Calorie Restriction, Aging and Longevity

Calorie Restriction, Aging and Longevity PDF Author: Arthur V. Everitt
Publisher: Springer Science & Business Media
ISBN: 9789048185566
Category : Medical
Languages : en
Pages : 323

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Book Description
Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible in humans because of their long survival. Studies over two to six years in healthy adult humans have, however, shown that a 20% reduction in food or calorie intake slows many indices of normal and disease-related aging. Thus, it is widely believed that long-term reduction in calorie or food intake will delay the onset of age-related diseases such as heart disease, diabetes and cancer, and so prolong life. Over the last 20 or more years there has been a progressive rise in food intake in many countries of the world, accompanied by a rising incidence of obesity. Thus our increasing food and calorie intake has been linked to the rising incidence of cardiovascular disease and diabetes in early adult life. It is accepted that overeating, accompanied by reduced physical exercise, will lead to more age-related diseases and shortening of life-span. The answer is to reduce our calorie intake, improve our diet, and exercise more. But calorie restriction is extremely difficult to maintain for long periods. How then can we solve this problem? Edited by a team of highly distinguished academics, this book provides the latest information on the beneficial effects of calorie restriction on health and life-span. This book brings us closer to an understanding at the molecular, cellular and whole organism level of the way forward.

Calorie Restriction, Aging and Longevity

Calorie Restriction, Aging and Longevity PDF Author: Arthur V. Everitt
Publisher: Springer Science & Business Media
ISBN: 9789048185566
Category : Medical
Languages : en
Pages : 323

Get Book

Book Description
Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible in humans because of their long survival. Studies over two to six years in healthy adult humans have, however, shown that a 20% reduction in food or calorie intake slows many indices of normal and disease-related aging. Thus, it is widely believed that long-term reduction in calorie or food intake will delay the onset of age-related diseases such as heart disease, diabetes and cancer, and so prolong life. Over the last 20 or more years there has been a progressive rise in food intake in many countries of the world, accompanied by a rising incidence of obesity. Thus our increasing food and calorie intake has been linked to the rising incidence of cardiovascular disease and diabetes in early adult life. It is accepted that overeating, accompanied by reduced physical exercise, will lead to more age-related diseases and shortening of life-span. The answer is to reduce our calorie intake, improve our diet, and exercise more. But calorie restriction is extremely difficult to maintain for long periods. How then can we solve this problem? Edited by a team of highly distinguished academics, this book provides the latest information on the beneficial effects of calorie restriction on health and life-span. This book brings us closer to an understanding at the molecular, cellular and whole organism level of the way forward.

Calorie Restriction, Aging and Longevity

Calorie Restriction, Aging and Longevity PDF Author: Arthur V. Everitt
Publisher: Springer
ISBN: 9789048185573
Category : Medical
Languages : en
Pages : 323

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Book Description
Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible in humans because of their long survival. Studies over two to six years in healthy adult humans have, however, shown that a 20% reduction in food or calorie intake slows many indices of normal and disease-related aging. Thus, it is widely believed that long-term reduction in calorie or food intake will delay the onset of age-related diseases such as heart disease, diabetes and cancer, and so prolong life. Over the last 20 or more years there has been a progressive rise in food intake in many countries of the world, accompanied by a rising incidence of obesity. Thus our increasing food and calorie intake has been linked to the rising incidence of cardiovascular disease and diabetes in early adult life. It is accepted that overeating, accompanied by reduced physical exercise, will lead to more age-related diseases and shortening of life-span. The answer is to reduce our calorie intake, improve our diet, and exercise more. But calorie restriction is extremely difficult to maintain for long periods. How then can we solve this problem? Edited by a team of highly distinguished academics, this book provides the latest information on the beneficial effects of calorie restriction on health and life-span. This book brings us closer to an understanding at the molecular, cellular and whole organism level of the way forward.

The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease

The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease PDF Author: Hae-Young Chung
Publisher: MDPI
ISBN: 3039438379
Category : Science
Languages : en
Pages : 186

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Book Description
Recent biochemical studies indicate that calorie restriction (CR) is a widely accepted method for anti-aging intervention. CR and intermittent fasting (IF), which involves reduced calories but proper nutritional intake during specific periods, are interventions that can consistently promote health benefits, delay biological aging, and extend both average and maximal lifespan. Furthermore, CR can modulate age-related diseases such as Alzheimer’s disease, atherosclerosis, diabetes, obesity, cancer, and others. Advances in omics technologies have provided a technical breakthrough that enabled the investigation of DNA, RNA, proteins, and other cellular molecules and their comprehensive interactions in a biological context. Nowadays, it is possible to analyze and integrate biological processes that occur in aging systems at the molecular level using state-of-the-art techniques such as next-generation sequencing (NGS), proteomics, lipidomics, metabolomics, and epigenomics. Omics technology and systems gerontology provide predictive information on CR effects, molecular mechanisms, and pathways underlying the anti-aging actions of CR and IF. This Special Issue, “The effects of calorie restriction and intermittent fasting on health and disease”, focuses on the effects of calorie restriction and intermittent fasting on age-related inflammation, autophagy, metabolism, longevity, mitochondrial function, and age-related diseases.

The Longevity Diet

The Longevity Diet PDF Author: Brian M. Delaney
Publisher: Da Capo Lifelong Books
ISBN: 1600940382
Category : Health & Fitness
Languages : en
Pages : 354

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Book Description
Presents an introduction to the calorie restriction diet plan, discussing how it slows the aging process, reduces the risk of disease, and maximizes health, including recipes for main and side dishes.

Caloric Restriction: A Key to Understanding and Modulating Aging

Caloric Restriction: A Key to Understanding and Modulating Aging PDF Author: E.J. Masoro
Publisher: Elsevier
ISBN: 0080528422
Category : Technology & Engineering
Languages : en
Pages : 193

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Book Description
For many years, it has been known that when rats and mice are given a reduced amount of food, their life span is increased and they remain healthy and vigorous at advanced ages. What is the reason for this change in the usual pattern of aging? The evidence is overwhelming that the life extension results from a slowing of aging processes. And the factor responsible is the decrease in caloric intake. The obvious question: How does this factor work? A good question - and the reason that research on the anti-aging action of caloric restriction is today one of the most studied research areas in biological gerontology. For it is felt that if the biological mechanisms of the anti-aging action of caloric restriction can be uncovered, we would gain an understanding of the basic nature of aging processes, which would, in turn, yield possible interventions in human aging. This book aims to provide the growing number of researchers in this field (faculty, postdoctoral trainees, and graduate students) with a detailed knowledge of what is known about caloric restriction within the frame of gerontology, as well as insights on future of this field.

Nutrition, Food and Diet in Ageing and Longevity

Nutrition, Food and Diet in Ageing and Longevity PDF Author: Suresh I. S. Rattan
Publisher: Springer Nature
ISBN: 3030830179
Category : Family & Relationships
Languages : en
Pages : 643

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Book Description
This edited volume is a compilation of 30 articles discussing what constitutes food for health and longevity. The aim is to provide up-to-date information, insights, and future tendencies in the ongoing scientific research about nutritional components, food habits and dietary patterns in different cultures. The health-sustaining and health-promoting effects of food are certainly founded in its overall composition of macronutrients and micronutrients. However, the consumption of these nutrients is normally in the form of raw or prepared food from the animal and plant sources. The book is divided into four parts and a conclusion, and successfully convenes the well-established information and knowledge, along with the personal views of a diversified group of researchers and academicians on the multifaceted aspects of nutrition, food and diet. The first part reviews the scientific information about proteins, carbohydrates, fats and oils, micronutrients, pro- and pre-biotics, and hormetins, along with a discussion of the evolutionary principles and constraints about what is optimal food, if any. The second part discusses various kinds of foods and food supplements with respect to their claimed benefits for general health and prevention of some diseases. The third part brings in the cultural aspects, such as what are the principles of healthy eating according to the traditional Chinese and Indian systems, what is the importance of mealing times and daily rhythms, and how different cultures have developed different folk wisdoms for eating for health, longevity and immortality. In the part four, various approaches which are either already in practice or are still in the testing and research phases are discussed and evaluated critically, for example intermittent fasting and calorie restriction, food-based short peptides, senolytics, Ayurvedic compounds, optimal food for old people, and food for the prevention of obesity and other metabolic disorders. The overreaching aim of this book is to inform, inspire and encourage students, researchers, educators and medical health professionals thinking about food and food habits in a holistic context of our habits, cultures and patterns. Food cannot be reduced to a pill of nutritional components. Eating food is a complex human behavior culturally evolved over thousands of years. Perhaps the old adage “we are what we eat” needs to be modified to “we eat what we are”.

The Retardation of Aging and Disease by Dietary Restriction

The Retardation of Aging and Disease by Dietary Restriction PDF Author: Richard Weindruch
Publisher: Charles C Thomas Pub Limited
ISBN: 9780398054960
Category : Health & Fitness
Languages : en
Pages : 436

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Book Description


Providing Healthy and Safe Foods As We Age

Providing Healthy and Safe Foods As We Age PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309158834
Category : Medical
Languages : en
Pages : 192

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Book Description
Does a longer life mean a healthier life? The number of adults over 65 in the United States is growing, but many may not be aware that they are at greater risk from foodborne diseases and their nutritional needs change as they age. The IOM's Food Forum held a workshop October 29-30, 2009, to discuss food safety and nutrition concerns for older adults.

Longevity Diet

Longevity Diet PDF Author: Valter Longo
Publisher:
ISBN: 9781405933940
Category : Aging
Languages : en
Pages : 288

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Book Description
The internationally renowned, clinically tested, revolutionary diet program to lose weight, fight disease, and live a longer, healthier life. Can what you eat determine how long, and how well, you live? The clinically proven answer is yes, and The Longevity Diet is easier to follow than you'd think. The culmination of 25 years of research on ageing, nutrition, and disease across the globe, this unique combination of an everyday diet and fasting-mimicking diet (FMD) to be done only 3-4 times per year lays out a simple solution to living to a healthy old age through nutrition. FMD does away with the misery and starvation most of us experience while fasting and helps you reap all the beneficial health effects of a restrictive diet while avoiding the negative stressors, like low energy and sleeplessness. Valter Longo, Director of the Longevity Institute at USC and the Program on Longevity and Cancer at IFOM in Milan, developed THE FMD after making a series of remarkable discoveries in mice and humans indicating that specific diets can activate stem cells and promote regeneration and rejuvenation in multiple organs to reduce the risk for diabetes, cancer, Alzheimer's and heart disease. Longo's simple pescatarian daily eating plan and the periodic, fasting-mimicking techniques can both yield impressive results. Low in proteins and sugars and rich in healthy fats and plant-based foods, The Longevity Diet is clinically proven to help you: Lose weight and reduce abdominal fat Make simple changes which can extend the healthy lifespan Prevent age-related muscle and bone loss Build your resistance to diabetes, cardiovascular disease, Alzheimer's and cancer Longo's healthy, life span-extending plan is based on an easy-to-adopt pescatarian plan along with the fasting-mimicking diet 4 times a year, and just 5 days at a time. The Longevity Diet is the key to living a longer, healthier, and more fulfilled life.

Eat Less, Live Longer - Your Practical Guide to Calorie Restriction with Optimal Nutrition

Eat Less, Live Longer - Your Practical Guide to Calorie Restriction with Optimal Nutrition PDF Author: Anca Ioviţă
Publisher: Anca Ioviţă
ISBN: 8822878701
Category : Health & Fitness
Languages : en
Pages : 140

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Book Description
During my third year of medical school I stumbled upon an online article about calorie restriction with optimal nutrition. I read about an apparently simple diet intervention that prolonged the average and maximum lifespan of laboratory animals such as yeast, fruit flies, worms and mice. At that time, I wasn’t aware that such experiments were already done on non-human primates too. Honestly, I dismissed it as a curiosity, an intervention that could have some effect in simple organisms such as fruit flies, but something which would never work in complex beings like us. It just seemed too good to be true. Time passed and proved me wrong. Given an early childhood fascination with the limits of life extension, I studied engineering and medicine in an attempt to radically prolong human lifespan. After a short stint of research in neural prosthetics in a German lab, I realized implanting artificial devices into the human body is not a long-term solution. I returned home where I started the medical residency in geriatrics, the branch of medicine specialized in age-associated diseases. A funny thing happened then. Reading about theories of aging is one thing. Daily caring for people 3-4 times your age is a completely different thing and I started to connect the dots. I noticed some people aged like wine and others aged like vinegar. According to their skinny frames and detailed lifetime stories, it looked like calorie intake had something to do with it. That’s how I got started in typing the first words for this book. ********* TABLE OF CONTENTS *********** Introduction Basic Principles of Calorie Restriction with Optimal Nutrition What You Will NOT Find in this Book How Should You Use This Book? Less is More for Rodents. Is It the Same for Humans? Indications and Contraindications of Calorie Restriction with Optimal Nutrition Medical Tests for Monitoring Calorie Restriction with Optimal Nutrition How Do You Choose Quality Food? Where to Source Quality Food When Looks May Deceive You Which Food Choices Provide the Most Nutrients for the Least Amount of Calories? Beverages The Smoothie Formula The Joys of Vegetables The Basic Soup The Wonders of Roe How to Serve Fish Sushi – the Perfect Ocean Food Edible Mushrooms Pates, Dips and Spreads Animal Products and Offal A Small Guide to Culinary Herbs and Spices The Comfort of Herbal Teas Desserts A Raw Vegan Cake Eating out When Restricting Calories How to Turn Quality Ingredients into Amazing Dishes Where Can You Source Nutritious Low-Calorie Recipes? Cooking Utensils or Tools of the Trade Calorie Restriction for the Long Term The Ups and Downs of Fasting How to Implement Calorie Restriction as a Full-Time Professional The Practical Shopping List How to Choose Dietary Supplements Are There Alternatives to Calorie Restriction? The End Acknowledgments Bibliography