up-to-date review of the role of oxidized lipid products in physiological and pathophysiological processes. Covering the diverse topics that contribute to research in this important field, this book explores: The mechanisms of lipid oxidation, both enzymatic and non-enzymatic Antioxidant defenses and lipid oxidation Lipid oxidation products and cell signaling The roles of oxidized lipids in specific diseases—including cardiovascular, neurodegenerative, and metabolic disorders, as well as in cancer Drug targeting and the therapeutic potential of oxidized lipids Accurate measurement of the formation of lipid oxidation products and investigation of their biological effects and roles in disease are critical to biomedical science and new targeted therapeutics. Written by acknowledged experts in the field, this book provides a broad survey of both established knowledge and recent findings on the action of oxidized lipid products on cell signaling and gene expression in health and disease.
Author: LERAY Claude
Publisher: Lavoisier
ISBN: 2743064919
Category :
Languages : fr
Pages : 334
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Book Description
Les substances lipidiques ont longtemps été négligées par les physiologistes, mais des recherches épidémiologiques les ont récemment portées sur le devant de la scène, notamment au travers de leur intérêt dans les domaines de la nutrition et surtout de la santé chez l’Homme. Outre leur importance énergétique, les lipides interviennent dans de nombreux mécanismes cellulaires dont les dérèglements peuvent conduire à des pathologies parfois graves. En effet, en plus de leur impact sur les maladies métaboliques, les systèmes cardiovasculaire et immunitaire et les processus de cancérisation, le système nerveux central peut lui aussi être altéré à des degrés divers par une carence ou un déséquilibre entre les constituants lipidiques ingérés. Après quelques rappels historiques sur la découverte des lipides et leur utilisation, une première partie décrit les principaux lipides présents dans notre ration alimentaire. Puis, les besoins avérés ou éventuels de l’Homme en divers acides gras, stérols et vitamines appartenant au groupe des lipides, sont passés en revue. Enfin, l’impact des principaux lipides sur des pathologies naguère encore peu explorées sous cet aspect est exposé en détail. Les lipides – Nutrition et santé présente, de façon synthétique, un très large panorama de toutes les facettes des lipides, des acides gras aux corps gras les moins abondants, mais tout aussi importants pour l’équilibre de notre organisme. Il permet aux spécialistes de revisiter les principales sources de lipides présentes dans notre alimentation en insistant sur leur production et leur composition. Cet ouvrage s’adresse aux chercheurs, médecins généralistes et spécialistes, diététiciens et étudiants évoluant dans de nombreux domaines tels que la biologie cellulaire, la nutrition ou encore la pharmacologie.
Author: Claudio Galli
Publisher: S. Karger AG (Switzerland)
ISBN: 9783805560405
Category : Acides gras - Effets physiologiques
Languages : en
Pages : 0
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Book Description
Author: Peter Quinn
Publisher: Springer Science & Business Media
ISBN: 1402088310
Category : Medical
Languages : en
Pages : 603
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Book Description
Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.
Author: Ronald Ross Watson
Publisher: Academic Press and AOCS Press
ISBN: 9781630670368
Category : Technology & Engineering
Languages : en
Pages : 0
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Book Description
Handbook of Lipids in Human Function: Fatty Acids presents current research relating to health issues whose impact may be modified by adopting personalized diets and lifestyle interventions of the consumption of fatty acids. Addressing cardiovascular and neurological diseases as well as cancer, obesity, inflammatory conditions, and lung disease, the authors correlate lipid sources with specific conditions, providing important insights into preventative as well as response-based actions designed to positively impact health outcomes. The material is presented in 29 chapters and brings together the research and work of an international team of experts. designed to bridge the gap between traditional approaches to dietary interventions and leading edge integrated health strategies, Handbook of Lipids in Human Function: Fatty Acids is a valuable resource for researchers and clinicians.
Author: Michael I. Gurr
Publisher: John Wiley & Sons
ISBN: 1118501101
Category : Science
Languages : en
Pages : 448
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Book Description
For the 6th Edition of this highly regarded textbook devoted to lipids, the title has been modified from Lipid Biochemistry to Lipids to acknowledge the coming together of biological and medical sciences, the increasingly blurred boundaries between them and the growing importance of lipids in diverse aspects of science and technology. The principal aims of this new edition - to inform students and researchers about lipids, to assist teachers and encourage further research – have not changed since previous editions. Significant advances in lipid science have demanded yet another extensive rewriting for this edition, with the addition of two new authors, to cover new knowledge of genes coding for proteins involved in lipid metabolism, the many lipids involved in cell signalling, the roles of lipids in health and disease and new developments in biotechnology in support of agriculture and industry. An introductory chapter summarizes the types of lipids covered and their identification and provides a guide to the contents. Chapters contain boxes illustrating special topics, key point summaries and suggested further reading. Lipids: Sixth Edition provides a huge wealth of information for upper-level students of biological and clinical sciences, food science and nutrition, and for professionals working in academic and industrial research. Libraries in all universities and research establishments where biological, medical and food and nutritional sciences are studied and taught should have copies of this excellent and comprehensive new edition on their shelves.
Author: Johnny Stiban
Publisher: Springer Nature
ISBN: 3030211622
Category : Science
Languages : en
Pages : 153
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Book Description
This book is about the various roles of bioactive ceramides and other sphingolipids in cellular biology. The enigmatic biophysical and biochemical properties of ceramides and their propensity to influence membranes whether as rafts or protein-permeable channels are heavily discussed. Metabolism of ceramides and their metabolites is also focused with ceramide synthase family of proteins being a target of extensive review. Ceramide 1-phosphate and other sphingolipids are also presented in cellular physiology and pathophysiology. Prokaryotic origins of mitochondria at the level of membranes and the occurrence of apoptosis in bacteria are presented. Many aspects of ceramide and sphingolipid biology are addressed in this book. Its focus is the metabolism of ceramide in normal and diseased states and the biophysical and biochemical mechanisms governing the bioactivity of these molecules. Sphingolipid research has surged over the past thirty years and this book gathers the recent findings of various aspects of sphingolipid biochemistry. World-renowned scientists from the field of lipid biology, specifically sphingolipid biochemistry, were gathered to write this book. Scholars from most continents of the globe committed to write diligently about their expertise and the newest findings in the relevant fields. This book came to fruition after almost a year and a half of laborious preparation and diligent writings. This book is targeted to the experienced reader who is looking to read about the various aspects of bioactive ceramide signaling, as well as to the newcomer into the field, as the topics are explained in concise yet very informative manner. The authors and editor wish all readers a pleasant time reading this volume, and are adamant that this book will meet all expectations.
