Approaches to Design and Synthesis of Antiparasitic Drugs PDF Download
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Author: N. Anand
Publisher: Elsevier
ISBN: 9780080527529
Category : Medical
Languages : en
Pages : 510
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Book Description
This book presents a comprehensive and up to date account of the chemotherapy of parasitic diseases, both human and veterinary. The book starts with an overview of parasitic diseases. The body of the book is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. Both parts start with chapters highlighting the 'biochemical targets' available for chemotherapeutic interference. Individual chapters deal with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and methods of synthesis and their status both in clinical and veterinary practice. The book will be useful to a wide spectrum of readers: students embarking on a research career in parasitic chemotherapy, clinicians (and veterinarians) and clinical pharmacologists desiring detailed information about the drugs currently in use, and pharmaceutical technologists wanting to update their knowledge of the methods of manufacture.
Author: N. Anand
Publisher: Elsevier
ISBN: 9780080527529
Category : Medical
Languages : en
Pages : 510
Get Book
Book Description
This book presents a comprehensive and up to date account of the chemotherapy of parasitic diseases, both human and veterinary. The book starts with an overview of parasitic diseases. The body of the book is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. Both parts start with chapters highlighting the 'biochemical targets' available for chemotherapeutic interference. Individual chapters deal with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and methods of synthesis and their status both in clinical and veterinary practice. The book will be useful to a wide spectrum of readers: students embarking on a research career in parasitic chemotherapy, clinicians (and veterinarians) and clinical pharmacologists desiring detailed information about the drugs currently in use, and pharmaceutical technologists wanting to update their knowledge of the methods of manufacture.
Author:
Publisher: Academic Press
ISBN: 0080583482
Category : Medical
Languages : en
Pages : 364
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Book Description
Annual Reports in Medicinal Chemistry
Author: Ruben Vardanyan
Publisher: Academic Press
ISBN: 0124115241
Category : Science
Languages : en
Pages : 868
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Book Description
Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation
Author: Rajaram S. Mane
Publisher: Springer Nature
ISBN: 9819916356
Category : Science
Languages : en
Pages : 333
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Book Description
This book highlights recent advances in variety of nanomaterials classes including metal chalcogenides, metal oxides/hydroxides, polymer, metal-organic frameworks, and hybrid nanostructures, with a focus on their properties, synthesis methods, and key applications. It also offers detailed coverage on the toxicity aspects with possible solution. Additionally, it provides complete and comprehensive information on surface modification strategies of nanoparticles to achieve desired outcomes. This book discusses potential applications and major challenges of using these nanomaterials in the fields of biomedical sciences, agricultural industry, bioenergy, biofuel production, and environmental remediation, etc. Overall, this book provides crucial background in nanobiotechnology that compliments the understanding of experimental design for the production of more customized nanomaterials to avail desirable benefits.
Author: Venkatesan Jayaprakash
Publisher: CRC Press
ISBN: 1351011634
Category : Medical
Languages : en
Pages : 461
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Book Description
Medicinal Chemistry of Neglected and Tropical Diseases: Advances in the Design and Synthesis of Antimicrobial Agents consolidates and describes modern drug discovery and development approaches currently employed to identify effective chemotherapeutic agents for the treatment of Neglected Tropical Diseases (NTDs) from a medicinal chemistry perspective. Chapters are designed to cater to the needs of medicinal chemists who work with chemotherapeutic developments for NTDs, as well as serve as a guide to budding medicinal chemists who wish to work in this area. It will introduce rational drug design approaches adopted in designing chemotherapeutics and validated targets available for the purpose.
Author: Patricia Covarrubia
Publisher: Taylor & Francis
ISBN: 1000791041
Category : Law
Languages : en
Pages : 172
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Book Description
Since the Intangible Heritage Convention was adopted by UNESCO in 2003, intangible cultural heritage has increasingly been an important subject of debate in international forums. As more countries implement the Intangible Heritage Convention, national policymakers and communities of practice have been exploring the use of intellectual property protection to achieve intangible cultural heritage safeguarding outcomes. This book examines diverse cultural heritage case studies from Indigenous communities and local communities in developing and industrialised countries to offer an interdisciplinary examination of topics at the intersection between heritage and property which present cross-border challenges. Analysing a range of case studies which provide examples of traditional knowledge, traditional cultural expressions, and genetic resources by a mixture of practitioners and scholars from different fields, the book addresses guidelines and legislation as well as recent developments about shared heritage to identify a progressive trend that improves the understanding of intangible cultural heritage. Considering all forms of intellectual property, including patents, copyright, design rights, trade marks, geographical indications, and sui generis rights, the book explores problems and challenges for intangible cultural heritage in crossborder situations, as well as highlighting positive relationships and collaborations among communities across geographical boundaries. Transboundary Heritage and Intellectual Property Law: Safeguarding Intangible Cultural Heritage will be an important resource for practitioners, scholars, and students engaged in studying intangible cultural heritage, intellectual property law, heritage studies, and anthropology.
Author: Clarissa Campos Barbosa de Castro
Publisher: Elsevier Inc. Chapters
ISBN: 0128066792
Category : Medical
Languages : en
Pages : 296
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Book Description
Schistosomiasis is a neglected tropical disease that affects more than 240 million individuals throughout the world. Praziquantel and oxamniquine are the only drugs available for the control of schistosomiasis. Our dependence on just two drugs and concerns about tolerance and/or resistant schistosome strains emphasize the need for developing new schistosomicidal drugs. This chapter summarizes recent reports about schistosomicidal activity of natural products against Schistosoma species. The in vitro and in vivo effects of a number of crude plant extracts, essential oils, and several secondary metabolites (including alkaloids, flavonoids, and lignans) on schistosoma are summarized and discussed. Particular emphasis is placed on in vivo studies and on works describing the direct in vitro effects of natural products on the parasite (schistosomula and adult stages). Some interesting results with promising samples have already been obtained, but more research is required to discover an ideal natural schistosomicidal lead candidate.
Author: H. van der Goot
Publisher: Elsevier
ISBN: 9780080543246
Category : Science
Languages : en
Pages : 246
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Book Description
This volume of Pharmacochemistry Library comprises the text of invited lectures presented at the 11th Noordwijkerhout-Camerino Symposium Trends in Drug Research, held in Noordwijkerhout, The Netherlands, from 11-15 May 1997. In the programme attention has been given to the generation of new biological target systems and the generation of new lead molecules, with presentations on e.g. combinatorial chemistry, compound libraries, database search, high throughput screening and molecular biology. Other topics discussed were the perspectives for new medicines for the gastro-intestinal tract, the major developments in the search for effective anti-HIV drugs and new aspects in synthetic approaches. In a special session three topics which currently draw much attention were discussed: How to deal with the major problem of resistance against antimirobial agents? Can the apoptosis mechanism be used as a drug target? Is the newly observed phenomenon of inverse agonism a general principle and has it consequences for drug development (and use?)
Author: Sriram D .
Publisher: Pearson Education India
ISBN: 9788131731444
Category : Pharmaceutical chemistry
Languages : en
Pages : 716
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Book Description
The second edition of Medicinal Chemistry is based on the core module of pharmacy syllabi of various technical universities, and targets undergraduate B. Pharma students across India. The current edition has been designed by authors based on the opinion of the experts to include the latest developments in the field of medicinal chemistry, detailed synthesis mechanism of the drugs and their mode of action inside the body.
Author: H. van der Goot
Publisher: Elsevier
ISBN: 9780080543239
Category : Medical
Languages : en
Pages : 272
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Book Description
The tradition of setting new trends in medicinal chemistry continued at the 13th Symposium where topics included chemical and biological diversity, new paradigms in drug action, and new insights in receptor mechanisms. Other topics of great interest discussed, and included in these proceedings, are the discoveries in green chemistry, the interface between organic synthesis and biosynthesis, the growing problem of resistant micro-organisms and the possibilities to identify new, and better, antibiotics. And finally, in recent developments, the discovery of small molecules with insulin sensitizing properties.
