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Author: Xiaobo Zhou
Publisher: World Scientific
ISBN: 9812707042
Category : Science
Languages : en
Pages : 398
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Book Description
Computational systems biology is a new and rapidly developing field of research, concerned with understanding the structure and processes of biological systems at the molecular, cellular, tissue, and organ levels through computational modeling as well as novel information theoretic data and image analysis methods. By focusing on either information processing of biological data or on modeling physical and chemical processes of biosystems, and in combination with the recent breakthrough in deciphering the human genome, computational systems biology is guaranteed to play a central role in disease prediction and preventive medicine, gene technology and pharmaceuticals, and other biotechnology fields. This book begins by introducing the basic mathematical, statistical, and data mining principles of computational systems biology, and then presents bioinformatics technology in microarray and sequence analysis step-by-step. Offering an insightful look into the effectiveness of the systems approach in computational biology, it focuses on recurrent themes in bioinformatics, biomedical applications, and future directions for research.
Author: Xiaobo Zhou
Publisher: World Scientific
ISBN: 9812707042
Category : Science
Languages : en
Pages : 398
Get Book
Book Description
Computational systems biology is a new and rapidly developing field of research, concerned with understanding the structure and processes of biological systems at the molecular, cellular, tissue, and organ levels through computational modeling as well as novel information theoretic data and image analysis methods. By focusing on either information processing of biological data or on modeling physical and chemical processes of biosystems, and in combination with the recent breakthrough in deciphering the human genome, computational systems biology is guaranteed to play a central role in disease prediction and preventive medicine, gene technology and pharmaceuticals, and other biotechnology fields. This book begins by introducing the basic mathematical, statistical, and data mining principles of computational systems biology, and then presents bioinformatics technology in microarray and sequence analysis step-by-step. Offering an insightful look into the effectiveness of the systems approach in computational biology, it focuses on recurrent themes in bioinformatics, biomedical applications, and future directions for research.
Author: Wong Stephen Tin Chi
Publisher: World Scientific Publishing Company
ISBN: 9813106999
Category : Science
Languages : en
Pages : 400
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Book Description
Computational systems biology is a new and rapidly developing field of research, concerned with understanding the structure and processes of biological systems at the molecular, cellular, tissue, and organ levels through computational modeling as well as novel information theoretic data and image analysis methods. By focusing on either information processing of biological data or on modeling physical and chemical processes of biosystems, and in combination with the recent breakthrough in deciphering the human genome, computational systems biology is guaranteed to play a central role in disease prediction and preventive medicine, gene technology and pharmaceuticals, and other biotechnology fields.This book begins by introducing the basic mathematical, statistical, and data mining principles of computational systems biology, and then presents bioinformatics technology in microarray and sequence analysis step-by-step. Offering an insightful look into the effectiveness of the systems approach in computational biology, it focuses on recurrent themes in bioinformatics, biomedical applications, and future directions for research.
Author: Peter Markstein
Publisher: World Scientific
ISBN: 1860948731
Category : Computers
Languages : en
Pages : 472
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Book Description
This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. Abstracts from the keynote addresses and invited talks are also included. The papers not only cover theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field. Sample Chapter(s). Chapter 1: Whole-Genome Analysis of Dorsal Gradient Thresholds in the Drosophila Embryo (102 KB). Contents: Learning Predictive Models of Gene Regulation (C Leslie); Algorithms for Selecting Breakpoint Locations to Optimize Diversity in Protein Engineering by Site-Directed Protein Recombination (W Zheng et al.); Cancer Molecular Pattern Discovery by Subspace Consensus Kernel Classification (X Han); Transcriptional Profiling of Definitive Endoderm Derived from Human Embryonic Stem Cells (H Liu et al.); A Markov Model Based Analysis of Stochastic Biochemical Systems (P Ghosh et al.); Clustering of Main Orthologs for Multiple Genomes (Z Fu & T Jiang); Extraction, Quantification and Visualization of Protein Pockets (X Zhang & C Bajaj); Consensus Contact Prediction by Linear Programming (X Gao et al.); An Active Visual Search Interface for Medline (W Xuan et al.); Exact and Heuristic Algorithms for Weighted Cluster Editing (S Rahmann et al.); Reconcilation with Non-binary Species Trees (B Vernot et al.); and other papers. Readership: Research and application community in bioinformatics, systems biology, medicine, pharmacology and biotechnology. Graduate researchers in bioinformatics and computational biology.
Author: Peter Markstein
Publisher: World Scientific
ISBN: 190897947X
Category : Computers
Languages : en
Pages : 416
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Book Description
This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. There are also abstracts from the keynote addresses and invited talks. The papers cover not only theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field. Contents:Exploring the Ocean's Microbes: Sequencing the Seven Seas (M E Frazier et al.)Protein Network Comparative Genomics (T Ideker)Bioinformatics at Microsoft Research (S Mercer)Protein Fold Recognition Using Gradient Boost Algorithm (F Jiao et al.)Efficient Annotation of Non-Coding RNA Structures Including Pseudoknots via Automated Filters (C Liu et al.)Efficient Generalized Matrix Approximations for Biomarker Discovery and Visualization in Gene Expression Data (W Li et al.)Sorting Genomes by Translocations and Deletions (X Qi et al.)Detection of Cleavage Sites for HIV-1 Protease in Native Proteins (L You)Identifying Biological Pathways via Phase Decomposition and Profile Extraction (Y Zhang & Z Deng)Complexity and Scoring Function of MS/MS Peptide De Novo Sequencing (C Xu & B Ma)Simulating In Vitro Epithelial Morphogenesis in Multiple Environments (M R Grant et al.)and other papers Readership: Research and application community in bioinformatics, systems biology, medicine, pharmacology and biotechnology. A useful reference for graduate researchers in bioinformatics and computational biology. Keywords:Bioinformatics;Computational Biology;Genomics;Proteomics;Structural Biology;Biological Pathways;Phylogenetics;Systems BiologyKey Features:The CSB meetings accepts only the highest quality research paper, with a paper-acceptance rate of below 20%The CSB meeting represents an unique bioinformatics conference in which papers blend bioinformatic tool development with in silico biologyCSB meetings have become one of the most well attended bioinformatics conferencesCSB proceedings are indexed by Medline
Author: Lecca, Paola
Publisher: IGI Global
ISBN: 1613504365
Category : Medical
Languages : en
Pages : 471
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Book Description
The convergence of biology and computer science was initially motivated by the need to organize and process a growing number of biological observations resulting from rapid advances in experimental techniques. Today, however, close collaboration between biologists, biochemists, medical researchers, and computer scientists has also generated remarkable benefits for the field of computer science. Systemic Approaches in Bioinformatics and Computational Systems Biology: Recent Advances presents new techniques that have resulted from the application of computer science methods to the organization and interpretation of biological data. The book covers three subject areas: bioinformatics, computational biology, and computational systems biology. It focuses on recent, systemic approaches in computer science and mathematics that have been used to model, simulate, and more generally, experiment with biological phenomena at any scale.
Author: Peter Markstein
Publisher: World Scientific
ISBN: 1848162634
Category : Science
Languages : en
Pages : 355
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Book Description
This proceedings volume contains 29 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. The papers not only cover theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field.
Author: Kayvan Najarian
Publisher: CRC Press
ISBN: 1439882940
Category : Medical
Languages : en
Pages : 190
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Book Description
The availability of molecular imaging and measurement systems enables today's biologists to swiftly monitor thousands of genes involved in a host of diseases, a critical factor in specialized drug development. Systems Biology and Bioinformatics: A Computational Approach provides students with a comprehensive collection of the computational methods
Author: Andres Kriete
Publisher: Academic Press
ISBN: 0124059384
Category : Computers
Languages : en
Pages : 548
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Book Description
This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. Logical information flow aids understanding of basic building blocks of life through disease phenotypes Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.
Author: Peter Markstein
Publisher: World Scientific
ISBN: 1908978708
Category : Mathematics
Languages : en
Pages : 356
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Book Description
This proceedings volume contains 29 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. The papers not only cover theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field. Contents: Voting Algorithms for the Motif Finding Problem (X-W Liu et al.)MSDash: Mass Spectrometry Database and Search (Z Wu et al.)GaborLocal: Peak Detection in Mass Spectrum by Gabor Filters and Gaussian Local Maxima (N Nguyen et al.)Designing Secondary Structure Profiles for Fast ncRNA Identification (Y Sun & J Buhler)Iterative Non-sequential Protein Structural Alignment (S Salem & M J Zaki)Consistent Alignment of Metabolic Pathways Without Abstraction (F Ay et al.)On the Accurate Construction of Consensus Genetic Maps (Y-H Wu et al.)Graph Wavelet Alignment Kernels for Drug Virtual Screening (A Smalter et al.)and other papers Readership: Graduate students, postdoctoral fellows, researchers, and practitioners in the field of bioinformatics and systems biology; biotech and pharmaceutical companies; computational scientists and engineers interested in biology. Keywords:Bioinformatics;Computational Systems Biology;Computational Techniques;Systems Biology ProblemsKey Features:The CSB meetings accept only the highest-quality research papers, with a paper-acceptance rate of below 20%The CSB meetings represent a unique bioinformatics conference in which papers blend bioinformatic tool development with in silico biologyCSB meetings have become one of the most well-attended bioinformatics conferencesCSB proceedings are indexed by Medline
Author:
Publisher: Elsevier
ISBN: 0128114320
Category : Medical
Languages : en
Pages : 3421
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Book Description
Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases
