Author: M. Sharon Stack
Publisher: Springer Science & Business Media
ISBN: 9780387980942
Category : Medical
Languages : en
Pages : 408

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Book Description
Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined, due to a continued inability to achieve detection of early (rather than advanced) stage disease and the lack of effective tumor-specific therapeutics. Ovarian carcinogenesis, invasion, and metastatic dissemination require a complex cascade of interrelated genetic, molecular, and biochemical events that regulate the neoplastic transition of normal ovarian surface epithelium. This updated second edition includes exciting new advances in ovarian cancer detection and treatment and provides an analysis of current research into aspects of malignant transformation, growth control, and metastasis. A more detailed understanding of these processes may ultimately translate into the development of novel approaches for the detection and control of ovarian cancer.

Author: F. Gentil
Publisher: Springer Science & Business Media
ISBN: 3642877559
Category : Medical
Languages : en
Pages : 268

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Book Description
The incidence of ovarian cancer has progressively increased during the past decade, and its mortality rate has followed a similar course. Conversely, in cancer of the uterine cervix, the mortality rate has diminished. Detection and early diag nosis have been the two responsible factors in achieving the decrease in the number of deaths occurring in cancer of the cervix. The revers~ is true in cancer of the ovary: diagnosis as a rule is only established late, when dissemination has already occurred, thus making the control of the disease much more difficult. Clinical staging thus far has not been in use at many centers, and it therefore becomes very difficult to compare results of treatment since we do not know the exact anatomical extent of the disease. Histopathological classification in cancer of the ovary is still a very controversial subject and a uniform terminology is urgently required. Management of patients with cancer of the ovary varies widely from one institu tion to another. There is no agreement as to how to treat an ovarian neoplasm; by surgery alone, or, by using radiation and chemotherapy as a complement to the operative treatment. In an effort to shed more light on these items, the Patient Care Committee of the UIce held this symposium, which was unique in the broadness of its scope pertaining to every phase of ovarian cancer.

Author: A. P. Bardos
Publisher: Nova Publishers
ISBN: 9781594540233
Category : Ovaries
Languages : en
Pages : 182

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Book Description
Ovarian cancer is cancer that begins in the cells that constitute the ovaries, including surface epithelial cells, germ cells, and the sex cord-stromal cells. Cancer cells that metastasize from other organ sites to the ovary (most commonly breast or colon cancers) are not then considered ovarian cancer. According to the American Cancer Society, ovarian cancer accounts for 4 percent of all cancers among women and ranks fifth as a cause of their deaths from cancer. The American Cancer Society statistics for ovarian cancer estimate that there will be 25,400 new cases and 14,300 deaths in 2003. The death rate for this disease has not changed much in the last 50 years. Unfortunately, almost 70 percent of women with the common epithelial ovarian cancer are not diagnosed until the disease is advanced in stage -- i.e., has spread to the upper abdomen (stage III) or beyond (stage IV). The 5-year survival rate for these women is only 15 to 20 percent, whereas the 5-year survival rate for stage I disease patients approaches 90 percent and for stage II disease patients approaches 70 percent. Ovarian tumors are named according to the type of cells the tumor started from and whether the tumor is benign or cancerous. The three main types of ovarian tumors are: Epithelial Tumors, Germ Cell Tumors and Stromal Tumors. This new book brings together new and leading-edge research from around the world.

Author: Rodney Reznek
Publisher: Cambridge University Press
ISBN: 1139460641
Category : Medical
Languages : en
Pages :

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Book Description
Ovarian cancer is not only the commonest but also the most lethal gynaecological malignancy, partly because the majority of patients present with advanced disease. Nevertheless, the management of patients with ovarian neoplasms has changed substantially recently, with improved survival due to better screening strategies, major advances in chemotherapy and the constantly evolving role of surgery. Optimal patient care is best achieved by a multidisciplinary team, with imaging playing a pivotal role. The explosion of technological developments in imaging in recent years has meant that all members of the team should understand the potential applications, limitations and advantages of evolving imaging techniques. Each volume in Contemporary Issues in Cancer Imaging - A Multidisciplinary Approach is edited by an expert guest editor with contributions from all members of the multidisciplinary team, thus bringing together expertise from many specialties to promote the understanding and application of modern imaging in overall patient management.

Author: Robert F. Ozols
Publisher: PMPH-USA
ISBN: 9781550090963
Category : Medical
Languages : en
Pages : 262

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Book Description
"Featuring more than 300 illustrations, the text covers pathology, biology, epidemiology, genetics, and screening through surgical management, the latest in chemotherapeutic regimens, and finally, palliative care"--P. [4] of cover.

Author: A. P. Bardos
Publisher: Nova Publishers
ISBN: 9781594540226
Category : Medical
Languages : en
Pages : 248

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Book Description
This new volume presents the latest research on therapies for ovarian cancer. Ovarian cancer is cancer that begins in the cells that constitute the ovaries, including surface epithelial cells, germ cells, and the sex cord-stromal cells. Cancer cells that metastasize from other organ sites to the ovary (most commonly breast or colon cancers) are not then considered ovarian cancer. According to the American Cancer Society, ovarian cancer accounts for 4 percent of all cancers among women and ranks fifth as a cause of their deaths from cancer. The American Cancer Society statistics for ovarian cancer estimate that there will be 25,400 new cases and 14,300 deaths in 2003. The death rate for this disease has not changed much in the last 50 years. Unfortunately, almost 70 percent of women with the common epithelial ovarian cancer are not diagnosed until the disease is advanced in stage -- i.e., has spread to the upper abdomen (stage III) or beyond (stage IV). The 5-year survival rate for these women is only 15 to 20 percent, whereas the 5-year survival rate for stage I disease patients approaches 90 percent and for stage II disease patients approaches 70 percent. Ovarian tumors are named according to the type of cells the tumor started from and whether the tumor is benign or cancerous. The three main types of ovarian tumors are: Epithelial Tumors, Germ Cell Tumors and Stromal Tumors.

Author: Robert E. Bristow
Publisher: CRC Press
ISBN: 1482236958
Category : Medical
Languages : en
Pages : 437

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Book Description
Updated and expanded, the third edition of Surgery for Ovarian Cancer focuses on essential techniques for the effective management of ovarian cancer. It reflects the most contemporary science and surgical applications for the management of patients with ovarian cancer and related peritoneal surface malignancies. This new edition takes a step-by-step approach and includes new intraoperative photographs and videos illustrating surgical procedures. It is principally devoted to the technical aspects of cytoreductive surgery, with chapters divided according to anatomic region. The chapters cover relevant anatomical considerations, surgical challenges specific to each region, and operative approaches and techniques favored by the authors. The list of contributing authors has been expanded from the previous edition and includes international and world-renowned experts from the fields of gynecologic oncology and surgical oncology. The topics of minimally invasive surgery, secondary cytoreduction, palliative surgery, and postoperative care are also covered in detail. New to the third edition are chapters on preoperative risk stratification, regional therapeutics and peritonectomy procedures, and quality assurance relating to ovarian cancer surgery. This comprehensive text is essential reading for all practitioners working with patients with ovarian cancers.

Author: Eric Pujade-Lauraine
Publisher: Springer
ISBN: 3319321102
Category : Medical
Languages : en
Pages : 286

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Book Description
This book provides an overview of the latest developments in the concepts and management of ovarian cancer. The new data presented throughout opens the way to radically different therapeutic approaches. Surgery remains the core of ovarian cancer treatment, but its ultimate goal and the standard surgical procedure have evolved, giving rise to the question of how to label expert centers for debulking surgery. Neo-adjuvant chemotherapy is becoming more popular and is also a new field for testing novel drug combinations. Over recent years, ovarian cancer management has embraced molecular biology. It is now more correct to talk about cancers of the ovary rather than ovarian cancer, since it is not a unique disease but several entities with different molecular drivers. The significant advances in drugs targeting the microenvironment or the tumor cell DNA repair mechanisms are presented in detail together with exciting future perspectives. All these advances would not have been possible without collaborative groups such as the GINECO group in France and their integration in wider clinical research networks at the European (ENGOT) and international (GCIG) level.

Author: Hugh R.K. Barber
Publisher: Springer Science & Business Media
ISBN: 1461392322
Category : Medical
Languages : en
Pages : 362

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Book Description
Now in its third edition! Ovarian Carcinoma is an invaluable source of information because it gives a complete overview of all aspects: histologic classification, FIGO staging, tumor markers, symptoms, diagnosis, operative treatment, chemotherapy, radiation therapy, complications such as pregnancy and AIDS, biological response modifiers and the status of clinical trials. The new chapter on biologic response modification is especially noteworthy since it reports on new developments now being tested in clinical trials. All the other chapters have been expanded and updated, too. At the same time, the author has kept his clear, readable style that makes the book easy to understand. The contents are based on actual clinical experience and thus extremely practical.

Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309380464
Category : Medical
Languages : en
Pages : 397

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Book Description
In an era of promising advances in cancer research, there are considerable and even alarming gaps in the fundamental knowledge and understanding of ovarian cancer. Researchers now know that ovarian cancer is not a single disease-several distinct subtypes exist with different origins, risk factors, genetic mutations, biological behaviors, and prognoses. However, persistent questions have impeded progress toward improving the prevention, early detection, treatment, and management of ovarian cancers. Failure to significantly improve morbidity and mortality during the past several decades is likely due to several factors, including the lack of research being performed by specific disease subtype, lack of definitive knowledge of the cell of origin and disease progression, and incomplete understanding of genetic and non-genetic risk factors. Ovarian Cancers examines the state of the science in ovarian cancer research, identifies key gaps in the evidence base and the challenges to addressing those gaps, considers opportunities for advancing ovarian cancer research, and examines avenues for translation and dissemination of new findings and communication of new information to patients and others. This study makes recommendations for public- and private-sector efforts that could facilitate progress in reducing the incidence of morbidity and mortality from ovarian cancers.