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Author: Ali Yadollahpour
Publisher: Frontiers Media SA
ISBN: 2832541275
Category : Science
Languages : en
Pages : 169
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Book Description
Personalized or precision medicine (PM) is developing and adopting of the safest and most cost-effective therapeutic approach for each patient. PM approach aims to identify phenotypic and genotypic individual characteristics, observe how these parameters are correlated with the disease status, severity, and intervention responsiveness to predict the best personalized clinical protocol. On the other hand, the risk of severe toxicity and adverse effects might be related to the patient-specific characteristics.
Author: Ali Yadollahpour
Publisher: Frontiers Media SA
ISBN: 2832541275
Category : Science
Languages : en
Pages : 169
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Book Description
Personalized or precision medicine (PM) is developing and adopting of the safest and most cost-effective therapeutic approach for each patient. PM approach aims to identify phenotypic and genotypic individual characteristics, observe how these parameters are correlated with the disease status, severity, and intervention responsiveness to predict the best personalized clinical protocol. On the other hand, the risk of severe toxicity and adverse effects might be related to the patient-specific characteristics.
Author: Evian Gordon
Publisher: Oxford University Press
ISBN: 0195393805
Category : Language Arts & Disciplines
Languages : en
Pages : 346
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Book Description
This book takes an in depth and hard look at the current status and future direction of treatment predictive markers in Personalized Medicine for the brain from the perspectives of the researchers on the cutting edge and those involved in healthcare implementation. The contents provide a comprehensive text suitable as both a pithy introduction to and a clear summary of the "science to solutions" continuum in this developing field of Personalized Medicine and Integrative Neuroscience. The science includes both measures of genes using whole genome approaches and SNIPS as well as BRAINmarkers of direct brain function such as brain imaging, biophysical changes and objective cognitive and behavioral measurements. Personalized Medicine for Brain Disorders will soon be a reality using the comprehensive quantitative and standardized approaches to genomics, BRAINmarkers and cognitive function. Each chapter provides a review of recent relevant literature; show the solutions achieved through integrative neuroscience and applications in patient care thus providing a practical guide to the reader. The timeliness of this book's content is propitious providing bottom line information to educate practicing clinicians, health care workers and researchers, and also a pathway for undergraduate and graduates interested in further their understanding of and involvement in tailored personal solutions.
Author:
Publisher: Academic Press
ISBN: 0123822289
Category : Science
Languages : en
Pages : 1350
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Book Description
Genomic and Personalized Medicine, Second Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — is a major discussion of the structure, history, and applications of the field, as it emerges from the campus and lab into clinical action. As with the first edition, leading experts review the development of the new science, the current opportunities for genome-based analysis in healthcare, and the potential of genomic medicine in future healthcare. The inclusion of the latest information on diagnostic testing, population screening, disease susceptability, and pharmacogenomics makes this work an ideal companion for the many stakeholders of genomic and personalized medicine. With advancing knowledge of the genome across and outside protein-coding regions of DNA, new comprehension of genomic variation and frequencies across populations, the elucidation of advanced strategic approaches to genomic study, and above all in the elaboration of next-generation sequencing, genomic medicine has begun to achieve the much-vaunted transformative health outcomes of the Human Genome Project, almost a decade after its official completion in April 2003. Highly Commended 2013 BMA Medical Book Award for Medicine More than 100 chapters, from leading researchers, review the many impacts of genomic discoveries in clinical action, including 63 chapters new to this edition Discusses state-of-the-art genome technologies, including population screening, novel diagnostics, and gene-based therapeutics Wide and inclusive discussion encompasses the formidable ethical, legal, regulatory and social challenges related to the evolving practice of genomic medicine Clearly and beautifully illustrated with 280 color figures, and many thousands of references for further reading and deeper analysis
Author: Matthew James Farrer
Publisher: Frontiers Media SA
ISBN: 2889662519
Category : Medical
Languages : en
Pages : 106
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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author: Geoffrey S. Ginsburg
Publisher: Academic Press
ISBN: 9780080958118
Category : Science
Languages : en
Pages : 850
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Book Description
Derived from the comprehensive two-volume set, Genomic and Personalized Medicine also edited by Drs. Willard and Ginsburg, this work serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing one of the most promising avenues for advances in diagnosis, prevention and treatment of human disease. From principles, methodology and translational approaches to genome discoveries and clinical applications, Essentials of Genomic and Personalized Medicine will be a valuable resource for various professionals and students across medical disciplines, including human genetics and genomics, oncology, neuroscience, gene therapy, molecular medicine, pharmacology, and biomedical sciences. Updates with regard to diagnostic testing, pharmacogenetics, predicting disease susceptibility, and other important research components as well as chapters dedicated to cardiovascular disease, oncology, inflammatory disease, metabolic disease, neuropsychiatric disease, and infectious disease, present this book as an essential tool for a variety of professionals and students who are endeavouring into the developing the diverse and practical field of genomic and personalized medicine. * Full color throughout * Includes contributions on genetic counselling, ethical, legal/regulatory, and social issues related to the practice of genomic medicine from leaders in the field * Introductory chapter highlights differences between personalized and traditional medicine, promising areas of current research, and challenges to incorporate the latest research discoveries and practice * Ancillary material includes case studies and lab questions which highlight the collaborative approach to the science
Author: Drozdstoy Stoyanov
Publisher: Springer Nature
ISBN: 1071632302
Category : Medical
Languages : en
Pages : 275
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Book Description
This volume looks at the latest advancements in imaging neuroscience methods using magnetic resonance imaging (MRI) and electroencephalography (EEG) to study the healthy and diseased brain. The chapters in this book are organized into five parts. Parts One and Two cover an introduction to this field and the latest use of molecular models. Part Three explores neurophysiological methods for assessment, such as quantitative EEG and event-related potentials. Part Four discusses the advances and innovations made in computational anatomy, and Part Five addresses the challenges faced by researchers prior to the computational neuroscience to find wider translational applications in the field of psychiatry and mental health. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Computational Neuroscience is a valuable tool for researchers in the psychiatry and mental health fields who want to learn more about ways to incorporate computational approaches into utility and validity of clinical methods.
Author: Peter J. Whitehouse, M.D.
Publisher: St. Martin's Press
ISBN: 1429920718
Category : Health & Fitness
Languages : en
Pages : 336
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Book Description
Dr. Peter Whitehouse will transform the way we think about Alzheimer's disease. In this provocative and ground-breaking book he challenges the conventional wisdom about memory loss and cognitive impairment; questions the current treatment for Alzheimer's disease; and provides a new approach to understanding and rethinking everything we thought we knew about brain aging. The Myth of Alzheimer's provides welcome answers to the questions that millions of people diagnosed with Alzheimer's disease – and their families – are eager to know: Is Alzheimer's a disease? What is the difference between a naturally aging brain and an Alzheimer's brain? How effective are the current drugs for AD? Are they worth the money we spend on them? What kind of hope does science really have for the treatment of memory loss? And are there alternative interventions that can keep our aging bodies and minds sharp? What promise does genomic research actually hold? What would a world without Alzheimer's look like, and how do we as individuals and as human communities get there? Backed up by research, full of practical advice and information, and infused with hope, THE MYTH OF ALZHEIMER'S will liberate us from this crippling label, teach us how to best approach memory loss, and explain how to stave off some of the normal effects of aging. Peter J. Whitehouse, M.D., Ph.D., one of the best known Alzheimer's experts in the world, specializes in neurology with an interest in geriatrics and cognitive science and a focus on dementia. He is the founder of the University Alzheimer Center (now the University Memory and Aging Center) at University Hospitals Case Medical Center and Case Western Reserve University where he has held professorships in the neurology, neuroscience, psychiatry, psychology, organizational behavior, bioethics, cognitive science, nursing, and history. He is also currently a practicing geriatric neurologist. With his wife, Catherine, he founded The Intergenerational School, an award winning, internationally recognized public school committed to enhancing lifelong cognitive vitality. Daniel George, MSc, is a research collaborator with Dr. Whitehouse at Case Western Reserve University in Cleveland, Ohio, and is currently pursuing a Doctorate in Medical Anthropology at Oxford University in England. "I don't have a magic bullet to prevent your brain from getting older, and so I don't claim to have the cure for AD; but I do offer a powerful therapy—a new narrative for approaching brain aging that undercuts the destructive myth we tell today. Most of our knowledge and our thinking is organized in story form, and thus stories offer us the chief means of making sense of the present, looking into the future, and planning and creating our lives. New approaches to brain aging require new stories that can move us beyond the myth of Alzheimer's disease and towards improved quality of life for all aging persons in our society. It is in this book that your new story can begin." -Peter Whitehouse, M.D., Ph.D.
Author: Bernhard Baune
Publisher: Academic Press
ISBN: 0128131772
Category : Medical
Languages : en
Pages : 604
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Book Description
Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective
Author: Qing Yan
Publisher: Academic Press
ISBN: 0128043881
Category : Computers
Languages : en
Pages : 182
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Book Description
Translational Bioinformatics and Systems Biology Methods for Personalized Medicine introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine. Through the description of important cutting-edge technologies in bioinformatics and systems biology, readers may gain an essential understanding of state-of-the-art methodologies. The book discusses topics such as the challenges and tasks in translational bioinformatics; pharmacogenomics, systems biology, and personalized medicine; and the applicability of translational bioinformatics for biomarker discovery, epigenomics, and molecular dynamics. It also discusses data integration and mining, immunoinformatics, and neuroinformatics. With broad coverage of both basic scientific and clinical applications, this book is suitable for a wide range of readers who may not be scientists but who are also interested in the practice of personalized medicine. Introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine Presents a problem-solving oriented methodology to deal with practical problems in various applications Covers both basic scientific and clinical applications in order to enhance the collaboration between researchers and clinicians Brings integrative and multidisciplinary approaches to bridge the gaps among various knowledge domains in the field
Author: Sanket Joshi
Publisher: Springer Nature
ISBN: 9819994624
Category :
Languages : en
Pages : 587
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Book Description
