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Author: Emmanuel Jouanneau
Publisher: Springer Nature
ISBN: 3030411761
Category : Medical
Languages : en
Pages : 231
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Book Description
This volume focuses on adult craniopharyngiomas, offering various perspectives. The first part of the book provides an up-to-date overview of the pathogenesis and management of adult craniopharyngiomas, helping readers understand the pathogenesis and molecular pathways. It highlights the importance of animal models for addressing molecular keys and for developing targeted therapies. The second part deals with clinical management, detailing the latest results in the era of endoscopic surgery, including the major contribution of the extended nasal endoscopic approaches for suprasellar and retrochiasmatic tumors. The book also discusses the key aspects of these tumors and how to manage them. The last part of the book addresses the future therapies and recurrences after surgery and radiotherapy. This volume is of interest to neurosurgeons, endocrinologists, paediatricians, radiologists and oncologists.
Author: Emmanuel Jouanneau
Publisher: Springer Nature
ISBN: 3030411761
Category : Medical
Languages : en
Pages : 231
Get Book
Book Description
This volume focuses on adult craniopharyngiomas, offering various perspectives. The first part of the book provides an up-to-date overview of the pathogenesis and management of adult craniopharyngiomas, helping readers understand the pathogenesis and molecular pathways. It highlights the importance of animal models for addressing molecular keys and for developing targeted therapies. The second part deals with clinical management, detailing the latest results in the era of endoscopic surgery, including the major contribution of the extended nasal endoscopic approaches for suprasellar and retrochiasmatic tumors. The book also discusses the key aspects of these tumors and how to manage them. The last part of the book addresses the future therapies and recurrences after surgery and radiotherapy. This volume is of interest to neurosurgeons, endocrinologists, paediatricians, radiologists and oncologists.
Author: Emmanuel Jouanneau
Publisher: Springer
ISBN: 9783030411756
Category : Medical
Languages : en
Pages : 231
Get Book
Book Description
This volume focuses on adult craniopharyngiomas, offering various perspectives. The first part of the book provides an up-to-date overview of the pathogenesis and management of adult craniopharyngiomas, helping readers understand the pathogenesis and molecular pathways. It highlights the importance of animal models for addressing molecular keys and for developing targeted therapies. The second part deals with clinical management, detailing the latest results in the era of endoscopic surgery, including the major contribution of the extended nasal endoscopic approaches for suprasellar and retrochiasmatic tumors. The book also discusses the key aspects of these tumors and how to manage them. The last part of the book addresses the future therapies and recurrences after surgery and radiotherapy. This volume is of interest to neurosurgeons, endocrinologists, paediatricians, radiologists and oncologists.
Author: James J. Evans
Publisher: Academic Press
ISBN: 0124167233
Category : Medical
Languages : en
Pages : 612
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Book Description
Craniopharyngiomas: A Comprehensive Guide to Diagnosis, Treatment and Outcome is a comprehensive guide to the science, diagnosis and treatment of craniopharyngiomas, rare brain tumors that grow near the pituitary gland. Even though these tumors are generally benign, due to the location, prognosis was often bleak. This reference provides a resource for specialists requiring a comprehensive overview of this rare form of tumor, outlining new diagnostic, imaging and surgical techniques, including endoscopic endonasal cranial base surgery, which enable successful neurosurgical intervention. With a better prognosis, patients require multidisciplinary management from neurology, otolaryngology, radiation oncology, endocrinology, and neuropathology. The only comprehensive guide to the science, diagnosis and treatment of craniopharyngiomas Includes multidisciplinary management from neurology, otolaryngology, radiation oncology, endocrinology, and neuropathology Detailed coverage of the impacts of new diagnostic, imaging and neurosurgical techniques including endoscopic endonasal cranial base surgery
Author: Hermann L. Mueller
Publisher: Frontiers E-books
ISBN: 2889190617
Category :
Languages : en
Pages : 91
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Book Description
Craniopharyngiomas are benign, partly cystic embryogenic malformations of the sellar region, presumably derived from Rathke cleft epithelium. With an overall incidence of 0.5–2 new cases per million population per year, approximately 30-50% of all cases represent childhood craniopharyngioma. Typical manifestations at primary diagnosis are headache, visual impairment, polyuria/polydypsia, growth retardation, and weight gain. One of the biggest challenges in treating craniopharyngioma is identifying the best candidates for the radical versus the conservative approach. It appears there is a trend towards radiotherapy in centers with past prevalent surgical approaches, and towards more radical surgical treatment strategies in centers historically conservative-oriented. There are current prospective studies underway on a national and multinational level to adopt strategies tailored to risk factors for morbidity and QOL. Therapy of choice in patients with favorable tumor localization is total resection with the intention to maintain optical nerve and hypothalamic-pituitary functions. In patients with unfavorable tumor localization (hypothalamic tumor involvement), a limited resection followed by local irradiation is recommended. The overall survival rates are high (92%). Recurrences after complete resection and progressions of residual tumor after incomplete resection are anticipated subsequent events after primary surgery. In clinical practice, the timing of postoperative residual tumor irradiation is both unclear and inconsistently regarded. Some favor immediate postoperative irradiation in the event of life-impairing clinical conditions, proactively preventing tumor progression. On the other hand, some favor a wait-and-see procedure, delaying irradiation in order to reduce both its necessity and the negative consequences associated with radiation therapy. Inarguably, immediate postoperative irradiation significantly delays tumor progression. However, progression-contingent irradiation has proved effective, as overall survival is statistically unaffected by this wait-and-see strategy. Accordingly, the appropriate time point of irradiation after incomplete resection is currently under investigation in a randomized trial (KRANIOPHARYNGEOM 2007). Quality of life is substantially reduced in appr. 50% of long-term survivors due to sequelae, notably extreme obesity due to hypothalamic involvement. Due to the lack of satisfactory long-term treatment modalities for hypothalamic sequelae, further research on molecular characteristics of craniopharyngioma, pathophysiology of hypothalamic disorders, and pharmaceutical agents to treat hypothalamic obesity are warranted. Risk-adapted surgical strategies at initial diagnosis should aim at a maximal degree of resection, respecting the integrity of optical and hypothalamic structures in order to prevent severe sequelae and therein minimizing consequences that could negative impact patient QOL. Because initial hypothalamic tumor involvement has an apriori effect on the clinical course, childhood craniopharyngioma should be recognized as a chronic disease requiring constant monitoring of the consequences and medical resources for treatment in order to provide not only optimal QOL for patients, but also to garner additional information with the intent of minimizing what at present are severe consequences of both the disease and its treatment.
Author: Songtao Qi
Publisher: Bentham Science Publishers
ISBN: 1681085321
Category : Medical
Languages : en
Pages : 437
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Book Description
Craniopharyngiomas are a type of brain tumour in the suprasellar region with benign histological and cellular features. Clinical manifestations of craniopharyngiomas include decreased vision, hypopituitarism, hypothalamus dysfunction, fluid and electrolyte imbalance, glycometabolism, lipid metabolism and obesity. Craniopharyngiomas can show some characteristics of malignant tumours, such as invasion to the surrounding tissues, repetitious recurrence, and rapid growth. These characteristics cause considerable difficulty in patient treatment for neurosurgeons all over the world. This volume presents detailed information about craniopharyngioma anatomy, classification and treatment.
Author: Andrea Lania
Publisher: Springer
ISBN: 331922297X
Category : Medical
Languages : en
Pages : 153
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Book Description
This book provides up-to-date coverage of the most relevant topics in the diagnosis and management of craniopharyngiomas. After introductory discussion of natural history and clinical presentation, individual chapters are devoted to pathological and molecular aspects, use of diagnostic imaging techniques, the surgical approach to craniopharyngiomas, radiotherapy and radiosurgery, and associated endocrine disturbances. A particular feature of the book is the detailed attention devoted to the metabolic consequences of the disease and related treatments, including obesity and electrolyte disturbances, and to cognitive alterations. This book will be of value to oncologists, neurosurgeons, and endocrinologists by assisting in diagnostic workup, delivery of appropriate treatment, and management of the serious metabolic and endocrine consequences.
Author: Lia M. Halasz
Publisher: Springer Nature
ISBN: 3030645088
Category : Medical
Languages : en
Pages : 208
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Book Description
This book is a practical, up-to-date guide to the treatment of patients with brain and spinal tumors. Leading experts in the field explain treatment techniques in detail, highlighting key considerations in the use of external beam radiation therapy, intensity-modulated radiation therapy, particle therapy, radiosurgery, and stereotactic body radiation therapy. Specific recommendations are described for different tumor types, and helpful information provided on other important issues, such as the interaction of radiotherapy and systemic therapy and the avoidance of treatment complications. With the development of modern technology, highly conformal radiotherapy techniques have become more complicated, yet also more widely employed. This book will equip readers with the knowledge required to set up practices to deliver quality brain and spinal radiation therapy appropriate to each patient. It will be of benefit to radiation oncologists, clinical oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses as well as medical oncologists and surgical oncologists with an interest in radiotherapy.
Author: F. Allan Midyett
Publisher: Springer Nature
ISBN: 3030464474
Category : Medical
Languages : en
Pages : 374
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Book Description
This book is a comprehensive guide to skull base imaging. Skull base is often a “no man’s land” that requires treatment using a team approach between neurosurgeons, head and neck surgeons, vascular interventionalists, radiotherapists, chemotherapists, and other professionals. Imaging of the skull base can be challenging because of its intricate anatomy and the broad breadth of presenting pathology. Although considerably complex, the anatomy is comparatively constant, while presenting pathologic entities may be encountered at myriad stages. Many of the pathologic processes that involve the skull base are rare, causing the average clinician to require help with their diagnosis and treatment. But, before any treatment can begin, these patients must come to imaging and receive the best test to establish the correct diagnosis and make important decisions regarding management and treatment. This book provides a guide to neuoradiologists performing that imaging and as a reference for related physicians and surgeons. The book is divided into nine sections: Pituitary Region, Cerebellopontine Angle, Anterior Cranial Fossa, Middle Cranial Fossa, Craniovertebral Junction, Posterior Cranial Fossa, Inflammatory, Sarcomas, and Anatomy. Within each section, either common findings in those skull areas or different types of sarcomas or inflammatory conditions and their imaging are detailed. The anatomy section gives examples of normal anatomy from which to compare findings against. All current imaging techniques are covered, including: CT, MRI, US, angiography, CT cisternography, nuclear medicine and plain film radiography. Each chapter additionally includes key points, classic clues, incidence, differential diagnosis, recommended treatment, and prognosis. Skull Base Imaging provides a clear and concise reference for all physicians who encounter patients with these complex and relatively rare maladies.
Author: Richard G. Ellenbogen
Publisher: Elsevier Health Sciences
ISBN: 0323461271
Category : Medical
Languages : en
Pages : 848
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Book Description
Perfect for anyone considering or training in this challenging specialty, Principles of Neurological Surgery, 4th Edition, by Drs. Richard G. Ellenbogen, Laligam N. Sekhar, and Neil Kitchen, provides a clear, superbly illustrated introduction to all aspects of neurosurgery–from general principles to specific techniques. Thorough updates from leading authors ensure that you’ll stay abreast of the latest advances in every area of neurosurgery, including pre- and post-operative patient care, neuroradiology, pediatric neurosurgery, neurovascular surgery, trauma surgery, spine surgery, oncology, pituitary adenomas, cranial base neurosurgery, image-guided neurosurgery, treatment of pain, epilepsy surgery, and much more.
Author: Ramez Kirollos
Publisher: Oxford University Press, USA
ISBN: 0198746709
Category : Medical
Languages : en
Pages : 1177
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Book Description
Neurosurgery is a rapidly developing and technically demanding branch of surgery that requires a detailed knowledge of the basic neuro-sciences and a thorough clinical approach. The Oxford Textbook of Neurological Surgery is an up-to-date, objective and readable text that covers the full scope of neurosurgical practice. It is part of the Oxford Textbooks in Surgery series, edited by Professor Sir Peter Morris. The book is split into 20 overarching sections (Principles of Neurosurgery, Neuro-oncology of Intrinsic Tumours; Extra-axial Tumours and Skull Lesions; Cerebro-Pontine Angle Tumours; Sellar and Supra-Sellar Tumours; Posterior Fossa Tumours; Pineal tumours; Uncommon Tumours and Tumour Syndromes; Neurotrauma and Intensive Care; Vascular Neurosurgery; Principles of Spinal Surgery; Spinal Pathology; Spinal Trauma; Peripheral Nerve Surgery; Functional Neurosurgery; Epilepsy; Paediatric Neurosurgery; Neurosurgery for Cerebrospinal Fluid Disorders and Neurosurgical Infection). Each section takes a dual approach with, 'Generic Surgical Management' chapters that focus on specific clinical problems facing the neurosurgeon (e.g. sellar/supra-sellar tumour, Intradural Spina Tumours etc.) and 'Pathology-Specific' chapters (e.g. Glioma, Meningeal Tumours, Scoliosis and Spinal Deformity, Aneurysm etc.). Where appropriate, this division provides the reader with easily accessible information for both clinical problems which present in a regional fashion and specific pathologies. The generic chapters cover aspects such as operative approaches, neuroanatomy and nuances. Specifically each chapter in the book incorporates several strands. Firstly the fundamental neuroscience (anatomy, pathology, genetics etc.) that underlies the clinical practice. Secondly, a review of the requisite clinical investigations (e.g. angiography, electrodiagnostics, radiology). Thirdly, a thorough evidence based review of clinical practice. Following this a consideration of the key debates and controversies in the field with 'pro-' and 'con-' sections (e.g. minimally invasive spine surgery, microsurgical treatment of aneurysms) is provided. A summary of the key papers and clinical scales relevant to neurosurgery form the concluding part. The book is a 'one-stop' text for trainees and consultants in neurosurgery, residents, those preparing for sub-specialty exams and other professionals allied to surgery who need to gain an understanding of the field. It acts as both a point of reference to provide a focussed refresher for the experienced neurosurgeon as well as a trusted training resource.
