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Author: G. di Prisco
Publisher: Springer Science & Business Media
ISBN: 8847021111
Category : Science
Languages : en
Pages : 123
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Book Description
This volume comprises selected contributions by internationally renowned researchers and represents the state-of-the-art in the field of hemoglobin function in vertebrates living in extreme and temperate environments. The topics have been covered from several viewpoints, including protein chemistry, molecular biology, and evolution. All the contributions chosen for publication focus on phenotypic and genetic adaptations to changing environmental conditions and on gene expression and regulation. The book provides the reader with an update in this field, which is presently enjoying a true renaissance following developments in recent years of powerful methodologies such as site-directed mutagenesis and discoveries of new roles, for example, as oxygen sensors and in nitric oxide metabolism.
Author: G. di Prisco
Publisher: Springer Science & Business Media
ISBN: 8847021111
Category : Science
Languages : en
Pages : 123
Get Book
Book Description
This volume comprises selected contributions by internationally renowned researchers and represents the state-of-the-art in the field of hemoglobin function in vertebrates living in extreme and temperate environments. The topics have been covered from several viewpoints, including protein chemistry, molecular biology, and evolution. All the contributions chosen for publication focus on phenotypic and genetic adaptations to changing environmental conditions and on gene expression and regulation. The book provides the reader with an update in this field, which is presently enjoying a true renaissance following developments in recent years of powerful methodologies such as site-directed mutagenesis and discoveries of new roles, for example, as oxygen sensors and in nitric oxide metabolism.
Author: Ulrich Hoeger
Publisher: Springer Nature
ISBN: 3030417697
Category : Science
Languages : en
Pages : 527
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Book Description
This book focuses on respiratory proteins, the broad hemoglobin family, as well as the molluscan and arachnid hemocyanins (and their multifunctional roles). Featuring 20 chapters addressing invertebrate and vertebrate respiratory proteins, lipoproteins and other body fluid proteins, and drawing on the editors’ extensive research in the field, it is a valuable addition to the Subcellular Biochemistry book series. The book covers a wide range of topics, including lipoprotein structure and lipid transport; diverse annelid, crustacean and insect defense proteins; and insect and vertebrate immune complexes. It also discusses a number of other proteins, such as the hemerythrins; serum albumin; serum amyloid A; von Willebrand factor and its interaction with factor VIII; and C-reactive protein. Given its scope, the book appeals to biologists, biomedical scientists and clinicians, as well as advanced undergraduates and postgraduates in these disciplines. Available as a printed book and also as an e-book and e-chapters, the fascinating material included is easily accessible.
Author: Roland N. Pittman
Publisher: Biota Publishing
ISBN: 1615047212
Category : Medical
Languages : en
Pages : 117
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Book Description
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Author: Jay F. Storz
Publisher: Oxford University Press, USA
ISBN: 0198810687
Category : Science
Languages : en
Pages : 258
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Book Description
The primary aim of this book is to provide a synthesis of our current understanding of hemoglobin function and evolution, and to illustrate how research on one particular family of proteins has provided general insights into mechanisms of protein evolution and biochemical adaptation. In doing so, it will also promote an appreciation of how mechanistic insights into protein function can enrich our understanding of how evolution works. Reciprocally, it highlights how approaches in evolutionary genetics (such as phylogenetic comparative methods and ancestral sequence reconstruction) can be brought to bear on questions about the functional evolution of proteins. This treatise on the functional evolution of hemoglobin illustrates how research on a single, well-chosen model system can enhance our investigative acuity and bring key conceptual questions into especially sharp focus.
Author: Richard Earl Dickerson
Publisher: Benjamin-Cummings Publishing Company
ISBN:
Category : Hemoglobin
Languages : en
Pages : 194
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Book Description
Author: Jean Lamy
Publisher: Springer Science & Business Media
ISBN: 3642706169
Category : Science
Languages : en
Pages : 186
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Book Description
This volume is one of those published from the proceedings of the invited lectures to the First International Congress of Comparative Physiology and Biochemistry I organized at LI~e (Belgium) in August 1984 under the auspices of the Section of Comparative of the International Union of Biological Sciences. In a Physiology and Biochemistry general foreword to these different volumes, it seems to me appropriate to consider briefly what may be the comparative approach. Living organisms, beyond the diversity of their morphological forms, have evolved a widespread range of basic solutions to cope with the different problems, both organisma! and environmental, with which they are faced. Soon after the turn of the century, some biologists realized that these solutions can be best comprehended In the framework of a comparative approach integrating results of phYSiological and biochemical studies done at the organismic, cellular and molecular levels. The development of this approach amongst both physiologists and biochemists remained, however, extremely slow until recently.
Author: J. Neuwirt
Publisher: Springer Science & Business Media
ISBN: 9401010900
Category : Medical
Languages : en
Pages : 204
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Book Description
Haemoglobin is one of the most important molecules in the animal kingdom. Its function is to carry oxygen to tissues. In lower invertebrates the blood pigment is present in the haemolymph and is not bound in cells. Later in the course of phylo genesis haemoglobin remains associated with cells which produce it and in this form it reaches the peripheral circulation. In higher organisms the haemoglobin production is thus determined by two main factors: haemoglobin synthesis in erythroid cells and the formation of these erythroid cells which depends on cell proliferation in haematopoietic organs. Human haemoglobin is made up of two chains which combine from four different polypeptide chains formed in varying ratios in different periods of the life cycle. During the life span of humans the following haemoglobins are formed: embryonic haemoglobins Gower 1 and 2, foetal haemoglobin F and two adult haemoglobins A and A . E-and IX-chains are part of the embryonic haemoglobins Gower 1 (E4) and 2 Gower 2 (1X2E2). These haemoglobins predominate in embryos during the second month of pregnancy and at the end of the first trimester they are completely re placed by foetal haemoglobin F (~Y2). Adult haemoglobin A consists of two IX and two ~-chains and is the main component of red cells in adults. A relatively small component of red cells accounting for less than 2 % of the total haemo globin, is haemoglobin A2 (1X0).
Author: Guido di Prisco
Publisher: Springer Science & Business Media
ISBN: 3642762174
Category : Science
Languages : en
Pages : 298
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Book Description
Biology of Antarctic Fish presents the most recent findings on the biology of fish in the unique environment of the Antarctic ocean. At present the year-round temperature of the coastal waters is very near -1,87 ° C, the equilibrium temperature of the ice-seawater mixture. This extremely low temperature affects different levels of organization of fish life: individuals, organ systems, cells, organelles, membranes, and molecules. Exploring ecology, evolution, and life history as well as physiology, biochemistry, and molecular biology of Antarctic fish the book describes the mechanisms of cold adaptation at all these levels. It provides material for discussion also for fundamental questions in the field of adaptation to an extreme environment and therefore is of particular interest not only to specialized scientists, but also to those involved in basic and evolutionary biology.
Author: Mikko Nikinmaa
Publisher:
ISBN:
Category : Erythrocytes
Languages : en
Pages : 284
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Book Description
Author: Martin H. Steinberg
Publisher: Cambridge University Press
ISBN: 0521875196
Category : Medical
Languages : en
Pages : 883
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Book Description
Completely revised new edition of the definitive reference on disorders of hemoglobin.
