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Author:
Publisher: Academic Press
ISBN: 0128013192
Category : Science
Languages : en
Pages : 358
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Book Description
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume, concentrates on the brain transcriptome. Brings together cutting-edge research on the brain transcriptome
Author:
Publisher: Academic Press
ISBN: 0128013192
Category : Science
Languages : en
Pages : 358
Get Book
Book Description
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume, concentrates on the brain transcriptome. Brings together cutting-edge research on the brain transcriptome
Author: Jiajia Zhu
Publisher: Frontiers Media SA
ISBN: 2832500978
Category : Science
Languages : en
Pages : 114
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Book Description
Author:
Publisher: Elsevier
ISBN: 0444538852
Category : Science
Languages : en
Pages : 376
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Book Description
How does the genome, interacting with the multi-faceted environment, translate into the development by which the human brain achieves its astonishing, adaptive array of cognitive and behavioral capacities? Why and how does this process sometimes lead to neurodevelopmental disorders with a major, lifelong personal and social impact? This volume of Progress in Brain Research links findings on the structural development of the human brain, the expression of genes in behavioral and cognitive phenotypes, environmental effects on brain development, and developmental processes in perception, action, attention, cognitive control, social cognition, and language, in an attempt to answer these questions. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Author: Tomas Paus
Publisher: Springer Science & Business Media
ISBN: 3642364500
Category : Medical
Languages : en
Pages : 198
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Book Description
Is Newton’s brain different from Rembrandt’s? Does a mother’s diet during pregnancy impact brain growth? Do adolescent peers leave a signature in the social brain? Does the way we live in our middle years affect how our brains age? To answer these and many other questions, we can now turn to population neuroscience. Population neuroscience endeavors to identify environmental and genetic factors that shape the function and structure of the human brain; it uses the tools and knowledge of genetics (and the “omics” sciences), epidemiology and neuroscience. This text attempts to provide a bridge spanning these three disciplines so that their practitioners can communicate easily with each other when working together on large-scale imaging studies of the developing, mature and aging brain. By understanding the processes driving variations in brain function and structure across individuals, we will also be able to predict an individual’s risk of (or resilience against) developing a brain disorder. In the long term, the hope is that population neuroscience will lay the foundation for personalized preventive medicine and, in turn, reduce the burden associated with complex, chronic disorders of brain and body.
Author: National Academies Of Sciences Engineeri
Publisher: National Academies Press
ISBN: 9780309265102
Category : Medical
Languages : en
Pages :
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Book Description
Accumulating evidence gathered over the past three decades has demonstrated a biological basis for differences between men and women with respect to clinical features and treatment responses to several neuropsychiatric, neurodevelopmental, and neurodegenerative disorders. Dramatic sex differences have also been identified in the brain transcriptomes of individuals with multiple brain disorders, including depression, posttraumatic stress disorder, and autism. The brain transcriptome includes all of the messenger RNA as well as the non-protein-coding RNA molecules expressed in brain tissue and thus represents gene activity. To explore these sex-based transcriptomic differences further, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders hosted a workshop on September 23, 2020, titled Sex Differences in Brain Disorders: Emerging Transcriptomic Evidence and Implications for Therapeutic Development. The workshop brought together a broad spectrum of stakeholders to share cutting-edge emerging evidence, discuss challenges, and identify future opportunities and potential directions. This publication summarizes the presentation and discussion of the workshop.
Author: Nancy C. Andreasen
Publisher:
ISBN: 9780195167283
Category : Génome humain
Languages : en
Pages : 392
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Book Description
Here, leading neuroscientist Nancy Andreasen offers a state-of-the-art look at what we know about the human brain and the human genome--and shows how these two vast branches of knowledge are coming together in a boldly ambitious effort to conquer mental illness. Andreasen gives us an engaging and readable description of how it all works---from billions of neurons, to the tiny thalamus, to the moral monitor in our prefrontal cortex. She shows the progress made in mapping the human genome, whose 30,000 to 40,000 genes are almost all active in the brain. We read gripping stories of the people who develop mental illness, the friends and relatives who share their suffering, the physicians who treat them, and the scientists who study them so that better treatments can be found. Four major disorders are covered--schizophrenia, manic depression, anxiety disorders, and dementia--revealing what causes them and how they affect the mind and brain. Finally, the book shows how the powerful tools of genetics and neuroscience will be combined during the next decades to build healthier brains and minds. By revealing how combining genome mapping with brain mapping can unlock the mysteries of mental illness, Andreasen offers a remarkably fresh perspective on these devastating diseases.
Author: Alessandro Cellerino
Publisher: Springer
ISBN: 8876426426
Category : Mathematics
Languages : en
Pages : 188
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Book Description
The goal of this book is to be an accessible guide for undergraduate and graduate students to the new field of data-driven biology. Next-generation sequencing technologies have put genome-scale analysis of gene expression into the standard toolbox of experimental biologists. Yet, biological interpretation of high-dimensional data is made difficult by the lack of a common language between experimental and data scientists. By combining theory with practical examples of how specific tools were used to obtain novel insights in biology, particularly in the neurosciences, the book intends to teach students how to design, analyse, and extract biological knowledge from transcriptome sequencing experiments. Undergraduate and graduate students in biomedical and quantitative sciences will benefit from this text as well as academics untrained in the subject.
Author: Sebastian Seung
Publisher: Houghton Mifflin Harcourt
ISBN: 0547508182
Category : Psychology
Languages : en
Pages : 389
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Book Description
The audacious effort to map the brain--and along with it mental afflictions, from autism to schizophrenia--by a rising star in neuroscience.
Author: Juergen K Mai
Publisher: Academic Press
ISBN: 0080921302
Category : Science
Languages : en
Pages : 1429
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Book Description
The previous two editions of the Human Nervous System have been the standard reference for the anatomy of the central and peripheral nervous system of the human. The work has attracted nearly 2,000 citations, demonstrating that it has a major influence in the field of neuroscience. The 3e is a complete and updated revision, with new chapters covering genes and anatomy, gene expression studies, and glia cells. The book continues to be an excellent companion to the Atlas of the Human Brain, and a common nomenclature throughout the book is enforced. Physiological data, functional concepts, and correlates to the neuroanatomy of the major model systems (rat and mouse) as well as brain function round out the new edition. Adopts standard nomenclature following the new scheme by Paxinos, Watson, and Puelles and aligned with the Mai et al. Atlas of the Human Brain (new edition in 2007) Full color throughout with many new and significantly enhanced illustrations Provides essential reference information for users in conjunction with brain atlases for the identification of brain structures, the connectivity between different areas, and to evaluate data collected in anatomical, physiological, pharmacological, behavioral, and imaging studies
Author: Albert Cheung-Hoi Yu
Publisher: Springer
ISBN: 3319945939
Category : Medical
Languages : en
Pages : 307
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Book Description
This edition of Advances in Neurobiology brings together experts in the emerging field of Systems Neuroscience to present an overview of this area of research. Topics covered include: how different neural circuits analyze sensory information, form perceptions of the external world, make decisions, and execute movements; how nerve cells behave when connected together to form neural networks; the relationship between molecular and cellular approaches to understanding brain structure and function; the study of high-level mental functions; and studying brain pathologies and diseases with Systems Neuroscience. A hierarchy of biological complexity arises from the genome, transcriptome, proteome, organelles, cells, synapses, circuits, brain regions, the whole brain, and behaviour. The best way to study the brain, the most complex organ in the body composed of 100 billion cells with trillions of interconnections, is with a Systems Biology approach. Systems biology is an inter-disciplinary field that focuses on complex interactions within biological systems to reveal 'emergent properties' - properties of cells and groups of cells functioning as a system whose actual and theoretical description is only possible using Systems Biology techniques.
