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Author: Tariq Aftab
Publisher: Springer Science & Business Media
ISBN: 3642410278
Category : Science
Languages : en
Pages : 292
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Book Description
Artemisinin, a sesquiterpene lactone originally extracted from the medicinal plant Artemisia annua L., is an effective antimalarial agent, particularly for multi-drug resistant and cerebral malaria. However, the concentration of artemisinin in the plant is very low. Because the chemical synthesis of artemisinin is complicated and not economically feasible in view of the poor yield of the drug, the intact plant remains the only viable source of artemisinin production. Therefore, it is necessary to increase the concentration of artemisinin in A. annua to reduce the cost of artemisinin based antimalarial drugs. Plant scientists have focused their efforts on A. annua for a higher artemisinin crop yield. With the present volume, we are bringing together the research which is being done on this plant throughout the world and future possibilities for scientists and researchers who want to work on it.
Author: Tariq Aftab
Publisher: Springer Science & Business Media
ISBN: 3642410278
Category : Science
Languages : en
Pages : 292
Get Book
Book Description
Artemisinin, a sesquiterpene lactone originally extracted from the medicinal plant Artemisia annua L., is an effective antimalarial agent, particularly for multi-drug resistant and cerebral malaria. However, the concentration of artemisinin in the plant is very low. Because the chemical synthesis of artemisinin is complicated and not economically feasible in view of the poor yield of the drug, the intact plant remains the only viable source of artemisinin production. Therefore, it is necessary to increase the concentration of artemisinin in A. annua to reduce the cost of artemisinin based antimalarial drugs. Plant scientists have focused their efforts on A. annua for a higher artemisinin crop yield. With the present volume, we are bringing together the research which is being done on this plant throughout the world and future possibilities for scientists and researchers who want to work on it.
Author: Taylor & Francis Group
Publisher: CRC Press
ISBN: 9781032095899
Category :
Languages : en
Pages : 340
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Book Description
Artemisia annua is a well-known medicinal plant that has been utilized for a number of purposes, including malaria, for centuries. This is the first comprehensive book to cover the importance of Artemisia annua in the global health crisis and in the treatment against diseases. A component and extract, artemisinin, is the source of other derivatives which are also suitable for pharmaceutical use. The present demand for artemisinin far outpaces its supply. Researchers are working globally towards improving artemisinin content in the plant by various means. Artemisia annua: Prospects, Applications and Therapeutic Uses highlights the different approaches, including 'omics', that are being used in current research on this immensely important medicinal plant. Providing comprehensive coverage of the agricultural and pharmaceutical uses of this plant, Artemisia annua will be essential reading for botanists, plant scientists, herbalists, pharmacognosists, pharmacologists and natural product chemists.
Author: Tariq Aftab
Publisher: CRC Press
ISBN: 1351802852
Category : Health & Fitness
Languages : en
Pages : 431
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Book Description
Artemisia annua is a well-known medicinal plant that has been utilized for a number of purposes, including malaria, for centuries. This is the first comprehensive book to cover the importance of Artemisia annua in the global health crisis and in the treatment against diseases. A component and extract, artemisinin, is the source of other derivatives which are also suitable for pharmaceutical use. The present demand for artemisinin far outpaces its supply. Researchers are working globally towards improving artemisinin content in the plant by various means. Artemisia annua: Prospects, Applications and Therapeutic Uses highlights the different approaches, including ‘omics', that are being used in current research on this immensely important medicinal plant. Providing comprehensive coverage of the agricultural and pharmaceutical uses of this plant, Artemisia annua will be essential reading for botanists, plant scientists, herbalists, pharmacognosists, pharmacologists and natural product chemists.
Author: Colin W. Wright
Publisher: CRC Press
ISBN: 0203303067
Category : Science
Languages : en
Pages : 296
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Book Description
A comprehensive overview of this genus, Artemisia examines all aspects of the herbs uses and applications, its mode of action and clinical importance. Following a comprehensive introduction to the genus, the book discusses the botanical, phytochemical and biological aspects of a number of important species of Artemisis. Considering that the discove
Author: Mahendra Rai
Publisher: Academic Press
ISBN: 0124017088
Category : Medical
Languages : en
Pages : 296
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Book Description
Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components offers scientists a single source aimed at fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses and fungi using natural products. This essential reference discusses herbal extracts and essential oils used or under investigation to treat MDR infections, as well as those containing antimicrobial activity that could be of potential interest in future studies against MDR microorganisms. The need to combat multidrug-resistant microorganisms is an urgent one and this book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components and more to aid researchers in effective antimicrobial drug discovery Addresses the need to develop safe and effective approaches to coping with resistance to all classes of antimicrobial drugs Provides readers with current evidence-based content aimed at using herbal extracts and essential oils in antimicrobial drug development Includes chapters devoted to the activity of herbal products against herpes, AIDS, tuberculosis, drug-resistant cancer cells and more
Author: Youyou Tu
Publisher: Academic Press
ISBN: 0128116560
Category : Medical
Languages : en
Pages : 468
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Book Description
From Artemisia annua L. to Artemisinins: The Discovery and Development of Artemisinins and Antimalarial Agents is the first book that systematically introduces the origin and development of artemisinine and artemisinine-based drugs. It includes four distinct sections, including Artemisia annua L., Artemisinin, Dihydroartemisinin, and other artemisinin derivatives. Tu Youyou, the chief inventor of artemisinin, together with other members from the research team, have written a book that will be a valuable reference work for both researchers involved in the medical industry and scholars who are interested in undertaking innovative research. Presents a full view of artemisinin, not only its origin and development, but also chemical structure, chemical properties, extracting mode, derivatives, chromogenic reaction, general pharmacological, and toxicology. Provides many aspects of artemisinin-based drugs Incudes lots of experimental data, such as the X-ray crystallography result—the first application reported in China in determining the absolute molecular configuration utilizing the scattering effects of oxygen atoms by X-ray diffraction technique
Author: Merlin Willcox
Publisher: CRC Press
ISBN: 0203502329
Category : Health & Fitness
Languages : en
Pages : 464
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Book Description
Malaria is an increasing worldwide threat, with more than three hundred million infections and one million deaths every year. The worlds poorest are the worst affected, and many treat themselves with traditional herbal medicines. These are often more available and affordable, and sometimes are perceived as more effective than conventional antimala
Author: Rao Yi
Publisher: World Scientific
ISBN: 9813109912
Category : Medical
Languages : en
Pages : 224
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Book Description
Nobel laureate Tu Youyou won the 2015 prize for Medicine/Physiology for the discovery of artemisinin, a drug therapy for malaria that has saved millions across the globe. This book traces the path of discovery beginning with Chairman Mao's 1964 instruction to Chinese researchers to find a cure for malaria, a disease that plagued the military and civilians alike in endemic regions. It chronicles the years of painstaking research to find effective anti-malarial drugs, and how an entry in a collection of traditional Chinese medicine prescriptions gave Tu Youyou the clue which led her to successfully extract artemisinin from the plant, Artemisia annua. Gathering together information from a variety of sources including first-hand accounts, this book describes the contributions of the many organisations, scientists, doctors and countless others who played a part in the process of discovery and clinical testing. It also provides insights into the challenges of carrying out such an extensive research project with limited resources during the upheavals of the Cultural Revolution. An inspirational read for young scientists. Includes the translation of Professor Tu Youyou's 2015 Nobel Lecture.
Author: Manuela Simioni
Publisher:
ISBN: 9783319500096
Category : Ethnobotany
Languages : en
Pages :
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Book Description
"The Caucasus MRW (online and print) Volume will cover this European Macroregion. The content will focus on the ethnobotany of wild plants in this Macroregion and it will be first developed as an online site and, later, when all of the planned topics have been covered for this specific volume, printed in a hard copy version. The online site will remain live and be available for updates (with new monographs [if not covered initially due to lack of research]). The content will be divided into sections covering countries (or groups of countries), based on plant diversity and not necessarily political or national boundaries. The Caucasus volume will have an Introduction (4,000-6,000 words); 50 200 plant monographs (10 to maximum 50 monographs per country) with each monograph having a length of ~1,500 words (with references), plus 2-4 photographs. To further define the content, the plant monographs will be divided into five major categories (food; medicine/cosmetic; veterinary; handicraft plants; and ritual/folkloric uses) and include notes. The number of the monographs in every category will be negotiated depending on the advances of the ethnobotanical research in each specific country, or group of countries. The main criteria for the inclusion of a given plant will be its cultural salience within a given country (assessed by the Volume Editor). References will be given at the end of the Introduction and each monograph..."--Publisher's website.
Author:
Publisher:
ISBN: 9789241594431
Category : Antimalarials
Languages : en
Pages : 49
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Book Description
