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Author: Suzanne H. Reuben
Publisher: DIANE Publishing
ISBN: 1437934218
Category : Health & Fitness
Languages : en
Pages : 240
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Book Description
Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.
Author: Suzanne H. Reuben
Publisher: DIANE Publishing
ISBN: 1437934218
Category : Health & Fitness
Languages : en
Pages : 240
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Book Description
Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.
Author: Andrew Teasdale
Publisher: John Wiley & Sons
ISBN: 1119551218
Category : Medical
Languages : en
Pages : 548
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Book Description
Learn to implement effective control measures for mutagenic impurities in pharmaceutical development In Mutagenic Impurities: Strategies for Identification and Control, distinguished chemist Andrew Teasdale delivers a thorough examination of mutagenic impurities and their impact on the pharmaceutical industry. The book incorporates the adoption of the ICH M7 guideline and focuses on mutagenic impurities from both a toxicological and analytical perspective. The editor has created a primary reference for any professional or student studying or working with mutagenic impurities and offers readers a definitive narrative of applicable guidelines and practical, tested solutions. It demonstrates the development of effective control measures, including chapters on the purge tool for risk assessment. The book incorporates a discussion of N-Nitrosamines which was arguably the largest mutagenic impurity issue ever faced by the pharmaceutical industry, resulting in the recall of Zantac and similar drugs resulting from N-Nitrosamine contamination. Readers will also benefit from the inclusion of: A thorough introduction to the development of regulatory guidelines for mutagenic and genotoxic impurities, including a historical perspective on the development of the EMEA guidelines and the ICH M7 guideline An exploration of in silico assessment of mutagenicity, including use of structure activity relationship evaluation as a tool in the evaluation of the genotoxic potential of impurities A discussion of a toxicological perspective on mutagenic impurities, including the assessment of mutagenicity and examining the mutagenic and carcinogenic potential of common synthetic reagents Perfect for chemists, analysts, and regulatory professionals, Mutagenic Impurities: Strategies for Identification and Control will also earn a place in the libraries of toxicologists and clinical safety scientists seeking a one-stop reference on the subject of mutagenic impurity identification and control.
Author: Joel Timyan
Publisher:
ISBN:
Category : Tree crops
Languages : en
Pages : 440
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Book Description
Author: Andrew Teasdale
Publisher: John Wiley & Sons
ISBN: 0470934751
Category : Medical
Languages : en
Pages : 455
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Book Description
This book examines genotoxic impurities and their impact on the pharmaceutical industry. Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately control genotoxic impurities, thus aiding the reader to develop effective control measures. An opening section covers the development of guidelines and the threshold of toxicological concern (TTC) and is followed by a section on safety aspects, including safety tests in vivo and vitro, and data interpretation. The second section addresses the risk posed by genotoxic impurities from outside sources and from mutagens within DNA. In the final section, the book deals with the quality perspective of genotoxic impurities focused on two critical aspects, the first being the analysis and the second how to practically evaluate the impurities.
Author:
Publisher:
ISBN:
Category : Continental shelf
Languages : en
Pages : 596
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Book Description
Author: Antonella Leone
Publisher: MDPI
ISBN: 3039432087
Category : Science
Languages : en
Pages : 230
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Book Description
This Special Issue of Marine Drugs gathers recent investigations on the proteomes, metabolomes, transcriptomes, and the associated microbiomes of marine jellyfish and polyps, including bioactivity studies of their compounds and more generally, on their biotechnological potential, witnessing the increasingly recognized importance of Cnidaria as a largely untapped Blue Growth resource for new drug discovery. These researches evoke the outstanding ecological importance of cnidarians in marine ecosystems worldwide, calling for a global monitoring and conservation of marine biodiversity, so that the biotechnological exploitation of marine living resources will be carried out to conserve and sustainably use the natural capital of the oceans.
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9789241545372
Category : Health & Fitness
Languages : en
Pages : 392
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Book Description
This is the second volume in a series of monographs which are intended to promote information exchange and international harmonised standards for the quality control and use of herbal medicines. It contains scientific information on 30 selected plants, and each entry includes a pharmacopoeial summary for quality assurance purposes, information on its clinical application and sections on contraindications, pharmacology, safety issues, and dosage forms. It provides two cumulative indexes with entries in alphabetical order by plant name and according to the plant material of interest.
Author: Travis Rayne Pickering
Publisher:
ISBN:
Category : Africa
Languages : en
Pages : 328
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Book Description
Taphonomy, the study of the processes leading to the fossilization of organic remains, is one of the most important avenues of inquiry in human origins research. Breathing Life into Fossils is a major contribution to taphonomic studies in paleoanthropology and natural history. This book emanates from a Stone Age Institute conference celebrating the life and career of naturalist Bob Brain, a pioneer in bringing taphonomic perspectives to human evolutionary studies. Contributions by leading researchers provide a state-of-the art look at the maturing field of taphonomy and the unique perspectives it provides to research into human origins. This important volume reveals approaches taken to the study of bone accumulations at prehistoric sites in Africa, Eurasia, and America, and provides fascinating insights into patterns produced by carnivores, by hunter-gatherers, and by our human ancestors.
Author: B. Mohan Kumar
Publisher: Springer Science & Business Media
ISBN: 9789400716308
Category : Technology & Engineering
Languages : en
Pages : 310
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Book Description
Tree based production systems abound especially in the tropics. Despite the pervasiveness of such multipurpose “trees-outside-forest” resources, they have not attracted adequate attention in the development paradigms of many nation states. These multispecies production systems impact the ecosystem processes favourably. Yet, our understanding of the diversity attributes and carbon dynamics under agroforestry is not adequate. This book focuses on the role of multispecies production systems involving tree and crop species as a means for carbon sequestration and thereby reduce atmospheric carbon dioxide levels. Sixteen chapters organized into three broad sections titled: Measurement and Estimation, Agrobiodiversity and Tree Management, and Policy and Socioeconomic Aspects represent a cross section of the opportunities and challenges in current research and emerging issues in harnessing carbon sequestration potential of agroforestry systems.
Author: Thomas William Merrick
Publisher: National Academies Press
ISBN:
Category : Social Science
Languages : en
Pages : 259
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Book Description
