Principles of Computational Modelling in Neuroscience

Principles of Computational Modelling in Neuroscience PDF Author: David Sterratt
Publisher: Cambridge University Press
ISBN: 1108483143
Category : Science
Languages : en
Pages : 553

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Book Description
Learn to use computational modelling techniques to understand the nervous system at all levels, from ion channels to networks.

Principles of Computational Modelling in Neuroscience

Principles of Computational Modelling in Neuroscience PDF Author: David Sterratt
Publisher: Cambridge University Press
ISBN: 1108483143
Category : Science
Languages : en
Pages : 553

Get Book

Book Description
Learn to use computational modelling techniques to understand the nervous system at all levels, from ion channels to networks.

Computational Models of Brain and Behavior

Computational Models of Brain and Behavior PDF Author: Ahmed A. Moustafa
Publisher: John Wiley & Sons
ISBN: 1119159067
Category : Psychology
Languages : en
Pages : 586

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Book Description
A comprehensive Introduction to the world of brain and behavior computational models This book provides a broad collection of articles covering different aspects of computational modeling efforts in psychology and neuroscience. Specifically, it discusses models that span different brain regions (hippocampus, amygdala, basal ganglia, visual cortex), different species (humans, rats, fruit flies), and different modeling methods (neural network, Bayesian, reinforcement learning, data fitting, and Hodgkin-Huxley models, among others). Computational Models of Brain and Behavior is divided into four sections: (a) Models of brain disorders; (b) Neural models of behavioral processes; (c) Models of neural processes, brain regions and neurotransmitters, and (d) Neural modeling approaches. It provides in-depth coverage of models of psychiatric disorders, including depression, posttraumatic stress disorder (PTSD), schizophrenia, and dyslexia; models of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, and epilepsy; early sensory and perceptual processes; models of olfaction; higher/systems level models and low-level models; Pavlovian and instrumental conditioning; linking information theory to neurobiology; and more. Covers computational approximations to intellectual disability in down syndrome Discusses computational models of pharmacological and immunological treatment in Alzheimer's disease Examines neural circuit models of serotonergic system (from microcircuits to cognition) Educates on information theory, memory, prediction, and timing in associative learning Computational Models of Brain and Behavior is written for advanced undergraduate, Master's and PhD-level students—as well as researchers involved in computational neuroscience modeling research.

Computational Neuroscience Models of the Basal Ganglia

Computational Neuroscience Models of the Basal Ganglia PDF Author: V. Srinivasa Chakravarthy
Publisher: Springer
ISBN: 9811084947
Category : Technology & Engineering
Languages : en
Pages : 296

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Book Description
The book is a compendium of the aforementioned subclass of models of Basal Ganglia, which presents some the key existent theories of Basal Ganglia function. The book presents computational models of basal ganglia-related disorders, including Parkinson’s disease, schizophrenia, and addiction. Importantly, it highlights the applications of understanding the role of the basal ganglia to treat neurological and psychiatric disorders. The purpose of the present book is to amend and expand on James Houk’s book (MIT press; ASIN: B010BF4U9K) by providing a comprehensive overview on computational models of the basal ganglia. This book caters to researchers and academics from the area of computational cognitive neuroscience.

The Computational Brain, 25th Anniversary Edition

The Computational Brain, 25th Anniversary Edition PDF Author: Patricia S. Churchland
Publisher: MIT Press
ISBN: 0262533391
Category : Science
Languages : en
Pages : 569

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Book Description
An anniversary edition of the classic work that influenced a generation of neuroscientists and cognitive neuroscientists. Before The Computational Brain was published in 1992, conceptual frameworks for brain function were based on the behavior of single neurons, applied globally. In The Computational Brain, Patricia Churchland and Terrence Sejnowski developed a different conceptual framework, based on large populations of neurons. They did this by showing that patterns of activities among the units in trained artificial neural network models had properties that resembled those recorded from populations of neurons recorded one at a time. It is one of the first books to bring together computational concepts and behavioral data within a neurobiological framework. Aimed at a broad audience of neuroscientists, computer scientists, cognitive scientists, and philosophers, The Computational Brain is written for both expert and novice. This anniversary edition offers a new preface by the authors that puts the book in the context of current research. This approach influenced a generation of researchers. Even today, when neuroscientists can routinely record from hundreds of neurons using optics rather than electricity, and the 2013 White House BRAIN initiative heralded a new era in innovative neurotechnologies, the main message of The Computational Brain is still relevant.

Brain and Human Body Modeling

Brain and Human Body Modeling PDF Author: Sergey Makarov
Publisher: Springer Nature
ISBN: 3030212939
Category : Technology & Engineering
Languages : en
Pages : 398

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Book Description
This open access book describes modern applications of computational human modeling with specific emphasis in the areas of neurology and neuroelectromagnetics, depression and cancer treatments, radio-frequency studies and wireless communications. Special consideration is also given to the use of human modeling to the computational assessment of relevant regulatory and safety requirements. Readers working on applications that may expose human subjects to electromagnetic radiation will benefit from this book’s coverage of the latest developments in computational modelling and human phantom development to assess a given technology’s safety and efficacy in a timely manner. Describes construction and application of computational human models including anatomically detailed and subject specific models; Explains new practices in computational human modeling for neuroelectromagnetics, electromagnetic safety, and exposure evaluations; Includes a survey of modern applications for which computational human models are critical; Describes cellular-level interactions between the human body and electromagnetic fields.

Computational Modeling of Cognition and Behavior

Computational Modeling of Cognition and Behavior PDF Author: Simon Farrell
Publisher: Cambridge University Press
ISBN: 110710999X
Category : Psychology
Languages : en
Pages : 485

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Book Description
This book presents an integrated framework for developing and testing computational models in psychology and related disciplines. Researchers and students are given the knowledge and tools to interpret models published in their area, as well as to develop, fit, and test their own models.

Computational Modelling in Behavioural Neuroscience

Computational Modelling in Behavioural Neuroscience PDF Author: Dietmar Heinke
Publisher: Psychology Press
ISBN: 1135430039
Category : Psychology
Languages : en
Pages : 375

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Book Description
Classically, behavioural neuroscience theorizes about experimental evidence in a qualitative way. However, more recently there has been an increasing development of mathematical and computational models of experimental results, and in general these models are more clearly defined and more detailed than their qualitative counter parts. These new computational models can be set up so that they are consistent with both single neuron and whole-system levels of operation, allowing physiological results to be meshed with behavioural data – thus closing the gap between neurophysiology and human behaviour. There is considerable diversity between models with respect to the methodology of designing a model, the degree to which neurophysiological processes are taken into account and the way data (behavioural, electrophysiological, etc) constrains a model. This book presents examples of this diversity and in doing so represents the state-of-art in the field through a unique collection of papers from the world's leading researchers in the area of computational modelling in behavioural neuroscience. Based on talks given at the third Behavioural Brain Sciences Symposium, held at the Behavioural Brain Sciences Centre, University of Birmingham, in May 2007, the book appeals to a broad audience, from postgraduate students beginning to work in the field to experienced experimenters interested in an overview.

Computational Modelling of the Brain

Computational Modelling of the Brain PDF Author: Michele Giugliano
Publisher: Springer Nature
ISBN: 3030894398
Category : Medical
Languages : en
Pages : 361

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Book Description
This volume offers an up-to-date overview of essential concepts and modern approaches to computational modelling, including the use of experimental techniques related to or directly inspired by them. The book introduces, at increasing levels of complexity and with the non-specialist in mind, state-of-the-art topics ranging from single-cell and molecular descriptions to circuits and networks. Four major themes are covered, including subcellular modelling of ion channels and signalling pathways at the molecular level, single-cell modelling at different levels of spatial complexity, network modelling from local microcircuits to large-scale simulations of entire brain areas and practical examples. Each chapter presents a systematic overview of a specific topic and provides the reader with the fundamental tools needed to understand the computational modelling of neural dynamics. This book is aimed at experimenters and graduate students with little or no prior knowledge of modelling who are interested in learning about computational models from the single molecule to the inter-areal communication of brain structures. The book will appeal to computational neuroscientists, engineers, physicists and mathematicians interested in contributing to the field of neuroscience. Chapters 6, 10 and 11 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Principles of Computational Modelling in Neuroscience

Principles of Computational Modelling in Neuroscience PDF Author: David Sterratt
Publisher: Cambridge University Press
ISBN: 1139500791
Category : Medical
Languages : en
Pages : 403

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Book Description
The nervous system is made up of a large number of interacting elements. To understand how such a complex system functions requires the construction and analysis of computational models at many different levels. This book provides a step-by-step account of how to model the neuron and neural circuitry to understand the nervous system at all levels, from ion channels to networks. Starting with a simple model of the neuron as an electrical circuit, gradually more details are added to include the effects of neuronal morphology, synapses, ion channels and intracellular signalling. The principle of abstraction is explained through chapters on simplifying models, and how simplified models can be used in networks. This theme is continued in a final chapter on modelling the development of the nervous system. Requiring an elementary background in neuroscience and some high school mathematics, this textbook is an ideal basis for a course on computational neuroscience.

Computational Explorations in Cognitive Neuroscience

Computational Explorations in Cognitive Neuroscience PDF Author: Randall C. O'Reilly
Publisher: MIT Press
ISBN: 9780262650540
Category : Medical
Languages : en
Pages : 540

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Book Description
This text, based on a course taught by Randall O'Reilly and Yuko Munakata over the past several years, provides an in-depth introduction to the main ideas in the computational cognitive neuroscience. The goal of computational cognitive neuroscience is to understand how the brain embodies the mind by using biologically based computational models comprising networks of neuronlike units. This text, based on a course taught by Randall O'Reilly and Yuko Munakata over the past several years, provides an in-depth introduction to the main ideas in the field. The neural units in the simulations use equations based directly on the ion channels that govern the behavior of real neurons, and the neural networks incorporate anatomical and physiological properties of the neocortex. Thus the text provides the student with knowledge of the basic biology of the brain as well as the computational skills needed to simulate large-scale cognitive phenomena. The text consists of two parts. The first part covers basic neural computation mechanisms: individual neurons, neural networks, and learning mechanisms. The second part covers large-scale brain area organization and cognitive phenomena: perception and attention, memory, language, and higher-level cognition. The second part is relatively self-contained and can be used separately for mechanistically oriented cognitive neuroscience courses. Integrated throughout the text are more than forty different simulation models, many of them full-scale research-grade models, with friendly interfaces and accompanying exercises. The simulation software (PDP++, available for all major platforms) and simulations can be downloaded free of charge from the Web. Exercise solutions are available, and the text includes full information on the software.