Negative Affective States and Cognitive Impairments in Nicotine Dependence

Negative Affective States and Cognitive Impairments in Nicotine Dependence PDF Author: F. Scott Hall
Publisher: Academic Press
ISBN: 0128026693
Category : Medical
Languages : en
Pages : 362

Get Book

Book Description
Negative Affective States and Cognitive Impairments in Nicotine Dependence is the only book of its kind that addresses nicotine use and abuse in the context of negative reinforcement mechanisms. Written and edited by leading investigators in addiction, affective, genetic, and cognitive research, it provides researchers and advanced students with an overview of the clinical bases of these effects, allowing them to fully understand the various underlying dysfunctions that drive nicotine use in different individuals. In addition, this book examines animal models that researchers have utilized to investigate the biological bases of these dysfunctions. The combination of clinical and preclinical approaches to understanding nicotine dependence makes this book an invaluable resource for researchers and practitioners seeking to develop targeted treatments aimed at ameliorating symptoms of nicotine dependence, as well as identifying premorbid differences in affective or cognitive function. Provides a unique perspective on nicotine dependence that emphasizes negative reinforcement rather than positive reinforcement Examines psychiatric comorbidities and alleviation of withdrawal states as motivation for continued tobacco use Includes both clinical and preclinical perspectives Includes genetic and multi-neurotransmitter perspectives on nicotine use and withdrawal Emphasizes heterogeneity of underlying reasons for smoking, the need for multiple animal models to understand this heterogeneity, and the expectation of heterogeneous responses to potential treatments, underscoring the need for personalized therapeutics

Negative Affective States and Cognitive Impairments in Nicotine Dependence

Negative Affective States and Cognitive Impairments in Nicotine Dependence PDF Author: F. Scott Hall
Publisher: Academic Press
ISBN: 0128026693
Category : Medical
Languages : en
Pages : 362

Get Book

Book Description
Negative Affective States and Cognitive Impairments in Nicotine Dependence is the only book of its kind that addresses nicotine use and abuse in the context of negative reinforcement mechanisms. Written and edited by leading investigators in addiction, affective, genetic, and cognitive research, it provides researchers and advanced students with an overview of the clinical bases of these effects, allowing them to fully understand the various underlying dysfunctions that drive nicotine use in different individuals. In addition, this book examines animal models that researchers have utilized to investigate the biological bases of these dysfunctions. The combination of clinical and preclinical approaches to understanding nicotine dependence makes this book an invaluable resource for researchers and practitioners seeking to develop targeted treatments aimed at ameliorating symptoms of nicotine dependence, as well as identifying premorbid differences in affective or cognitive function. Provides a unique perspective on nicotine dependence that emphasizes negative reinforcement rather than positive reinforcement Examines psychiatric comorbidities and alleviation of withdrawal states as motivation for continued tobacco use Includes both clinical and preclinical perspectives Includes genetic and multi-neurotransmitter perspectives on nicotine use and withdrawal Emphasizes heterogeneity of underlying reasons for smoking, the need for multiple animal models to understand this heterogeneity, and the expectation of heterogeneous responses to potential treatments, underscoring the need for personalized therapeutics

Internet Gaming Disorder

Internet Gaming Disorder PDF Author: Daniel King
Publisher: Academic Press
ISBN: 0128129255
Category : Psychology
Languages : en
Pages : 294

Get Book

Book Description
Internet Gaming Disorder: Theory, Assessment, Treatment, and Prevention is an informative and practical introduction to the topics of Internet gaming disorder and problematic gaming. This book provides mental health clinicians with hands-on assessment, prevention, and treatment techniques for clients with problematic gaming behaviors and Internet gaming disorder. It provides an overview of the existing research on epidemiology, risk and protective factors, and discusses the distinct cognitive features that distinguish gaming from gambling and other related activities and disorders. Clinicians will find interest in discussion of the latest developments in cognitive-behavioral approaches to gaming disorder as well as the best structure for clinical interviews. Included in clinical sections are details of the key indicators of harm and impairment associated with problem gaming and how these might present in clinical cases. Internet Gaming Disorder is strongly evidence-based, draws extensively upon the latest international research literature, and provides insights into the likely future developments in this emerging field both in terms of technological development and new research approaches. Discusses the conceptual basis of Internet gaming disorder as a behavioral addiction Provides screening approaches for measuring excessive gaming Details a structured clinical interview approach for assessing gaming disorder Provides evidence-based clinical strategies for prevention and treatment Covers cognitive behavioral therapy and harm reduction strategies

Drugs, Addiction, and the Brain

Drugs, Addiction, and the Brain PDF Author: George F. Koob
Publisher: Academic Press
ISBN: 0123869595
Category : Medical
Languages : en
Pages : 351

Get Book

Book Description
Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle Actual data figures from original sources illustrating key concepts and findings Introduction to basic neuropharmacology terms and concepts Introduction to numerous animal models used to study diverse aspects of drug use. Thorough review of extant work on the neurobiology of addiction

Neuroscience of Nicotine

Neuroscience of Nicotine PDF Author: Victor R. Preedy
Publisher: Academic Press
ISBN: 0128130369
Category : Medical
Languages : en
Pages : 566

Get Book

Book Description
Neuroscience of Nicotine: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of nicotine addiction and its effects on the brain. Offering thorough coverage of all aspects of nicotine research, treatment, policy and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of nicotine misuse. With an estimated one billion individuals worldwide classified as tobacco users—and tobacco use often being synonymous with nicotine addiction—nicotine is one of the world’s most common addictive substances, and a frequent comorbidity of misuse of other common addictive substances. Nicotine alters a variety of neurological processes, from molecular biology, to cognition, and quitting is exceedingly difficult because of the number of withdrawal symptoms that accompany the process. Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of nicotine use, along with its effects on neurobiological function Discusses nicotine use as a component of dual-use and poly addictions and outlines numerous screening and treatment strategies for misuse Covers both the physical and psychological effects of nicotine use and withdrawal to provide a fully-formed view of nicotine dependency and its effects

The Tobacco Epidemic

The Tobacco Epidemic PDF Author: R. Loddenkemper
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318026573
Category : Psychology
Languages : en
Pages : 276

Get Book

Book Description
This completely revised and enlarged 2nd edition of The Tobacco Epidemic provides a comprehensive update of the clinical, public health and political aspects of tobacco smoking. Since its 1st edition in 1997, knowledge on the health hazards of tobacco and nicotine addiction has increased considerably, but recent data has shown that the global problem has become more aggravated in low- and middle-income countries: if current trends continue, tobacco smoking will be responsible for the deaths of 1 billion people in the 21st century. Written by outstanding international experts, the book covers the history of tobacco production and use, the economics of tobacco use and control, as well as the health consequences of active and passive smoking in both adults and children. Special chapters discuss the impact of media, movies and TV on tobacco consumption in young people, the patterns and predictors of smoking cessation in the general population and in different social subgroups, and initiatives supported by the WHO Framework Convention on Tobacco Control. Readers will find the latest information on how nicotine dependence is treated with nicotine replacement products, what role health care professionals play in helping smokers to quit and what effects smoke-free environments, advertising bans and price increases have on smoking prevalence. The potential harms and benefits of smokeless tobacco, waterpipe tobacco smoking and electronic cigarettes are also evaluated. This book is a must-read for anyone in the medical profession who treats patients with smoking-related diseases and for those engaged in tobacco control. It will also be appreciated by interested nonmedical readers like journalists and legislators.

Anhedonia: Preclinical, Translational, and Clinical Integration

Anhedonia: Preclinical, Translational, and Clinical Integration PDF Author: Diego A. Pizzagalli
Publisher: Springer Nature
ISBN: 3031096835
Category : Medical
Languages : en
Pages : 526

Get Book

Book Description
Anhedonia is a key symptom (and often risk factor) for various neuropsychiatric disorders, including depression, schizophrenia, substance use disorders, post-traumatic stress disorders, and Parkinson's Disease, among others. Across disorders, anhedonia has been associated with worse disease course, including poor response to pharmacological, psychological and neurostimulation treatments as well as completed suicide. Mounting evidence emerging from preclinical and translational sciences has clarified that "anhedonia" can be parsed into partially independent subcomponents, including incentive motivation, consummatory pleasure, reward learning, and effort-based decision making, pointing to distinct neurobiological substrates that could underlie anhedonic phenotypes. Taking an integrative approach that emphasizes cross-species integration and dimensional conceptualization of mental illnesses (e.g., Research Domain Criteria (RDoC)), this book represents the most comprehensive evaluation, synthesis and integration of theories and empirical findings focused on anhedonia. Organized across five parts, the handbook starts with chapters on the history, etiology, and assessments of anhedonia (Part I), followed by a section on the role of anhedonia in psychiatric and neurological disorders (Part II). Using the RDoC Matrix as a guide, Part III presents chapters synthetizing preclinical and clinical findings on different reward processing subdomains (e.g., reward responsiveness, reward valuation, reward learning). Part IV is focused on selected special topics, including historical and current perspectives on the transdiagnostic nature and importance of social anhedonia, the role of inflammation in the pathophysiology of anhedonia, the use of computational modeling to “dissect” anhedonia and improve its understanding, and links between anhedonia and suicide. Finally, Part V includes chapters on pharmacological, psychological and neurostimulation treatments for anhedonia.

Brain and Cognition for Addiction Medicine: From Prevention to Recovery

Brain and Cognition for Addiction Medicine: From Prevention to Recovery PDF Author: Hamed Ekhtiari
Publisher: Frontiers Media SA
ISBN: 2889663779
Category : Science
Languages : en
Pages : 413

Get Book

Book Description


Sleep and Health

Sleep and Health PDF Author: Michael Grandner
Publisher: Academic Press
ISBN: 0128153741
Category : Science
Languages : en
Pages : 531

Get Book

Book Description
Sleep and Health provides an accessible yet comprehensive overview of the relationship between sleep and health at the individual, community and population levels, as well as a discussion of the implications for public health, public policy and interventions. Based on a firm foundation in many areas of sleep health research, this text further provides introductions to each sub-area of the field and a summary of the current research for each area. This book serves as a resource for those interested in learning about the growing field of sleep health research, including sections on social determinants, cardiovascular disease, cognitive functioning, health behavior theory, smoking, and more. Highlights the important role of sleep across a wide range of topic areas Addresses important topics such as sleep disparities, sleep and cardiometabolic disease risk, real-world effects of sleep deprivation, and public policy implications of poor sleep Contains accessible reviews that point to relevant literature in often-overlooked areas, serving as a helpful guide to all relevant information on this broad topic area

Memory Systems of the Addicted Brain: The Underestimated Role of Drug-Induced Cognitive Biases in Addiction and Its Treatment

Memory Systems of the Addicted Brain: The Underestimated Role of Drug-Induced Cognitive Biases in Addiction and Its Treatment PDF Author: Vincent David
Publisher: Frontiers Media SA
ISBN: 2889454878
Category :
Languages : en
Pages : 163

Get Book

Book Description
Drug addiction may be viewed as a form of learning during which strong associations linking actions to drug-seeking are expressed as persistent stimulus–response habits, thereby maintaining a vulnerability to relapse. Disrupting cue–drug memory could be an efficient strategy to reduce the strength of cues in motivating drug-taking behavior. Upon reactivation, these memories undergo a reconsolidation process that can be blocked pharmacologically, providing an opportunity to prevent the powerful control of drug cues on behavior. This conceptually elegant approach still calls for more experimental data. However, an increasing body of evidence suggests that drug taking not only accelerates habit forming, but has long-lasting effects on interactions between memory systems eventually leading to a functional imbalance. The dorsal part of the striatum plays a critical role in habit/procedural learning, whereas the hippocampal memory system encodes relationships between events and their later flexible use. Both humans and rodents studies support the view that the hippocampus and the dorsal striatum interact in either a cooperative or competitive manner during learning, the prefrontal cortex being involved in the selection of an appropriate learning strategy. Chronic drug consumption biases normal interactions between these memory systems. For instance, drug-experienced rodents tend to use preferentially striatum-dependent learning strategies in navigational tasks. These persistent effects seem to occur at cellular, neurophysiological and behavioral levels to promote specific, striatal-dependent forms of learning, to the detriment of spatial/declarative, hippocampal-dependent and more flexible types of memory. Whether cue sensitive and response learners, in contrast to spatial learners, could be prone to drug addiction is an intriguing hypothesis which clearly deserves to be further explored. A loss of flexibility may be uncovered also by imposing changing rules on the subject, such as requiring an attentional shift between different perceptual features of a complex stimulus, as in the attentional set shifting task which was recently adapted to rodents. Working memory is at risk during transition phases, although it remains to be determined whether withdrawal-induced alterations are observed also during protracted abstinence. Drug-induced cognitive biases thus lead to cognitive rigidity which could play a critical, yet overlooked role in different phases of addiction (acquisition, extinction/withdrawal and relapse). They are also likely to preclude the clinical efficiency of treatments. Therefore, the aim of this research topic is to provide an overview of the current work investigating the long-term impact of drug use on learning and memory processes, how multiple memory systems modulate drug-seeking behavior, as well as how drug-induced cognitive biases could contribute to the persistence of addictive behaviors.

Essential Psychiatry

Essential Psychiatry PDF Author: Robin M. Murray
Publisher: Cambridge University Press
ISBN: 1139473654
Category : Medical
Languages : en
Pages :

Get Book

Book Description
This is a major international textbook for psychiatrists and other professionals working in the field of mental healthcare. With contributions from opinion-leaders from around the globe, this book will appeal to those in training as well as to those further along the career path seeking a comprehensive and up-to-date overview of effective clinical practice backed by research evidence. The book is divided into cohesive sections moving from coverage of the tools and skills of the trade, through descriptions of the major psychiatric disorders and on to consider special topics and issues surrounding service organization. The final important section provides a comprehensive review of treatments covering all of the major modalities. Previously established as the Essentials of Postgraduate Psychiatry, this new and completely revised edition is the only book to provide this depth and breadth of coverage in an accessible, yet authoritative manner.