Autism Spectrum Disorders: Developmental Trajectories, Neurobiological Basis, Treatment Update,Volume 2

Autism Spectrum Disorders: Developmental Trajectories, Neurobiological Basis, Treatment Update,Volume 2 PDF Author: Roberto Canitano
Publisher: Frontiers Media SA
ISBN: 2889638693
Category :
Languages : en
Pages : 191

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Autism Spectrum Disorders: Developmental Trajectories, Neurobiological Basis, Treatment Update,Volume 2

Autism Spectrum Disorders: Developmental Trajectories, Neurobiological Basis, Treatment Update,Volume 2 PDF Author: Roberto Canitano
Publisher: Frontiers Media SA
ISBN: 2889638693
Category :
Languages : en
Pages : 191

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Book Description


Autism Spectrum Disorders: Developmental Trajectories, Neurobiological Basis, Treatment Update

Autism Spectrum Disorders: Developmental Trajectories, Neurobiological Basis, Treatment Update PDF Author: Roberto Canitano
Publisher: Frontiers Media SA
ISBN: 2889452662
Category :
Languages : en
Pages : 175

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Book Description
This Research Topic has the aim to fill the gap of the many unresolved scientific issues on Autism Spectrum Disorders (ASD) that are still in need of investigation, Targeted treatments based on the understanding of the underlying pathogenic mechanisms of disease are still lacking. Further research is awaited and should be obtained through a significant effort on experimental treatment trials and neuroscience research. This Topic is divided in two main sections, one covering clinical issues and another on basic neurosciences of Autism Spectrum Disorders. A more detailed description of the contents of the articles is provided in the editorial at the beginning of the issue.

Autism

Autism PDF Author: Gregory R. Bock
Publisher: John Wiley & Sons
ISBN: 0470869372
Category : Science
Languages : en
Pages : 320

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Book Description
This book draws together contributions from some of the leading investigators in the field of autism to consider specific problem areas in current research. Each contributor brings expertise from a different field, providing a balanced view of the whole spectrum of study of this disorder. It covers four main areas: Twin and family studies indicate that the heritability of the underlying liability to autism exceeds 90% and point to a multifactorial causation, involving a relatively small number of susceptibility genes. The book discusses this issue in detail, along with the problem of why some additional symptoms are associated with autism while others are not. New techniques are available for examining the neurobiology of autism. The book contains results from imaging studies showing the contributions of different brain regions to autism. It includes neuropathological data and examines the neuropharmacology of autism. There is considerable discussion concerning the fundamental psychological deficit in children with autism. There is good evidence that "Theory of Mind" deficits are associated with autism and this issue is discussed in the book, as are other competing possibilities. The most important practical question facing medical and psychological practitioners is how to help children with autism. The evidence relating to possible psychological or psychiatric interventions for rehabilitation of children with autism is examined in detail. Drug treatments have generally been disappointing in this field and there is one chapter devoted specifically to this problem. The book focusses ultimately on intervention studies and so is of practical relevance to people interested in helping autistic children. In addition, it provides a very convenient summary of the principal controversies which currently exist in research on autism.

Neurobiology, diagnosis and treatment in autism

Neurobiology, diagnosis and treatment in autism PDF Author:
Publisher: John Libbey Eurotext
ISBN: 2742011854
Category :
Languages : en
Pages :

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Book Description
Autism is an extremely complex neurodevelopmental disorder that is expressed in a spectrum of phenotypes and is characterized by impaired reciprocal social communication and stereotyped patterns of interests and activities. Its aetiopathogenesis remains poorly understood. This book is an exhaustive synthesis discussing various aspects: - A focus on the neurobiology of autism: the candidate genes implicate an involvement of numerous brain regions and a concomitant malfunctioning of neurotransmitter, immunologic, and other mechanisms. - The most incisive rehabilitation models in their original formulation and the results achieved with the same or similar protocols in Italian centres (understanding, educating, language therapy, social skill training…) - The psychopharmacologic options for the condition of autism per se and for its associated, very frequent, comorbidities. It suggests a potential influence on professional practice and enables an up-to-date approach to effective diagnosis and treatment.

New treatment perspectives in autism spectrum disorders

New treatment perspectives in autism spectrum disorders PDF Author: Roberto Canitano
Publisher: Frontiers Media SA
ISBN: 2889195309
Category : Autism
Languages : en
Pages : 162

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Book Description
Developing novel and more effective treatments that improve quality of life for individuals with autism spectrum disorders is urgently needed. To date a wide range of behavioral interventions have been shown to be safe and effective for improving language and cognition and adaptive behavior in children and adolescents with ASD. However many people with ASD can receive additional benefit from targeted pharmacological interventions. One of the major drawback in setting up therapeutics intervention is the remarkable individual differences found across individuals with ASD. As a matter of fact the medications that are currently available address only symptoms associated with ASD and not the core domains of social and communication dysfunction. The pathogenesis paradigm shift of ASD towards synaptic abnormalities moved the research to pathway to disease that involve multiple systems and that are becoming the forefront of ASD treatment and are pointing toward the development of new targeted treatments. Some new therapeutics have been tested and others are being studied. In this context single gene disorders frequently associated with ASD such as Rett Syndrome, Fragile X and Tuberous Sclerosis have been of significant aid as neurobiology of these disorders is more clear and has a potential to shed light on the altered signaling in ASD. However much research is needed to further understand the basic mechanisms of disease and the relationship to idiopathic ASD. Clinical trials in children are underway with agents directed to core symptoms and to the associated disorders in the search of new therapeutics and progress are expected with possible new option for therapeutics in ASD in the upcoming future. Children and Adolescents with ASD and their families can provide important information about their experience with new treatments and this should be a priority for future research. In addition, research performed on genetic mouse models of ASD will keep on providing useful information on the molecular pathways dysrupted in the disease, thus contributing to identify novel drug targets.

Autism Spectrum Disorders

Autism Spectrum Disorders PDF Author: Dianne Zager
Publisher: Routledge
ISBN: 1135623856
Category : Education
Languages : en
Pages : 595

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Book Description
The field of autism has been growing at an unprecedented rate in recent years. In addition to an actual rise in the number of classic DSM-IV cases, broadened diagnostic criteria have uncovered a wider range of autistic behaviors and ability levels. The third edition of this well-known text continues the mission of its predecessors--to present a comprehensive, readable, up-to-date overview of the field of autism, one that links research, theory, and practice in ways that are accessible to both practitioners and parents. Key features include: *Expanded Coverage--To accommodate the recent explosion of research, the book has been expanded from 11 to 14 chapters that examine the impact of autism on the individual and the family from infancy through adulthood. *Expertise--Internationally recognized experts offer cutting-edge treatment and educational information on topics such as early diagnosis, medical treatment, assessment, educational methods, language development, behavior regulation, and family support. *Neurobiological Research--Comprehensive medical research and treatment chapters provide an understandable overview of neurobiological research and current treatments including when and how medication can be employed as part of a treatment plan. *Focus on Early Years--Old sections I and III have been combined and a new 3-chapter section on early identification and intervention added. *Focus on Parents and Families--In addition to a chapter on the evolving role of families, a new chapter addresses family needs during the preschool years. *Integration of Assessment and Intervention--The chapters on assessment and intervention have been reorganized and more closely integrated in keeping with current thinking about their inter-relatedness. *Future Directions--Two chapters discuss emerging directions in this exploding field and how to make informed decisions among a variety of approaches. This book is appropriate for anyone--students, practitioners, or parents--who must provide care for an autistic child.

Handbook of Life Course Health Development

Handbook of Life Course Health Development PDF Author: Neal Halfon
Publisher: Springer
ISBN: 3319471430
Category : Medical
Languages : en
Pages : 667

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Book Description
This book is open access under a CC BY 4.0 license. ​This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important less-studied conditions (hearing, kidney health), and large-scale issues (nutrition, adversity) from a lifespan viewpoint. In addition, chapters address methodological approaches and challenges by analyzing existing measures, studies, and surveys. The book concludes with the editors’ research agenda that proposes priorities for future LCHD research and its application to health care practice and health policy. Topics featured in the Handbook include: The prenatal period and its effect on child obesity and metabolic outcomes. Pregnancy complications and their effect on women’s cardiovascular health. A multi-level approach for obesity prevention in children. Application of the LCHD framework to autism spectrum disorder. Socioeconomic disadvantage and its influence on health development across the lifespan. The importance of nutrition to optimal health development across the lifespan. The Handbook of Life Course Health Development is a must-have resource for researchers, clinicians/professionals, and graduate students in developmental psychology/science; maternal and child health; social work; health economics; educational policy and politics; and medical law as well as many interrelated subdisciplines in psychology, medicine, public health, mental health, education, social welfare, economics, sociology, and law.

Autism Spectrum Disorder within Neurodevelopmental Disorders: Catching Heterogeneity, Specificity and Comorbidity in Clinical Phenotypes and Neurobiological Bases

Autism Spectrum Disorder within Neurodevelopmental Disorders: Catching Heterogeneity, Specificity and Comorbidity in Clinical Phenotypes and Neurobiological Bases PDF Author: Eugenia Conti
Publisher: Frontiers Media SA
ISBN: 2889769526
Category : Science
Languages : en
Pages : 220

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Book Description


Neurodevelopmental Disorders

Neurodevelopmental Disorders PDF Author: Jo Van Herwegen
Publisher: Psychology Press
ISBN: 131756359X
Category : Psychology
Languages : en
Pages : 379

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Book Description
Interest in the field of neurodevelopmental disorders has grown exponentially in recent years across a range of disciplines, including psychology, psychiatry, education and neuroscience. The research itself has become more sophisticated, using multidisciplinary methods to probe interdisciplinary questions. Neurodevelopmental Disorders: Research Challenges and Solutions provides a thorough overview of the key issues involved in researching neurodevelopmental disorders. The volume includes 14 chapters, arranged over three sections. Chapters in the first section address general research challenges for the study of neurodevelopmental disorders. The second section draws upon specific disorders (such as Williams syndrome, Autism Spectrum Disorders, Down Syndrome, Fragile X Syndrome, ADHD, and Language Disorders) to consider the syndrome-specific issues or challenges that may be crucial to advancing our understanding of aspects of cognition and behavior associated with them. The final section considers how research evidence may be translated into practice to begin making an impact upon the lives of individuals who have neurodevelopmental disorders and their families. Each chapter in the book also includes ‘practical tips’ for either conducting research with individuals who have neurodevelopmental disorders or considering wider practical issues. The book will be indispensable reading for advanced students, researchers, and practitioners in the fields of developmental psychology, developmental psychopathology, special needs education, neuropsychology, and neurodevelopmental disorders.

The Neurochemical Basis of Autism

The Neurochemical Basis of Autism PDF Author: Gene J. Blatt
Publisher: Springer Science & Business Media
ISBN: 144191272X
Category : Medical
Languages : en
Pages : 295

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Book Description
A perceived rise in autism worldwide has led to a dramatic increase in autism research. This is a uniquely interdisciplinary text that presents the latest findings regarding the physiological, neuropathological, neurochemical and clinical elements of autism.