Journey from Cognition to Brain to Gene

Journey from Cognition to Brain to Gene PDF Author: Ursula Bellugi
Publisher: MIT Press
ISBN: 9780262523127
Category : Medical
Languages : en
Pages : 224

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Book Description
A blueprint for the investigation of neurodevelopmental disorders, this book presents the work of a team of scientists using a multidisciplinary, integrated approach to link genes with human behavior. Using Williams syndrome as a model, leading researchers in neuroanatomy, neurocognition, neurophysiology, and molecular genetics have built bridges between disciplines to link higher cognitive functions, their underlying neurobiological bases, and their molecular genetic underpinnings. One of the book's many strengths is that the scientists from each discipline studied the same individuals with Williams syndrome. As the book shows, Williams syndrome is a fascinating disorder because of the "peaks and valleys" among cognitive domains: severe intellectual deficits but remarkably spared and effusive language; specific impairment in spatial construction but great strength in face processing and sociability. By capitalizing on these dissociations in higher cognitive functioning, the book provides a model for the study of brain-behavior relationships as well as for the mapping of brain and behavior phenotypes to the genome and beyond. Contributors Ralph Adolphs, Twyla Alvarez, Lawrence Appelbaum, Ursula Bellugi, Dennis Burian, Xiao-Ning Chen, Michael Chiles, Stephan Eliez, Albert Galaburda, Hanao Hirota, Wendy Jones, Julie Korenberg, Zona Lai, Liz Lichtenberger, Alan Lincoln, Rumiko Matsuoka, Debra Mills, Helen Neville, Judy Reilly, Allan Reiss, Bruce Roe, Marie St. George, J. Eric Schmidtt, Erica Straus

Journey from Cognition to Brain to Gene

Journey from Cognition to Brain to Gene PDF Author: Ursula Bellugi
Publisher: MIT Press
ISBN: 9780262523127
Category : Medical
Languages : en
Pages : 224

Get Book

Book Description
A blueprint for the investigation of neurodevelopmental disorders, this book presents the work of a team of scientists using a multidisciplinary, integrated approach to link genes with human behavior. Using Williams syndrome as a model, leading researchers in neuroanatomy, neurocognition, neurophysiology, and molecular genetics have built bridges between disciplines to link higher cognitive functions, their underlying neurobiological bases, and their molecular genetic underpinnings. One of the book's many strengths is that the scientists from each discipline studied the same individuals with Williams syndrome. As the book shows, Williams syndrome is a fascinating disorder because of the "peaks and valleys" among cognitive domains: severe intellectual deficits but remarkably spared and effusive language; specific impairment in spatial construction but great strength in face processing and sociability. By capitalizing on these dissociations in higher cognitive functioning, the book provides a model for the study of brain-behavior relationships as well as for the mapping of brain and behavior phenotypes to the genome and beyond. Contributors Ralph Adolphs, Twyla Alvarez, Lawrence Appelbaum, Ursula Bellugi, Dennis Burian, Xiao-Ning Chen, Michael Chiles, Stephan Eliez, Albert Galaburda, Hanao Hirota, Wendy Jones, Julie Korenberg, Zona Lai, Liz Lichtenberger, Alan Lincoln, Rumiko Matsuoka, Debra Mills, Helen Neville, Judy Reilly, Allan Reiss, Bruce Roe, Marie St. George, J. Eric Schmidtt, Erica Straus

Genetic Neurocognitive Modeling

Genetic Neurocognitive Modeling PDF Author: Edenilson Brandl
Publisher: Edenilson Brandl
ISBN:
Category : Health & Fitness
Languages : en
Pages : 348

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Book Description
It is with great pleasure that I present this book, "Genetic Neurocognitive Modeling", which represents a deep dive into the fascinating interactions between neuroscience, genetics and cognition. Throughout the pages of this work, we invite the reader to embark on a journey full of discoveries and insights, unraveling the secrets of the complex network that connects our brain, our behavior and our genetic heritage. In this era of accelerated scientific advances, understanding the human mind has been the subject of intense investigation. Through innovative neurocognitive models and genetic studies, we are unlocking the mechanisms underlying how we perceive, think, feel and relate to the world around us. Understanding the influence of genetic factors on brain development and functioning is a crucial step towards unlocking the mysteries of human cognition. This book covers a wide range of relevant and current topics that invite us to explore the frontiers of neuroscience and cognitive genetics. Each chapter is devoted to a specific aspect of this intricate relationship, providing an in-depth look at the most recent advances and the fundamental theories that shape our current knowledge. From the modeling of emotions and emotional regulation to the genetics of creativity and schizophrenia, each topic covered aims to broaden our understanding of cognitive processes and their genetic basis. Along this intellectual journey, we are introduced to groundbreaking research and case studies that help us connect the pieces of this scientific puzzle. The authors, experts in their fields, share their insights and knowledge, shedding light on the latest advances and future prospects. It is an opportunity to inspire and motivate us, not only academics and researchers, but also mental health professionals, educators and anyone interested in understanding the complexity of the human brain. Our intention in writing this book is to provide a comprehensive and accessible overview of genetic neurocognitive modeling, laying a solid foundation for future investigations and stimulating new discoveries. We hope this work inspires and motivates readers to delve into this interdisciplinary field, which is breaking new ground and promoting unprecedented advances in understanding the human mind. Finally, I would like to thank all the authors and contributors who have given their time, knowledge, and passion to this project. Their hard work and dedication are reflected on every page of this book. We hope that this book will be a valuable resource for anyone interested in neuroscience, genetics, and cognition, and that it will advance knowledge in this exciting and ever-evolving field.

Gene Expression to Neurobiology and Behaviour

Gene Expression to Neurobiology and Behaviour PDF Author:
Publisher: Elsevier
ISBN: 0444538852
Category : Science
Languages : en
Pages : 376

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Book Description
How does the genome, interacting with the multi-faceted environment, translate into the development by which the human brain achieves its astonishing, adaptive array of cognitive and behavioral capacities? Why and how does this process sometimes lead to neurodevelopmental disorders with a major, lifelong personal and social impact? This volume of Progress in Brain Research links findings on the structural development of the human brain, the expression of genes in behavioral and cognitive phenotypes, environmental effects on brain development, and developmental processes in perception, action, attention, cognitive control, social cognition, and language, in an attempt to answer these questions. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Neurodevelopmental Disorders: Cognitive Behavioural Phenotypes

Neurodevelopmental Disorders: Cognitive Behavioural Phenotypes PDF Author: Daria Riva
Publisher: John Libbey Eurotext
ISBN: 2742013415
Category : Medical
Languages : en
Pages :

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Book Description
In recent years our approach to neurodevelopmental disorders has undergone extraordinary change. This has resulted from tremendous progress in various different disciplines including developmental neuroscience, behavioural and molecular genetics, and developmental neurobiology, and from the very high quality now achievable in neuroimaging and neurophysiological techniques. This publication aims to provide a concise and interdisciplinary approach to the study of the different cognitive/behavioural phenotypes encountered in a wide range of neurodevelopmental disorders. Starting from methodological, nosographic, and assessment premises, the book deals with selected disorders of a defined but still complex genetic aetiology, and concludes with a description of the neuropsychiatric disorders that are most commonly encountered during development.

Spatial Representation

Spatial Representation PDF Author: Barbara Landau
Publisher: Oxford University Press
ISBN: 0195385373
Category : Medical
Languages : en
Pages : 401

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Book Description
Despite our impression of a seamless spatial world, mature human spatial knowledge is composed of sub-systems, each specialized. This book uses the case of Williams syndrome — a rare genetic deficit - to argue for specialization of function in both normal and unusual development. The evidence suggests a speculative hypothesis linking the genetic deficit to changes in the timing of emergence for different sub-systems. More broadly, the book shows the complexity of spatial cognition, its genetic correlates, and realization in the brain.

The Genetics of Cognitive Neuroscience

The Genetics of Cognitive Neuroscience PDF Author: Terry E. Goldberg
Publisher: Mit Press
ISBN: 9780262013079
Category : Psychology
Languages : en
Pages : 297

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Book Description
A primer on understanding the influence of specific genetic variants on cognition, affective regulation, personality, and central nervous system disorders. It has long been known that aspects of behavior run in families; studies show that characteristics related to cognition, temperament, and all major psychiatric disorders are heritable. This volume offers a primer on understanding the genetic mechanisms of such inherited traits. It proposes a set of tools--a conceptual basis--for critically evaluating recent studies and offers a survey of results from the latest research in the emerging fields of cognitive genetics and imaging genetics. The chapters emphasize fundamental issues regarding the design of experiments, the use of bioinformatic tools, the integration of data from different levels of analysis, and the validity of findings, arguing that associations between genes and cognitive processes must be replicable and placed in a neurobiological context for validation. The Genetics of Cognitive Neuroscience aims to give the reader a working understanding of the influence of specific genetic variants on cognition, affective regulation, personality, and central nervous system disorders. With its emphasis on general methodological points, it will remain a valuable resource in a fast-evolving field. Contributors Kristin L. Bigos, Katherine E. Burdick, Jingshan Chen, Aiden Corvin, Jeffrey L. Cummings, Ian J. Deary, Gary Donahoe, Eco J. C. de Geus, Jin Fan, Erika E. Forbes, John Fossella, Terry E. Goldberg, Ahmad R. Hariri, Lucas Kempf, Anil K. Malhotra, Venkata S. Mattay, Lauren M. McGrath. Kristin K. Nicodemus, Francesco Papaleo, Bruce F. Pennington, Michael I. Posner, Danielle Posthuma, John M. Ringman, Shelley D. Smith, Daniel R. Weinberger, Fengyu Zhang

Child Development and the Brain

Child Development and the Brain PDF Author: Rob Abbott
Publisher: Policy Press
ISBN: 1447355687
Category : Social Science
Languages : en
Pages : 294

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Book Description
This bestselling textbook provides social science students with an accessible introduction to neuroscience and the implications for our understandings of child development, considering the links between brain development and social and cultural issues. Now covering the 0-18+ age range, the new edition critically analyses the relationship between children and young people’s thoughts, behaviours and feelings and the ways in which their developing brains are structured. It includes a new section on emotional development in adolescence, considering the impact of drugs and alcohol on the brain and the role of brain changes in driving risky behaviours. Assuming no prior knowledge of the subject, the text connects the latest scientific knowledge to the practice of understanding and working with children. Incorporating the latest research and debate throughout, the book offers students and practitioners working with children: • case studies showing how brain science is changing practice; • a companion website including self-test questions; • end-of-chapter summaries, further reading and questions to test knowledge; • a glossary of neuroscientific terms.

Cognitive and Behavioral Abnormalities of Pediatric Diseases

Cognitive and Behavioral Abnormalities of Pediatric Diseases PDF Author: Ruth D. Nass
Publisher: Oxford University Press, USA
ISBN: 0195342682
Category : Medical
Languages : en
Pages : 694

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Book Description
This book provides a detailed account of intellectual, other neuropsychological and behavioral manifestations of general pediatric diseases. The conditions discussed include the whole range of pediatric diseases - genetic syndromes, other congenital conditions, metabolic, endocrine, gastrointestinal, infectious, immunologic, toxic, trauma, and neoplastic, as well as sensory disabilities including deafness and blindness. Although the book is not intended to discuss cognitive and behavioral manifestations of conditions usually considered to be primary neurological disease, some of those, including cerebral palsy, muscular dystrophy, myotonic dystrophy and epilepsy, are included. Where possible, a "translational" approach is used, linking the behavioral and cognitive manifestations of these conditions, to the underlying structural, chemical or genetic abnormalities and their effect on the brain, and, in turn, on behavior and cognition. At the same time, included are significant psychosocial factors. Together, those factors have a major effect on patients' performance, including school performance, and on their families. This book is unique in its extensive coverage of the major pediatric conditions and of the detailed neurological, neuropsychological and behavioral aspects of each condition.

International Review of Research in Developmental Disabilities

International Review of Research in Developmental Disabilities PDF Author:
Publisher: Academic Press
ISBN: 0128051779
Category : Psychology
Languages : en
Pages : 314

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Book Description
International Review of Research in Developmental Disabilities provides an ongoing scholarly look at research into the causes, effects, classification systems, and syndromes, etc. of developmental disabilities. Contributors come from wide-ranging perspectives, including genetics, psychology, education, and other health and behavioral sciences. Provides the most recent scholarly research in the study of developmental disabilities Contains a vast range of perspectives, with many topics covered Presents an excellent resource for academic researchers

Neural Circuit and Cognitive Development

Neural Circuit and Cognitive Development PDF Author: Bin Chen
Publisher: Academic Press
ISBN: 0128144122
Category : Psychology
Languages : en
Pages : 670

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Book Description
Neural Circuit and Cognitive Development, Second Edition, the latest release in the Comprehensive Developmental Neuroscience series, provides a much-needed update to underscore the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume is devoted mainly to anatomical and functional development of neural circuits and neural systems and cognitive development. Understanding the critical role these changes play in neurodevelopment provides the ability to explore and elucidate the underlying causes of neurodevelopmental disorders and their effect on cognition. This series is designed to fill the knowledge gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Includes coverage of mechanisms that control the assembly of neural circuits in specific regions of the nervous system and multiple aspects of cognitive development