An Introduction to Molecular Medicine and Gene Therapy PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download An Introduction to Molecular Medicine and Gene Therapy PDF full book. Access full book title An Introduction to Molecular Medicine and Gene Therapy by Thomas F. Kresina. Download full books in PDF and EPUB format.
Author: Thomas F. Kresina
Publisher: John Wiley & Sons
ISBN: 0471461040
Category : Science
Languages : en
Pages : 408
Get Book
Book Description
An Introduction to Molecular Medicine and Gene Therapy Edited by Thomas F. Kresina, Ph.D. Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections - an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine and Gene Therapy: * Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations * Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases * Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter * Contains appendices on commercial implications and a review of the history of gene therapy This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine.
Author: Thomas F. Kresina
Publisher: John Wiley & Sons
ISBN: 0471461040
Category : Science
Languages : en
Pages : 408
Get Book
Book Description
An Introduction to Molecular Medicine and Gene Therapy Edited by Thomas F. Kresina, Ph.D. Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections - an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine and Gene Therapy: * Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations * Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases * Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter * Contains appendices on commercial implications and a review of the history of gene therapy This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine.
Author: Thomas F. Kresina
Publisher:
ISBN: 9781891786020
Category :
Languages : en
Pages : 300
Get Book
Book Description
Author: Jens Kurreck
Publisher: John Wiley & Sons
ISBN: 3527331891
Category : Science
Languages : en
Pages : 419
Get Book
Book Description
Easy to read, yet comprehensive, this is the perfect introduction into the molecular basis of disease and the novel treatment options that have become available. The authors, Jens Kurreck and Cy Stein, have both long-standing teaching experience on the subject, one from a biologist's angle, the other with a medical background. Together, they have produced a modern textbook for courses in Molecular Medicine that incorporates modules from immunology to signaling, from virology to gene therapy, and the latest development in personalized medicine.
Author: Dennis W. Ross
Publisher: Springer Science & Business Media
ISBN: 147574076X
Category : Medical
Languages : en
Pages : 174
Get Book
Book Description
How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and find entry to the more specialized publications. The first chapters present the basic concepts of the human genome and gene regulation. Subsequent chapters consider how today's new approach can be applied in areas such as forensic medicine, transplantation medicine, drug manufacture and genetic engineering. For example, a major section on cancer explores the diagnosis of leukemia and lymphoma through the detection of gene rearrangement and oncongeny mutation. One feature that will especially interest pathologists, pediatricians and residents is the discussion of diagnostic tests that are used in current practice.
Author: Pamela Greenwell
Publisher: John Wiley & Sons
ISBN: 9780470725146
Category : Science
Languages : en
Pages : 264
Get Book
Book Description
"This book should be useful to lecturers who teach senior undergraduates, graduate students, and students in the biomedical sciences in general. More globally, Greenwell and McCulley's book should encourage academicians of any stripe who for some time have been honing their lectures in a niche subject area to turn their courses into textbooks." –Biochemistry and Molecular Biology Education Molecular therapeutics refers to the developments in molecular biology that are focused on treating disease with new molecular-based drugs. By taking advantage of recent advances and increased understanding in the field of human genetics, this book provides essential background knowledge and key literature on a broad range of novel approaches and disciplines. These include making recombinant proteins, xenotransplantation gene therapy and therapeutic cloning. Molecular Therapeutics: 21st Century Medicine describes the techniques - including their associated benefits, problems, pitfalls - and discusses their applicability with respect to treating microbial, inherited, multifactoral and acquired diseases. The book also pays specific attention to the ethical issues associated with this new field. Cutting-edge topics and clinically relevant materials engage and maintain student interest Self-assessment questions are included throughout the book Features an additional web site, with a web forum, regular updates and PowerPoint slides of figures from the book Molecular Therapeutics: 21st Century Medicine is a comprehensive, accessible and engaging guide to the rapidly developing field of molecular therapeutics. It is essential reading for all students in this area of research and also of interest for health professionals involved in these novel therapies.
Author: R. J. Trent
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 256
Get Book
Book Description
The second edition of this popular book provides an overview of the impact which recombinant DNA (rDNA) technology is having on medical practice. Called molecular medicine, this rapidly expanding area has an increasing role to play in medicine and this book addresses the importance of this challenging area. This new edition has been fully updated with the developments of the last few years. Key genes identified include BRCA1 (breast cancer) OB (obese) and those involved in DNA repair. In addition the author covers the increase in gene therapy trials and the shifting of emphasis from genetic disorders to the cancers and HIV infection.
Author: Barry Mendelow
Publisher: NYU Press
ISBN: 1868147134
Category : Science
Languages : en
Pages : 531
Get Book
Book Description
This book is suitable for undergraduate medical students, as part of their basic sciences training, but is also relevant to interested under- and postgraduate science and engineering students. There is a special focus on the application of molecular medicine in Africa and in developing countries elsewhere.
Author: Mauro Giacca
Publisher: Springer Science & Business Media
ISBN: 8847016436
Category : Medical
Languages : en
Pages : 303
Get Book
Book Description
I entered the gene therapy field in the mid-1990s, being fascinated by the immense potential of genes as drugs for the treatment of human disease. Since then, I have experienced the ups and downs of this discipline, and tried to contribute with my work and that of my laboratory to the development of innovative approaches to the treatment of cardiovascular disorders. During these years, I have had several opp- tunities to speak on gene therapy at lectures and academic lessons, and have often noticed that the field is very attractive to scientists of all disciplines. However, as yet no comprehensive book on the subject has been published. Indeed, most books in the field are either a collection of gene transfer laboratory protocols or deal with the subject in a rather superficial manner. Hence the idea to write a gene therapy textbook that is broad and comprehensive, but at the same time provides sufficient molecular and clinical detail to be of interest to students, professors, and specialists in the various disciplines that contribute to gene therapy. I have tried to keep the language plain and, whenever possible, non-technical. Since the book is intended to be a textbook in the field of gene therapy in both the basic science and clinical areas, whenever technical descriptions are required, they are provided.
Author: John R. Bradley
Publisher: Wiley-Blackwell
ISBN: 9780632058396
Category : Medical
Languages : en
Pages : 0
Get Book
Book Description
Lecture Notes on Molecular Medicine provides a concise and straightforward introduction to molecular biology, explaining how it is used to understand and treat human disease. This new edition has been written in response to exciting changes in this fast-moving field. Fully updated, it explains the human genome project and how the sequence will change medicine. It also covers many new methods that have been introduced since the first edition was published. Beginning with first principles, the book is a useful primer for any science student new to molecular biology and genetics. It is also an invaluable resource for medical students and practicing doctors who need an understanding of how advances in molecular biology have impacted clinical medicine, especially in the fields of gene therapy and screening. For ease of use Lecture Notes on Molecular Medicine is divided into four sections: Basic Principles: describing the fundamentals of DNA structure and function that underpin molecular biology Biomolecular Tools: covering the manipulation of DNA and RNA and molecular techniques. Understanding Genetics: covering the basic principles of inheritance, biodiversity, gene mapping and expression and gene therapy. Molecular Medicine in Practice: discussing the profound effect which molecular biology has had on medical practice at all levels. This chapter has been greatly expanded in this new edition to cover all the latest developments in the field. A concise introduction to the basic principles & applications of molecular medicine. Explains complicated science in simple terms with clear diagrams. Integrates basic and clinical science by emphasising application to clinical medicine. Expanded chapter examining molecular medicine in clinical practice.
Author: William R. Clark
Publisher: Oxford University Press
ISBN: 0195130847
Category : Medical
Languages : en
Pages : 256
Get Book
Book Description
This popular exploration of gene therapy presents the underlying molecular biology in readily accessible form, and lays out the early efforts and future prospects for gene therapy to revolutionize the treatment of human genetic diseases.
