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Author: Gerhard Buurmann
Publisher: Walter de Gruyter
ISBN: 3764376775
Category : Architecture
Languages : en
Pages : 368
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Book Description
Interactivity is the catchword for a wide range of innovative solutions that concept designers and engineers are developing in every area of technology and culture. For the authors interaction is more than a technological or aesthetic concept, it is a new means to ally humans and technology in a dynamic and reciprocal form of “living in technology”. This publication gathers together scientists and contributors from diverse fields of activity, providing a fascinating, up-to-date survey of the technological and conceptual equipment of experts engaged in aesthetic disciplines and product design. The editor, Professor Gerhard M. Buurman, is Head of Interactiondesign at the University of Art, Media and Design (HGKZ) in Zurich.
Author: Gerhard Buurmann
Publisher: Walter de Gruyter
ISBN: 3764376775
Category : Architecture
Languages : en
Pages : 368
Get Book
Book Description
Interactivity is the catchword for a wide range of innovative solutions that concept designers and engineers are developing in every area of technology and culture. For the authors interaction is more than a technological or aesthetic concept, it is a new means to ally humans and technology in a dynamic and reciprocal form of “living in technology”. This publication gathers together scientists and contributors from diverse fields of activity, providing a fascinating, up-to-date survey of the technological and conceptual equipment of experts engaged in aesthetic disciplines and product design. The editor, Professor Gerhard M. Buurman, is Head of Interactiondesign at the University of Art, Media and Design (HGKZ) in Zurich.
Author: Kosuke Ohsawa
Publisher: Springer
ISBN: 4431554475
Category : Science
Languages : en
Pages : 109
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Book Description
This book focuses on thielocin B1 (TB1), which was found to be an inhibitor of protein–protein interactions (PPIs) of proteasome assembling chaperone (PAC) 3 homodimer, and elucidates the mechanism by nuclear magnetic resonance (NMR) studies. Interfaces of PPIs recently have been expected to be novel therapeutic targets, while it is difficult to apply conventional methodology based on lock and key theory. The author achieved the first total synthesis of TB1 and its spin-labeled derivative to carry out NMR experiments because the supply of TB1 from natural sources was limited. Unique 2,2’,6,6’-tetrasubstituted diphenyl ether moiety of TB1 was synthesized from a depsidone skeleton by chemoselective reduction of lactone. In the process of elongating side wings, efficient formylation utilizing dichloromethyl methyl ether–silver trifluoromethanesulfonate was developed for the sterically hindered aromatic compound. NMR titration experiments and paramagnetic relaxation enhancement observation of PAC3 homodimer were performed with synthesized TB1 and its molecular probe, respectively. The results of the above NMR studies and additional in silico docking studies suggested that TB1 promotes the dissociation to monomeric PAC3 after interaction with PAC3 homodimer. The rare mechanism shown in this book indicates a potential novel drug target in the interfaces of PPIs with no cavity or groove.
Author: Weibo Cai
Publisher: BoD – Books on Demand
ISBN: 9535103970
Category : Science
Languages : en
Pages : 488
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Book Description
Proteins are indispensable players in virtually all biological events. The functions of proteins are coordinated through intricate regulatory networks of transient protein-protein interactions (PPIs). To predict and/or study PPIs, a wide variety of techniques have been developed over the last several decades. Many in vitro and in vivo assays have been implemented to explore the mechanism of these ubiquitous interactions. However, despite significant advances in these experimental approaches, many limitations exist such as false-positives/false-negatives, difficulty in obtaining crystal structures of proteins, challenges in the detection of transient PPI, among others. To overcome these limitations, many computational approaches have been developed which are becoming increasingly widely used to facilitate the investigation of PPIs. This book has gathered an ensemble of experts in the field, in 22 chapters, which have been broadly categorized into Computational Approaches, Experimental Approaches, and Others.
Author:
Publisher:
ISBN:
Category : Fishes
Languages : en
Pages : 1102
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Book Description
Author: Masatoshi Sato
Publisher: John Benjamins Publishing Company
ISBN: 9027267170
Category : Language Arts & Disciplines
Languages : en
Pages : 399
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Book Description
This volume represents the first collection of empirical studies focusing on peer interaction for L2 learning. These studies aim to unveil the impact of mediating variables such as task type, mode of interaction, and social relationships on learners’ interactional behaviors and language development in this unique and pedagogically powerful learning context. To examine these issues, contributors employed quantitative, qualitative, and mixed-methods designs as well as cognitive, social, and sociocognitive theoretical frameworks. The majority of the studies are classroom based and were conducted in a rich array of settings covering five continents and encompassing a wide range of learner L1s and target languages. These settings include second and foreign language classrooms from primary to university level, content-based programs, online contexts, and after-school programs. To span the divide between research and practice, each study includes a section suggesting pedagogical implications.
Author: Amritanshu Shukla
Publisher: CRC Press
ISBN: 1000172686
Category : Science
Languages : en
Pages : 402
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Book Description
Nuclear structure Physics connects to some of our fundamental questions about the creation of universe and its basic constituents. At the same time, precise knowledge on the subject has lead to develop many important tools of human kind such as proton therapy, radioactive dating etc. This book contains chapters on some of the crucial and trending research topics in nuclear structure, including the nuclei lying on the extremes of spin, isospin and mass. A better theoretical understanding of these topics is important beyond the confines of the nuclear structure community. Additionally, the book will showcase the applicability and success of the different nuclear effective interaction parameters near the drip line, where hints for level reordering have already been seen, and where one can test the isospin-dependence of the interaction. The book offers comprehensive coverage of the most essential topics, including: • Nuclear Structure of Nuclei at or Near Drip-Lines • Synthesis challenges and properties of Superheavy nuclei • Nuclear Structure and Nuclear models - Ab-initio calculations, cluster models, Shell-model/DSM, RMF, Skyrme • Shell Closure, Magicity and other novel features of nuclei at extremes • Structure of Toroidal, Bubble Nuclei, halo and other exotic nuclei These topics are not only very interesting from theoretical nuclear physics perspective but are also quite complimentary for ongoing nuclear physics experimental program worldwide. It is hoped that the book chapters written by experienced and well known researchers/experts will be helpful for the master students, graduate students and researchers and serve as a standard & uptodate research reference book on the topics covered.
Author: Godfrey Beddard
Publisher: Oxford University Press, USA
ISBN: 0199230919
Category : Mathematics
Languages : en
Pages : 806
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Book Description
Godfrey Beddard is Professor of Chemical Physics in the School of Chemistry, University of Leeds, where his research interests encompass femtosecond spectroscopy, electron and energy transfer, and protein folding and unfolding. 1. Numbers, Basic Functions, and Algorithms 2. Complex Numbers 3. Differentiation 4. Integration 5. Vectors 6. Matrices and Determinants 7. Matrices in Quantum Mechanics 8. Summations, Series, and Expansion of Functions 9. Fourier Series and Transforms 10. Differential Equations 11. Numerical Methods 12. Monte-carlo Methods 13. Statistics and Data Analysis
Author: Claude Leroy
Publisher: World Scientific
ISBN: 9814360511
Category : Science
Languages : en
Pages : 1041
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Book Description
This book, like the first and second editions, addresses the fundamental principles of interaction between radiation and matter and the principles of particle detection and detectors in a wide scope of fields, from low to high energy, including space physics and medical environment. It provides abundant information about the processes of electromagnetic and hadronic energy deposition in matter, detecting systems, performance of detectors and their optimization.The third edition includes additional material covering, for instance: mechanisms of energy loss like the inverse Compton scattering, corrections due to the Landau?Pomeranchuk?Migdal effect, an extended relativistic treatment of nucleus?nucleus screened Coulomb scattering, and transport of charged particles inside the heliosphere. Furthermore, the displacement damage (NIEL) in semiconductors has been revisited to account for recent experimental data and more comprehensive comparisons with results previously obtained.This book will be of great use to graduate students and final-year undergraduates as a reference and supplement for courses in particle, astroparticle, space physics and instrumentation. A part of the book is directed toward courses in medical physics. The book can also be used by researchers in experimental particle physics at low, medium, and high energy who are dealing with instrumentation.
Author: Geoffrey Maruyama
Publisher: John Wiley & Sons
ISBN: 1118764978
Category : Psychology
Languages : en
Pages : 576
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Book Description
Research Methods in Social Relations, 8th Edition, features a series of updates and revisions in its comprehensive introduction to current research methods in the social and behavioural sciences. Offers comprehensive coverage of a wide variety of traditional and topical research methods Addresses many newer research approaches such as propensity score matching, mixed methods designs, and confirmatory factor analysis Written to be accessible to a range of social and behavioural science disciplines, including public health, political science, sociology, and psychology Includes new chapters that engage readers in critical thinking about the processes involved in building sustainable partnerships in field and community settings The Companion website includes an array of resources for Instructors, including Test Banks, Power Point lecture slides, discussion questions and exercises This new edition is the much-anticipated follow-up to 2001’s seventh edition by Hoyle, Harris and Judd
Author: Bill Moggridge
Publisher:
ISBN:
Category : Architecture
Languages : en
Pages : 802
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Book Description
Accompanying DVD contains filmed interviews with many of the designer/inventors in the book.
