Can Precision Medicine Be Personal; Can Personalized Medicine Be Precise? PDF Download
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Author: Yechiel Michael Barilan
Publisher: Oxford University Press
ISBN: 0198863462
Category : Medical ethics
Languages : en
Pages : 353
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Book Description
The book provides a multidisciplinary and interdisciplinary discussion of the ethos and ethics of precision / personal medicine, involving scientists who have shaped the field, in dialogue with ethicists, social scientists and philosophers of science.
Author: Yechiel Michael Barilan
Publisher: Oxford University Press
ISBN: 0198863462
Category : Medical ethics
Languages : en
Pages : 353
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Book Description
The book provides a multidisciplinary and interdisciplinary discussion of the ethos and ethics of precision / personal medicine, involving scientists who have shaped the field, in dialogue with ethicists, social scientists and philosophers of science.
Author: Yechiel Michael Barilan
Publisher:
ISBN: 9780191895913
Category : Medical ethics
Languages : en
Pages : 321
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Book Description
Providing a multidisciplinary and interdisciplinary discussion of the ethos and ethics of precision/personal medicine, this book presents scientists who have shaped the field, in dialogue with ethicists, social scientists and philosophers of science.
Author: Ernst R. Berndt
Publisher: University of Chicago Press
ISBN: 022661106X
Category : Business & Economics
Languages : en
Pages : 361
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Book Description
Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.
Author: Kristin Ciriello Pothier
Publisher: John Wiley & Sons
ISBN: 1118792122
Category : Medical
Languages : en
Pages : 228
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Book Description
The author uses decades of experience and interviews with experts in precision medicine to explain past, present, and future of precision medicine. She reviews the full continuum of personalizing precision medicine, including diagnostics, therapeutics, big data, supportive care, regulation, and reimbursement and innovation in precision medicine worldwide. • Combines a unique cross section of history, current technologies, and future directions for how precision medicine has and will affect people worldwide • Reviews precision medicine around the world, including the US, China, Japan, the Middle East, India, Europe, and Latin America • Discusses a number of diseases areas – cancer, cardiovascular, neurodegenerative, infectious disease, pain, immunology, rare diseases • Includes information and quotes from over 100 interviews with key industry experts in biotech, pharma, informatics, diagnostics, health providers, advocacy groups, and more. • Includes stories illustrating current issues and future promises in precision medicine for a human touch
Author: Jochen Vollmann
Publisher: Routledge
ISBN: 1317033728
Category : Medical
Languages : en
Pages : 291
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Book Description
In recent times, the phrase ’personalised medicine’ has become the symbol of medical progress and a label for better health care in the future. However, a controversial debate has developed around whether these promises of better, more personal and more cost-efficient medicine are realistic. This book brings together leading researchers from across Europe and North America, from both normative and empirical disciplines, who take a more critical view of the often encountered hype associated with personalised medicine. Partially drawing on a four year collaborative research project funded by the German Ministry for Education and Research, the book presents a multidisciplinary debate on the current state of research on the ethical, legal and social implications of personalised medicine. At a time when future health care is a topic of much discussion, this book provides valuable policy recommendations for the way forward. This study will be of interest to researchers from various disciplines including philosophy, bioethics, law and social sciences.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309222222
Category : Medical
Languages : en
Pages : 142
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Book Description
Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.
Author: Y. Michael Barilan
Publisher: Oxford University Press
ISBN: 0192608681
Category : Medical
Languages : en
Pages : 353
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Book Description
People have always sought medical care that is tailored to every individual patient. Alongside with the historical development of institutions of care, the vision of personal and 'holistic' care persisted. Patient-centred medicine, interpersonal communication and shared decision making have become central to medical practice and services. This evolving vision of 'personalized medicine' is in the forefront of medicine, creating debates among ethicists, philosophers and sociologists of medicine about the nature of disease and the definition of wellness, the impact on the daily life of patients, as well as its implications on low-income countries. Is increased 'precision' also an improvement on the personal aspects of care or erosion of privacy? Do 'precise' and 'personalized' approach marginalize public health, and can this care be personalized without attention to culture, economy and society? The book provides a multidisciplinary and interdisciplinary discussion of the ethos and ethics of precision/personal medicine, involving scientists who have shaped the field, in dialogue with ethicists, social scientists and philosophers of science. The contributing scholars come from all over the world and from different cultural backgrounds providing reflective perspectives of history of ideas, critical theory and technology assessment, together with the actual work done by pioneers in the field. It explores issues such as global justice, gender, public health, pharmaceutical industry, international law and religion, and explores themes discussed in relation to personalized medicine such as new-born screening and disorders of consciousness. This book will be of interest to academicians in bioethics, history of medicine, social sciences of medicine as well as general educated readers.
Author: Charles Rivière
Publisher: Springer Nature
ISBN: 3030242439
Category : Medical
Languages : en
Pages : 346
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Book Description
This open access book describes and illustrates the surgical techniques, implants, and technologies used for the purpose of personalized implantation of hip and knee components. This new and flourishing treatment philosophy offers important benefits over conventional systematic techniques, including component positioning appropriate to individual anatomy, improved surgical reproducibility and prosthetic performance, and a reduction in complications. The techniques described in the book aim to reproduce patients’ native anatomy and physiological joint laxity, thereby improving the prosthetic hip/knee kinematics and functional outcomes in the quest of the forgotten joint. They include kinematically aligned total knee/total hip arthroplasty, partial knee replacement, and hip resurfacing. The relevance of available and emerging technological tools for these personalized approaches is also explained, with coverage of, for example, robotics, computer-assisted surgery, and augmented reality. Contributions from surgeons who are considered world leaders in diverse fields of this novel surgical philosophy make this open access book will invaluable to a wide readership, from trainees at all levels to consultants practicing lower limb surgery
Author: Britta Chongkol van Beers
Publisher: Cambridge University Press
ISBN: 1108473911
Category : Law
Languages : en
Pages : 321
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Book Description
Asks whether personalised medicine is superior to 'one-size-fits-all' treatment. Does it elevate individual choice above the common good?
Author: Kewal K. Jain
Publisher: Humana Press
ISBN: 1493925539
Category : Medical
Languages : en
Pages : 762
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Book Description
Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.
