Experimental Models for Renal Diseases

Experimental Models for Renal Diseases PDF Author: G.A. Herrera
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805595387
Category : Medical
Languages : en
Pages : 382

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Book Description
Our understanding of the pathogenesis of renal diseases and the ability to accurately classify and diagnose them has improved considerably over the last two decades. Until now, however, this information has not been available in a single, up-to-date and succinct yet comprehensive source. The publication at hand aims at filling this gap, condensing a vast amount of information into easily accessible chapters.After a discussion of basic concepts and principles of renal tissue reactions to injurious agents using a specific cell/compartment approach, a multitude of disorders are looked at, including renal interstitial fibrosis, glomerulosclerosis, various forms of glomerulonephritis and nephropathy, amyloidosis and renal Fanconi syndrome. Some of the chapters address controversial subjects, reporting the current situation and showing areas of future potential research interest. At the end of many of the contributions, a summary is provided, often in the form of a chart to facilitate the understanding of the information and to make it most useful for didactic purposes.This book is intended for students of various disciplines, as well as clinicians and investigators and all those trying to correlate basic research information with clinical issues.

Experimental Models for Renal Diseases

Experimental Models for Renal Diseases PDF Author: G.A. Herrera
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805595387
Category : Medical
Languages : en
Pages : 382

Get Book

Book Description
Our understanding of the pathogenesis of renal diseases and the ability to accurately classify and diagnose them has improved considerably over the last two decades. Until now, however, this information has not been available in a single, up-to-date and succinct yet comprehensive source. The publication at hand aims at filling this gap, condensing a vast amount of information into easily accessible chapters.After a discussion of basic concepts and principles of renal tissue reactions to injurious agents using a specific cell/compartment approach, a multitude of disorders are looked at, including renal interstitial fibrosis, glomerulosclerosis, various forms of glomerulonephritis and nephropathy, amyloidosis and renal Fanconi syndrome. Some of the chapters address controversial subjects, reporting the current situation and showing areas of future potential research interest. At the end of many of the contributions, a summary is provided, often in the form of a chart to facilitate the understanding of the information and to make it most useful for didactic purposes.This book is intended for students of various disciplines, as well as clinicians and investigators and all those trying to correlate basic research information with clinical issues.

Handbook of Animal Models of Renal Failure

Handbook of Animal Models of Renal Failure PDF Author: Stephen R. Ash
Publisher: CRC Press
ISBN: 1351081462
Category : Medical
Languages : en
Pages : 230

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Book Description
This text presents a variety of methods of creation of renal failure, by the author‘s experience in the study and support of laboratory animal models of renal failure. This text also discusses three studies on the mechanisms of renal damage and renal failure in animal models.

Preclinical MRI of the Kidney

Preclinical MRI of the Kidney PDF Author: Andreas Pohlmann
Publisher: Humana
ISBN: 9781071609804
Category :
Languages : en
Pages : 0

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Book Description
Preface... Table of Contents... Contributing Authors... Part I Introduction 1. Recommendations for Preclinical Renal MRI: A Comprehensive Open-Access Protocol Collection to Improve Training, Reproducibility, and Comparability of Studies Andreas Pohlmann, Susan J. Back, Andrea Fekete, Iris Friedli, Stefanie Hectors, Neil Peter Jerome, Min-Chi Ku, Dario Livio Longo, Martin Meier, Jason M. Millward, João S. Periquito, Erdmann Seeliger, Suraj D. Serai, Sonia Waiczies, Steven Sourbron, Christoffer Laustsen, and Thoralf Niendorf Part II Animal Models, Preparation, Monitoring, and Physiological Interventions 2. Animal Models of Renal Pathophysiology and Disease Adam Hosszu, Tamas Kaucsar, Erdmann Seeliger, and Andrea Fekete 3. Preparation and Monitoring of Small Animals in Renal MRI Tamas Kaucsar, Adam Hosszu, Erdmann Seeliger, Henning M. Reimann, and Andrea Fekete 4. Reversible (Patho-)Physiologically Relevant Test Interventions: Rationale and Examples Kathleen Cantow, Mechthild Ladwig-Wiegard, Bert Flemming, Andrea Fekete, Adam Hosszu, Erdmann Seeliger 5. Preparation of Ex Vivo Rodent Phantoms for Developing, Testing, and Training MR Imaging of the Kidney and Other Organs Jason M. Millward, João S. Periquito, Paula Ramos Delgado, Christian Prinz, Thoralf Niendorf, and Sonia Waiczies Part III Basic Concepts of Measurement Techniques 6. Quantitative Assessment of Renal Perfusion and Oxygenation by Invasive Probes: Basic Concepts Kathleen Cantow, Roger G. Evans, Dirk Grosenick, Thomas Gladytz, Thoralf Niendorf, Bert Flemming, and Erdmann Seeliger 7. Ultrasound and Photoacoustic Imaging of the Kidney: Basic Concepts and Protocols Sandra Meyer, Dieter Fuchs, and Martin Meier 8. Hardware Considerations for Preclinical Magnetic Resonance of the Kidney Paula Ramos Delgado, Ekkehard Küstermann, André Kühne, Jason M. Millward, Thoralf Niendorf, Andreas Pohlmann, and Martin Meier 9. MRI Mapping of Renal T1: Basic Concept Stefanie Hectors, Sabrina Doblas, Philippe Garteiser, Gwenaël Pagé, Bernard E. Van Beers, John C. Waterton, and Octavia Bane 10. MRI Mapping of the Blood Oxygenation Sensitive Parameter T2* in the Kidney: Basic Concept Lu-Ping Li, Bradley Hack, Erdmann Seeliger, and Pottumarthi V. Prasad 11. Renal Diffusion Weighted Imaging (DWI) for Apparent Diffusion Coefficient (ADC), Intra Voxel Incoherent Motion (IVIM), and Diffusion Tensor Imaging (DTI): Basic Concept Neil Peter Jerome, Anna Caroli, and Alexandra Ljimani 12. Dynamic Contrast Enhancement (DCE)-MRI Derived Renal Perfusion and Filtration: Basic Concepts Michael Pedersen, Pietro Irrera, Walter Dastrù, Frank G. Zöllner, Kevin M. Bennett, Scott C. Beeman, G. Larry Bretthorst, Joel R. Garbow, and Dario Livio Longo 13. Non-Invasive Renal Perfusion Measurement Using Arterial Spin Labelling (ASL) MRI: Basic Concept Min-Chi Ku, María A. Fernández-Seara, Frank Kober, and Thoralf Niendorf 14. Renal pH Imaging Using Chemical Exchange Saturation Transfer (CEST)-MRI: Basic Concepts Dario Livio Longo, Pietro Irrera, Lorena Consolino, Phillip Zhe Sun, and Michael T. McMahon 15. Sodium (23Na) MRI of the Kidney: Basic Concept James T. Grist, Esben Søvsø Hansen, Frank G. Zöllner, and Christoffer Laustsen 16. Hyperpolarized Carbon (13C) MRI of the Kidneys: Basic Concepts Cornelius von Morze, Galen D. Reed, Zhen J. Wang, Michael A. Ohliger, and Christoffer Laustsen 17. Functional Imaging Using Fluorine (19F) MR Methods: Basic Concepts Sonia Waiczies, Christian Prinz, Ludger Starke, Jason M. Millward, Paula Ramos Delgado, Jens Rosenberg, Marc Nazaré, Helmar Waiczies, Andreas Pohlmann, and Thoralf Niendorf 18. MR Elastography of the Abdomen: Basic Concepts Suraj D. Serai and Meng Yin Part IV Experimental Protocols 19. Monitoring Renal H

Experimental and Genetic Rat Models of Chronic Renal Failure

Experimental and Genetic Rat Models of Chronic Renal Failure PDF Author: Norbert Gretz
Publisher: S Karger Ag
ISBN: 9783805554992
Category : Medical
Languages : en
Pages : 0

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Book Description


Kidney Research

Kidney Research PDF Author: Tim D. Hewitson
Publisher: Humana
ISBN: 9781493956401
Category : Science
Languages : en
Pages : 276

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Book Description
As the expense of treating a growing number of end-stage kidney disease patients increases, greater attention has been paid to prevention and early treatment. The study of renal disease, however, suffers due to the complex nature of renal anatomy and physiology and the plethora of different cell types found in the kidney. In Kidney Research: Experimental Protocols, top experts in the field seek to aid researchers by providing a number of specialized techniques developed to examine this intricate system. Through both well-established and novel methods, this volume explores the preparation and culture of the main cell types used to study renal disease mechanisms, the common animal models used to mimic the various forms of human renal disease, and specific applications and techniques used in vivo and in vitro. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters contain step-by-step, readily reproducible laboratory protocols, lists of the necessary materials and reagents, and tips on troubleshooting and avoiding known pitfalls. Essential and cutting-edge, Kidney Research: Experimental Protocols delivers invaluable guidance to new and experienced laboratory researchers delving into the sophisticated study of the kidney.

Podocytopathy

Podocytopathy PDF Author: Z.-H. Liui
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318026514
Category : Medical
Languages : en
Pages : 277

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Book Description
The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.

International Review of Experimental Pathology

International Review of Experimental Pathology PDF Author: G. W. Richter
Publisher: Academic Press
ISBN: 1483281701
Category : Health & Fitness
Languages : en
Pages : 410

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Book Description
International Review of Experimental Pathology, Volume 30, is organized around the theme of renal disease. The choice of renal disease reflects both the author’s personal interest and the realization that there is a need for such a collection of reviews in this area. There are many new books on renal pathology, but almost all have a clinical rather than experimental orientation. The book opens with a chapter on the pathogenesis of experimentally induced renal papillary necrosis and upper urothelial carcinoma. Subsequent chapters deal with the use of cell cultures in the study of renal diseases; mechanisms of cyclosporine nephrotoxicity in humans and animal systems; spontaneously occurring renal diseases in laboratory animals; and the use of video microscopy to define the reactivity of the renal microvasculature and the hydraulic permeability of the glomerular capillaries. This book will be of interest to a diverse group of readers interested in renal disease. This broad spectrum of potential readership is reflected in the list of contributors which includes, in addition to pathologists, nephrologists, anatomists, veterinarians, and experimental chemists. This volume will also be of interest to transplant surgeons and to pediatricians specializing in renal disease.

Diabetic Kidney Disease

Diabetic Kidney Disease PDF Author: Takashi Wada
Publisher: Springer
ISBN: 9789811593031
Category : Medical
Languages : en
Pages : 0

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Book Description
This book presents the latest information on the clinical-pathological features of diabetic kidney disease. The data included is based on a cohort study of biopsy-proven diabetic nephropathy patients and nephrosclerosis patients, who were observed over a long term, and on the long-term registry for diabetic nephropathy (diabetic kidney disease) in Japan. It provides a clinical-pathological axis in clinical settings, including differential pathological/clinical diagnoses of CKD in diabetic patients (e.g. the presence of “classic” diabetic nephropathy and/or nephrosclerosis and/or other primary kidney diseases). The abundant biopsy specimens with long-term medical records provide a detailed pathological and clinical description. The book also includes urine-sample data for developing and validating possible candidates for novel biomarkers for diabetic kidney disease.Many countries, including Japan, have ageing populations, in which nephrosclerosis contributes to the progression of kidney lesions in patients with diabetic kidney disease. As such, a comparison of a diabetic nephropathy cohort with nephrosclerosis is indispensable to offer better treatments.This comprehensive and informative book is an indispensible reference resource for all physicians and researchers in the field of nephrology and diabetes.

Heptinstall's Pathology of the Kidney

Heptinstall's Pathology of the Kidney PDF Author: J. Charles Jennette
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781747509
Category : Medical
Languages : en
Pages : 930

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Book Description
Experts in the field of renal disease offer careful pathologic descriptions, appropriate clinical correlations, and extensive discussions on causes and pathogenesis to clarify the clinicians understanding and help facilitate easy, accurate diagnosis. This updated edition features hundreds of razor-sharp illustrations along with more international contributors than before.

Hemodialysis

Hemodialysis PDF Author: Claudio Ronco
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805585667
Category : Medical
Languages : en
Pages : 289

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Book Description
Ronco and Cruz (both Dept. of Nephrology, San Bortolo Hospital, Vicenza, Italy) present a collection of 36 articles focusing on the physiological aspects of hemodialysis treatments as well as practical questions in the dialysis unit. Originally created as a supplement to the lectures presented at the 17th Annual International Course on Hemodialysis, a three-day event held in Vicenza, Italy, the text provides a valuable reference for the clinician interested in keeping up on developments in the field of hemodialysis. Thirty-six contributions by some 80 international academics, researchers, and practitioners are organized into ten sections covering dialysis technology, vascular access, epidemiology and practice, inflammation, fluid management, uremic toxicity, treatment efficacy, advanced techniques, calcium/phosphate homeostasis, and correction of anemia.