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Author: Douglas Wahlsten
Publisher: Academic Press
ISBN: 0128128321
Category : Science
Languages : en
Pages : 300
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Book Description
Genes, Brain Function, and Behavior offers a concise description of the nervous system that processes sensory input and initiates motor movements. It reviews how behaviors are defined and measured, and how experts decide when a behavior is perturbed and in need of treatment. Behavioral disorders that are clearly related to a defect in a specific gene are reviewed, and the challenges of understanding complex traits such as intelligence, autism and schizophrenia that involve numerous genes and environmental factors are explored. New methods of altering genes offer hope for treating or even preventing difficulties that arise in our genes. This book explains what genes are, what they do in the nervous system, and how this impacts both brain function and behavior. Presents essential background, facts, and terminology about genes, brain function, and behavior Builds clear explanations on this solid foundation while minimizing technical jargon Explores in depth several single-gene and chromosomal neurological disorders Derives lessons from these clear examples and highlights key lessons in boxes Examines the intricacies of complex traits that involve multiple genetic and environmental factors by applying lessons from simpler disorders Explains diagnosis and definition Includes a companion website with Powerpoint slides and images for each chapter for instructors and links to resources
Author: Douglas Wahlsten
Publisher: Academic Press
ISBN: 0128128321
Category : Science
Languages : en
Pages : 300
Get Book
Book Description
Genes, Brain Function, and Behavior offers a concise description of the nervous system that processes sensory input and initiates motor movements. It reviews how behaviors are defined and measured, and how experts decide when a behavior is perturbed and in need of treatment. Behavioral disorders that are clearly related to a defect in a specific gene are reviewed, and the challenges of understanding complex traits such as intelligence, autism and schizophrenia that involve numerous genes and environmental factors are explored. New methods of altering genes offer hope for treating or even preventing difficulties that arise in our genes. This book explains what genes are, what they do in the nervous system, and how this impacts both brain function and behavior. Presents essential background, facts, and terminology about genes, brain function, and behavior Builds clear explanations on this solid foundation while minimizing technical jargon Explores in depth several single-gene and chromosomal neurological disorders Derives lessons from these clear examples and highlights key lessons in boxes Examines the intricacies of complex traits that involve multiple genetic and environmental factors by applying lessons from simpler disorders Explains diagnosis and definition Includes a companion website with Powerpoint slides and images for each chapter for instructors and links to resources
Author: Robert T. Gerlai
Publisher: Academic Press
ISBN: 0128041161
Category : Mathematics
Languages : en
Pages : 710
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Book Description
Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior Written and edited by leading international experts
Author:
Publisher: Elsevier
ISBN: 0444538852
Category : Science
Languages : en
Pages : 376
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Book Description
How does the genome, interacting with the multi-faceted environment, translate into the development by which the human brain achieves its astonishing, adaptive array of cognitive and behavioral capacities? Why and how does this process sometimes lead to neurodevelopmental disorders with a major, lifelong personal and social impact? This volume of Progress in Brain Research links findings on the structural development of the human brain, the expression of genes in behavioral and cognitive phenotypes, environmental effects on brain development, and developmental processes in perception, action, attention, cognitive control, social cognition, and language, in an attempt to answer these questions. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Author: Deborah Finkel
Publisher: Springer Science & Business Media
ISBN: 1461474477
Category : Psychology
Languages : en
Pages : 300
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Book Description
Along with psychopathology, cognition has been one of the primary phenotypic focal points of the field of behavior genetics since its inception. Francis Galton’s 1874 examination of eminent families in Britain was among the earliest attempts to investigate whether cognitive achievements run in families. This volume presents current methodologies for understanding cognitive abilities that move beyond the outdated nature vs. nurture paradigm. Recent advances in both collection and statistical modeling of twin data, particularly longitudinal twin data, make this an especially advantageous moment to produce a work that presents a collection of the groundbreaking research on cognitive abilities across the lifespan. This volume presents an overview of the current state of quantitative and molecular genetic investigations into the many facets of cognitive performance and functioning across the lifespan.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309069882
Category : Social Science
Languages : en
Pages : 610
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Book Description
How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.
Author: Dr Jonathan D Bolen
Publisher: Ashgate Publishing, Ltd.
ISBN: 140949795X
Category : Social Science
Languages : en
Pages : 233
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Book Description
The main feature of this work is that it explores criminal behavior from all aspects of Tinbergen's Four Questions. Rather than focusing on a single theoretical point of view, this book examines the neurobiology of crime from a biosocial perspective. It suggests that it is necessary to understand some genetics and neuroscience in order to appreciate and apply relevant concepts to criminological issues. Presenting up-to-date information on the circuitry of the brain, the authors explore and examine a variety of characteristics, traits and behavioral syndromes related to criminal behavior such as ADHD, intelligence, gender, the age-crime curve, schizophrenia, psychopathy, violence and substance abuse. This book brings together the sociological tradition with the latest knowledge the neurosciences have to offer and conveys biological information in an accessible and understanding way. It will be of interest to scholars in the field and to professional criminologists.
Author: William R. Clark
Publisher: Oxford University Press
ISBN: 0190292318
Category : Science
Languages : en
Pages : 336
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Book Description
Books such as Richard Dawkins's The Selfish Gene have aroused fierce controversy by arguing for the powerful influence of genes on human behavior. But are we entirely at the mercy of our chromosomes? In Are We Hardwired?, scientists William R. Clark and Michael Grunstein say the answer is both yes--and no. The power and fascination of Are We Hardwired? lie in their explanation of that deceptively simple answer. Using eye-opening examples of genetically identical twins who, though raised in different families, have had remarkably parallel lives, the authors show that indeed roughly half of human behavior can be accounted for by DNA. But the picture is quite complicated. Clark and Grunstein take us on a tour of modern genetics and behavioral science, revealing that few elements of behavior depend upon a single gene; complexes of genes, often across chromosomes, drive most of our heredity-based actions. To illustrate this point, they examine the genetic basis, and quirks, of individual behavioral traits--including aggression, sexuality, mental function, eating disorders, alcoholism, and drug abuse. They show that genes and environment are not opposing forces; heredity shapes how we interpret our surroundings, which in turn changes the very structure of our brain. Clearly we are not simply puppets of either influence. Perhaps most interesting, the book suggests that the source of our ability to choose, to act unexpectedly, may lie in the chaos principle: the most minute differences during activation of a single neuron may lead to utterly unpredictable actions. This masterful account of the nature-nurture controversy--at once provocative and informative--answers some of our oldest questions in unexpected new ways
Author: Wim E. Crusio
Publisher: Elsevier
ISBN: 9780080536866
Category : Psychology
Languages : en
Pages : 962
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Book Description
The book gives a broad overview of recombinant DNA techniques for the behavioral neuroscientist, with illustrative examples of applications. Species covered include rodents (mainly mice), Drosophila melanogaster, Caenorhabditis elegans and Danio rerio. Experimental techniques required to characterize the behavioral phenotypes of mutant animals is provided. Several aspects of novel molecular-genetic techniques are overviewed and possible research strategies are explained. The sections of the book start with general descriptions of techniques followed by illustrative examples. It is divided into six sections. Section 1, bioinformatics and genomics research. Section 2, top-down strategies, where the researcher starts with the phenotype and then analyzes the associated genes; bottom-up strategies, where the physiological chain leading to a phenotype is analyzed starting from the gene product. Section 3, transgenic approaches in rodents including overexpressing foreign genes and gene-targeting; systemic manipulation approaches directly targeting the central nervous system and methods used with invertebrates. Section 4, methods used to evaluate relevant behavioral phenotypes, including learning and aggression. Section 5, examples on molecular brain research in man. Section 6, ethical aspects of research in this field.
Author: Yong-Kyu Kim
Publisher: Springer Science & Business Media
ISBN: 0387767274
Category : Medical
Languages : en
Pages : 557
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Book Description
This handbook provides research guidelines to study roles of the genes and other factors involved in a variety of complex behaviors. Utilizing methodologies and theories commonly used in behavior genetics, each chapter features an overview of the selected topic, current issues, as well as current and future research.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309120926
Category : Science
Languages : en
Pages : 90
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Book Description
Neuroscience has made phenomenal advances over the past 50 years and the pace of discovery continues to accelerate. On June 25, 2008, the Institute of Medicine (IOM) Forum on Neuroscience and Nervous System Disorders hosted more than 70 of the leading neuroscientists in the world, for a workshop titled "From Molecules to Minds: Challenges for the 21st Century." The objective of the workshop was to explore a set of common goals or "Grand Challenges" posed by participants that could inspire and rally both the scientific community and the public to consider the possibilities for neuroscience in the 21st century. The progress of the past in combination with new tools and techniques, such as neuroimaging and molecular biology, has positioned neuroscience on the cusp of even greater transformational progress in our understanding of the brain and how its inner workings result in mental activity. This workshop summary highlights the important issues and challenges facing the field of neuroscience as presented to those in attendance at the workshop, as well as the subsequent discussion that resulted. As a result, three overarching Grand Challenges emerged: How does the brain work and produce mental activity? How does physical activity in the brain give rise to thought, emotion, and behavior? How does the interplay of biology and experience shape our brains and make us who we are today? How do we keep our brains healthy? How do we protect, restore, or enhance the functioning of our brains as we age?
