Dietary Induction Models of Nutritional Disorders in Rodents PDF Download
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Author: Jailane de Souza Aquino
Publisher: Cambridge Scholars Publishing
ISBN: 1527504875
Category : Medical
Languages : en
Pages : 206
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Book Description
This book addresses one of the most controversial topics in Ethics and Bioethics since the beginning of physiology and comparative anatomy, as viewed from the perspective of experienced researchers in the fields of nutrition, bioethics and translational research. The book provides up-to-date information on dietary induction models of diabetes, obesity, hypertension, dyslipidaemia and malnutrition in experimental animal models, with a focus and direction for future clinical studies in the area of health sciences. It directly describes the importance of pre-clinical studies in the construction of translational research, being useful for academic-scientific institutions, students and health professionals such as nutritionists, doctors, pharmacists, psychologists, and nurses, among others.
Author: Jailane de Souza Aquino
Publisher: Cambridge Scholars Publishing
ISBN: 1527504875
Category : Medical
Languages : en
Pages : 206
Get Book
Book Description
This book addresses one of the most controversial topics in Ethics and Bioethics since the beginning of physiology and comparative anatomy, as viewed from the perspective of experienced researchers in the fields of nutrition, bioethics and translational research. The book provides up-to-date information on dietary induction models of diabetes, obesity, hypertension, dyslipidaemia and malnutrition in experimental animal models, with a focus and direction for future clinical studies in the area of health sciences. It directly describes the importance of pre-clinical studies in the construction of translational research, being useful for academic-scientific institutions, students and health professionals such as nutritionists, doctors, pharmacists, psychologists, and nurses, among others.
Author: Jailane de Souza
Publisher:
ISBN: 9781527504868
Category :
Languages : en
Pages : 0
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Book Description
This book addresses one of the most controversial topics in Ethics and Bioethics since the beginning of physiology and comparative anatomy, as viewed from the perspective of experienced researchers in the fields of nutrition, bioethics and translational research. The book provides up-to-date information on dietary induction models of diabetes, obesity, hypertension, dyslipidaemia and malnutrition in experimental animal models, with a focus and direction for future clinical studies in the area of health sciences. It directly describes the importance of pre-clinical studies in the construction of translational research, being useful for academic-scientific institutions, students and health professionals such as nutritionists, doctors, pharmacists, psychologists, and nurses, among others.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309051266
Category : Science
Languages : en
Pages : 188
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Book Description
In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.
Author: Patrick C. Even
Publisher: Frontiers Media SA
ISBN: 2889454258
Category :
Languages : en
Pages : 161
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Book Description
Not only developed countries, but also most developing areas of the world, have experienced a surge in obesity prevalence over recent decades. Obesity complications are now among the leading causes of premature mortality, encompassing conditions such as coronary heart disease, stroke, and type 2 diabetes. This places a heavy burden on contemporary healthcare systems. While rodent models have limitations as experimental models of human obesity-related disease, study of rats and mice either spontaneously prone - or resistant - to obesity, or genetically engineered to illuminate underlying mechanisms has yielded key information about the metabolic defects linked to obesity, and their associated diseases. This topic includes both original research studies and reviews of the use of animal studies in specific areas of obesity-related disease. Various methodological approaches are discussed, with evaluation of the extent to which use of animal models has facilitated progress, or, conversely, has proved a cul de sac in investigation of human disease mechanisms. Consideration is also given to future strategies to use such rodent models optimally to enhance comprehension and treatment of pandemic human obesity-related diseases.
Author: Cynthia Petrie Smith
Publisher:
ISBN:
Category : Animal models in research
Languages : en
Pages : 62
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Book Description
Author:
Publisher:
ISBN:
Category : Agriculture
Languages : en
Pages : 1120
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Book Description
Author: Alice Sabatino
Publisher: Frontiers Media SA
ISBN: 2889740056
Category : Medical
Languages : en
Pages : 120
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Book Description
Author:
Publisher:
ISBN:
Category : Agriculture
Languages : en
Pages : 722
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Book Description
Author: Randy L. Jirtle
Publisher: Springer Science & Business Media
ISBN: 3642368271
Category : Medical
Languages : en
Pages : 361
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Book Description
There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without a change in the sequence of the DNA. The main components of the epigenetic code are DNA methylation, histone modifications, and non-coding RNAs. The epigenetic programs are established as stem cell differentiate during embryogenesis, and they are normally faithfully reproduced during mitosis. Moreover, they can also be maintained during meiosis, resulting in epigenetic transgenerational disease inheritance, and also potentially introducing phenotypic variation that is selected for in the evolution of new species. The objective of this two volume book is to provide evidence that environmental exposures during early development can alter the risk of developing medical conditions, such as asthma, autism, cancer, cardiovascular disease, diabetes, obesity, and schizophrenia later in life by modifying the epigenome. Consequently, epigenetic research promises to markedly improve our ability to diagnosis, prevent, and treat the pathological conditions of humans; however, it also introduces unique legal and ethical issues. This volume highlights the correlation between environmental factors and complex diseases, such as autism, addiction, neurological diseases, diabetes, obesity and cancer. It concludes with a chapter on legal and ethical implications of epigenetics.
Author: Paramjit S. Tappia
Publisher: Springer Nature
ISBN: 3030353583
Category : Medical
Languages : en
Pages : 348
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Book Description
According to the World Health Organization, the epidemic of global obesity has nearly tripled since 1975. In 2016, more than 1.9 billion adults were overweight, over 650 million of which were obese. Being overweight and obese has been linked to a number of non-communicable, chronic diseases. Pathophysiology of Obesity-Induced Health Complications is a compilation of review articles dedicated to describe co-morbidities associated with obesity. The wide range that is covered is of significant interest to basic research scientists, clinicians and graduate students who are engaged in studying obesity-induced health complications. Furthermore, this book highlights the potential of novel approaches for the prevention and treatment of obesity and its related illnesses. Nineteen articles in this book are organized in four sections that are designed to provide an overview of obesity-induced health complications. The first section serves as an introductory section on the prevalence, causes, consequences, treatments and preventive approaches for obesity. Section two covers the metabolic disturbances and inflammation due to obesity. The third section is focused on neurological and visceral complications as a consequence of obesity. The final section covers strategies for the prevention of obesity-induced complications. The book illustrates that obesity can result in a diverse range of pathophysiological conditions that adversely affect health.
