Fundamentals of Protein Structure and Function

Fundamentals of Protein Structure and Function PDF Author: Engelbert Buxbaum
Publisher: Springer
ISBN: 331919920X
Category : Science
Languages : en
Pages : 521

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Book Description
This book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. This leads to a discussion how misfolding of proteins causes diseases like cancer, various encephalopathies, or diabetes. Enzymology and modern concepts of enzyme kinetics are then introduced, taking into account the physiological, pharmacological and medical significance of this often neglected topic. This is followed by thorough coverage of hæmoglobin and myoglobin, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins to various cell compartments and solute transport across biological membranes. Proteins in the laboratory are also covered, including a detailed description of the purification and determination of proteins, as well as their characterisation for size and shape, structure and molecular interactions. The book emphasises the link between protein structure, physiological function and medical significance. This book can be used for graduate and advanced undergraduate classes covering protein structure and function and as an introductory text for researchers in protein biochemistry, molecular and cell biology, chemistry, biophysics, biomedicine and related courses. About the author: Dr. Buxbaum is a biochemist with interest in enzymology and protein science. He has been working on the biochemistry of membrane transport proteins for nearly thirty years and has taught courses in biochemistry and biomedicine at several universities.

Fundamentals of Protein Structure and Function

Fundamentals of Protein Structure and Function PDF Author: Engelbert Buxbaum
Publisher: Springer
ISBN: 331919920X
Category : Science
Languages : en
Pages : 521

Get Book

Book Description
This book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. This leads to a discussion how misfolding of proteins causes diseases like cancer, various encephalopathies, or diabetes. Enzymology and modern concepts of enzyme kinetics are then introduced, taking into account the physiological, pharmacological and medical significance of this often neglected topic. This is followed by thorough coverage of hæmoglobin and myoglobin, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins to various cell compartments and solute transport across biological membranes. Proteins in the laboratory are also covered, including a detailed description of the purification and determination of proteins, as well as their characterisation for size and shape, structure and molecular interactions. The book emphasises the link between protein structure, physiological function and medical significance. This book can be used for graduate and advanced undergraduate classes covering protein structure and function and as an introductory text for researchers in protein biochemistry, molecular and cell biology, chemistry, biophysics, biomedicine and related courses. About the author: Dr. Buxbaum is a biochemist with interest in enzymology and protein science. He has been working on the biochemistry of membrane transport proteins for nearly thirty years and has taught courses in biochemistry and biomedicine at several universities.

Fundamentals of Protein Structure and Function

Fundamentals of Protein Structure and Function PDF Author: Engelbert Buxbaum
Publisher: Springer
ISBN: 9783319792903
Category : Science
Languages : en
Pages : 0

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Book Description
This book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. This leads to a discussion how misfolding of proteins causes diseases like cancer, various encephalopathies, or diabetes. Enzymology and modern concepts of enzyme kinetics are then introduced, taking into account the physiological, pharmacological and medical significance of this often neglected topic. This is followed by thorough coverage of hæmoglobin and myoglobin, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins to various cell compartments and solute transport across biological membranes. Proteins in the laboratory are also covered, including a detailed description of the purification and determination of proteins, as well as their characterisation for size and shape, structure and molecular interactions. The book emphasises the link between protein structure, physiological function and medical significance. This book can be used for graduate and advanced undergraduate classes covering protein structure and function and as an introductory text for researchers in protein biochemistry, molecular and cell biology, chemistry, biophysics, biomedicine and related courses. About the author: Dr. Buxbaum is a biochemist with interest in enzymology and protein science. He has been working on the biochemistry of membrane transport proteins for nearly thirty years and has taught courses in biochemistry and biomedicine at several universities.

Protein Structure and Function

Protein Structure and Function PDF Author: Gregory A. Petsko
Publisher: New Science Press
ISBN: 0878936637
Category : Proteins
Languages : en
Pages : 220

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Book Description
Each title in the 'Primers in Biology' series is constructed on a modular principle that is intended to make them easy to teach from, to learn from, and to use for reference.

Fundamentals of Molecular Structural Biology

Fundamentals of Molecular Structural Biology PDF Author: Subrata Pal
Publisher: Academic Press
ISBN: 012814856X
Category : Science
Languages : en
Pages : 518

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Book Description
Fundamentals of Molecular Structural Biology reviews the mathematical and physical foundations of molecular structural biology. Based on these fundamental concepts, it then describes molecular structure and explains basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an adjacent field often require a "fundamentals" book to get them up-to-speed on the foundations of a particular field. This book fills that niche. Provides a current and easily digestible resource on molecular structural biology, discussing both foundations and the latest advances Addresses critical issues surrounding macromolecular structures, such as structure-based drug discovery, single-particle analysis, computational molecular biology/molecular dynamic simulation, cell signaling and immune response, macromolecular assemblies, and systems biology Presents discussions that ultimately lead the reader toward a more detailed understanding of the basis and origin of disease

Fundamentals of Protein NMR Spectroscopy

Fundamentals of Protein NMR Spectroscopy PDF Author: Gordon S. Rule
Publisher: Springer Science & Business Media
ISBN: 1402035004
Category : Science
Languages : en
Pages : 543

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Book Description
NMR spectroscopy has proven to be a powerful technique to study the structure and dynamics of biological macromolecules. Fundamentals of Protein NMR Spectroscopy is a comprehensive textbook that guides the reader from a basic understanding of the phenomenological properties of magnetic resonance to the application and interpretation of modern multi-dimensional NMR experiments on 15N/13C-labeled proteins. Beginning with elementary quantum mechanics, a set of practical rules is presented and used to describe many commonly employed multi-dimensional, multi-nuclear NMR pulse sequences. A modular analysis of NMR pulse sequence building blocks also provides a basis for understanding and developing novel pulse programs. This text not only covers topics from chemical shift assignment to protein structure refinement, as well as the analysis of protein dynamics and chemical kinetics, but also provides a practical guide to many aspects of modern spectrometer hardware, sample preparation, experimental set-up, and data processing. End of chapter exercises are included to emphasize important concepts. Fundamentals of Protein NMR Spectroscopy not only offer students a systematic, in-depth, understanding of modern NMR spectroscopy and its application to biomolecular systems, but will also be a useful reference for the experienced investigator.

Fundamentals of Protein Structure and Function

Fundamentals of Protein Structure and Function PDF Author: Engelbert Buxbaum
Publisher: Springer
ISBN: 9780387508047
Category : Science
Languages : en
Pages : 0

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Book Description
The textbook is clearly written, and is suitable for advanced students, e.g. during their master and PhD course time. It is very suited also for postdocs and young scientists as a textbook if they change fields in their research. The textbook represents a thorough and detailed description of the topics in each of the chapters. As the book selects very important topics of present fundamental research and relevant in medical biochemistry, it can supplement any of the text books in biochemistry and basic medicine already on the market. The textbook is clearly written, and is suitable for advanced students, e.g. during their master and PhD course time. It is very suited also for postdocs and young scientists as a textbook if they change fields in their research. The textbook represents a thorough and detailed description of the topics in each of the chapters. As the book selects very important topics of present fundamental research and relevant in medical biochemistry, it can supplement any of the text books in biochemistry and basic medicine already on the market.

Introduction to Protein Structure

Introduction to Protein Structure PDF Author: Carl Ivar Branden
Publisher: Garland Science
ISBN: 1136969896
Category : Science
Languages : en
Pages : 424

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Book Description
The VitalBook e-book of Introduction to Protein Structure, Second Edition is inly available in the US and Canada at the present time. To purchase or rent please visit http://store.vitalsource.com/show/9780815323051Introduction to Protein Structure provides an account of the principles of protein structure, with examples of key proteins in their bio

Introduction to Protein Science

Introduction to Protein Science PDF Author: Arthur Lesk
Publisher: Oxford University Press
ISBN: 0199541302
Category : Education
Languages : en
Pages : 476

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Book Description
Starting by describing the structure of proteins and explaining how these structures can be studied, this book goes on to illustrate the wide range of protein functions by showing how the shape of a protein is intimately linked to its function.

Fundamentals of Protein Biotechnology

Fundamentals of Protein Biotechnology PDF Author: Stein
Publisher: CRC Press
ISBN: 1351446363
Category : Medical
Languages : en
Pages : 328

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Book Description
Fills a gap between the existing studies of proteins, which tend to be highly technical and geared toward the practicing protein chemist, and biochemistry textbooks, which focus on general principles. Scientists cover a dozen topics by presenting fundamental principles, an overview, and the practica

Principles of Biology

Principles of Biology PDF Author: Lisa Bartee
Publisher:
ISBN: 9781636350417
Category :
Languages : en
Pages :

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Book Description
The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.