Handbook of Chiral Chemicals PDF Download
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Author: David Ager
Publisher: CRC Press
ISBN: 1420027301
Category : Medical
Languages : en
Pages : 664
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Book Description
As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. "The Handbook of Chiral Chemicals, Second Edition" highlights the problems associated with the production of chiral compounds on a commercial scale. The handbook fir
Author: David Ager
Publisher: CRC Press
ISBN: 1420027301
Category : Medical
Languages : en
Pages : 664
Get Book
Book Description
As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. "The Handbook of Chiral Chemicals, Second Edition" highlights the problems associated with the production of chiral compounds on a commercial scale. The handbook fir
Author: David Ager
Publisher: CRC Press
ISBN: 9781574446647
Category : Science
Languages : en
Pages : 664
Get Book
Book Description
As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. "The Handbook of Chiral Chemicals, Second Edition" highlights the problems associated with the production of chiral compounds on a commercial scale. The handbook first elaborates upon starting materials obtained from a 'chiral pool', which can be derived from natural products. Then it explains methods and reactions that can introduce or influence stereogenic centers, particularly asymmetric hydrogenations, oxidations, pericyclic reactions, and enzymatic methods.While hydrogenations have been the most widely employed approach for the large-scale synthesis of several commercial compounds, the search for the ideal catalyst has consistently led researchers to enzymes present in biological systems. Several chapters concentrate on understanding how to manipulate enzymes for catalyzing new reactions for taking new substrates. Other significant topics include chiral auxiliaries, chromatographic techniques, enantiomers-specific reactions, and resolution. This second edition updates all its chapters, illustrating the speed of development in this field, and features new chapters that highlight successful approaches in an industrial setting. "The Handbook of Chiral Chemicals, Second Edition" is a guide to advances in the field that result in more efficient and cost-effective synthesis of chiral chemicals.
Author: Dale L. Perry
Publisher: CRC Press
ISBN: 9781439814611
Category : Science
Languages : en
Pages : 0
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Book Description
This updated edition of the Handbook of Inorganic Compounds is the perfect reference for anyone that needs property data for compounds, CASRN numbers for computer or other searches, a consistent tabulation of molecular weights to synthesize inorganic materials on a laboratory scale, or data related to physical and chemical properties. Fully revised, the second edition includes new data on inorganic optical materials, radiation detection inorganics, thermochromic compounds, piezochromic compounds, catalysts, superconductors, and luminescent (fluorescent and phosphorescent) inorganics. Compiled for chemists, chemical engineers, materials scientists, and other scientists, this handbook provides: Basic, essential property data for compounds that they wish to use in their database compilations, research, and applications work American Chemical Society (ACS) Chemical Abstract Registry Numbers (RNs, or CAS numbers) for computer and other searches. An effort has been made to include CAS numbers for both hydrated chemical compounds and their parent anhydrous compounds A tabulation of molecular weights for calculations. In this handbook, molecular weights have been calculated to three decimal places in all cases Textbook and inorganic chemistry resource books The Handbook of Inorganic Compounds: Second Edition consists of data for 3,326 selected gas, liquid, and solid compounds, including representative compounds of several different classes of compounds. Choices of compounds were based on criteria such as inclusion of the compounds in various handbooks of laboratory chemicals, discussion in recent research publications, compounds important to inorganic materials chemistry, and comments of the Advisory Committee guiding the production of the first edition of the handbook.
Author: P.L. Polavarapu
Publisher: Elsevier
ISBN: 0444640282
Category : Science
Languages : en
Pages : 824
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Book Description
Chiral Analysis: Advances in Spectroscopy, Chromatography and Emerging Methods, Second Edition covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals, including chemistry graduate students, analytical chemists, organic chemists, professionals in the pharmaceutical industry, and others with an interest in chirality and chiral analysis. This thoroughly revised second edition covers several new, important areas of chiral analysis that have emerged since the first edition. Three of the new methods provide higher sensitivity than can be realized with the current methods and are expected to become mainstream applications: cavity based methods offer vastly higher sensitivity than conventional polarimetric methods, microwave chiral detection provides unsurpassed sensitivity for identifying diastereomers, and the rotating electric field method offers a competing new approach for the separation of enantiomers. Another topic, chirality in extraterrestrial life, has not been discussed in any other book and is important for understanding the origin of life. Offers the only book to cover both spectroscopic and separation methods in a single volume Provides an up-to-date and detailed review of the various techniques available, including new techniques that have emerged since the first edition Includes contributions from a range of leading experts in the field, now edited by award-winning chirality researcher Prasad Polavarapu
Author: Michael C. Pirrung
Publisher: Academic Press
ISBN: 9780128095812
Category : Science
Languages : en
Pages : 0
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Book Description
Handbook of Synthetic Organic Chemistry, Second Edition updates and expands the author's popular 2007 work, Synthetic Organic Chemist's Companion. This new handbook provides valuable, practical guidance; incorporates corrections, and includes coverage on important topics, such as lyophylization, crystallization, precipitation, HPLC detectors, gases, and microwave reactions. The book maintains the useful organization of the author's earlier work, beginning with a basic overview and walking through every practical step of the process of organic synthesis, from reagents, solvents, and temperature control, to documentation, implementation, purification, and analytical methods for the product. From planning and setting up reactions, to recording them, the book provides insight and valuable guidance into every step of the process.
Author: Robert H. Grubbs
Publisher: John Wiley & Sons
ISBN: 3527694021
Category : Science
Languages : en
Pages : 744
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Book Description
The second edition of the "go-to" reference in this field is completely updated and features more than 80% new content, with emphasis on new developments in the field, especially in industrial applications. No other book covers the topic in such a comprehensive manner and in such high quality. Edited by the Nobel laureate R. H. Grubbs and D. J. O´Leary, Volume 2 of the 3-volume work focusses on applications in organic synthesis. With a list of contributors that reads like a "Who's-Who" of metathesis, this is an indispensable one-stop reference for chemists in academia and industry. View the set here - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527334246.html Other available volumes: Volume 1: Catalyst Development and Mechanism, Editors: R. H. Grubbs and A. G. Wenzel - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339485.html Volume 3: Polymer Synthesis, Editors: R. H. Grubbs and E. Khosravi - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339507.html
Author: Wenyi Zhao (Chemist)
Publisher:
ISBN: 9781032264615
Category : Drugs
Languages : en
Pages : 0
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Book Description
"This fully updated second edition reflects the significant changes in process chemistry since the first edition and includes more common process issues such as safety, cost, robustness, and environmental impact. Some areas have made notable progress such as process safety, stereochemistry, new reagents and reagent surrogates. Forty years ago there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies"--
Author: Wenyi Zhao
Publisher: CRC Press
ISBN: 1000859053
Category : Science
Languages : en
Pages : 938
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Book Description
This fully updated second edition reflects the significant changes in process chemistry since the first edition and includes more common process issues such as safety, cost, robustness, and environmental impact. Some areas have made notable progress such as process safety, stereochemistry, new reagents and reagent surrogates. Forty years ago there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies. Features: This unique volume now in its second edition is designed to provide readers with an unprecedented strategy and approach which will help chemists and graduate students develop chemical processes in an efficient manner. Promotes an industrial mindset concerning safety and commercial viability when developing methods. The author discusses development strategies with case studies and experimental procedures. Focuses on mechanism-guided process development which provides readers with practical strategies and approaches. Addresses more common process issues such as safety, cost, robustness, and environmental impact. This book provides a new direction for scientists, researchers, and students in materials science and polymer chemistry who seek to better understand the chemistry behind conducting polymers and improve their performance for use in advanced energy applications.
Author: Hans R. Kricheldorf
Publisher: CRC Press
ISBN: 1420030590
Category : Science
Languages : en
Pages : 984
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Book Description
An in-depth review of important preparative methods for the synthesis and chemical modification of polymers, this authoritative second edition examines the advantages and limitations of various polymerization applications and procedures. It features new approaches and innovative strategies from the most prominent industry and academic laboratories,
Author: Thomas J. Bruno
Publisher: CRC Press
ISBN: 9780849315732
Category : Science
Languages : en
Pages : 688
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Book Description
If you are a researcher in organic chemistry, chemical engineering, pharmaceutical science, forensics, or environmental science, you make routine use of chemical analysis. And like its best-selling predecessor was, the Handbook of Basic Tables for Chemical Analysis, Second Edition is your one-stop source for the information needed to design chemical analyses. Here's what is new in the Second Edition: New chapters on solutions, electroanalytical methods, electrophoresis, and laboratory safety An expanded section on gas chromatography that includes data on compounds that attack common detectors New information on detector optimization An updated section on high performance liquid chromatography that provides the most recent chiral stationary phases, detector information, and revised solvent tables Updated information on the most useful "wet" chemistry methods Enlarged section of Miscellaneous Tables Going far beyond the landmark first edition in terms of scope and applications, the second edition provides current and updated data culled from a wide range of resources and consolidated into a concise yet easy-to-use format. The book's laser-like focus on core information gives you the knowledge you need when you need it - at the decision point.
