Dupuytren Disease and Related Diseases - The Cutting Edge

Dupuytren Disease and Related Diseases - The Cutting Edge PDF Author: Paul M. N. Werker
Publisher: Springer
ISBN: 3319321994
Category : Medical
Languages : en
Pages : 450

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Book Description
In this book, leading international experts showcase the latest advances in research into Dupuytren disease and its clinical management. The coverage spans all relevant specialties, including cell biology, biomechanics, genomics, surgery, pharmacotherapy, and radiotherapy. The opening sections address epidemiology, cellular and extracellular events, and genetics. Treatment by means of collagenase injection, percutaneous needle fasciotomy, and other surgical and minimally invasive approaches is then extensively discussed. Comparative studies of different approaches are reviewed, and aspects of patient assessment, examined. The prevention and treatment of disease recurrences are also addressed. Further sections consider related conditions, other treatment options, and future pathways for research. This book should be read by all who treat or conduct research into Dupuytren disease. It is based on presentations delivered at the 2015 International Conference on Dupuytren Disease, held in Groningen, the Netherlands, which was designed to promote a coordinated global response to the disease involving patients, scientists, and clinicians.

Dupuytren Disease and Related Diseases - The Cutting Edge

Dupuytren Disease and Related Diseases - The Cutting Edge PDF Author: Paul M. N. Werker
Publisher: Springer
ISBN: 3319321994
Category : Medical
Languages : en
Pages : 450

Get Book

Book Description
In this book, leading international experts showcase the latest advances in research into Dupuytren disease and its clinical management. The coverage spans all relevant specialties, including cell biology, biomechanics, genomics, surgery, pharmacotherapy, and radiotherapy. The opening sections address epidemiology, cellular and extracellular events, and genetics. Treatment by means of collagenase injection, percutaneous needle fasciotomy, and other surgical and minimally invasive approaches is then extensively discussed. Comparative studies of different approaches are reviewed, and aspects of patient assessment, examined. The prevention and treatment of disease recurrences are also addressed. Further sections consider related conditions, other treatment options, and future pathways for research. This book should be read by all who treat or conduct research into Dupuytren disease. It is based on presentations delivered at the 2015 International Conference on Dupuytren Disease, held in Groningen, the Netherlands, which was designed to promote a coordinated global response to the disease involving patients, scientists, and clinicians.

Dupuytren’s Disease and Related Hyperproliferative Disorders

Dupuytren’s Disease and Related Hyperproliferative Disorders PDF Author: Charles Eaton
Publisher: Springer Science & Business Media
ISBN: 3642226965
Category : Medical
Languages : en
Pages : 462

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Book Description
This book is based on results of the 2010 International Symposium on Dupuytren's disease held in Miami, Florida, but it also includes new data and additional chapters. It is hoped that it will raise awareness of this underestimated condition and promote cooperative efforts to work towards a cure. Up to date information is provided on the epidemiology, biology, and pathology of the disease. The principles and specifics of treatment are explored in detail. The indications for and techniques of radiotherapy, minimally invasive treatments and open surgery are fully explained. The role of physical therapy is considered as well as the care of relapse and complications. The treatment of Ledderhose’s disease and Peyronie’s disease is also discussed. This book provides invaluable information for hand surgeons, podiatrists, orthopedists, radiation therapy specialists and general practitioners. It will help to foster an interdisciplinary approach to the understanding and management of this debilitating disorder.

Dupuytren's Disease - E-BOOK

Dupuytren's Disease - E-BOOK PDF Author: Lawrence C. Hurst
Publisher: Elsevier Health Sciences
ISBN: 0443114889
Category : Medical
Languages : en
Pages : 144

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Book Description
Dupuytren's Disease: A Scientific Review offers consolidated, up-to-date coverage of both the basic normal (nonpathologic) science and cutting-edge science of this progressive disorder. Drs. Lawrence C. Hurst, Marie A. Badalamente, and David Edward Komatsu break down the complex topic of Dupuytren’s contracture into its basic scientific components. Hand surgeons, plastic surgeons, and orthopaedic surgeons will find this unique, concise title to be especially helpful in their practices. Includes chapters on prevalence of Dupuytren's disease, normal genetics and the genetic abnormalities associated with Dupuytren's disease, and collagen and collagen synthesis in healthy fascia and Dupuytren's disease. Provides numerous illustrations throughout. Contains an in-depth bibliography and a useful, complete glossary of related terms. Consolidates today's available information on Dupuytren’s science into a single, convenient resource.

Dupuytren's Disease

Dupuytren's Disease PDF Author: Lawrence C. Hurst
Publisher: Elsevier
ISBN: 9780443114878
Category : Medical
Languages : en
Pages : 0

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Book Description
Dupuytren's Disease: A Scientific Review offers consolidated, up-to-date coverage of both the basic normal (nonpathologic) science and cutting-edge science of this progressive disorder. Drs. Lawrence C. Hurst, Marie A. Badalamente, and David Edward Komatsu break down the complex topic of Dupuytren's contracture into its basic scientific components. Hand surgeons, plastic surgeons, and orthopaedic surgeons will find this unique, concise title to be especially helpful in their practices. Includes chapters on prevalence of Dupuytren's disease, normal genetics and the genetic abnormalities associated with Dupuytren's disease, and collagen and collagen synthesis in healthy fascia and Dupuytren's disease. Provides numerous illustrations throughout. Contains an in-depth bibliography and a useful, complete glossary of related terms. Consolidates today's available information on Dupuytren's science into a single, convenient resource.

Collagenase in Dupuytren Disease

Collagenase in Dupuytren Disease PDF Author: Giorgio Pajardi
Publisher: Springer
ISBN: 3319658220
Category : Medical
Languages : en
Pages : 142

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Book Description
This book offers detailed guidance on the use of collagenase, or enzymatic fasciotomy, as a nonsurgical treatment for Dupuytren’s contracture and explains its role in relation to the other forms of treatment, including open fasciectomy, needle aponeurotomy, and lipofilling. Clear guidance is provided on technique, current indications, and off-label usage. With the help of tips and tricks from leading experts, the reader will learn how to personalize the procedure to meet the needs of individual patients. Advice is also provided on all aspects of rehabilitation, which is a key determinant of treatment outcome. Collagenase treatment of Dupuytren’s disease has the benefits of low invasiveness and rapid patient recovery and achieves reasonable recurrence-free periods. It is especially valuable in patients with rapid recurrence following surgery. In documenting and appraising every aspect of its use, this book will be of value for all who treat patients with Dupuytren’s disease, including hand surgeons, orthopedists, plastic surgeons, physiatrists, and physiotherapists.

Dupuytren Disease, An Issue of Hand Clinics E-Book

Dupuytren Disease, An Issue of Hand Clinics E-Book PDF Author: Steven Haase
Publisher: Elsevier Health Sciences
ISBN: 0323613896
Category : Medical
Languages : en
Pages :

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Book Description
This issue of Hand Clinics, guest edited by Dr. Steve Haase, as well as the series’ consulting editor Dr. Kevin Chung, will cover a number of key aspects of Dupuytren Disease. Topics discussed within the issue include, but are not limited to: Risk Factors, Disease Associations, and Dupuytren Diathesis, Pathologic Anatomy in Dupuytren Disease, Needle Aponeurotomy for Dupuytren Disease, Development of Collagenase Treatment for Dupuytren Disease, Collagenase Injection for Dupuytren Disease, Alternative and Adjunctive Treatments for Dupuytren Disease, Comparative Outcomes of Dupuytren Disease Treatment, Complications of Dupuytren Disease Treatment, The Role of Hand Therapy in Dupuytren Disease, Treatment of Recurrent Dupuytren Disease, and Advances in Minimally Invasive Treatment of Dupuytren Disease.

Atlas of Essential Orthopaedic Procedures, Second Edition

Atlas of Essential Orthopaedic Procedures, Second Edition PDF Author: Evan Flatow
Publisher: Lippincott Williams & Wilkins
ISBN: 1975124871
Category : Medical
Languages : en
Pages : 1008

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Book Description
Covering more than 100 fundamental orthopaedic techniques, Atlas of Essential Orthopaedic Procedures, 2nd edition offers a highly illustrated, step-by-step guide to the wide variety of conditions you’re most likely to see in practice. The easy-to-follow format begins with patient selection, walks you through a detailed, step-by-step description of the procedure, and concludes with the author’s surgical pearls—all heavily illustrated with radiographs, intraoperative photographs, and line drawings for optimal visualization of the procedure. This technique-focused reference is an essential resource for busy orthopaedic surgeons and a must-have reference for orthopaedic residency.

Tips and Tricks in Plastic Surgery

Tips and Tricks in Plastic Surgery PDF Author: Seth R. Thaller
Publisher: Springer Nature
ISBN: 3030780287
Category : Medical
Languages : en
Pages : 818

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Book Description
The book covers the most innovative, contemporary, and common plastic surgery procedures, and aims to improve both reconstructive and aesthetic surgical results while decreasing the incidence of complications. In doing so, patient satisfaction, quality of care, and safety are enhanced. The text provides a wealth of knowledge seeking to enhance results, reduce morbidity, and ensure patient satisfaction. The book consists of five parts, running the gamut of Aesthetic Surgery, Reconstructive Procedures, Pediatric and Craniomaxillofacial Surgery, Adjunctive Procedures, and finally Hand and Upper Extremity. Written by experts in the field, each chapter describes tips and tricks through clear technical details, medical illustrations and, in some chapters, detailed videos. Tips and Tricks in Plastic Surgery serves as a valuable resource for clinicians, professionals and practitioners, as well as medical students on rotation.

Radiation and the Immune System: Current Knowledge and Future Perspectives

Radiation and the Immune System: Current Knowledge and Future Perspectives PDF Author: Katalin Lumniczky
Publisher: Frontiers Media SA
ISBN: 2889454746
Category :
Languages : en
Pages : 283

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Book Description
For long, high dose ionizing radiation was considered as a net immune suppressing agent, as shown, among others, by the exquisite radiosensitivity of the lymphoid system to radiation-induced cell killing. However, recent advances in radiobiology and immunology have made this picture more complex. For example, the recognition that radiation-induced bystander effects, share common mediators with various immunological signalling processes, suggests that they are at least partly immune mediated. Another milestone was the finding, in the field of onco-immunology, that local tumor irradiation can modulate the immunogenicity of tumor cells and the anti-tumor immune responsiveness both locally, in the tumor microenvironment, and at systemic level. These observations paved the way for studies exploring optimal combinations of radiotherapy and immunotherapy in order to achieve a synergistic effect to eradicate tumors. However, not all interactions between radiation and the immune system are beneficial, as it was recognized that many of radiation-induced late side effects are also of immune and inflammatory nature. Currently perhaps the most studied field of research in radiation biology is focused around the biological effects of low doses, where many of the observed pathophysiological endpoints are due to mechanisms other than direct radiation-induced cell killing and are immune-related. Finally, it must not be forgotten that the interactions between the ionizing radiations and the immune system are bi-directional, and activation of the immune system also influences the outcome of radiation exposure. This Research Topic brings together 23 articles and aims to give an overview of the complex and very often contradictory nature of the interactions between ionizing radiation and the immune system. Due to its increasing penetrance in the population both through medical diagnostic or environmental sources or during cosmic travel low dose ionizing radiation exposure is becoming a major epidemiological concern world-wide. Several of the articles within the Research Topic specifically address potential long-term health consequences and the underlying mechanisms of low dose radiation exposure. A major intention of the Editors was also to draw the attention of the non-radiobiological scientific community on the fact that ionizing radiation is by far more than purely an immune suppressing agent.

Green's Operative Hand Surgery

Green's Operative Hand Surgery PDF Author: Scott W. Wolfe
Publisher: Elsevier Health Sciences
ISBN: 0323697941
Category : Medical
Languages : en
Pages : 2617

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Book Description
Widely recognized as the gold standard reference in the field, Green's Operative Hand Surgery, 8th Edition, provides complete coverage of the surgical and nonsurgical management of the full range of upper extremity conditions. In a clearly written and well-illustrated format, it contains both foundational content for residents and fellows as well as new approaches, case-based controversies, and outcomes-based solutions for practitioners. Drs. Scott W. Wolfe, William C. Pederson, Scott H. Kozin, and Mark S Cohen, along with new, international contributing authors, provide expert perspectives and preferred methods for all aspects of today’s hand, wrist, and elbow surgery. Contains thoroughly revised and updated indications and techniques to treat the full spectrum of upper extremity disorders. Highlights the latest advances and approaches, such as wide-awake local anesthesia no tourniquet (WALANT) hand surgery, nerve transfer techniques, tendon transfer and tendon avulsion repairs, skin grafting techniques, and more. Offers nearly 140 innovative and high-resolution videos (99 are NEW) that provide real-life, step-by-step guidance on key procedures. Provides state-of-the-art information on wrist arthritis, hand trauma, new arthroplasties, targeted muscle reinnervation, wrist instability surgeries, fracture management, rehabilitation, congenital disorders, orthotic interventions, and more. Includes newly updated, high-resolution illustrations, images, and photos throughout. Presents case-based controversies and unique solutions, plus current views on what works and what does not, based on recent science and outcome measures.