Drug-induced Dementia

Drug-induced Dementia PDF Author: MD Grace E. Jackson
Publisher:
ISBN: 9781438972312
Category : Health & Fitness
Languages : en
Pages : 464

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Book Description
Under the influence of declining birth rates, expanding longevity, and changing population structures around the world, the global prevalence of senile dementia is expected to increase more than four-fold within the next forty years. Within the United States alone, the number of affected individuals over the age of 65 is expected to rise exponentially from 8 million cases (2% of the entire population in the year 2000), to 18 million retirees (roughly 4.5% of the national census in the year 2040). Although they are striking, these statistics quite likely underestimate the scope of the coming epidemic, as they fail to consider the impact of under-diagnosis, early-onset disease, and the potential for a changing incidence of illness in the context of increasingly toxic environments. In the face of this imminent crisis, concerned observers have called for policies and practices which aim to prevent, limit, or reverse dementia. Drug-Induced Dementia: A Perfect Crime is a timely resource which reveals why and how medical treatments themselves - specifically, psychopharmaceuticals - are a substantial cause of brain degeneration and premature death. A first-of-its-kind resource for patients and clinicians, the book integrates research findings from epidemiology (observational studies of patients in the "real world"), basic biology (animal experiments), and clinical science (neuroimaging and autopsy studies) in order to demonstrate the dementing and deadly effects of psychiatric drugs. Highlighted by more than 100 neuroimages, slides of tissue specimens, and illustrations, the book uniquely describes: the societal roots of the problem (target organ toxicity, regulatory incompetence, and performativity) the subtypes and essential causes of dementia the patterns, prevalence, and causes of dementia associated with antidepressants, antipsychotics, anxiolytics, mood stabilizers, and stimulants and the actions and reforms which patients, providers, and policy makers might immediately pursue, in an effort to mitigate the causes and consequences of this iatrogenic tragedy.

Drug-induced Dementia

Drug-induced Dementia PDF Author: MD Grace E. Jackson
Publisher:
ISBN: 9781438972312
Category : Health & Fitness
Languages : en
Pages : 464

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Book Description
Under the influence of declining birth rates, expanding longevity, and changing population structures around the world, the global prevalence of senile dementia is expected to increase more than four-fold within the next forty years. Within the United States alone, the number of affected individuals over the age of 65 is expected to rise exponentially from 8 million cases (2% of the entire population in the year 2000), to 18 million retirees (roughly 4.5% of the national census in the year 2040). Although they are striking, these statistics quite likely underestimate the scope of the coming epidemic, as they fail to consider the impact of under-diagnosis, early-onset disease, and the potential for a changing incidence of illness in the context of increasingly toxic environments. In the face of this imminent crisis, concerned observers have called for policies and practices which aim to prevent, limit, or reverse dementia. Drug-Induced Dementia: A Perfect Crime is a timely resource which reveals why and how medical treatments themselves - specifically, psychopharmaceuticals - are a substantial cause of brain degeneration and premature death. A first-of-its-kind resource for patients and clinicians, the book integrates research findings from epidemiology (observational studies of patients in the "real world"), basic biology (animal experiments), and clinical science (neuroimaging and autopsy studies) in order to demonstrate the dementing and deadly effects of psychiatric drugs. Highlighted by more than 100 neuroimages, slides of tissue specimens, and illustrations, the book uniquely describes: the societal roots of the problem (target organ toxicity, regulatory incompetence, and performativity) the subtypes and essential causes of dementia the patterns, prevalence, and causes of dementia associated with antidepressants, antipsychotics, anxiolytics, mood stabilizers, and stimulants and the actions and reforms which patients, providers, and policy makers might immediately pursue, in an effort to mitigate the causes and consequences of this iatrogenic tragedy.

Drug-Induced Dementia

Drug-Induced Dementia PDF Author: Grace E. Jackson
Publisher: AuthorHouse
ISBN: 1438972326
Category : Family & Relationships
Languages : en
Pages : 468

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Book Description
Under the influence of declining birth rates, expanding longevity, and changing population structures around the world, the global prevalence of senile dementia is expected to increase more than four-fold within the next forty years. Within the United States alone, the number of affected individuals over the age of 65 is expected to rise exponentially from 8 million cases (2% of the entire population in the year 2000), to 18 million retirees (roughly 4.5% of the national census in the year 2040). Although they are striking, these statistics quite likely underestimate the scope of the coming epidemic, as they fail to consider the impact of under-diagnosis, early-onset disease, and the potential for a changing incidence of illness in the context of increasingly toxic environments. In the face of this imminent crisis, concerned observers have called for policies and practices which aim to prevent, limit, or reverse dementia. Drug-Induced Dementia: A Perfect Crime is a timely resource which reveals why and how medical treatments themselves – specifically, psychopharmaceuticals – are a substantial cause of brain degeneration and premature death. A first-of-its-kind resource for patients and clinicians, the book integrates research findings from epidemiology (observational studies of patients in the "real world"), basic biology (animal experiments), and clinical science (neuroimaging and autopsy studies) in order to demonstrate the dementing and deadly effects of psychiatric drugs. Highlighted by more than 100 neuroimages, slides of tissue specimens, and illustrations, the book uniquely describes: Ø the societal roots of the problem(target organ toxicity, regulatory incompetence, and performativity) Ø the subtypes and essential causes of dementia Ø the patterns, prevalence, and causes of dementia associated with antidepressants, antipsychotics, anxiolytics, mood stabilizers, and stimulants and Ø the actions and reforms which patients, providers, and policy makers might immediately pursue, in an effort to mitigate the causes and consequences of this iatrogenic tragedy.

Drug-induced Neurological Disorders

Drug-induced Neurological Disorders PDF Author: Kewal K. Jain
Publisher: Hogrefe Publishing
ISBN: 9780889374256
Category : Drugs
Languages : en
Pages : 0

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Book Description
Now in its third edition, this book remains the only source of comprehensive information about drug-induced neurological disorders. The introduction of new drugs and biological therapies have led to new adverse reactions affecting the nervous system that need to be differentiated from naturally occurring neurological disorders. The book does not simply document adverse reactions but pathomechanisms are described wherever information is available. Methods of management of drug-induced neurological disorders are also described. The primary audience is clinicians involved in the management of neurological and psychiatric disorders. The book is also a useful source of information for neuropharmacologists and pharmaceutical physicians involved in advisory capacities to the biopharmaceutical industry.

Psychiatry of Parkinson's Disease

Psychiatry of Parkinson's Disease PDF Author: K.P. Ebmeier
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805598017
Category : Medical
Languages : en
Pages : 160

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Book Description
Psychiatric symptoms are common in the neurological and geriatric care of patients with Parkinson’s disease. This book assembles short reviews from experts in the field to chart the various psychiatric syndromes known in Parkinson’s disease, their presentation, etiology and management. Presented are special topics on epidemiology of psychiatric symptoms, affective disorders and apathy, early cognitive impairment through to dementia, visuoperceptual dysfunction, psychotic disorders, sleep disturbances, impulse disorders and sexual problems. Further, rarely discussed issues, such as the relationship between somatoform disorders and parkinsonism are reviewed. This publication is essential reading for old age psychiatrists, gerontologists and neurologists who work with patients suffering from Parkinson’s disease. In addition, health practitioners who deal with senior patients, as well as scientists who need a quick update on the progress in this important clinical field will find this volume a helpful reference.

Approaching Death

Approaching Death PDF Author: Committee on Care at the End of Life
Publisher: National Academies Press
ISBN: 0309518253
Category : Medical
Languages : en
Pages : 457

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Book Description
When the end of life makes its inevitable appearance, people should be able to expect reliable, humane, and effective caregiving. Yet too many dying people suffer unnecessarily. While an "overtreated" dying is feared, untreated pain or emotional abandonment are equally frightening. Approaching Death reflects a wide-ranging effort to understand what we know about care at the end of life, what we have yet to learn, and what we know but do not adequately apply. It seeks to build understanding of what constitutes good care for the dying and offers recommendations to decisionmakers that address specific barriers to achieving good care. This volume offers a profile of when, where, and how Americans die. It examines the dimensions of caring at the end of life: Determining diagnosis and prognosis and communicating these to patient and family. Establishing clinical and personal goals. Matching physical, psychological, spiritual, and practical care strategies to the patient's values and circumstances. Approaching Death considers the dying experience in hospitals, nursing homes, and other settings and the role of interdisciplinary teams and managed care. It offers perspectives on quality measurement and improvement, the role of practice guidelines, cost concerns, and legal issues such as assisted suicide. The book proposes how health professionals can become better prepared to care well for those who are dying and to understand that these are not patients for whom "nothing can be done."

Evidence-based Clinical Practice Guideline for Deprescribing Cholinesterase Inhibitors and Memantine

Evidence-based Clinical Practice Guideline for Deprescribing Cholinesterase Inhibitors and Memantine PDF Author: E. Reeve
Publisher:
ISBN: 9780648265818
Category :
Languages : en
Pages :

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Book Description


The American Psychiatric Association Practice Guideline on the Use of Antipsychotics to Treat Agitation or Psychosis in Patients With Dementia

The American Psychiatric Association Practice Guideline on the Use of Antipsychotics to Treat Agitation or Psychosis in Patients With Dementia PDF Author: American Psychiatric Association
Publisher: American Psychiatric Pub
ISBN: 0890426775
Category : Antipsychotic drugs
Languages : en
Pages : 220

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Book Description
The guideline offers clear, concise, and actionable recommendation statements to help clinicians to incorporate recommendations into clinical practice, with the goal of improving quality of care. Each recommendation is given a rating that reflects the level of confidence that potential benefits of an intervention outweigh potential harms.

Clinical Psychopharmacology

Clinical Psychopharmacology PDF Author: Prakash B. Behere
Publisher: Springer
ISBN: 9811320926
Category : Medical
Languages : en
Pages : 180

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Book Description
This book provides practical information on how to use various psychotropic drugs in clinical practice, focusing on their mechanisms of action on receptors and enzymes in the brain. Divided into 11 chapters, it covers all main drug classes, with a dedicated chapter each on special populations and upcoming drugs. All the drugs discussed are presented in the same design format in order to facilitate rapid access to information. Specifically, each drug is individually divided into sections - its history and introduction, classification, pharmacological action, doses, drug interactions, indications, side effects and special populations. Only the essential facts about each drug have been included, so as to make the content concise and to avoid dilution of important information. To aid with review, key points are summarized at the end of each chapter.

Hepatotoxicity

Hepatotoxicity PDF Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781719520
Category : Medical
Languages : en
Pages : 848

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Book Description
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Drug Treatment in Dementia

Drug Treatment in Dementia PDF Author: Roy Jones
Publisher: John Wiley & Sons
ISBN: 0470698195
Category : Medical
Languages : en
Pages : 144

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Book Description
This timely book reviews the current status of drug treatments in dementia, both in practice and in research. It commences with a brief overview of the dementia syndrome and provides guidance in making a diagnosis. It then focuses on treatment of the cognitive function, psychological and behavioural symptoms and co-existing diseases. Chapters devoted to measuring the effects and cost-effectiveness of anti-dementia drugs are included.