Defense against Bioterror: Detection Technologies, Implementation Strategies and Commercial Opportunities

Defense against Bioterror: Detection Technologies, Implementation Strategies and Commercial Opportunities PDF Author: Dennis Morrison
Publisher: Springer Science & Business Media
ISBN: 1402033842
Category : Science
Languages : en
Pages : 321

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Book Description
This is a critical assessment of breakthrough biosensor technologies that will allow for the rapid identification of biological threat agents in the environment and human population. The book provides a comprehensive overview of the current state of biological weapons threat, and reviews biosensor technologies including detection platforms, networked alarm-type biodetector systems, implementation strategies, electro-optical and electrochemical biosensors.

Defense against Bioterror: Detection Technologies, Implementation Strategies and Commercial Opportunities

Defense against Bioterror: Detection Technologies, Implementation Strategies and Commercial Opportunities PDF Author: Dennis Morrison
Publisher: Springer Science & Business Media
ISBN: 1402033842
Category : Science
Languages : en
Pages : 321

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Book Description
This is a critical assessment of breakthrough biosensor technologies that will allow for the rapid identification of biological threat agents in the environment and human population. The book provides a comprehensive overview of the current state of biological weapons threat, and reviews biosensor technologies including detection platforms, networked alarm-type biodetector systems, implementation strategies, electro-optical and electrochemical biosensors.

Commercial and Pre-commercial Cell Detection Technologies for Defence Against Bioterror

Commercial and Pre-commercial Cell Detection Technologies for Defence Against Bioterror PDF Author: Laura M. Lechuga
Publisher: IOS Press
ISBN: 1586038583
Category : Medical
Languages : en
Pages : 180

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Book Description
As a response to the rapidly emerging threat of bioterrorism, this volume aims to exchange information on commercially available technologies and equipment for defense against bioterrorism; to further the development of new biosensor system prototypes into a commercially available apparatus and to explore human factors in BWA biosensors.

Countering Bioterrorism

Countering Bioterrorism PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309086078
Category : Political Science
Languages : en
Pages : 105

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Book Description
The attacks of September 11 and the release of anthrax spores revealed enormous vulnerabilities in the U.S. public-health infrastructure and suggested similar vulnerabilities in the agricultural infrastructure as well. The traditional public health response-surveillance (intelligence), prevention, detection, response, recovery, and attribution-is the paradigm for the national response not only to all forms of terrorism but also to emerging infectious diseases. Thus, investments in research on bioterrorism will have enormous potential for application in the detection, prevention, and treatment of emerging infectious diseases that also are unpredictable and against which we must be prepared. The deciphering of the human genome sequence and the complete elucidation of numerous pathogen genomes, our rapidly increasing understanding of the molecular mechanisms of pathogenesis and of immune responses, and new strategies for designing drugs and vaccines all offer unprecedented opportunities to use science to counter bioterrorist threats. But these same developments also allow science to be misused to create new agents of mass destruction. Hence the effort to confront bioterrorism must be a global one. Countering Bioterrorism makes the following recommendations: Recommendation 1: All agencies with responsibility for homeland security should work together to establish stronger and more meaningful working ties between the intelligence, S&T, and public health communities. Recommendation 2: Federal agencies should work cooperatively and in collaboration with industry to develop and evaluate rapid, sensitive, and specific early-detection technologies. Recommendation 3: Create a global network for detection and surveillance, making use of computerized methods for real-time reporting and analysis to rapidly detect new patterns of disease locally, nationally, and ultimately- internationally. The use of high-throughput methodologies that are being increasingly utilized in modern biological research should be an important component of this expanded and highly automated surveillance strategy. Recommendation 4: Use knowledge of complex biological patterns and high-throughput laboratory automation to classify and diagnose infections in patients in primary care settings. Recommendation 5: USDA should create an agency for control and prevention of plant disease. This agency should have the capabilities necessary to deal effectively with biothreats.

Commercial and Pre-Commercial Cell Detection Technologies for Defence Against Bioterror

Commercial and Pre-Commercial Cell Detection Technologies for Defence Against Bioterror PDF Author: L.M. Lechuga
Publisher: IOS Press
ISBN: 160750328X
Category : Political Science
Languages : en
Pages : 180

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Book Description
As a response to the rapidly emerging threat of bioterrorism, the objectives of this volume on Commercial and Pre-Commercial Cell Detection Technologies for Defence against Bioterror are to exchange information on commercially available technologies and equipment for defense against bioterrorism; to further the development of new biosensor system prototypes into a commercially available apparatus and to explore human factors in BWA biosensors. The new commercial and pre-commercial technologies that are currently emerging in the world are presented and explained. Furthermore, there is a discussion about the interaction of modern detection systems with society and a trial for improvement of the relation between the scientific community and commercial entities. There are four major areas highlighted: the first is a presentation of the most advanced biosensors and biodetection system which can be found in the market or are quite close to commercialization. Systems as the BIOHAWKTM, SASS 2000, RAPTOR, Bionas® 2500, OWLS, or a portable SPR are presented in this section. The second issue is a presentation of the advances in the research of biodetection devices as DNA and protein microchips, micro and nanophotonic sensors, CMOS microsensor chips, electrochemical arrays, physical platforms, electro optical detection, mass detection, etc. Then, there is a description of the latest developments in the employment of bioreceptor layers for the selective detection of BWA, as protein signatures, molecular imprinted polymers, membrane engineering (MIME), cell signatures, monoclonal antibodies, synthetic antibodies and lytic phages, among others. The last part is the discussion of the human factor: societal issues related to sensor development and employment for BWA detection.

Commercial and Pre-commercial Cell Detection Technologies for Defence Against Bioterror

Commercial and Pre-commercial Cell Detection Technologies for Defence Against Bioterror PDF Author: Laura M. Lechuga
Publisher: IOS Press
ISBN: 9781435678019
Category : Political Science
Languages : en
Pages : 167

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Book Description


Biodefense in the Age of Synthetic Biology

Biodefense in the Age of Synthetic Biology PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309465184
Category : Technology & Engineering
Languages : en
Pages : 189

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Book Description
Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.

Explosives Detection

Explosives Detection PDF Author: Lorenzo Capineri
Publisher: Springer Nature
ISBN: 940241729X
Category : Technology & Engineering
Languages : en
Pages : 343

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Book Description
This volume presents selected contributions from the “Advanced Research Workshop on Explosives Detection” hosted by the Department of Information Engineering of the University of Florence, Italy in 2018. The main goal of the workshop was to find out how Science for Peace and Security projects in the field of Explosives Detection contribute to the development and/or refinement of scientific and technical knowledge and competencies. The findings of the workshop, presented in the last section of the book, determine future actions and direction of the SPS Programme in the field of explosives detection and management.The NATO Science for Peace and Security (SPS) Programme, promotes dialogue and practical cooperation between NATO member states and partner nations based on scientific research, technological innovation and knowledge exchange. Several initiatives were launched in the field of explosive detection and clearance, as part of NATO’s enhanced role in the international fight against terrorism. Experts and scientists from NATO members and partner countries have been brought together in multi-year projects, within the framework of the SPS Programme, to cooperate in the scientific research in explosive detection field, developing new technologies and methods to be implemented in order to detect explosive substances in different contexts.

The Biological Threat Reduction Program of the Department of Defense

The Biological Threat Reduction Program of the Department of Defense PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309179513
Category : Political Science
Languages : en
Pages : 120

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Book Description
This Congressionally-mandated report identifies areas for further cooperation with Russia and other states of the former Soviet Union under the Cooperative Threat Reduction (CTR) program of the Department of Defense in the specific area of prevention of proliferation of biological weapons. The report reviews relevant U.S. government programs, and particularly the CTR program, and identifies approaches for overcoming obstacles to cooperation and for increasing the long-term impact of the program. It recommends strong support for continuation of the CTR program.

BioWatch and Public Health Surveillance

BioWatch and Public Health Surveillance PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 030918763X
Category : Political Science
Languages : en
Pages : 252

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Book Description
Following the attacks of September 11, 2001 and the anthrax letters, the ability to detect biological threats as quickly as possible became a top priority. In 2003 the Department of Homeland Security (DHS) introduced the BioWatch program-a federal monitoring system intended to speed detection of specific biological agents that could be released in aerosolized form during a biological attack. The present volume evaluates the costs and merits of both the current BioWatch program and the plans for a new generation of BioWatch devices. BioWatch and Public Health Surveillance also examines infectious disease surveillance through hospitals and public health agencies in the United States, and considers whether BioWatch and traditional infectious disease surveillance are redundant or complementary.

Biological Threats and Terrorism

Biological Threats and Terrorism PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030916995X
Category : Political Science
Languages : en
Pages : 335

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Book Description
In the wake of September 11th and recent anthrax events, our nation's bioterrorism response capability has become an imminent priority for policymakers, researchers, public health officials, academia, and the private sector. In a three-day workshop, convened by the Institute of Medicine's Forum on Emerging Infections, experts from each of these communities came together to identify, clarify, and prioritize the next steps that need to be taken in order to prepare and strengthen bioterrorism response capabilities. From the discussions, it became clear that of utmost urgency is the need to cast the issue of a response in an appropriate framework in order to attract the attention of Congress and the public in order to garner sufficient and sustainable support for such initiatives. No matter how the issue is cast, numerous workshop participants agreed that there are many gaps in the public health infrastructure and countermeasure capabilities that must be prioritized and addressed in order to assure a rapid and effective response to another bioterrorist attack.