Critical Appraisal of Epidemiological Studies and Clinical Trials

Critical Appraisal of Epidemiological Studies and Clinical Trials PDF Author: Mark Elwood
Publisher: Oxford University Press
ISBN: 0199682895
Category : Medical
Languages : en
Pages : 499

Get Book

Book Description
Critical appraisal is now accepted as central to the development of rational health care and evidence-based medicine, by applying it to questions of aetiology, clinical therapy, and health care management. The reader will learn how to assess the strengths and weaknesses of new studies, and how to conduct their own studies.

Critical Appraisal of Epidemiological Studies and Clinical Trials

Critical Appraisal of Epidemiological Studies and Clinical Trials PDF Author: Mark Elwood
Publisher: Oxford University Press
ISBN: 0199682895
Category : Medical
Languages : en
Pages : 499

Get Book

Book Description
Critical appraisal is now accepted as central to the development of rational health care and evidence-based medicine, by applying it to questions of aetiology, clinical therapy, and health care management. The reader will learn how to assess the strengths and weaknesses of new studies, and how to conduct their own studies.

Critical Appraisal of Epidemiological Studies and Clinical Trials

Critical Appraisal of Epidemiological Studies and Clinical Trials PDF Author: Mark Elwood
Publisher: OUP Oxford
ISBN: 0191004944
Category : Medical
Languages : en
Pages : 615

Get Book

Book Description
This book presents a logical system of critical appraisal, to allow readers to evaluate studies and to carry out their own studies more effectively. This system emphasizes the central importance of cause and effect relationships. Its great strength is that it is applicable to a wide range of issues, and both to intervention trials and observational studies. This system unifies the often different approaches used in epidemiology, health services research, clinical trials, and evidence-based medicine, starting from a logical consideration of cause and effect. The author's approach to the issues of study design, selection of subjects, bias, confounding, and the place of statistical methods has been praised for its clarity and interest. Systematic reviews, meta-analysis, and the applications of this logic to evidence-based medicine, knowledge-based health care, and health practice and policy are discussed. Current and often controversial examples are used, including screening for prostate cancer, publication bias in psychiatry, public health issues in developing countries, and conflicts between observational studies and randomized trials. Statistical issues are explained clearly without complex mathematics, and the most useful methods are summarized in the appendix. The final chapters give six applications of the critical appraisal of major studies: randomized trials of medical treatment and prevention, a prospective and a retrospective cohort study, a small matched case-control study, and a large case-control study. In these chapters, sections of the original papers are reproduced and the original studies placed in context by a summary of current developments.

Critical Appraisal of Epidemiological Studies and Clinical Trials

Critical Appraisal of Epidemiological Studies and Clinical Trials PDF Author: J. Mark Elwood
Publisher: Oxford University Press
ISBN: 0199218250
Category : Causation
Languages : en
Pages : 585

Get Book

Book Description
This book presents a logical system of critical appraisal, to allow readers to evaluate studies and to carry out their own studies more effectively. This system emphasizes the central importance of cause and effect relationships. Its great strength is that it is applicable to a wide range of issues, and both to intervention trials and observational studies. This system unifies the often different approaches used in epidemiology, health services research, clinical trials, and evidence-based medicine, starting from a logical consideration of cause and effect. The author's approach to the issues of study design, selection of subjects, bias, confounding, and the place of statistical methods has been praised for its clarity and interest. Systematic reviews, meta-analysis, and the applications of this logic to evidence-based medicine, knowledge-based health care, and health practice and policy are discussed. Current and often controversial examples are used, including screening for prostate cancer, publication bias in psychiatry, public health issues in developing countries, and conflicts between observational studies and randomized trials. Statistical issues are explained clearly without complex mathematics, and the most useful methods are summarized in the appendix.

Critical Appraisal of Epidemiological Studies and Clinical Trials

Critical Appraisal of Epidemiological Studies and Clinical Trials PDF Author: Mark Elwood
Publisher: OUP Oxford
ISBN: 9780198529552
Category : Medical
Languages : en
Pages : 584

Get Book

Book Description
Critical appraisal is now accepted as central to the development of rational health care and evidence-based medicine, by applying it to questions of aetiology, clinical therapy, and health care management. The reader will learn how to assess the strengths and weaknesses of new studies, and how to conduct their own studies.

Concepts of Epidemiology

Concepts of Epidemiology PDF Author: Raj S. Bhopal
Publisher: Oxford University Press
ISBN: 0198739680
Category : Medical
Languages : en
Pages : 481

Get Book

Book Description
First edition published in 2002. Second edition published in 2008.

Practical Psychiatric Epidemiology

Practical Psychiatric Epidemiology PDF Author: Jayati Das-Munshi
Publisher: Oxford University Press
ISBN: 0191054461
Category : Medical
Languages : en
Pages : 465

Get Book

Book Description
Epidemiology has been defined as the study of the distribution and determinants of health states or events in defined populations and its application to the control of health problems. Psychiatric epidemiology has continued to develop and apply these core principles in relation to mental health and mental disorders. This long-awaited second edition of Practical Psychiatric Epidemiology covers all of the considerable new developments in psychiatric epidemiology that have occurred since the first edition was published. It includes new content on key topics such as life course epidemiology, gene/environment interactions, bioethics, patient and public involvement in research, mixed methods research, new statistical methods, case registers, policy, and implementation. Looking to the future of this rapidly evolving scientific discipline and how it will to respond to the emerging opportunities and challenges posed by 'big data', new technologies, open science and globalisation, this new edition will continue to serve as an invaluable reference for clinicians in practice and in training. It will also be of interest to researchers in mental health and people studying or teaching psychiatric epidemiology at undergraduate or postgraduate level.

Finding What Works in Health Care

Finding What Works in Health Care PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309164257
Category : Medical
Languages : en
Pages : 267

Get Book

Book Description
Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.

Epidemiology for the Advanced Practice Nurse

Epidemiology for the Advanced Practice Nurse PDF Author: Demetrius Porche, DNS, PhD, ANEF, FACHE, FAANP, FAAN
Publisher: Springer Publishing Company
ISBN: 0826185142
Category : Medical
Languages : en
Pages : 465

Get Book

Book Description
Written by nurses for nurses, this graduate-level text disseminates the core principles of epidemiology within a population health framework and provides practical knowledge nurses can use to analyze and improve healthcare in the community. Informed by the evolution of epidemiological science resulting from the Covid-19 pandemic, this book demonstrates how epidemiology can have a profound impact on health. It showcases a variety of settings and epidemiological roles demonstrating the importance and practicality of this discipline. Clear and concise, this text explains the basics of population health followed by epidemiology concepts and designs. It is distinguished by its application-based case studies, analytical tools of epidemiology, and calculations, which foster skill development and necessary familiarity of the subject. Also included is an important Biostatistics Primer, relevant content from Healthy People 2030, and an "Epidemiology in Practice" section focusing on examples from different epidemiology arenas. Key Features: Includes application-based cases, tools, and calculations throughout to help students develop practical epidemiologic skills Provides background and understanding of health disparities and determinants of health Includes relevant information from Healthy People 2030 Includes discussion questions, learning objectives, terminology review, tables, and figures in each chapter Delivers up-to-date information on epidemiology in the time of Covid-19 Includes access to an Instructor's Manual with additional case studies

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide PDF Author: Agency for Health Care Research and Quality (U.S.)
Publisher: Government Printing Office
ISBN: 1587634236
Category : Medical
Languages : en
Pages : 204

Get Book

Book Description
This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

Making Sense of Critical Appraisal

Making Sense of Critical Appraisal PDF Author: Olajide Ajetunmobi
Publisher: CRC Press
ISBN: 1000423468
Category : Medical
Languages : en
Pages : 168

Get Book

Book Description
This handy pocket companion provides all the necessary guidance on how to understand medical research publications, read them critically and decide whether the content of those papers is clinically useful in the care of patients. Illustrated throughout with medically relevant examples, the accessible text encompasses all relevant aspects of study design and clinical audit to give a clear framework to support critical reading for the novice and more experienced reader.